The molecular interface between cell cycle and redox regulation

Información del proyecto

REDOXCYCLE

Identificador del acuerdo de subvención: 680042

DOI 10.3030/680042

Proyecto cerrado

Fecha de la firma de la CE 25 Enero 2016

Fecha de inicio 1 Julio 2016

Fecha de finalización 31 Diciembre 2021

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total € 1 499 688,00

Aportación de la UE € 1 499 688,00

Coordinado por

INSTITUTE OF CANCER RESEARCH: THE ROYAL CANCER HOSPITAL LBG
United Kingdom

Publicaciones

Peer reviewed articles (12)

Efficient and gentle delivery of molecules into cells with different elasticity via Progressive Mechanoporation

Autores: Alena Uvizl, Ruchi Goswami, Shanil Durgeshkumar Gandhi, Martina Augsburg, Frank Buchholz, Jochen Guck, Jörg Mansfeld ORCID and Salvatore Girardo
Publicado en: Lab on a Chip, 2021, ISSN 1473-0197
Editor: Royal Society of Chemistry
DOI: 10.1039/d0lc01224f

A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase

Autores: Dilyana Georgieva Kirova Kristyna Judasova Thomas Zerjatke Ingmar Glauche
Publicado en: Developmental Cell, 2022, ISSN 1534-5807
Editor: Cell Press
DOI: 10.1016/j.devcel.2022.06.008

ROS Dynamics Delineate Functional States of Hippocampal Neural Stem Cells and Link to Their Activity-Dependent Exit from Quiescence

Autores: Vijay S. Adusumilli, Tara L. Walker, Rupert W. Overall, Gesa M. Klatt, Salma A. Zeidan, Sara Zocher, Dilyana G. Kirova, Konstantinos Ntitsias, Tim J. Fischer, Alex M. Sykes, Susanne Reinhardt, Andreas Dahl, Jörg Mansfeld, Annette E. Rünker, Gerd Kempermann
Publicado en: Cell Stem Cell, Edición 28/2, 2021, Página(s) 300-314.e6, ISSN 1934-5909
Editor: Cell Press
DOI: 10.1016/j.stem.2020.10.019

Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S

Autores: Anna K. L. Liess, Alena Kucerova, Kristian Schweimer, Dörte Schlesinger, Olexandr Dybkov, Henning Urlaub, Jörg Mansfeld, Sonja Lorenz
Publicado en: Science Signaling, Edición 13/654, 2020, Página(s) eaba8208, ISSN 1937-9145
Editor: American Association for the Advancement of Science
DOI: 10.1126/scisignal.aba8208

Quantitative Cell Cycle Analysis Based on an Endogenous All-in-One Reporter for Cell Tracking and Classification

Autores: Thomas Zerjatke, Igor A. Gak, Dilyana Kirova, Markus Fuhrmann, Katrin Daniel, Magdalena Gonciarz, Doris Müller, Ingmar Glauche, Jörg Mansfeld
Publicado en: Cell Reports, Edición 19/9, 2017, Página(s) 1953-1966, ISSN 2211-1247
Editor: Cell Press
DOI: 10.1016/j.celrep.2017.05.022

Distinct Levels of Reactive Oxygen Species Coordinate Metabolic Activity with Beta-cell Mass Plasticity

Autores: Ezzaldin Ahmed Alfar, Dilyana Kirova, Judith Konantz, Sarah Birke, Jörg Mansfeld, Nikolay Ninov
Publicado en: Scientific Reports, Edición 7/1, 2017, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-017-03873-9

PLK1 Activation in Late G2 Sets Up Commitment to Mitosis

Autores: Lilia Gheghiani, Damarys Loew, Bérangère Lombard, Jörg Mansfeld, Olivier Gavet
Publicado en: Cell Reports, Edición 19/10, 2017, Página(s) 2060-2073, ISSN 2211-1247
Editor: Cell Press
DOI: 10.1016/j.celrep.2017.05.031

Conditional control of fluorescent protein degradation by an auxin-dependent nanobody

Autores: Katrin Daniel, Jaroslav Icha, Cindy Horenburg, Doris Müller, Caren Norden, Jörg Mansfeld
Publicado en: Nature Communications, Edición 9/1, 2018, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-018-05855-5

Constitutive regulation of mitochondrial morphology by Aurora A kinase depends on a predicted cryptic targeting sequence at the N-terminus

Autores: Rhys Grant, Ahmed Abdelbaki, Alessia Bertoldi, Maria P. Gavilan, Jörg Mansfeld, David M. Glover, Catherine Lindon
Publicado en: Open Biology, Edición 8/6, 2018, Página(s) 170272, ISSN 2046-2441
Editor: Royal Society Publishing
DOI: 10.1098/rsob.170272

Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination

Autores: Anna K.L. Liess, Alena Kucerova, Kristian Schweimer, Lu Yu, Theodoros I. Roumeliotis, Mathias Diebold, Olexandr Dybkov, Christoph Sotriffer, Henning Urlaub, Jyoti S. Choudhary, Jörg Mansfeld, Sonja Lorenz
Publicado en: Structure, Edición 27(8), 2019, Página(s) 1195-1210, ISSN 0969-2126
Editor: Cell Press
DOI: 10.1016/j.str.2019.05.008

An E2-ubiquitin thioester-driven approach to identify substrates modified with ubiquitin and ubiquitin-like molecules

Autores: Gábor Bakos, Lu Yu, Igor A. Gak, Theodoros I. Roumeliotis, Dimitris Liakopoulos, Jyoti S. Choudhary, Jörg Mansfeld
Publicado en: Nature Communications, Edición 9/1, 2018, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-018-07251-5

Degron-tagged reporters probe membrane topology and enable the specific labelling of membrane-wrapped structures

Autores: Katharina B. Beer, Gholamreza Fazeli, Kristyna Judasova, Linda Irmisch, Jona Causemann, Jörg Mansfeld, Ann M. Wehman
Publicado en: Nature Communications, Edición 10/1, 2019, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-019-11442-z

Non-peer reviewed articles (1)

A ROS-dependent mechanism to drive progression through S phase

Autores: Dilyana G Kirova, Kristyna Judasova, Julia Vorhauser, Thomas Zerjatke, Jacky K Leung, Ingmar Glauche and Jörg Mansfeld
Publicado en: BioRxiv, 2022, ISSN 2692-8205
Editor: BioRxiv
DOI: 10.1101/2022.03.31.486607