The molecular interface between cell cycle and redox regulation

Informazioni relative al progetto

REDOXCYCLE

ID dell’accordo di sovvenzione: 680042

DOI 10.3030/680042

Progetto chiuso

Data della firma CE 25 Gennaio 2016

Data di avvio 1 Luglio 2016

Data di completamento 31 Dicembre 2021

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 499 688,00

Contributo UE € 1 499 688,00

Coordinato da

INSTITUTE OF CANCER RESEARCH: THE ROYAL CANCER HOSPITAL LBG
United Kingdom

Pubblicazioni

Peer reviewed articles (12)

Efficient and gentle delivery of molecules into cells with different elasticity via Progressive Mechanoporation

Autori: Alena Uvizl, Ruchi Goswami, Shanil Durgeshkumar Gandhi, Martina Augsburg, Frank Buchholz, Jochen Guck, Jörg Mansfeld ORCID and Salvatore Girardo
Pubblicato in: Lab on a Chip, 2021, ISSN 1473-0197
Editore: Royal Society of Chemistry
DOI: 10.1039/d0lc01224f

A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase

Autori: Dilyana Georgieva Kirova Kristyna Judasova Thomas Zerjatke Ingmar Glauche
Pubblicato in: Developmental Cell, 2022, ISSN 1534-5807
Editore: Cell Press
DOI: 10.1016/j.devcel.2022.06.008

ROS Dynamics Delineate Functional States of Hippocampal Neural Stem Cells and Link to Their Activity-Dependent Exit from Quiescence

Autori: Vijay S. Adusumilli, Tara L. Walker, Rupert W. Overall, Gesa M. Klatt, Salma A. Zeidan, Sara Zocher, Dilyana G. Kirova, Konstantinos Ntitsias, Tim J. Fischer, Alex M. Sykes, Susanne Reinhardt, Andreas Dahl, Jörg Mansfeld, Annette E. Rünker, Gerd Kempermann
Pubblicato in: Cell Stem Cell, Numero 28/2, 2021, Pagina/e 300-314.e6, ISSN 1934-5909
Editore: Cell Press
DOI: 10.1016/j.stem.2020.10.019

Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S

Autori: Anna K. L. Liess, Alena Kucerova, Kristian Schweimer, Dörte Schlesinger, Olexandr Dybkov, Henning Urlaub, Jörg Mansfeld, Sonja Lorenz
Pubblicato in: Science Signaling, Numero 13/654, 2020, Pagina/e eaba8208, ISSN 1937-9145
Editore: American Association for the Advancement of Science
DOI: 10.1126/scisignal.aba8208

Quantitative Cell Cycle Analysis Based on an Endogenous All-in-One Reporter for Cell Tracking and Classification

Autori: Thomas Zerjatke, Igor A. Gak, Dilyana Kirova, Markus Fuhrmann, Katrin Daniel, Magdalena Gonciarz, Doris Müller, Ingmar Glauche, Jörg Mansfeld
Pubblicato in: Cell Reports, Numero 19/9, 2017, Pagina/e 1953-1966, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2017.05.022

Distinct Levels of Reactive Oxygen Species Coordinate Metabolic Activity with Beta-cell Mass Plasticity

Autori: Ezzaldin Ahmed Alfar, Dilyana Kirova, Judith Konantz, Sarah Birke, Jörg Mansfeld, Nikolay Ninov
Pubblicato in: Scientific Reports, Numero 7/1, 2017, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-017-03873-9

PLK1 Activation in Late G2 Sets Up Commitment to Mitosis

Autori: Lilia Gheghiani, Damarys Loew, Bérangère Lombard, Jörg Mansfeld, Olivier Gavet
Pubblicato in: Cell Reports, Numero 19/10, 2017, Pagina/e 2060-2073, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2017.05.031

Conditional control of fluorescent protein degradation by an auxin-dependent nanobody

Autori: Katrin Daniel, Jaroslav Icha, Cindy Horenburg, Doris Müller, Caren Norden, Jörg Mansfeld
Pubblicato in: Nature Communications, Numero 9/1, 2018, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-018-05855-5

Constitutive regulation of mitochondrial morphology by Aurora A kinase depends on a predicted cryptic targeting sequence at the N-terminus

Autori: Rhys Grant, Ahmed Abdelbaki, Alessia Bertoldi, Maria P. Gavilan, Jörg Mansfeld, David M. Glover, Catherine Lindon
Pubblicato in: Open Biology, Numero 8/6, 2018, Pagina/e 170272, ISSN 2046-2441
Editore: Royal Society Publishing
DOI: 10.1098/rsob.170272

Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination

Autori: Anna K.L. Liess, Alena Kucerova, Kristian Schweimer, Lu Yu, Theodoros I. Roumeliotis, Mathias Diebold, Olexandr Dybkov, Christoph Sotriffer, Henning Urlaub, Jyoti S. Choudhary, Jörg Mansfeld, Sonja Lorenz
Pubblicato in: Structure, Numero 27(8), 2019, Pagina/e 1195-1210, ISSN 0969-2126
Editore: Cell Press
DOI: 10.1016/j.str.2019.05.008

An E2-ubiquitin thioester-driven approach to identify substrates modified with ubiquitin and ubiquitin-like molecules

Autori: Gábor Bakos, Lu Yu, Igor A. Gak, Theodoros I. Roumeliotis, Dimitris Liakopoulos, Jyoti S. Choudhary, Jörg Mansfeld
Pubblicato in: Nature Communications, Numero 9/1, 2018, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-018-07251-5

Degron-tagged reporters probe membrane topology and enable the specific labelling of membrane-wrapped structures

Autori: Katharina B. Beer, Gholamreza Fazeli, Kristyna Judasova, Linda Irmisch, Jona Causemann, Jörg Mansfeld, Ann M. Wehman
Pubblicato in: Nature Communications, Numero 10/1, 2019, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-019-11442-z

Non-peer reviewed articles (1)

A ROS-dependent mechanism to drive progression through S phase

Autori: Dilyana G Kirova, Kristyna Judasova, Julia Vorhauser, Thomas Zerjatke, Jacky K Leung, Ingmar Glauche and Jörg Mansfeld
Pubblicato in: BioRxiv, 2022, ISSN 2692-8205
Editore: BioRxiv
DOI: 10.1101/2022.03.31.486607