Next-Generation Personalized Diagnostic Nanotechnologies for Predicting Response to Cancer Medicine

Información del proyecto

BARCODE DIAGNOSTICS

Identificador del acuerdo de subvención: 680242

DOI

10.3030/680242

Proyecto cerrado

Fecha de la firma de la CE 29 Marzo 2016

Fecha de inicio 1 Abril 2016

Fecha de finalización 31 Marzo 2022

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 1 499 250,00

Aportación de la UE

€ 1 499 250,00

Coordinado por

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Israel

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (18)

Collagenase Nanoparticles Enhance the Penetration of Drugs into Pancreatic Tumors

Autores: Assaf Zinger, Lilach Koren, Omer Adir, Maria Poley, Mohammed Alyan, Zvi Yaari, Nadav Noor, Nitzan Krinsky, Assaf Simon, Hadas Gibori, Majd Krayem, Yelena Mumblat, Shira Kasten, Sivan Ofir, Eran Fridman, Neta Milman, Michael M Lübtow, Lior Liba, Jeny Shklover, Janna Shainsky-Roitman, Yoav Binenbaum, Dov Hershkovitz, Ziv Gil, Tal Dvir, Robert Luxenhofer, Ronit Satchi-Fainaro, Avi Schroeder
Publicado en: Collagenase Nanoparticles Enhance the Penetration of Drugs into Pancreatic Tumors, Edición 22;13(10), 2019, Página(s) 11008-11021, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.9b02395

Synthetic Cells with Self-Activating Optogenetic Proteins Communicate with Natural Cells

Autores: Omer Adir, Mia R. Albalak, Ravit Abel, Lucien E. Weiss, Gal Chen, Amit Gruber, Oskar Staufer, Yaniv Kurman, Ido Kaminer, Jeny Shklover, Janna Shainsky-Roitman, Ilia Platzman, Lior Gepstein, Yoav Shechtman, Benjamin Horwitz, Avi Schroeder
Publicado en: Nature Communications, Edición 28;13(1), 2022, Página(s) 2328, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-29871-8

Preparing Protein Producing Synthetic Cells using Cell Free Bacterial Extracts, Liposomes and Emulsion Transfer

Autores: Omer Adir, Noga Sharf-Pauker, Gal Chen, Maya Kaduri, Nitzan Krinsky, Janna Shainsky-Roitman, Jeny Shklover, Avi Schroeder
Publicado en: JoVE (Journal of Visualized Experiments), 2020, ISSN 1940-087X
Editor: MYJoVE Corporation
DOI: 10.3791/60829

Nanoparticles Accumulate in the Female Reproductive System during Ovulation Affecting Cancer Treatment and Fertility

Autores: Maria Poley, Patricia Mora-Raimundo, Yael Shammai, Maya Kaduri, Lilach Koren, Omer Adir, Jeny Shklover, Janna Shainsky-Roitman, Srinivas Ramishetti, Francis Man, Rafael T. M. de Rosales, Assaf Zinger, Dan Peer, Irit Ben-Aharon, Avi Schroeder
Publicado en: ACS Nano, Edición 16/4, 2022, Página(s) 5246-5257, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.1c07237

Targeting neurons in the tumor microenvironment with bupivacaine nanoparticles reduces breast cancer progression and metastases

Autores: Maya Kaduri, Mor Sela, Shaked Kagan, Maria Poley, Hanan Abumanhal-Masarweh, Patricia Mora-Raimundo, Alberto Ouro, Nitsan Dahan, Dov Hershkovitz, Jeny Shklover, Janna Shainsky-Roitman, Yosef Buganim, Avi Schroeder
Publicado en: Science Advances, Edición 7/41, 2021, ISSN 0036-8075
Editor: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abj5435

Lung targeted liposomes for treating ARDS

Autores: Sivan Arber Raviv, Mohammed Alyan, Egor Egorov, Agam Zano, Moshit Yaskin Harush, Calvin Pieters, Hila Korach-Rechtman, Adi Saadya, Galoz Kaneti, Igor Nudelman, Shai Farkash, Ofri Doppelt Flikshtain, Lucy N Mekies, Lilach Koren, Yoav Gal, Ella Dor, Janna Shainsky, Jeny Shklover, Yochai Adir, Avi Schroeder
Publicado en: Journal of Controlled Release, Edición 346, 2022, Página(s) 421-433, ISSN 2352-3409
Editor: Elsevier BV
DOI: 10.1016/j.jconrel.2022.03.028

Three-dimensional localization microscopy in live flowing cells

Autores: Lucien E. Weiss; Yael Shalev Ezra; Sarah Goldberg; Boris Ferdman; Boris Ferdman; Omer Adir; Avi Schroeder; Onit Alalouf; Yoav Shechtman
Publicado en: Three-dimensional localization microscopy in live flowing cells, Edición 15(6), 2020, Página(s) 500–506, ISSN 1748-3387
Editor: Nature Publishing Group
DOI: 10.1038/s41565-020-0662-0

Robotics, microfluidics, nanotechnology and AI in the synthesis and evaluation of liposomes and polymeric drug delivery systems

Autores: Egor Egorov, Calvin Pieters, Hila Korach-Rechtman, Jeny Shklover, Avi Schroeder
Publicado en: Drug Delivery and Translational Research, Edición 11/2, 2021, Página(s) 345-352, ISSN 2190-393X
Editor: Springer Pub. Co.,
DOI: 10.1007/s13346-021-00929-2

A Simple and Rapid Method for Preparing a Cell-Free Bacterial Lysate for Protein Synthesis

Autores: Nitzan Krinsky, Maya Kaduri, Janna Shainsky-Roitman, Mor Goldfeder, Eran Ivanir, Itai Benhar, Yuval Shoham, Avi Schroeder
Publicado en: PLOS ONE, Edición 11/10, 2016, Página(s) e0165137, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0165137

Nanoparticles target early-stage breast cancer metastasis in vivo

Autores: Evgeniya Goldman, Assaf Zinger, Dana da Silva, Zvi Yaari, Ashima Kajal, Dikla Vardi-Oknin, Mor Goldfeder, Josh E. Schroeder, Janna Shainsky-Roitman, Dov Hershkovitz, Avi Schroeder
Publicado en: Nanotechnology, Edición 28/43, 2017, Página(s) 43LT01, ISSN 0957-4484
Editor: Institute of Physics Publishing
DOI: 10.1088/1361-6528/aa8a3d

Theranostic barcoded nanoparticles for personalized cancer medicine

Autores: Zvi Yaari, Dana da Silva, Assaf Zinger, Evgeniya Goldman, Ashima Kajal, Rafi Tshuva, Efrat Barak, Nitsan Dahan, Dov Hershkovitz, Mor Goldfeder, Janna Shainsky Roitman, Avi Schroeder
Publicado en: Nature Communications, Edición 7, 2016, Página(s) 13325, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/ncomms13325

Synthetic Cells Synthesize Therapeutic Proteins inside Tumors

Autores: Nitzan Krinsky, Maya Kaduri, Assaf Zinger, Janna Shainsky-Roitman, Mor Goldfeder, Itai Benhar, Dov Hershkovitz, Avi Schroeder
Publicado en: Advanced Healthcare Materials, Edición 7/9, 2018, Página(s) 1701163, ISSN 2192-2640
Editor: John Wiley and Sons Ltd
DOI: 10.1002/adhm.201701163

Biocompatibility, biodegradation and excretion of polylactic acid (PLA) in medical implants and theranostic systems

Autores: Dana da Silva, Maya Kaduri, Maria Poley, Omer Adir, Nitzan Krinsky, Janna Shainsky-Roitman, Avi Schroeder
Publicado en: Chemical Engineering Journal, Edición 340, 2018, Página(s) 9-14, ISSN 1385-8947
Editor: Elsevier BV
DOI: 10.1016/j.cej.2018.01.010

Sodium bicarbonate nanoparticles modulate the tumor pH and enhance the cellular uptake of doxorubicin

Autores: Hanan Abumanhal-Masarweh, Lilach Koren, Assaf Zinger, Zvi Yaari, Nitzan Krinsky, Galoz Kaneti, Nitsan Dahan, Yael Lupu-Haber, Edith Suss-Toby, Esther Weiss-Messer, Michal Schlesinger-Laufer, Janna Shainsky-Roitman, Avi Schroeder
Publicado en: Journal of Controlled Release, Edición 296, 2019, Página(s) 1-13, ISSN 0168-3659
Editor: Elsevier BV
DOI: 10.1016/j.jconrel.2019.01.004

Proteolytic Nanoparticles Replace a Surgical Blade by Controllably Remodeling the Oral Connective Tissue

Autores: Assaf Zinger, Omer Adir, Matan Alper, Assaf Simon, Maria Poley, Chen Tzror, Zvi Yaari, Majd Krayem, Shira Kasten, Guy Nawy, Avishai Herman, Yael Nir, Sharon Akrish, Tidhar Klein, Janna Shainsky-Roitman, Dov Hershkovitz, Avi Schroeder
Publicado en: ACS Nano, Edición 12/2, 2018, Página(s) 1482-1490, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.7b07983

Autonomous bacterial nanoswimmers target cancer

Autores: Nour Zoaby, Janna Shainsky-Roitman, Samah Badarneh, Hanan Abumanhal, Alex Leshansky, Sima Yaron, Avi Schroeder
Publicado en: Journal of Controlled Release, Edición 257, 2017, Página(s) 68-75, ISSN 0168-3659
Editor: Elsevier BV
DOI: 10.1016/j.jconrel.2016.10.006

Tailoring the lipid composition of nanoparticles modulates their cellular uptake and affects the viability of triple negative breast cancer cells

Autores: Hanan Abumanhal-Masarweh, Dana da Silva, Maria Poley, Assaf Zinger, Evgenya Goldman, Nitzan Krinsky, Ron Kleiner, Gal Shenbach, Josh E. Schroeder, Jeny Shklover, Janna Shainsky-Roitman, Avi Schroeder
Publicado en: Journal of Controlled Release, Edición 307, 2019, Página(s) 331-341, ISSN 0168-3659
Editor: Elsevier BV
DOI: 10.1016/j.jconrel.2019.06.025

Integrating Artificial Intelligence and Nanotechnology for Precision Cancer Medicine

Autores: Omer Adir, Maria Poley, Gal Chen, Sahar Froim, Nitzan Krinsky, Jeny Shklover, Janna Shainsky‐Roitman, Twan Lammers, Avi Schroeder
Publicado en: Advanced Materials, Edición 32/13, 2019, Página(s) 1901989, ISSN 0935-9648
Editor: United Nations Industrial Developement Organization
DOI: 10.1002/adma.201901989

Derechos de propiedad intelectual

Patent (5)

COLLAGENASE LOADED LIPOSOMES FOR ENHANCING DRUG DELIVERY

Número de solicitud/publicación: 19 743889
Fecha: 2019-01-23
Solicitante(s): TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY

Delivery system comprising a proteolytic enzyme or effector thereof for use in a method for oral treatment and uses thereof AD Schroeder, AY ZINGER, A HERMAN

Número de solicitud/publicación: US 10183064B2
Fecha: 2015-03-19
Solicitante(s): TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY

Methods and kits for cell-free transcription and translation. AV Schroeder, J Shainsky-roitman, M Goldfeder, N Krinsky, Y Shoham

Número de solicitud/publicación: US 20170198326A1
Fecha: 2015-07-08
Solicitante(s): TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY

HYBRID MUCO-ADHESIVE DELIVERY SYSTEMS AND USE THEREOF

Número de solicitud/publicación: 17 814897
Fecha: 2017-06-21
Solicitante(s): TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY

Compositions and methods for therapeutics prescreening. A Schroeder, Z Yaari

Número de solicitud/publicación: US 20170233823A1
Fecha: 2015-08-13
Solicitante(s): TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY