Next-Generation Personalized Diagnostic Nanotechnologies for Predicting Response to Cancer Medicine

Informazioni relative al progetto

BARCODE DIAGNOSTICS

ID dell’accordo di sovvenzione: 680242

DOI

10.3030/680242

Progetto chiuso

Data della firma CE 29 Marzo 2016

Data di avvio 1 Aprile 2016

Data di completamento 31 Marzo 2022

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 499 250,00

Contributo UE

€ 1 499 250,00

Coordinato da

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Israel

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (18)

Collagenase Nanoparticles Enhance the Penetration of Drugs into Pancreatic Tumors

Autori: Assaf Zinger, Lilach Koren, Omer Adir, Maria Poley, Mohammed Alyan, Zvi Yaari, Nadav Noor, Nitzan Krinsky, Assaf Simon, Hadas Gibori, Majd Krayem, Yelena Mumblat, Shira Kasten, Sivan Ofir, Eran Fridman, Neta Milman, Michael M Lübtow, Lior Liba, Jeny Shklover, Janna Shainsky-Roitman, Yoav Binenbaum, Dov Hershkovitz, Ziv Gil, Tal Dvir, Robert Luxenhofer, Ronit Satchi-Fainaro, Avi Schroeder
Pubblicato in: Collagenase Nanoparticles Enhance the Penetration of Drugs into Pancreatic Tumors, Numero 22;13(10), 2019, Pagina/e 11008-11021, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.9b02395

Synthetic Cells with Self-Activating Optogenetic Proteins Communicate with Natural Cells

Autori: Omer Adir, Mia R. Albalak, Ravit Abel, Lucien E. Weiss, Gal Chen, Amit Gruber, Oskar Staufer, Yaniv Kurman, Ido Kaminer, Jeny Shklover, Janna Shainsky-Roitman, Ilia Platzman, Lior Gepstein, Yoav Shechtman, Benjamin Horwitz, Avi Schroeder
Pubblicato in: Nature Communications, Numero 28;13(1), 2022, Pagina/e 2328, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41467-022-29871-8

Preparing Protein Producing Synthetic Cells using Cell Free Bacterial Extracts, Liposomes and Emulsion Transfer

Autori: Omer Adir, Noga Sharf-Pauker, Gal Chen, Maya Kaduri, Nitzan Krinsky, Janna Shainsky-Roitman, Jeny Shklover, Avi Schroeder
Pubblicato in: JoVE (Journal of Visualized Experiments), 2020, ISSN 1940-087X
Editore: MYJoVE Corporation
DOI: 10.3791/60829

Nanoparticles Accumulate in the Female Reproductive System during Ovulation Affecting Cancer Treatment and Fertility

Autori: Maria Poley, Patricia Mora-Raimundo, Yael Shammai, Maya Kaduri, Lilach Koren, Omer Adir, Jeny Shklover, Janna Shainsky-Roitman, Srinivas Ramishetti, Francis Man, Rafael T. M. de Rosales, Assaf Zinger, Dan Peer, Irit Ben-Aharon, Avi Schroeder
Pubblicato in: ACS Nano, Numero 16/4, 2022, Pagina/e 5246-5257, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.1c07237

Targeting neurons in the tumor microenvironment with bupivacaine nanoparticles reduces breast cancer progression and metastases

Autori: Maya Kaduri, Mor Sela, Shaked Kagan, Maria Poley, Hanan Abumanhal-Masarweh, Patricia Mora-Raimundo, Alberto Ouro, Nitsan Dahan, Dov Hershkovitz, Jeny Shklover, Janna Shainsky-Roitman, Yosef Buganim, Avi Schroeder
Pubblicato in: Science Advances, Numero 7/41, 2021, ISSN 0036-8075
Editore: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abj5435

Lung targeted liposomes for treating ARDS

Autori: Sivan Arber Raviv, Mohammed Alyan, Egor Egorov, Agam Zano, Moshit Yaskin Harush, Calvin Pieters, Hila Korach-Rechtman, Adi Saadya, Galoz Kaneti, Igor Nudelman, Shai Farkash, Ofri Doppelt Flikshtain, Lucy N Mekies, Lilach Koren, Yoav Gal, Ella Dor, Janna Shainsky, Jeny Shklover, Yochai Adir, Avi Schroeder
Pubblicato in: Journal of Controlled Release, Numero 346, 2022, Pagina/e 421-433, ISSN 2352-3409
Editore: Elsevier BV
DOI: 10.1016/j.jconrel.2022.03.028

Three-dimensional localization microscopy in live flowing cells

Autori: Lucien E. Weiss; Yael Shalev Ezra; Sarah Goldberg; Boris Ferdman; Boris Ferdman; Omer Adir; Avi Schroeder; Onit Alalouf; Yoav Shechtman
Pubblicato in: Three-dimensional localization microscopy in live flowing cells, Numero 15(6), 2020, Pagina/e 500–506, ISSN 1748-3387
Editore: Nature Publishing Group
DOI: 10.1038/s41565-020-0662-0

Robotics, microfluidics, nanotechnology and AI in the synthesis and evaluation of liposomes and polymeric drug delivery systems

Autori: Egor Egorov, Calvin Pieters, Hila Korach-Rechtman, Jeny Shklover, Avi Schroeder
Pubblicato in: Drug Delivery and Translational Research, Numero 11/2, 2021, Pagina/e 345-352, ISSN 2190-393X
Editore: Springer Pub. Co.,
DOI: 10.1007/s13346-021-00929-2

A Simple and Rapid Method for Preparing a Cell-Free Bacterial Lysate for Protein Synthesis

Autori: Nitzan Krinsky, Maya Kaduri, Janna Shainsky-Roitman, Mor Goldfeder, Eran Ivanir, Itai Benhar, Yuval Shoham, Avi Schroeder
Pubblicato in: PLOS ONE, Numero 11/10, 2016, Pagina/e e0165137, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0165137

Nanoparticles target early-stage breast cancer metastasis in vivo

Autori: Evgeniya Goldman, Assaf Zinger, Dana da Silva, Zvi Yaari, Ashima Kajal, Dikla Vardi-Oknin, Mor Goldfeder, Josh E. Schroeder, Janna Shainsky-Roitman, Dov Hershkovitz, Avi Schroeder
Pubblicato in: Nanotechnology, Numero 28/43, 2017, Pagina/e 43LT01, ISSN 0957-4484
Editore: Institute of Physics Publishing
DOI: 10.1088/1361-6528/aa8a3d

Theranostic barcoded nanoparticles for personalized cancer medicine

Autori: Zvi Yaari, Dana da Silva, Assaf Zinger, Evgeniya Goldman, Ashima Kajal, Rafi Tshuva, Efrat Barak, Nitsan Dahan, Dov Hershkovitz, Mor Goldfeder, Janna Shainsky Roitman, Avi Schroeder
Pubblicato in: Nature Communications, Numero 7, 2016, Pagina/e 13325, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/ncomms13325

Synthetic Cells Synthesize Therapeutic Proteins inside Tumors

Autori: Nitzan Krinsky, Maya Kaduri, Assaf Zinger, Janna Shainsky-Roitman, Mor Goldfeder, Itai Benhar, Dov Hershkovitz, Avi Schroeder
Pubblicato in: Advanced Healthcare Materials, Numero 7/9, 2018, Pagina/e 1701163, ISSN 2192-2640
Editore: John Wiley and Sons Ltd
DOI: 10.1002/adhm.201701163

Biocompatibility, biodegradation and excretion of polylactic acid (PLA) in medical implants and theranostic systems

Autori: Dana da Silva, Maya Kaduri, Maria Poley, Omer Adir, Nitzan Krinsky, Janna Shainsky-Roitman, Avi Schroeder
Pubblicato in: Chemical Engineering Journal, Numero 340, 2018, Pagina/e 9-14, ISSN 1385-8947
Editore: Elsevier BV
DOI: 10.1016/j.cej.2018.01.010

Sodium bicarbonate nanoparticles modulate the tumor pH and enhance the cellular uptake of doxorubicin

Autori: Hanan Abumanhal-Masarweh, Lilach Koren, Assaf Zinger, Zvi Yaari, Nitzan Krinsky, Galoz Kaneti, Nitsan Dahan, Yael Lupu-Haber, Edith Suss-Toby, Esther Weiss-Messer, Michal Schlesinger-Laufer, Janna Shainsky-Roitman, Avi Schroeder
Pubblicato in: Journal of Controlled Release, Numero 296, 2019, Pagina/e 1-13, ISSN 0168-3659
Editore: Elsevier BV
DOI: 10.1016/j.jconrel.2019.01.004

Proteolytic Nanoparticles Replace a Surgical Blade by Controllably Remodeling the Oral Connective Tissue

Autori: Assaf Zinger, Omer Adir, Matan Alper, Assaf Simon, Maria Poley, Chen Tzror, Zvi Yaari, Majd Krayem, Shira Kasten, Guy Nawy, Avishai Herman, Yael Nir, Sharon Akrish, Tidhar Klein, Janna Shainsky-Roitman, Dov Hershkovitz, Avi Schroeder
Pubblicato in: ACS Nano, Numero 12/2, 2018, Pagina/e 1482-1490, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.7b07983

Autonomous bacterial nanoswimmers target cancer

Autori: Nour Zoaby, Janna Shainsky-Roitman, Samah Badarneh, Hanan Abumanhal, Alex Leshansky, Sima Yaron, Avi Schroeder
Pubblicato in: Journal of Controlled Release, Numero 257, 2017, Pagina/e 68-75, ISSN 0168-3659
Editore: Elsevier BV
DOI: 10.1016/j.jconrel.2016.10.006

Tailoring the lipid composition of nanoparticles modulates their cellular uptake and affects the viability of triple negative breast cancer cells

Autori: Hanan Abumanhal-Masarweh, Dana da Silva, Maria Poley, Assaf Zinger, Evgenya Goldman, Nitzan Krinsky, Ron Kleiner, Gal Shenbach, Josh E. Schroeder, Jeny Shklover, Janna Shainsky-Roitman, Avi Schroeder
Pubblicato in: Journal of Controlled Release, Numero 307, 2019, Pagina/e 331-341, ISSN 0168-3659
Editore: Elsevier BV
DOI: 10.1016/j.jconrel.2019.06.025

Integrating Artificial Intelligence and Nanotechnology for Precision Cancer Medicine

Autori: Omer Adir, Maria Poley, Gal Chen, Sahar Froim, Nitzan Krinsky, Jeny Shklover, Janna Shainsky‐Roitman, Twan Lammers, Avi Schroeder
Pubblicato in: Advanced Materials, Numero 32/13, 2019, Pagina/e 1901989, ISSN 0935-9648
Editore: United Nations Industrial Developement Organization
DOI: 10.1002/adma.201901989

Diritti di proprietà intellettuale

Patent (5)

COLLAGENASE LOADED LIPOSOMES FOR ENHANCING DRUG DELIVERY

Numero candidatura/pubblicazione: 19 743889
Data: 2019-01-23
Candidato/i: TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY

Delivery system comprising a proteolytic enzyme or effector thereof for use in a method for oral treatment and uses thereof AD Schroeder, AY ZINGER, A HERMAN

Numero candidatura/pubblicazione: US 10183064B2
Data: 2015-03-19
Candidato/i: TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY

Methods and kits for cell-free transcription and translation. AV Schroeder, J Shainsky-roitman, M Goldfeder, N Krinsky, Y Shoham

Numero candidatura/pubblicazione: US 20170198326A1
Data: 2015-07-08
Candidato/i: TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY

HYBRID MUCO-ADHESIVE DELIVERY SYSTEMS AND USE THEREOF

Numero candidatura/pubblicazione: 17 814897
Data: 2017-06-21
Candidato/i: TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY

Compositions and methods for therapeutics prescreening. A Schroeder, Z Yaari

Numero candidatura/pubblicazione: US 20170233823A1
Data: 2015-08-13
Candidato/i: TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY