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European HIV Vaccine Alliance (EHVA): a EU platform for the discovery and evaluation of novel prophylactic and therapeutic vaccine candidates

Objective

Many HIV vaccine concepts and several efficacy trials have been conducted in the prophylactic and therapeutic fields with limited success. There is an urgent need to develop better vaccines and tools predictive of immunogenicity and of correlates of protection at early stage of vaccine development to mitigate the risks of failure. To address these complex and challenging scientific issues, the European HIV Vaccine Alliance (EHVA) program will develop a Multidisciplinary Vaccine Platform (MVP) in the fields of prophylactic and therapeutic HIV vaccines. The Specific Objectives of the MVP are to build up: 1.Discovery Platform with the goal of generating novel vaccine candidates inducing potent neutralizing and non-neutralizing antibody responses and T-cell responses, 2. Immune Profiling Platform with the goal of ranking novel and existing (benchmark) vaccine candidates on the basis of the immune profile, 3. Data Management/Integration/Down-Selection Platform, with the goal of providing statistical tools for the analysis and interpretation of complex data and algorithms for the efficient selection of vaccines, and 4. Clinical Trials Platform with the goal of accelerating the clinical development of novel vaccines and the early prediction of vaccine failure. EHVA project has developed a global and innovative strategy which includes: a) the multidisciplinary expertise involving immunologists, virologists, structural biology experts, statisticians and computational scientists and clinicians; b) the most innovative technologies to profile immune response and virus reservoir; c) the access to large cohort studies bringing together top European clinical scientists/centres in the fields of prophylactic and therapeutic vaccines, d) the access to a panel of experimental HIV vaccines under clinical development that will be used as benchmark, and e) the liaison to a number of African leading scientists/programs which will foster the testing of future EHVA vaccines through EDCTP

Call for proposal

H2020-PHC-2014-2015

See other projects for this call

Sub call

H2020-PHC-2015-single-stage_RTD

Coordinator

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
Net EU contribution
€ 1 800 938,02
Address
Rue De Tolbiac 101
75654 Paris
France
Activity type
Research Organisations
Non-EU contribution
€ 3,24

Participants (46)

Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

CHU HOPITAUX DE BORDEAUX
France
Net EU contribution
€ 146 512,50
Address
Rue Dubernat 12
33404 Talence
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Region
Nouvelle-Aquitaine Aquitaine Gironde
 
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

UNIVERSITE DE BORDEAUX
France
Net EU contribution
€ 27 887,50
Address
Place Pey Berland 35
33000 Bordeaux
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

UNIVERSITE DE STRASBOURG
France
Net EU contribution
€ 48 500,00
Address
Rue Blaise Pascal 4
67081 Strasbourg
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS
Switzerland
Net EU contribution
€ 0,00
Address
Rue Du Bugnon 21
1011 Lausanne
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Non-EU contribution
€ 2 310 845,00
Region
Schweiz/Suisse/Svizzera Région lémanique Vaud
SANOFI PASTEUR SA
France
Net EU contribution
€ 50 000,00
Address
14 Espace Henry Vallee
69007 Lyon
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER
Spain
Net EU contribution
€ 812 604,88
Address
Calle Rossello 149 Puerta Bjs
08036 Barcelona
Activity type
Other
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

HOSPITAL CLINIC DE BARCELONA
Spain
Net EU contribution
€ 102 433,88
Address
Calle Villarroel 170
08036 Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,00
HEINRICH-PETTE INSTITUT LEIBNIZ INSTITUT FUER EXPERIMENTELLE VIROLOGIE
Germany
Net EU contribution
€ 992 500,00
Address
Martinistrasse 52
20251 Hamburg
Activity type
Research Organisations
Non-EU contribution
€ 0,00
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
Net EU contribution
€ 916 601,15
Address
South Kensington Campus Exhibition Road
SW7 2AZ London
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
ISTITUTO SUPERIORE DI SANITA
Italy
Net EU contribution
€ 537 250,00
Address
Viale Regina Elena 299
00161 Roma
Activity type
Research Organisations
Non-EU contribution
€ 0,00
UNIVERSITAET REGENSBURG
Germany
Net EU contribution
€ 933 750,00
Address
Universitatsstrasse 31
93053 Regensburg
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Region
Bayern Oberpfalz Regensburg, Kreisfreie Stadt
KAROLINSKA INSTITUTET
Sweden
Net EU contribution
€ 508 246,00
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITAT ZURICH
Switzerland
Net EU contribution
€ 0,00
Address
Ramistrasse 71
8006 Zurich
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 649 945,00
FONDAZIONE PER L'ISTITUTO DI RICERCA IN BIOMEDICINA
Switzerland
Net EU contribution
€ 0,00
Address
Via Francesco Chiesa 5
6500 Bellinzona
Activity type
Research Organisations
Non-EU contribution
€ 680 875,00
UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF
Germany
Net EU contribution
€ 616 500,00
Address
Martinistrasse 52
20251 Hamburg
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Region
Baden-Württemberg Stuttgart Stuttgart, Stadtkreis
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
Net EU contribution
€ 564 977,50
Address
Wellington Square University Offices
OX1 2JD Oxford
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
UNIVERSITE GRENOBLE ALPES
France
Net EU contribution
€ 567 637,50
Address
621 Avenue Centrale
38058 Grenoble
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Region
Auvergne-Rhône-Alpes Rhône-Alpes Isère
 
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
Netherlands
Net EU contribution
€ 269 375,00
Address
Meibergdreef 15
1105AZ Amsterdam
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

STICHTING AMSTERDAM INSTITUTE FOR GLOBAL HEALTH AND DEVELOPMENT
Netherlands
Net EU contribution
€ 145 562,50
Address
Paasheuvelweg 25 Tower C4
1105 BP Amsterdam
Activity type
Research Organisations
Non-EU contribution
€ 0,00
STICHTING BIOMEDICAL PRIMATE RESEARCH CENTER
Netherlands
Net EU contribution
€ 1 000 017,50
Address
Lange Kleiweg 161
2288 GJ Rijswijk Zh
Activity type
Research Organisations
Non-EU contribution
€ 0,00
Region
West-Nederland Zuid-Holland Agglomeratie ’s-Gravenhage
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany
Net EU contribution
€ 365 000,00
Address
Geschwister Scholl Platz 1
80539 Muenchen
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
MEDIZINISCHE UNIVERSITAT INNSBRUCK
Austria
Net EU contribution
€ 515 000,00
Address
Christoph Probst Platz 1
6020 Innsbruck
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain
Net EU contribution
€ 414 973,75
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
Non-EU contribution
€ 0,00
UNIVERSITE DE LAUSANNE
Switzerland
Net EU contribution
€ 0,00
Address
Quartier Unil-centre Bâtiment Unicentre
1015 Lausanne
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 1 198 750,00
Region
Schweiz/Suisse/Svizzera Région lémanique Vaud
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands
Net EU contribution
€ 310 000,00
Address
Dr Molewaterplein 40
3015 GD Rotterdam
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
STICHTING INTERNATIONAL AIDS VACCINE INITIATIVE THE NETHERLANDS
Netherlands
Net EU contribution
€ 93 748,75
Address
Van Diemenstraat 20, 200 Unit 48
1013 NH Amsterdam
Activity type
Other
Non-EU contribution
€ 0,00
Region
West-Nederland Noord-Holland Groot-Amsterdam
 
FIT BIOTECH OY

Participation ended

Finland
Net EU contribution
€ 965 183,51
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Address
Biokatu 8
33520 Tampere
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
EUROVACC FOUNDATION
Switzerland
Net EU contribution
€ 0,00
Address
Place Saint-francois 1 Etude Kellerhals Carrard
1003 Lausanne
Activity type
Other
Non-EU contribution
€ 320 475,00
Region
Schweiz/Suisse/Svizzera Région lémanique Vaud
FRED HUTCHINSON CANCER RESEARCH CENTER NON PROFIT CORPORATION
United States
Net EU contribution
€ 350 000,00
Address
Fairview Avenue 1100
98109 Seattle Wa
Activity type
Research Organisations
Non-EU contribution
€ 0,00
COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
France
Net EU contribution
€ 707 842,50
Address
Rue Leblanc 25
75015 Paris 15
Activity type
Research Organisations
Non-EU contribution
€ 0,00
UNIVERSITAET BERN
Switzerland
Net EU contribution
€ 0,00
Address
Hochschulstrasse 6
3012 Bern
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 786 181,25
Region
Schweiz/Suisse/Svizzera Espace Mittelland Bern / Berne
JANSSEN VACCINES & PREVENTION BV
Netherlands
Net EU contribution
€ 34 845,00
Address
Archimedesweg 4
2333 CN Leiden
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,01
Region
West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek
UGANDA NATIONAL HEALTH RESEARCH ORGANISATION
Uganda
Net EU contribution
€ 24 985,00
Address
Berkeley Lane Plot 2
465 Entebbe
Activity type
Research Organisations
Non-EU contribution
€ 0,00
NATIONAL INSTITUTE FOR MEDICAL RESEARCH
Tanzania
Net EU contribution
€ 15 000,00
Address
Sokoine Luthuli Drive Ocean Road
255 Dar Es Salaam
Activity type
Research Organisations
Non-EU contribution
€ 0,00
Instituto Nacional de Saúde
Mozambique
Net EU contribution
€ 15 000,00
Address
Avenida Eduardo Mondlane 1008
Maputo
Activity type
Research Organisations
Non-EU contribution
€ 0,00
ASSOCIATION PAC-CI
Côte d’Ivoire
Net EU contribution
€ 15 000,00
Address
Chu De Trechville 18 Usac Extension 18
Abidjan
Activity type
Research Organisations
Non-EU contribution
€ 0,00
UNIVERSITY COLLEGE LONDON
United Kingdom
Net EU contribution
€ 2 514 226,25
Address
Gower Street
WC1E 6BT London
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Region
London Inner London — West Camden and City of London
THE UNIVERSITY OF LIVERPOOL
United Kingdom
Net EU contribution
€ 300 000,00
Address
Brownlow Hill 765 Foundation Building
L69 7ZX Liverpool
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
THE GENERAL HOSPITAL CORPORATION
United States
Net EU contribution
€ 100 000,00
Address
Fruit Street 55
02114 Boston Ma
Activity type
Other
Non-EU contribution
€ 0,00
VRIJE UNIVERSITEIT BRUSSEL
Belgium
Net EU contribution
€ 149 950,00
Address
Pleinlaan 2
1050 Brussel
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Region
Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest
ISTITUTO NAZIONALE PER LE MALATTIE INFETTIVE LAZZARO SPALLANZANI-ISTITUTO DI RICOVERO E CURA A CARATTERE SCIENTIFICO
Italy
Net EU contribution
€ 249 963,75
Address
Via Portuense, 292
00149 Roma
Activity type
Research Organisations
Non-EU contribution
€ 0,00
EUROPEAN AIDS TREATMENT GROUP EV
Germany
Net EU contribution
€ 50 000,00
Address
Mettmanner Strasse 24-26
40233 Dusseldorf
Activity type
Other
Non-EU contribution
€ 0,00
Region
Nordrhein-Westfalen Düsseldorf Düsseldorf, Kreisfreie Stadt
INSERM TRANSFERT SA
France
Net EU contribution
€ 580 710,00
Address
Rue Watt 7
75013 Paris
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
INTERNATIONAL AIDS VACCINE INITIATIVE INC
United States
Net EU contribution
€ 3 858 898,20
Address
125 Broad Street, 9Th Floor
10004 New York
Activity type
Research Organisations
Non-EU contribution
€ 0,00
CHELSEA AND WESTMINSTER HOSPITAL NHS FOUNDATION TRUST
United Kingdom
Net EU contribution
€ 516 901,11
Address
369 Fulham Road
SW10 9NH London
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Non-EU contribution
€ 0,00
VACCINE FORMULATION INSTITUTE(CH)LTD
Switzerland
Net EU contribution
€ 0,00
Address
Chemin Des Aulx 14
1228 Plan Les Ouates
Activity type
Other
Non-EU contribution
€ 89 100,00
Region
Schweiz/Suisse/Svizzera Région lémanique Genève