Publications Peer reviewed articles (28) The role of neutrophils in trained immunity Author(s): Lydia Kalafati, Aikaterini Hatzioannou, George Hajishengallis, Triantafyllos Chavakis Published in: Immunological Reviews, 2022, ISSN 0105-2896 Publisher: Blackwell Publishing Inc. DOI: 10.1111/imr.13142 The RNA binding protein human antigen R is a gatekeeper of liver homeostasis Author(s): Pallavi Subramanian, Sofia Gargani, Alessandra Palladini, Margarita Chatzimike, Michal Grzybek, Mirko Peitzsch, Anastasios D. Papanastasiou, Iryna Pyrina, Vasileios Ntafis, Bettina Gercken, Mathias Lesche, Andreas Petzold, Anupam Sinha, Marina Nati, Veera Raghavan Thangapandi, Ioannis Kourtzelis, Margarita Andreadou, Anke Witt, Andreas Dahl, Ralph Burkhardt, Robert Haase, António Miguel de Jesus Published in: Hepatology, Issue Volume75, Issue4, 2022, Page(s) Pages 881-897, ISSN 0270-9139 Publisher: John Wiley & Sons Inc. DOI: 10.1002/hep.32153 The DEL-1/β3 integrin axis promotes regulatory T cell responses during inflammation resolution Author(s): Xiaofei Li, Alessandra Colamatteo, Lydia Kalafati, Tetsuhiro Kajikawa, Hui Wang, Jong-Hyung Lim, Khalil Bdeir, Kyoung-Jin Chung, Xiang Yu, Clorinda Fusco, Antonio Porcellini, Salvatore De Simone, Giuseppe Matarese, Triantafyllos Chavakis, Veronica De Rosa, George Hajishengallis Published in: Journal of Clinical Investigation, Issue 130/12, 2020, Page(s) 6261-6277, ISSN 0021-9738 Publisher: American Society for Clinical Investigation DOI: 10.1172/jci137530 Hepatic Senescence Accompanies the Development of NAFLD in Non-Aged Mice Independently of Obesity Author(s): Ioannis I. Moustakas, Angeliki Katsarou, Aigli-Ioanna Legaki, Iryna Pyrina, Konstantinos Ntostoglou, Alkistis-Maria Papatheodoridi, Bettina Gercken, Ioannis S. Pateras, Vassilis G. Gorgoulis, Michael Koutsilieris, Triantafyllos Chavakis, Antonios Chatzigeorgiou Published in: International Journal of Molecular Sciences, Issue 22/7, 2021, Page(s) 3446, ISSN 1422-0067 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms22073446 DHEA Inhibits Leukocyte Recruitment through Regulation of the Integrin Antagonist DEL-1 Author(s): Athanasios Ziogas, Tomoki Maekawa, Johannes R. Wiessner, Thi Trang Le, David Sprott, Maria Troullinaki, Ales Neuwirth, Vasiliki Anastasopoulou, Sylvia Grossklaus, Kyoung-Jin Chung, Markus Sperandio, Triantafyllos Chavakis, George Hajishengallis, Vasileia Ismini Alexaki Published in: The Journal of Immunology, Issue 204/5, 2020, Page(s) 1214-1224, ISSN 0022-1767 Publisher: American Association of Immunologists DOI: 10.4049/jimmunol.1900746 BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils Author(s): Simone J.C.F.M. Moorlag, Yessica Alina Rodriguez-Rosales, Joshua Gillard, Stephanie Fanucchi, Kate Theunissen, Boris Novakovic, Cynthia M. de Bont, Yutaka Negishi, Ezio T. Fok, Lydia Kalafati, Panayotis Verginis, Vera P. Mourits, Valerie A.C.M. Koeken, L. Charlotte J. de Bree, Ger J.M. Pruijn, Craig Fenwick, Reinout van Crevel, Leo A.B. Joosten, Irma Joosten, Hans Koenen, Musa M. Mhlanga, Dimitri Published in: Cell Reports, Issue 33/7, 2020, Page(s) 108387, ISSN 2211-1247 Publisher: Cell Press DOI: 10.1016/j.celrep.2020.108387 Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity Author(s): Lydia Kalafati, Ioannis Kourtzelis, Jonas Schulte-Schrepping, Xiaofei Li, Aikaterini Hatzioannou, Tatyana Grinenko, Eman Hagag, Anupam Sinha, Canan Has, Sevina Dietz, Antonio Miguel de Jesus Domingues, Marina Nati, Sundary Sormendi, Ales Neuwirth, Antonios Chatzigeorgiou, Athanasios Ziogas, Mathias Lesche, Andreas Dahl, Ian Henry, Pallavi Subramanian, Ben Wielockx, Peter Murray, Peter Mirtschink, Published in: Cell, Issue 183/3, 2020, Page(s) 771-785.e12, ISSN 0092-8674 Publisher: Cell Press DOI: 10.1016/j.cell.2020.09.058 Erythromycin inhibits neutrophilic inflammation and mucosal disease by upregulating DEL-1 Author(s): Tomoki Maekawa, Hikaru Tamura, Hisanori Domon, Takumi Hiyoshi, Toshihito Isono, Daisuke Yonezawa, Naoki Hayashi, Naoki Takahashi, Koichi Tabeta, Takeyasu Maeda, Masataka Oda, Athanasios Ziogas, Vasileia Ismini Alexaki, Triantafyllos Chavakis, Yutaka Terao, George Hajishengallis Published in: JCI Insight, Issue 5/15, 2020, ISSN 2379-3708 Publisher: American Society for Clinical Investigation DOI: 10.1172/jci.insight.136706 Immunometabolism: Where Immunology and Metabolism Meet Author(s): Triantafyllos Chavakis Published in: Journal of Innate Immunity, Issue 2022, Vol.14, 2022, Page(s) 1–3, ISSN 1662-811X Publisher: Karger AG DOI: 10.1159/000521305 Regulation of the Bone Marrow Niche by Inflammation Author(s): Ioannis Mitroulis, Lydia Kalafati, Martin Bornhäuser, George Hajishengallis, Triantafyllos Chavakis Published in: Frontiers in Immunology, Issue 11, 2020, ISSN 1664-3224 Publisher: Roi Gazit DOI: 10.3389/fimmu.2020.01540 Defining trained immunity and its role in health and disease Author(s): Mihai G. Netea, Jorge Domínguez-Andrés, Luis B. Barreiro, Triantafyllos Chavakis, Maziar Divangahi, Elaine Fuchs, Leo A. B. Joosten, Jos W. M. van der Meer, Musa M. Mhlanga, Willem J. M. Mulder, Niels P. Riksen, Andreas Schlitzer, Joachim L. Schultze, Christine Stabell Benn, Joseph C. Sun, Ramnik J. Xavier, Eicke Latz Published in: Nature Reviews Immunology, Issue 20/6, 2020, Page(s) 375-388, ISSN 1474-1733 Publisher: Nature Publishing Group DOI: 10.1038/s41577-020-0285-6 Secreted protein Del-1 regulates myelopoiesis in the hematopoietic stem cell niche Author(s): Ioannis Mitroulis, Lan-Sun Chen, Rashim Pal Singh, Ioannis Kourtzelis, Matina Economopoulou, Tetsuhiro Kajikawa, Maria Troullinaki, Athanasios Ziogas, Klara Ruppova, Kavita Hosur, Tomoki Maekawa, Baomei Wang, Pallavi Subramanian, Torsten Tonn, Panayotis Verginis, Malte von Bonin, Manja Wobus, Martin Bornhäuser, Tatyana Grinenko, Marianna Di Scala, Andres Hidalgo, Ben Wielockx, George Hajishengall Published in: Journal of Clinical Investigation, Issue 127/10, 2017, Page(s) 3624-3639, ISSN 0021-9738 Publisher: American Society for Clinical Investigation DOI: 10.1172/jci92571 A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity Author(s): Kyoung-Jin Chung, Antonios Chatzigeorgiou, Matina Economopoulou, Ruben Garcia-Martin, Vasileia I Alexaki, Ioannis Mitroulis, Marina Nati, Janine Gebler, Tjalf Ziemssen, Susan E Goelz, Julia Phieler, Jong-Hyung Lim, Katia P Karalis, Thalia Papayannopoulou, Matthias Blüher, George Hajishengallis, Triantafyllos Chavakis Published in: Nature Immunology, Issue 18/6, 2017, Page(s) 654-664, ISSN 1529-2908 Publisher: Nature Publishing Group DOI: 10.1038/ni.3728 Hematopoietic stem cells can differentiate into restricted myeloid progenitors before cell division in mice Author(s): Tatyana Grinenko, Anne Eugster, Lars Thielecke, Beáta Ramasz, Anja Krüger, Sevina Dietz, Ingmar Glauche, Alexander Gerbaulet, Malte von Bonin, Onur Basak, Hans Clevers, Triantafyllos Chavakis, Ben Wielockx Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-018-04188-7 Hematopoietic Stem Cells but Not Multipotent Progenitors Drive Erythropoiesis during Chronic Erythroid Stress in EPO Transgenic Mice Author(s): Rashim Pal Singh, Tatyana Grinenko, Beáta Ramasz, Kristin Franke, Mathias Lesche, Andreas Dahl, Max Gassmann, Triantafyllos Chavakis, Ian Henry, Ben Wielockx Published in: Stem Cell Reports, Issue 10/6, 2018, Page(s) 1908-1919, ISSN 2213-6711 Publisher: Cell Press DOI: 10.1016/j.stemcr.2018.04.012 Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity Author(s): Ioannis Mitroulis, Klara Ruppova, Baomei Wang, Lan-Sun Chen, Michal Grzybek, Tatyana Grinenko, Anne Eugster, Maria Troullinaki, Alessandra Palladini, Ioannis Kourtzelis, Antonios Chatzigeorgiou, Andreas Schlitzer, Marc Beyer, Leo A.B. Joosten, Berend Isermann, Mathias Lesche, Andreas Petzold, Kai Simons, Ian Henry, Andreas Dahl, Joachim L. Schultze, Ben Wielockx, Nicola Zamboni, Peter Mirtschink, Published in: Cell, Issue 172/1-2, 2018, Page(s) 147-161.e12, ISSN 0092-8674 Publisher: Cell Press DOI: 10.1016/j.cell.2017.11.034 Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function Author(s): Thati Madhusudhan, Hongjie Wang, Sanchita Ghosh, Wei Dong, Varun Kumar, Moh'd Mohanad Al-Dabet, Jayakumar Manoharan, Sumra Nazir, Ahmed Elwakiel, Fabian Bock, Shrey Kohli, Andi Marquardt, Ibrahim Sögüt, Khurrum Shahzad, Andreas J. Müller, Charles T. Esmon, Peter P. Nawroth, Jochen Reiser, Triantafyllos Chavakis, Wolfram Ruf, Berend Isermann Published in: Blood, Issue 130/12, 2017, Page(s) 1445-1455, ISSN 0006-4971 Publisher: American Society of Hematology DOI: 10.1182/blood-2017-02-767921 IL-1 Family Cytokine Pathways Underlying NAFLD: Towards New Treatment Strategies Author(s): Andreea-Manuela Mirea, Cees J. Tack, Triantafyllos Chavakis, Leo A.B. Joosten, Erik J.M. Toonen Published in: Trends in Molecular Medicine, Issue 24/5, 2018, Page(s) 458-471, ISSN 1471-4914 Publisher: Elsevier BV DOI: 10.1016/j.molmed.2018.03.005 Endothelial cell-specific overexpression of developmental endothelial locus-1 does not influence atherosclerosis development in ApoE-/- mice Author(s): Marta Prucnal, Bettina Gercken, Matina Economopoulou, George Hajishengallis, Triantafyllos Chavakis, Pallavi Subramanian Published in: Thrombosis and Haemostasis, Issue 117/10, 2017, Page(s) 2003-2005, ISSN 0340-6245 Publisher: Schattauer DOI: 10.1160/th17-03-0160 Comprehensive and quantitative analysis of white and brown adipose tissue by shotgun lipidomics Author(s): Michal Grzybek, Alessandra Palladini, Vasileia I. Alexaki, Michal A. Surma, Kai Simons, Triantafyllos Chavakis, Christian Klose, Ünal Coskun Published in: Molecular Metabolism, Issue 22, 2019, Page(s) 12-20, ISSN 2212-8778 Publisher: Elsevier GmbH DOI: 10.1016/j.molmet.2019.01.009 Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced Colitis Author(s): Baomei Wang, Jong-Hyung Lim, Tetsuhiro Kajikawa, Xiaofei Li, Bruce A. Vallance, Niki M. Moutsopoulos, Triantafyllos Chavakis, George Hajishengallis Published in: Cell Reports, Issue 26/6, 2019, Page(s) 1614-1626.e5, ISSN 2211-1247 Publisher: Cell Press DOI: 10.1016/j.celrep.2019.01.054 DEL-1 promotes macrophage efferocytosis and clearance of inflammation Author(s): Ioannis Kourtzelis, Xiaofei Li, Ioannis Mitroulis, Daniel Grosser, Tetsuhiro Kajikawa, Baomei Wang, Michal Grzybek, Janusz von Renesse, Aleksander Czogalla, Maria Troullinaki, Anaisa Ferreira, Christian Doreth, Klara Ruppova, Lan-Sun Chen, Kavita Hosur, Jong-Hyung Lim, Kyoung-Jin Chung, Sylvia Grossklaus, Anne Kathrin Tausche, Leo A. B. Joosten, Niki M. Moutsopoulos, Ben Wielockx, Antonio Castrill Published in: Nature Immunology, Issue 20/1, 2019, Page(s) 40-49, ISSN 1529-2908 Publisher: Nature Publishing Group DOI: 10.1038/s41590-018-0249-1 Hypoxia Pathway Proteins in Normal and Malignant Hematopoiesis Author(s): Ben Wielockx, Tatyana Grinenko, Peter Mirtschink, Triantafyllos Chavakis Published in: Cells, Issue 8/2, 2019, Page(s) 155, ISSN 2073-4409 Publisher: MDPI AG DOI: 10.3390/cells8020155 Hematopoietic progenitor cells as integrative hubs for adaptation to and fine-tuning of inflammation Author(s): Triantafyllos Chavakis, Ioannis Mitroulis, George Hajishengallis Published in: Nature Immunology, Issue 20/7, 2019, Page(s) 802-811, ISSN 1529-2908 Publisher: Nature Publishing Group DOI: 10.1038/s41590-019-0402-5 The Role of Innate Immune Cells in Nonalcoholic Fatty Liver Disease Author(s): Nati M.; Chung K.-J.; Chavakis T. Published in: Journal of Innate Immunity, Issue Vol.14; 1, 2022, Page(s) 31–41, ISSN 1662-811X Publisher: Karger AG DOI: 10.1159/000518407 An intrinsic role of IL-33 in Treg cell–mediated tumor immunoevasion Author(s): Aikaterini Hatzioannou, Aggelos Banos, Theodore Sakelaropoulos, Constantinos Fedonidis, Maria-Sophia Vidali, Maren Köhne, Kristian Händler, Louis Boon, Ana Henriques, Vasiliki Koliaraki, Panagiotis Georgiadis, Jerome Zoidakis, Aikaterini Termentzi, Marc Beyer, Triantafyllos Chavakis, Dimitrios Boumpas, Aristotelis Tsirigos, Panayotis Verginis Published in: Nature Immunology, Issue 21/1, 2020, Page(s) 75-85, ISSN 1529-2908 Publisher: Nature Publishing Group DOI: 10.1038/s41590-019-0555-2 Phagocytosis of Apoptotic Cells in Resolution of Inflammation Author(s): Ioannis Kourtzelis, George Hajishengallis, Triantafyllos Chavakis Published in: Frontiers in Immunology, Issue 11, 2020, ISSN 1664-3224 Publisher: Esther M. Lafuente DOI: 10.3389/fimmu.2020.00553 Loss of hepatic Mboat7 leads to liver fibrosis Author(s): Veera Raghavan Thangapandi, Oskar Knittelfelder, Mario Brosch, Eleonora Patsenker, Olga Vvedenskaya, Stephan Buch, Sebastian Hinz, Alexander Hendricks, Marina Nati, Alexander Herrmann, Devavrat Ravindra Rekhade, Thomas Berg, Madlen Matz-Soja, Klaus Huse, Edda Klipp, Josch K Pauling, Judith AH Wodke, Jacobo Miranda Ackerman, Malte von Bonin, Elmar Aigner, Christian Datz, Witigo von Schönfels, Soph Published in: Gut, Issue 70/5, 2021, Page(s) 940-950, ISSN 0017-5749 Publisher: BMJ Publishing Group DOI: 10.1136/gutjnl-2020-320853 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
