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New Quaternary Ammonium Salts for use in Drug Manufacture

Ziel

The aim of this project is to bring together subject matter experts from the academic and non-academic sectors to develop three new categories of quaternary ammonium salts to be used as catalysts for the cost-efficient and green manufacture of high value active pharmaceutical ingredients.
In order to achieve this objective the proposal brings together 3 partners with complementary skills:
University of Naples(UNIN): experts in the preparation and purification of cyclic peptides. Experts in solid phase synthesis and immobilisation of peptides on solid support.
KelAda Pharmachem: Phase transfer catalysis/organo catalysis/scale-up of chemical processes
University of Linz(JKU Linz): experts in design of new ammonium salts and optimisation of enantioselective phase transfer catalyses.

We have broken this proposal into the following separate Work Packages:
WP1. Preparation of new designer ammonium salts [WP leader: Kelada]
WP2. Preparation of cyclic peptide based ammonium salts [WP leader: UNINA]
WP3. Evaluation of new ammonium salt catalysts prepared through WP1 [WP JKULinz]
WP4. Evaluation of new Ammonium salt catalysts prepared through WP2[WP leader: UNINA]
WP5. Application of Ammonium salts to drug production [WP leader: Kelada]
WP6. Scale up of key steps or the manufacture of drugs [WP leader: Kelada]
WP 7. Management, Communication & Dissemination [WP leader: KelAda]

The above WP’s will be undertaken via a series of interlinked secondment of researchers between consortium partners and will be complemented by a series of training and other initiatives to facilitate interdisciplinary and intersectoral knowledge sharing and exchange.

Wissenschaftliches Gebiet (EuroSciVoc)

Programm/Programme

Thema/Themen

Finanzierungsplan

MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)

Alle im Rahmen dieses Finanzierungsinstruments finanzierten Projekte anzeigen

Aufforderung zur Vorschlagseinreichung

(öffnet in neuem Fenster) H2020-MSCA-RISE-2015

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Koordinator

UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II
Netto-EU-Beitrag
€ 432 000,00
Adresse
CORSO UMBERTO I, 40
80138 Napoli
Italien
Region
Sud Campania Napoli
Aktivitätstyp
Higher or Secondary Education Establishments
Links
Gesamtkosten
€ 432 000,00

Beteiligte (2)