CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.
I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .
Risultati finali
Report on the transcriptome analysis of larval stages and immune-related genes. High-throughput expression analysis will be performed on fish samples supplied with the bioactive compounds to evaluate regulatory pathways, using RNAseq technology
Stimulation of growth by methanol (si apre in una nuova finestra)Report on the effect of microalgae biomass production under mixotrophic conditions by addition of selected concentrations of methanol into the growth medium.
Transcriptome associated with novel bioactive products in microalgae (si apre in una nuova finestra)Report on the transcriptome analysis of selected microalgae strains grown under differential environmental and nutritional regimes associated with novel bioactive products, using RNAseq technology
In vitro toxicity assessments of microalgae extracts or compounds (si apre in una nuova finestra)Report on in vitro toxicity assessment of microalgae extracts or compounds using human dermal keratinocytes and normal human fibroblasts cell cultures
Report on the quality control of the cosmeceutical products (si apre in una nuova finestra)Report on the quality control of the cosmeceutical products at different storage conditions by using optical and physicochemical methods and microbiological testing.
Optimal conditions of photonic quality (si apre in una nuova finestra)Report on the optimization of microalgae biomass production under different light wavelengths, including white light, red light, green light and blue light.
Metabolomic profile of microalgae under different culture regimes (si apre in una nuova finestra)Report on the accumulation of a wide range of compounds spanning both primary and secondary metabolism under different growth conditions
Report on the effect of microalgae extracts or compounds on the transcription of skin-related genes using human cell lines. (si apre in una nuova finestra)Report on the the transcription effect of selected microalgae extracts or compounds on normal human keratinocytes and normal human fibroblasts in vitro using real-time RT-qPCR
Catalomic profile of microalgae under different culture regimes (si apre in una nuova finestra)Report on the activities of enzymes of cosmetic importance such as proteases, lipases, superoxide dismutase, catalase, peroxidase, under different growth conditions
Final project evaluation and assessment report (si apre in una nuova finestra)Final project evaluation and assessment report including external audits as necessary
Report on outreach activities to the general public (si apre in una nuova finestra)Report on the outreach activities aimed towards the general public including articles, videos etc.
Proceedings of the training workshops (si apre in una nuova finestra)Report on the proceeding and activities of the planned workshops which will be realised with in the project
Establish the main biological effects of novel nutraceuticals on fish performance (si apre in una nuova finestra)Report on the main biological effects of novel nutraceuticals on fish performance, including embryos from natural spawning of soles exposed to the biocompound to assess toxicity.
Detailed report on the training and transfer of knowledge obtained through the secondments (si apre in una nuova finestra)Report on the training and transfer of knowledge activities and skills obtained through the secondments plan for each secondee.
Purification and characterization of hatching enzyme (si apre in una nuova finestra)Report on the development of a proposed method for the purification and subsequent characterization of hatching enzyme, with a possible application in cosmetics
Progress reports and project evaluation and assessment reports (si apre in una nuova finestra)Detailed progress reports and progress evaluation and assessment reports including identification of possible risks during the project duration
Glycomic profile of microalgae under different culture regimes (si apre in una nuova finestra)Report on the yield and quality of polysaccharides production, including polysaccharide isolation, fractionation and structural characterization
Establish protocols for nutraceuticals administration (si apre in una nuova finestra)Report on the main biological effects of novel nutraceuticals on fish performance, including larval culture of soles under standard conditions and supplying microcapsules containing compounds until completion of metamorphosis.
Identification and characterization of high-value added enzymes (proteases, lipases and antioxidant enzymes) with potential applications in cosmetology (si apre in una nuova finestra)Report on the screening aiming at evaluating substrate specificity and activity of selected enzymes in algae extracts. The study will be focuses only on enzymes with interest in cosmetology
Purification and structural analysis of selected algae polysaccharides (si apre in una nuova finestra)Report on the purification and structural analysis of selected algae polysaccharides, including monosaccharide content determined by classical chromatography methods. Special attention will be paid on uronic and sulphate content which often carry the physico-chemical and biological properties of marine polysaccharides.
Progress report Month 36 (si apre in una nuova finestra)Reporting the clompletion of tasks, deliverables and milestons as set forth, including scientific repporting, financials, etc
Progress report Month 12 (si apre in una nuova finestra)Reporting the clompletion of tasks, deliverables and milestons as set forth, including scientific repporting, financials, etc...
Comparative model of human and fish keratinocyte response to microalgal extracts (si apre in una nuova finestra)Report on the comparative in vitro assessment and model development of human and fish keratinocyte response to microalgae extracts using selected in vitro enzyme assays and transcriptional effects.
Define the ontogeny of immune barriers and effects of nutraceuticals (si apre in una nuova finestra)Report on the ontogeny of immune barriers and effects of nutraceuticals, including survival and evaluation of growth, metamorphic success and malformations using skeletal staining techniques.
Optimization of growth under various growth media (si apre in una nuova finestra)Report on the optimization of microalgae biomass production in different growth media
Optimal conditions of light intensity (si apre in una nuova finestra)Report on the optimization of microalgae biomass production under different light intensities
Minutes of all managements meetings held (si apre in una nuova finestra)Minutes of all major meeting held for the management of the project
Development of a fish epithelial model and assessment of toxicity and impact on the transcriptome and enzyme activities of microalgal extracts (si apre in una nuova finestra)Report on the development of a fish epithelial model and assessment of toxicity and impact on the transcriptome and enzyme activities of microalgal extracts. Selected in vitro enzyme assays, transcriptional effects and in vitro toxicity/endocrine disruptor effects of microalgal extracts will included
Transfer of the optimal growth conditions from lab scale to the large scale photobioreactors (si apre in una nuova finestra)Report on the scale up and preculturing process would go through 500mL, 1L and 5L flasks to the 50L PBR reactors placed inside the artificial light room and finally to the outdoor PBRs placed inside a pilot plant greenhouse.
Proceedings of the Summer schools (si apre in una nuova finestra)Report on the proceeding and activities of summer schools which will be realised with in the project
Intellectual property and networking activities report (si apre in una nuova finestra)Report on the management of Intellectual property and networking activities management between the members of the consortium
Mapping bioactive properties using in vitro enzyme bioassays (si apre in una nuova finestra)Report on the screening and examination of bioactivity of algae extracts by evaluating the inhibition potency of extracts towards enzyme targets of importance for the cosmetic industry
Steady-state kinetic characterization of enzymes and thermodynamics analysis of the enzyme stability (si apre in una nuova finestra)Report on the kinetic and stability characterization of the new isolated enzymes. Steady-state kinetic analysis will be used to characterize the kinetic parameters of the enzymes.
A downstream processing protocol for enzymes purification (si apre in una nuova finestra)Report on the development of an application based downstream processing protocol for enzymes purification with an emphasis in the development of a single-step, low cost and environmental friendly method for enzyme purification
Scientific publications in international peer-review scientific journals and conferences attended by members of the consortium
Biannual e-newsletters (si apre in una nuova finestra)A bi-annual e-newsletter will inform end users and stakeholders on scientific progress, job opportunities and upcoming events regarding the scope of this project.
Analytical Handbook (si apre in una nuova finestra)An analytical handbook containing main protocols and procedures developed by the partners with in the duration of the project
A project website containing all the information regarding the scope and activities of the consortium during the implementation of the project
Training and e-learning web-site (si apre in una nuova finestra)A web-site containing Training and e-learning material produced by the project
Pubblicazioni
Autori:
Joana Firmino, Carlos Carballo, Paula Armesto, Marco A. Campinho, Deborah M. Power, Manuel Manchado
Pubblicato in:
BMC Developmental Biology, Numero 17/1, 2017, ISSN 1471-213X
Editore:
BioMed Central
DOI:
10.1186/s12861-017-0154-0
Autori:
Carlos Carballo, Evangelia G. Chronopoulou, Sofia Letsiou, Claudia Maya, Nikolaos E. Labrou, Carlos Infante, Deborah M. Power, Manuel Manchado
Pubblicato in:
Fish & Shellfish Immunology, Numero 82, 2018, Pagina/e 1-8, ISSN 1050-4648
Editore:
Academic Press
DOI:
10.1016/j.fsi.2018.07.052
Autori:
Patricia I. S. Pinto, Cláudia C. Guerreiro, Rita A. Costa, Juan F. Martinez-Blanch, Carlos Carballo, Francisco M. Codoñer, Manuel Manchado, Deborah M. Power
Pubblicato in:
Scientific Reports, Numero 9/1, 2019, ISSN 2045-2322
Editore:
Nature Publishing Group
DOI:
10.1038/s41598-019-49501-6
Autori:
Maria Patelou, Carlos Infante, Flavien Dardelle, Dörte Randewig, Evangelia D. Kouri, Michael K. Udvardi, Eleni Tsiplakou, Lalia Mantecón, Emmanouil Flemetakis
Pubblicato in:
Algal Research, Numero 45, 2020, Pagina/e 101735, ISSN 2211-9264
Editore:
Elsevier BV
DOI:
10.1016/j.algal.2019.101735
Autori:
Sophia Letsiou, Rute Felix, João C. Cardoso, Liliana Anjos, Ana L. Mestre, Henirique L. Gomes, Deborah M. Power
Pubblicato in:
Biochimie, 2020, ISSN 0300-9084
Editore:
Elsevier BV
DOI:
10.1016/j.biochi.2020.02.008
Autori:
Carlos Carballo, Patricia I.S. Pinto, Ana Patricia Mateus, Concha Berbel, Cláudia C. Guerreiro, Juan F. Martinez-Blanch, Francisco M. Codoñer, Lalia Mantecon, Deborah M. Power, Manuel Manchado
Pubblicato in:
Fish & Shellfish Immunology, Numero 92, 2019, Pagina/e 31-39, ISSN 1050-4648
Editore:
Academic Press
DOI:
10.1016/j.fsi.2019.05.044
Autori:
Carlos Carballo, Evangelia G. Chronopoulou, Sophia Letsiou, Eleni Spanidi, Konstantinos Gardikis, Nikolaos E. Labrou, Manuel Manchado
Pubblicato in:
PLOS ONE, Numero 14/12, 2019, Pagina/e e0225666, ISSN 1932-6203
Editore:
Public Library of Science
DOI:
10.1371/journal.pone.0225666
Autori:
Konstantinos Gardikis, Manuel Manchado, Israel Guerrero-Cózar, Claudia Maya, Carlos Infante, Sophia Letsiou, Vasiliki-Ioanna Boka, William Helbert
Pubblicato in:
BIT’s 8th Annual International Symposium of Drug Delivery Systems (SDDS-2018), 2018
Editore:
Not known
Autori:
Konstantinos Gardikis, Sophia Letsiou
Pubblicato in:
30th International Symposium on the Chemistry of Natural Products, 2018
Editore:
Not known
Autori:
Ioanna Anastasiou, Katerina I. Kalliampakou, Sophia Letsiou, Carlos Infante , William Helbert, Kostantinos Gardikis, Lalia Mantecon and Emmanouil Flemetakis.
Pubblicato in:
10th European Conferenceon Marine Natural Products proceedings, 2017
Editore:
10th European Conferenceon Marine Natural Products proceedings
Autori:
Félix RC, Letsiou S, Anjos L, Gomes HL, Power DM
Pubblicato in:
4th Conference on Impedance-Based Cell Assays (IBCA2018), 2018
Editore:
IBCA
Autori:
Patrícia Pinto, C Carballo, AP Mateus, J Martinez-Blanch, F Codoner, L Mantecon, M Manchado, DM Power
Pubblicato in:
31th New European Soc. for Comparative Physiology and Biochemistry (ESCPB 2018), 2018
Editore:
Not known
Autori:
Ioanna Anastasiou, Sophia Letsiou, Katerina I. Kalliampakou, Carlos Infante , William Helbert, Kostantinos Gardikis, Lalia Mantecón and Emmanouil Flemetakis
Pubblicato in:
Proceedings of the 68th Helenic Biochemistry and Molecular Biology Society, 2017
Editore:
68th Helenic Biochemistry and Molecular Biology Society
Autori:
Anjos L, Cardoso JCR, Gardikis K, Power DM and Letsiou S
Pubblicato in:
10th European Conferenceon Marine Natural Products proceedings, 2017
Editore:
10th European Conferenceon Marine Natural Products proceedings
Autori:
Manuel Manchado
Pubblicato in:
2018
Editore:
SIBIC2018, the VII Congress of the Iberian Society for Ichthyology
Autori:
Pinto PIS, Guerreiro C, Costa RA, Martinez-Blanch JF, Carballo C, Codoñer F, Manchado M, Power DM
Pubblicato in:
VII Congress of the Iberian Soc. for Ichthyology, 2018
Editore:
Proceedings of the VII Congress of the Iberian Soc. for Ichthyology
Autori:
Ana Manuela Crespo1, Carlos Carballo1, Lalia Mantecón2y Manuel Manchado1
Pubblicato in:
2018
Editore:
Not known
Autori:
Carballo C.1*, Chronopoulou E.2, Crespo A.1, Gardikis K.3, Labrou N.2, Manchado M.
Pubblicato in:
International Flatfish Symposium 2017, 2017
Editore:
International Flatfish Symposium 2017
Autori:
Carlos Carballo, Evangelia G. Chronopoulou; Sofia Letsiou; Claudia Maya; Nikolaos E. Labrou; Carlos Infante; Deborah M. Power; Manuel Manchado
Pubblicato in:
IX Jornadas de Acuicultura en el Litoral Suratlántico - La Acuicultura Progresa, 2018
Editore:
IX Jornadas de Acuicultura en el Litoral Suratlántico
Autori:
P. Pinto (CCMAR)
Pubblicato in:
Invited talk at research centre UMR I-02 SEBIO, University le Havre-Normandie (France), 2019
Editore:
NA
Autori:
C. Carballo
Pubblicato in:
2020
Editore:
University of Malaga
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