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Novel natural products for healthy ageing from Mediterranean diet and food plants of other global sources

Resultado final

Establishment of a website

A website for Medihealth project will be established and will publish project results and activities as well as disseminate information towards a general public and to industry. Specific web space will be available for the foreseen outreach activities of the consortium and information related to the already implemented ones.

Publicaciones

Phytochemical Analysis and Antioxidant Potential of the Phytonutrient-Rich Decoction of Cichorium spinosum and C. intybus

Autores: Vincent Brieudes, Apostolis Angelis, Konstantina Vougogiannopoulou, Harris Pratsinis, Dimitris Kletsas, Sofia Mitakou, Maria Halabalaki, Leandros Skaltsounis
Publicado en: Planta Medica, 82/11/12, 2016, Page(s) 1070-1078, ISSN 0032-0943
Editor: Georg Thieme Verlag
DOI: 10.1055/s-0042-107472

Inhibition of Pro-Inflammatory Functions of Human Neutrophils by Constituents of Melodorum fruticosum Leaves

Autores: Nora S. Engels, Birgit Waltenberger, Barbara Michalak, Loi Huynh, Hung Tran, Anna K. Kiss, Hermann Stuppner
Publicado en: Chemistry & Biodiversity, 15/11, 2018, Page(s) e1800269, ISSN 1612-1872
Editor: Verlag Helvetica Chimica Acta
DOI: 10.1002/cbdv.201800269

Novel Natural Products for Healthy Ageing from the Mediterranean Diet and Food Plants of Other Global Sources—The MediHealth Project

Autores: Waltenberger, Birgit; Halabalaki, Maria; Schwaiger, Stefan; Adamopoulos, Nicolas; Allouche, Noureddine; Fiebich, Bernd L; Hermans, Nina; Jansen-Dürr, Pidder; Kesternich, Victor; Pieters, Luc; Schönbichler, Stefan; Skaltsounis, Alexios-Leandros; Tran, Hung; Trougakos, Ioannis P; Viljoen, Alvaro; Wolfender, Jean-Luc; Wolfrum, Christian; Xynos, Nikos; Stuppner, Hermann
Publicado en: Molecules, 23(5), 2018, Page(s) 1097, ISSN 1420-3049
Editor: Multidisciplinary Digital Publishing Institute (MDPI)

Phytochemical Composition of the Decoctions of Greek Edible Greens (Chórta) and Evaluation of Antioxidant and Cytotoxic Properties

Autores: Eleni Mikropoulou, Konstantina Vougogiannopoulou, Eleftherios Kalpoutzakis, Aimilia Sklirou, Zoi Skaperda, Joëlle Houriet, Jean-Luc Wolfender, Ioannis Trougakos, Dimitrios Kouretas, Maria Halabalaki, Sofia Mitakou
Publicado en: Molecules, 23/7, 2018, Page(s) 1541, ISSN 1420-3049
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules23071541

Targeting Protein Quality Control Mechanisms by Natural Products to Promote Healthy Ageing

Autores: Sophia Wedel, Maria Manola, Maria Cavinato, Ioannis Trougakos, Pidder Jansen-Dürr
Publicado en: Molecules, 23/5, 2018, Page(s) 1219, ISSN 1420-3049
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules23051219

Proteome Stability as a Key Factor of Genome Integrity

Autores: Sentiljana Gumeni, Zoi Evangelakou, Vassilis Gorgoulis, Ioannis Trougakos
Publicado en: International Journal of Molecular Sciences, 18/10, 2017, Page(s) 2036, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms18102036

Extracts from the Mediterranean Food Plants Carthamus lanatus , Cichorium intybus , and Cichorium spinosum Enhanced GSH Levels and Increased Nrf2 Expression in Human Endothelial Cells

Autores: Dimitrios Stagos, Dimitrios Balabanos, Salomi Savva, Zoi Skaperda, Alexandros Priftis, Efthalia Kerasioti, Eleni V. Mikropoulou, Konstantina Vougogiannopoulou, Sofia Mitakou, Maria Halabalaki, Demetrios Kouretas
Publicado en: Oxidative Medicine and Cellular Longevity, 2018, 2018, Page(s) 1-14, ISSN 1942-0900
Editor: Landes Bioscience
DOI: 10.1155/2018/6594101

EXPLORATION OF DIETARY PLANTS FROM WORLDWIDE BIODIVERSITY AIMING THE DISCOVERY OF ACTIVE AGENTS WITH ANTI-AGEING EFFECTS

Autores: Maria-Eleni Sakavitsi, Zoi Evangelakou, Gabriela Belen Lemus Ringele, Amal Ghorbel, Aikaterini Argyropoulou, Victor Kesternich, Noureddine Allouche, Ioannis Trougakos, Maria Halabalaki, Leandros Skaltsounis
Publicado en: International Conference On Natural Products Utilization: from Plants to Farmacy Shelf (ICNPU 2017), Proceedings PP192, 2017, Page(s) 20
Editor: ICNPU 2017

Phytochemical investigation of the Chilean berries Aristotelia chilensis and Ugni molinae. Evaluation of their anti-ageing effects employing a Drosophila model.

Autores: ME Sakavitsi, Z Evangelakou, A Faúndez Catherine, G Lemus Belen Ringele, A Argyropoulou, V Kesternich, I Trougakos, M Halabalaki, A Skaltsounis Leandros
Publicado en: 65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017), 2017
Editor: Georg Thieme Verlag KG
DOI: 10.1055/s-0037-1608278

Sclerocarya birrea cortex ethanolic extract – Chemical characterisation and NOX4 inhibition (anti-ageing property)

Autores: N Mncwangi, B Waltenberger, G Baraldo, P Jansen-Dürr, A Viljoen, H Stuppner
Publicado en: 65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017), 2017
Editor: Georg Thieme Verlag KG
DOI: 10.1055/s-0037-1608258

MediHealth – an interdisciplinary and international research and innovation staff exchange project to identify novel natural products for healthy ageing

Autores: B Waltenberger, N Adamopoulos, N Allouche, B Fiebich, M Halabalaki, P Jansen-Dürr, V Kesternich, L Pieters, S Schönbichler, LA Skaltsounis, H Tran, IP Trougakos, A Viljoen, J-L Wolfender, C Wolfrum, N Xynos, H Stuppner
Publicado en: 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP, 85(18), 2019, Page(s) 1572
Editor: Georg Thieme Verlag KG
DOI: 10.1055/s-0039-3400404

Novel natural products for healthy ageing from Mediterranean diet and food plants of other global sources - the MediHealth project

Autores: Waltenberger B., Adamopoulos N., Allouche N., Fiebich B., Halabalaki M., Heinke R., Jansen-Dürr P., Kesternich V., Pieters L., Queiroz E.F., Schönbichler S., Schwaiger S., Skaltsounis A.-L., Tran H., Trougakos I.P., Viljoen A., Wolfender J.-L., Wolfrum C., Xynos N., Stuppner H.
Publicado en: PHYTO Valley - First Austrian Summit on Natural Products, 2018
Editor: Phytovalley

Simulating Human Gastrointestinal and colonic biotransformation pathways through and in vitro assay reveals insight on hydroxytyrosol and oleuropein metabolism

Autores: ME Sakavitsi, A Breynaert, A Angelis, L Pieters, N Hermans, S Mitakou, M Halabalaki
Publicado en: Young Researchers Workshop GA 2019, 2019
Editor: Thieme

Simulating human gastrointestinal and colonic biotranformation pathways through an in vitro assay reveals insight on hydroxytyrosol and oleuropein metabolism

Autores: ME Sakavitsi, A Breynaert, A Angelis, L Pieters, N Hermans, S Mitakou, M Halabalaki
Publicado en: 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP, 2019
Editor: © Georg Thieme Verlag KG
DOI: 10.1055/s-0039-3399660

A holistic UPLC-HRMS-based approach exploring the phytochemistry, bioactivity and metabolome impact of Cichorium spinosum’ s decoction in Drosophila melanogaster

Autores: EV Mikropoulou, Z Evangelakou, M Manola, S Gumeni, IP Trougakos, LA Skaltsounis, M Halabalaki
Publicado en: 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP, 2019
Editor: © Georg Thieme Verlag KG
DOI: 10.1055/s-0039-3399823

Nrf2 as a central hub in the wiring of proteostatic, mitostatic and metabolic pathways

Autores: Ioannis P. Trougakos
Publicado en: 68th Panhellenic Congress of the Greek Biochemical and Molecular Biology Society, Proceedings Lecture 14, 2017, Page(s) 12
Editor: Greek Biochemical and Molecular Biology Society

Proteostasis network deregulation as a main molecular link of ageing and carcinogenesis

Autores: Ioannis P. Trougakos
Publicado en: 39th ANNUAL CONFERENCE OF THE HELLENIC SOCIETY FOR BIOLOGICAL SCIENCES, Proceedings Lecture, 2017
Editor: HELLENIC SOCIETY FOR BIOLOGICAL SCIENCES

Nrf2 as a main hub in the wiring of proteostatic, mitostatic and metabolic pathways

Autores: Eleni N. Tsakiri, Sentiljana Gumeni, Kalliopi K. Iliaki, Dimitra Benaki, Konstantinos Vougas, Gerasimos P. Sykiotis, Vassilis G. Gorgoulis, Emmanuel Mikros, Luca Scorrano and Ioannis P. Trougakos
Publicado en: COST Action BM1307 PROTEOSTASIS, Proteostatic Mechanisms in Health & Disease, Proceedings Oral Presentation, 2018
Editor: The Final COST Action BM1307 Meeting

Chapter 6: Impact of Loss of Proteostasis on Central Nervous System Disorders

Autores: Sentiljana Gumeni, Eleni N. Tsakiri, Christina-Maria Cheimonidi, Zoi Evangelakou, Despoina Gianniou, Kostantinos Tallas, Eleni-Dimitra Papanagnou, Aimilia D. Sklirou, Ioannis P. Trougakos
Publicado en: Protein Folding Disorders of the Central Nervous System, 2017, Page(s) 131-162, ISBN 978-981-3222-95-3
Editor: World Scientific Publishing
DOI: 10.1142/9789813222960_0006

Chapter 8: Impact of Mitostasis and the Role of the Anti-oxidant Responses on Central Nervous System Disorders

Autores: Sentiljana Gumeni, Eleni N. Tsakiri, Christina-Maria Cheimonidi, Zoi Evangelakou, Despoina Gianniou, Kostantinos Tallas, Eleni-Dimitra Papanagnou, Aimilia D. Sklirou, Ioannis P. Trougakos
Publicado en: Protein Folding Disorders of the Central Nervous System, 2017, Page(s) 185-201, ISBN 978-981-3222-95-3
Editor: World Scientific Publishing
DOI: 10.1142/9789813222960_0008