Widening the Scientific Excellence for Studies on Women’s and Fetal Health and Wellbeing

Risultati finali

First workshop held on “female reproduction: ovulatory disorders”

Deliverable generated as a result of Task 4.1.

Report on utilizing the UTARTU’s endometrial biopsies for practical training (1)

The deliverable will be generated as a result of Task 1.4.

Co-authored article on female metabolic health as a predictor of fertility as a result of a PhD student’s short-term stay in UOXF (1)

Deliverable generated as a result of Task 2.1.

Report on off-site virtual trainings and consultations performed to apply the NIPT methods within clinical use at UTARTU (1)

Deliverable generated as a result of Task 1.6.

Report on on-site and off-site trainings performed between UTARTU and UOXF to transfer knowledge for analysing female reproductive ageing

Deliverable is generated as a result of Task 2.2.

Joint article written on fetal non-invasive genetic testing

Deliverable generated as a result of Task 4.2.

Workshop held on single cell genomics

Deliverable generated as a result of Task 4.1.

Report on off-site virtual trainings and consultations performed to apply the NIPT methods within clinical use at UTARTU (3)

Deliverable generated as a result of Task 1.6.

Biobank samples shared for learning purposes (1)

The deliverable is generated as part of Task 1.2.

Biobank samples shared for learning purposes (3)

The deliverable is generated as a result of Task 1.2.

Summer school held in Tartu, Estonia

Deliverable generated as a result of Task 4.1.

Co-authored article on female reproductive ageing as a result of a PhD students’ short-term stay in UOXF (2)

Deliverable generated as a result of Task 2.2.

Co-authored article on human preimplantation embryos as a result of PhD students’ short-term stay in KU LEUVEN (1)

Deliverable generated as a result of Task 2.4.

Report on cross-applying opportunities for EGCUT and WTCCC datasets

The deliverable will be generated as a result of Task 1.3.

Report on utilizing the UTARTU’s endometrial biopsies for practical training (2)

The deliverable will be generated as a result of Task 1.4.

Report 2 on dissemination performed as part of local events for the scientific and local communities

Deliverable generated as a result of Task 4.5.

Co-authored article on analysing and implementing fetal non-invasive genetic testing as a result of a PhD student’s short-term stay in KU LEUVEN

Deliverable generated as a result of Task 2.5.

Co-authored article on female metabolic health as a predictor of fertility as a result of a post-doc’s short-term stay in UOXF (2)

Deliverable generated as a result of Task 2.1.

Joint article written on human preimplantation embryos

Deliverable generated as a result of Task 4.2.

Report 1 on dissemination performed as part of international conferences

Deliverable generated as a result of Task 4.3.

Second workshop held on “female reproduction: ovulatory disorders”

Deliverable generated as a result of Task 4.1.

Senior staff exchanges completed between UTARTU and KU LEUVEN to transfer knowledge for isolating and amplifying DNA and RNA from single blastomere cells and to deploy time-lapse and NIPT methods

Deliverable generated as a result of Task 1.5 and Task 1.6.

Joint article written on female metabolic health as a predictor of fertility

Deliverable generated as a result of Task 4.2.

Report 3 on dissemination performed as part of international conferences

Deliverable generated as a result of Task 4.3.

Joint article written on female reproductive ageing

Deliverable generated as a result of Task 4.2.

Co-authored article on female reproductive ageing as a result of a PhD students’ short-term stay in UOXF (1)

Deliverable generated as a result of Task 2.2.

Joint article written on endometrial receptivity, implantation and endometriosis

Deliverable generated as a result of Task 4.2.

Report on on-site and off-site trainings performed between UTARTU and UOXF to transfer knowledge on female metabolic health as a predictor of fertility

Report generated as a result of Task 2.1.

Co-authored article on human preimplantation embryos as a result of PhD students’ short-term stay in KU LEUVEN (2)

Deliverable generated as a result of Task 2.4.

Report 3 on dissemination performed as part of local events for the scientific and local communities

Deliverable generated as a result of Task 4.4 and Task 4.5.

Report 2 on dissemination performed as part of international conferences

Deliverable generated as a result of Task 4.3.

Co-authored article on analysing and implementing fetal non-invasive genetic testing as a result of a post-doc’s short-term stay in KU LEUVEN

Deliverable generated as a result of Task 2.5.

Biobank samples shared for learning purposes (5)

The deliverable is generated as a result of Task 1.2.

Biobank samples shared for learning purposes (4)

The deliverable is generated as a result of Task 1.2.

Report 1 on dissemination performed as part of local events for the scientific and local communities

Deliverable generated as a result of Task 4.5.

Co-authored article on endometrial receptivity, implantation and endometriosis as a result of a PhD student’s short-term stay in UOXF

Deliverable generated as a result of Task 2.3.

Report on off-site virtual trainings and consultations performed to apply the NIPT methods within clinical use at UTARTU (2)

Deliverable generated as a result of Task 1.6.

Biobank samples shared for learning purposes (2)

The deliverable is generated as a result of Task 1.2.

Co-authored article on female reproductive ageing as a result of a post-doc’s short-term stay in UOXF

Report generated as a result of Task 2.2.

Test for non-invasive identification of endometriosis, which has been validated in partner organisations

Deliverable is generated as a result of Tasks 3.1 - 3.3.

Clinical use of NIPT technology

Deliverable generated as a result of Tasks 3.1 - 3.3.

NIPT technology adopted in an initial format by UTARTU’s scientists

Deliverable generated as a result of Tasks 3.1 - 3.3.

Clinical use of PGS in Tartu University Hospital

Deliverable generated as a result of Tasks 3.1 - 3.3.

Pubblicazioni

rs10732516 polymorphism at the IGF2/H19 locus associates with genotype-specific effects on placental DNA methylation and birth weight of newborns conceived by assisted reproductive technology

Autori: Heidi Marjonen, Pauliina Auvinen, Hanna Kahila, Olga Tšuiko, Sulev Kõks, Airi Tiirats, Triin Viltrop, Timo Tuuri, Viveca Söderström-Anttila, Anne-Maria Suikkari, Andres Salumets, Aila Tiitinen, Nina Kaminen-Ahola
Pubblicato in: Clinical Epigenetics, Numero 10/1, 2018, ISSN 1868-7075
Editore: Springer Verlag
DOI: 10.1186/s13148-018-0511-2

NIPTmer: rapid k-mer-based software package for detection of fetal aneuploidies

Autori: Martin Sauk, Olga Žilina, Ants Kurg, Eva-Liina Ustav, Maire Peters, Priit Paluoja, Anne Mari Roost, Hindrek Teder, Priit Palta, Nathalie Brison, Joris R. Vermeesch, Kaarel Krjutškov, Andres Salumets, Lauris Kaplinski
Pubblicato in: Scientific Reports, Numero 8/1, 2018, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-018-23589-8

Variability of genome-wide DNA methylation and mRNA expression profiles in reproductive and endocrine disease related tissues

Autori: Nilufer Rahmioglu, Alexander W Drong, Helen Lockstone, Thomas Tapmeier, Karin Hellner, Merli Saare, Triin Laisk-Podar, Christine Dew, Emily Tough, George Nicholson, Maire Peters, Andrew P Morris, Cecilia M Lindgren, Christian M Becker, Krina T Zondervan
Pubblicato in: Epigenetics, Numero 12/10, 2017, Pagina/e 897-908, ISSN 1559-2294
Editore: Landes Bioscience
DOI: 10.1080/15592294.2017.1367475

DNA methylation changes in endometrium and correlation with gene expression during the transition from pre-receptive to receptive phase

Autori: Viktorija Kukushkina, Vijayachitra Modhukur, Marina Suhorutšenko, Maire Peters, Reedik Mägi, Nilufer Rahmioglu, Agne Velthut-Meikas, Signe Altmäe, Francisco J. Esteban, Jaak Vilo, Krina Zondervan, Andres Salumets, Triin Laisk-Podar
Pubblicato in: Scientific Reports, Numero 7/1, 2017, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-017-03682-0

The management of menopause in women with a history of endometriosis: a systematic review

Autori: L.C. Gemmell, K.E. Webster, S. Kirtley, K. Vincent, K.T. Zondervan, C.M. Becker
Pubblicato in: Human Reproduction Update, Numero 23/4, 2017, Pagina/e 481-500, ISSN 1355-4786
Editore: Oxford University Press
DOI: 10.1093/humupd/dmx011

The Influence of Different Maternal Microbial Communities on the Development of Infant Gut and Oral Microbiota

Autori: Tiina Drell, Jelena Štšepetova, Jaak Simm, Kristiina Rull, Aira Aleksejeva, Anne Antson, Vallo Tillmann, Madis Metsis, Epp Sepp, Andres Salumets, Reet Mändar
Pubblicato in: Scientific Reports, Numero 7/1, 2017, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-017-09278-y

Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions

Autori: Dmitry Shungin, Wei Q. Deng, Tibor V. Varga, Jian'an Luan, Evelin Mihailov, Andres Metspalu, Andrew P. Morris, Nita G. Forouhi, Cecilia Lindgren, Patrik K. E. Magnusson, Nancy L. Pedersen, Göran Hallmans, Audrey Y. Chu, Anne E. Justice, Mariaelisa Graff, Thomas W. Winkler, Lynda M. Rose, Claudia Langenberg, L. Adrienne Cupples, Paul M. Ridker, Nicholas J. Wareham, Ken K. Ong, Ruth J. F. Loos, Dan
Pubblicato in: PLOS Genetics, Numero 13/6, 2017, Pagina/e e1006812, ISSN 1553-7404
Editore: PLOS Genetics
DOI: 10.1371/journal.pgen.1006812

A Two-Cohort RNA-seq Study Reveals Changes in Endometrial and Blood miRNome in Fertile and Infertile Women

Autori: Kadri Rekker, Signe Altmäe, Marina Suhorutshenko, Maire Peters, Juan F. Martinez-Blanch, Francisco M. Codoñer, Felipe Vilella, Carlos Simón, Andres Salumets, Agne Velthut-Meikas
Pubblicato in: Genes, Numero 9/12, 2018, Pagina/e 574, ISSN 2073-4425
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes9120574

Differentially-Expressed miRNAs in Ectopic Stromal Cells Contribute to Endometriosis Development: The Plausible Role of miR-139-5p and miR-375

Autori: Kadri Rekker, Tõnis Tasa, Merli Saare, Külli Samuel, Ülle Kadastik, Helle Karro, Martin Götte, Andres Salumets, Maire Peters
Pubblicato in: International Journal of Molecular Sciences, Numero 19/12, 2018, Pagina/e 3789, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms19123789

Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

Autori: Felix Day, Tugce Karaderi, Michelle R. Jones, Cindy Meun, Chunyan He, Alex Drong, Peter Kraft, Nan Lin, Hongyan Huang, Linda Broer, Reedik Magi, Richa Saxena, Triin Laisk, Margrit Urbanek, M. Geoffrey Hayes, Gudmar Thorleifsson, Juan Fernandez-Tajes, Anubha Mahajan, Benjamin H. Mullin, Bronwyn G. A. Stuckey, Timothy D. Spector, Scott G. Wilson, Mark O. Goodarzi, Lea Davis, Barbara Obermayer-Pietsc
Pubblicato in: PLOS Genetics, Numero 14/12, 2018, Pagina/e e1007813, ISSN 1553-7404
Editore: PLOS Genetics
DOI: 10.1371/journal.pgen.1007813

Large-scale meta-analysis highlights the hypothalamic–pituitary–gonadal axis in the genetic regulation of menstrual cycle length

Autori: Triin Laisk, Viktorija Kukuškina, Duncan Palmer, Samantha Laber, Chia-Yen Chen, Teresa Ferreira, Nilufer Rahmioglu, Krina Zondervan, Christian Becker, Jordan W Smoller, Margaret Lippincott, Andres Salumets, Ingrid Granne, Stephanie Seminara, Benjamin Neale, Reedik Mägi, Cecilia M Lindgren
Pubblicato in: Human Molecular Genetics, 2018, ISSN 0964-6906
Editore: Oxford University Press
DOI: 10.1093/hmg/ddy317

GWAS Identifies Risk Locus for Erectile Dysfunction and Implicates Hypothalamic Neurobiology and Diabetes in Etiology

Autori: Jonas Bovijn, Leigh Jackson, Jenny Censin, Chia-Yen Chen, Triin Laisk, Samantha Laber, Teresa Ferreira, Sara L. Pulit, Craig A. Glastonbury, Jordan W. Smoller, Jamie W. Harrison, Katherine S. Ruth, Robin N. Beaumont, Samuel E. Jones, Jessica Tyrrell, Andrew R. Wood, Michael N. Weedon, Reedik Mägi, Benjamin Neale, Cecilia M. Lindgren, Anna Murray, Michael V. Holmes
Pubblicato in: The American Journal of Human Genetics, Numero 104/1, 2019, Pagina/e 157-163, ISSN 0002-9297
Editore: University of Chicago Press
DOI: 10.1016/j.ajhg.2018.11.004

Genome-wide haplotyping embryos developing from 0PN and 1PN zygotes increases transferrable embryos in PGT-M

Autori: Aspasia Destouni, Eftychia Dimitriadou, Heleen Masset, Sophie Debrock, Cindy Melotte, Kris Van Den Bogaert, Masoud Zamani Esteki, Jia Ding, Thiery Voet, Ellen Denayer, Thomy de Ravel, Eric Legius, Christel Meuleman, Karen Peeraer, Joris R Vermeesch
Pubblicato in: Human Reproduction, 2018, ISSN 0268-1161
Editore: Oxford University Press
DOI: 10.1093/humrep/dey325

Endometrial receptivity revisited: endometrial transcriptome adjusted for tissue cellular heterogeneity

Autori: Marina Suhorutshenko, Viktorija Kukushkina, Agne Velthut-Meikas, Signe Altmäe, Maire Peters, Reedik Mägi, Kaarel Krjutškov, Mariann Koel, Francisco M Codoñer, Juan Fco Martinez-Blanch, Felipe Vilella, Carlos Simón, Andres Salumets, Triin Laisk
Pubblicato in: Human Reproduction, Numero 33/11, 2018, Pagina/e 2074-2086, ISSN 0268-1161
Editore: Oxford University Press
DOI: 10.1093/humrep/dey301

Karyotype of the blastocoel fluid demonstrates low concordance with both trophectoderm and inner cell mass

Autori: Olga Tšuiko, Daria I. Zhigalina, Tatjana Jatsenko, Nikolay A. Skryabin, Olga R. Kanbekova, Victoria G. Artyukhova, Anatoly V. Svetlakov, Katre Teearu, Aleksander Trošin, Andres Salumets, Ants Kurg, Igor N. Lebedev
Pubblicato in: Fertility and Sterility, Numero 109/6, 2018, Pagina/e 1127-1134.e1, ISSN 0015-0282
Editore: Elsevier BV
DOI: 10.1016/j.fertnstert.2018.02.008

Aberrant expression of genes associated with stemness and cancer in endometria and endometrioma in a subset of women with endometriosis

Autori: Sakthivignesh Ponandai-Srinivasan, Karin L Andersson, Monica Nister, Merli Saare, Halima A Hassan, Suby J Varghese, Maire Peters, Andres Salumets, Kristina Gemzell-Danielsson, Parameswaran Grace Luther Lalitkumar
Pubblicato in: Human Reproduction, Numero 33/10, 2018, Pagina/e 1924-1938, ISSN 0268-1161
Editore: Oxford University Press
DOI: 10.1093/humrep/dey241

Thinning and drilling laser-assisted hatching in thawed embryo transfer: A randomized controlled trial

Autori: Minh Tam Le, Thi Tam An Nguyen, Thi Thai Thanh Nguyen, Van Trung Nguyen, Dinh Duong Le, Vu Quoc Huy Nguyen, Ngoc Thanh Cao, Alar Aints, Andres Salumets
Pubblicato in: Clinical and Experimental Reproductive Medicine, Numero 45/3, 2018, Pagina/e 129, ISSN 2233-8233
Editore: Korean Society for Reproductive Medicine
DOI: 10.5653/cerm.2018.45.3.129

DNA methylation alterations—potential cause of endometriosis pathogenesis or a reflection of tissue heterogeneity?†

Autori: Merli Saare, Kertu Liis Krigul, Triin Laisk-Podar, Sakthivignesh Ponandai-Srinivasan, Nilufer Rahmioglu, Parameswaran Grace Lalit Kumar, Krina Zondervan, Andres Salumets, Maire Peters
Pubblicato in: Biology of Reproduction, Numero 99/2, 2018, Pagina/e 273-282, ISSN 0006-3363
Editore: Society for the Study of Reproduction
DOI: 10.1093/biolre/ioy067

A speculative outlook on embryonic aneuploidy: Can molecular pathways be involved?

Autori: Olga Tšuiko, Tatjana Jatsenko, Lalit Kumar Parameswaran Grace, Ants Kurg, Joris Robert Vermeesch, Fredrik Lanner, Signe Altmäe, Andres Salumets
Pubblicato in: Developmental Biology, 2018, ISSN 0012-1606
Editore: Academic Press
DOI: 10.1016/j.ydbio.2018.01.014

Principles guiding embryo selection following genome-wide haplotyping of preimplantation embryos

Autori: Eftychia Dimitriadou, Cindy Melotte, Sophie Debrock, Masoud Zamani Esteki, Kris Dierickx, Thierry Voet, Koen Devriendt, Thomy de Ravel, Eric Legius, Karen Peeraer, Christel Meuleman, Joris Robert Vermeesch
Pubblicato in: Human Reproduction, Numero 32/3, 2017, Pagina/e 687-697, ISSN 0268-1161
Editore: Oxford University Press
DOI: 10.1093/humrep/dex011

Genome stability of bovine in vivo-conceived cleavage-stage embryos is higher compared to in vitro-produced embryos

Autori: Olga Tšuiko, Maaike Catteeuw, Masoud Zamani Esteki, Aspasia Destouni, Osvaldo Bogado Pascottini, Urban Besenfelder, Vitezslav Havlicek, Katrien Smits, Ants Kurg, Andres Salumets, Thomas D’Hooghe, Thierry Voet, Ann Van Soom, Joris Robert Vermeesch
Pubblicato in: Human Reproduction, Numero 32/11, 2017, Pagina/e 2348-2357, ISSN 0268-1161
Editore: Oxford University Press
DOI: 10.1093/humrep/dex286

Challenges in endometriosis miRNA studies — From tissue heterogeneity to disease specific miRNAs

Autori: Merli Saare, Kadri Rekker, Triin Laisk-Podar, Nilufer Rahmioglu, Krina Zondervan, Andres Salumets, Martin Götte, Maire Peters
Pubblicato in: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Numero 1863/9, 2017, Pagina/e 2282-2292, ISSN 0925-4439
Editore: Elsevier BV
DOI: 10.1016/j.bbadis.2017.06.018

High-throughput mRNA sequencing of stromal cells from endometriomas and endometrium

Autori: Kadri Rekker, Merli Saare, Elo Eriste, Tõnis Tasa, Viktorija Kukuškina, Anne Mari Roost, Kristi Anderson, Külli Samuel, Helle Karro, Andres Salumets, Maire Peters
Pubblicato in: Reproduction, Numero 154/1, 2017, Pagina/e 93-100, ISSN 1470-1626
Editore: Society for Reproduction and Fertility
DOI: 10.1530/rep-17-0092

TAC-seq: targeted DNA and RNA sequencing for precise biomarker molecule counting

Autori: Hindrek Teder, Mariann Koel, Priit Paluoja, Tatjana Jatsenko, Kadri Rekker, Triin Laisk-Podar, Viktorija Kukuškina, Agne Velthut-Meikas, Olga Fjodorova, Maire Peters, Juha Kere, Andres Salumets, Priit Palta, Kaarel Krjutškov
Pubblicato in: npj Genomic Medicine, Numero 3/1, 2018, ISSN 2056-7944
Editore: Springer Nature Limited
DOI: 10.1038/s41525-018-0072-5

Copy number variation analysis detects novel candidate genes involved in follicular growth and oocyte maturation in a cohort of premature ovarian failure cases

Autori: O. Tšuiko, M. Nõukas, O. Žilina, K. Hensen, J.S. Tapanainen, R. Mägi, M. Kals, P.A. Kivistik, K. Haller-Kikkatalo, A. Salumets, A. Kurg
Pubblicato in: Human Reproduction, Numero 31/8, 2016, Pagina/e 1913-1925, ISSN 0268-1161
Editore: Oxford University Press
DOI: 10.1093/humrep/dew142

Ovarian Physiology and GWAS: Biobanks, Biology, and Beyond

Autori: Triin Laisk-Podar, Cecilia M. Lindgren, Maire Peters, Juha S. Tapanainen, Cornelis B. Lambalk, Andres Salumets, Reedik Mägi
Pubblicato in: Trends in Endocrinology & Metabolism, Numero 27/7, 2016, Pagina/e 516-528, ISSN 1043-2760
Editore: Elsevier BV
DOI: 10.1016/j.tem.2016.04.011

Imprinted genes and imprinting control regions show predominant intermediate methylation in adult somatic tissues

Autori: Natalia Pervjakova, Silva Kasela, Andrew P Morris, Mart Kals, Andres Metspalu, Cecilia M Lindgren, Andres Salumets, Reedik Mägi
Pubblicato in: Epigenomics, Numero 8/6, 2016, Pagina/e 789-799, ISSN 1750-1911
Editore: Future Medicine Ltd.
DOI: 10.2217/epi.16.8

The influence of menstrual cycle and endometriosis on endometrial methylome

Autori: Merli Saare, Vijayachitra Modhukur, Marina Suhorutshenko, Balaji Rajashekar, Kadri Rekker, Deniss Sõritsa, Helle Karro, Pille Soplepmann, Andrei Sõritsa, Cecilia M. Lindgren, Nilufer Rahmioglu, Alexander Drong, Christian M. Becker, Krina T. Zondervan, Andres Salumets, Maire Peters
Pubblicato in: Clinical Epigenetics, Numero 8/1, 2016, ISSN 1868-7075
Editore: Springer Verlag
DOI: 10.1186/s13148-015-0168-z

C14orf132 gene is possibly related to extremely low birth weight

Autori: Airi Tiirats, Triin Viltrop, Margit Nõukas, Ene Reimann, Andres Salumets, Sulev Kõks
Pubblicato in: BMC Genetics, Numero 17/1, 2016, ISSN 1471-2156
Editore: BioMed Central
DOI: 10.1186/s12863-016-0439-5

Compartmentalized gene expression profiling of receptive endometrium reveals progesterone regulated ENPP3 is differentially expressed and secreted in glycosylated form

Autori: Nageswara Rao Boggavarapu, Sujata Lalitkumar, Vijay Joshua, Sergo Kasvandik, Andres Salumets, Parameswaran Grace Lalitkumar, Kristina Gemzell-Danielsson
Pubblicato in: Scientific Reports, Numero 6/1, 2016, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/srep33811

Globin mRNA reduction for whole-blood transcriptome sequencing

Autori: Kaarel Krjutškov, Mariann Koel, Anne Mari Roost, Shintaro Katayama, Elisabet Einarsdottir, Eeva-Mari Jouhilahti, Cilla Söderhäll, Ülle Jaakma, Mario Plaas, Liselotte Vesterlund, Hannes Lohi, Andres Salumets, Juha Kere
Pubblicato in: Scientific Reports, Numero 6/1, 2016, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/srep31584

Stanniocalcin-1 expression in normal human endometrium and dysregulation in endometriosis

Autori: Lusine Aghajanova, Signe Altmäe, Sergo Kasvandik, Andres Salumets, Anneli Stavreus-Evers, Linda C. Giudice
Pubblicato in: Fertility and Sterility, Numero 106/3, 2016, Pagina/e 681-691.e1, ISSN 0015-0282
Editore: Elsevier BV
DOI: 10.1016/j.fertnstert.2016.05.023

A novel hypothesis for histone-to-protamine transition in Bos taurus spermatozoa

Autori: Gerly Sillaste, Lauris Kaplinski, Riho Meier, Ülle Jaakma, Elo Eriste, Andres Salumets
Pubblicato in: Reproduction, Numero 153/3, 2016, Pagina/e 241-251, ISSN 1470-1626
Editore: Society for Reproduction and Fertility
DOI: 10.1530/REP-16-0441

Determination of biological activity of gonadotropins hCG and FSH by Förster resonance energy transfer based biosensors

Autori: Olga Mazina, Anni Allikalt, Juha S. Tapanainen, Andres Salumets, Ago Rinken
Pubblicato in: Scientific Reports, Numero 7, 2017, Pagina/e 42219, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/srep42219

Demographic associations for autoantibodies in disease-free individuals of a European population

Autori: Kadri Haller-Kikkatalo, Kristi Alnek, Andres Metspalu, Evelin Mihailov, Kaja Metsküla, Kalle Kisand, Heti Pisarev, Andres Salumets, Raivo Uibo
Pubblicato in: Scientific Reports, Numero 7, 2017, Pagina/e 44846, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/srep44846

Syndromic intellectual disability: A new phenotype caused by an aromatic amino acid decarboxylase gene (DDC) variant

Autori: Claudio Graziano, Anita Wischmeijer, Tommaso Pippucci, Carlo Fusco, Chiara Diquigiovanni, Margit Nõukas, Martin Sauk, Ants Kurg, Francesca Rivieri, Nenad Blau, Georg F. Hoffmann, Alka Chaubey, Charles E. Schwartz, Giovanni Romeo, Elena Bonora, Livia Garavelli, Marco Seri
Pubblicato in: Gene, Numero 03781119, 2015, Pagina/e 144-148, ISSN 0378-1119
Editore: Elsevier BV
DOI: 10.1016/j.gene.2015.01.026

The Human WBSCR22 Protein Is Involved in the Biogenesis of the 40S Ribosomal Subunits in Mammalian Cells

Autori: Kadri Õunap, Ly Käsper, Ants Kurg, Reet Kurg
Pubblicato in: PLoS ONE, Numero 19326203, 2013, Pagina/e e75686, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0075686

Monozygotic Twins with 17q21.31 Microdeletion Syndrome

Autori: Marketa Vlckova, Miroslava Hancarova, Jana Drabova, Zuzana Slamova, Monika Koudova, Renata Alanova, Katrin Mannik, Ants Kurg, Zdenek Sedlacek
Pubblicato in: Twin Research and Human Genetics, Numero 18324274, 2014, Pagina/e 405-410, ISSN 1832-4274
Editore: Australian Academic Press Pty Ltd.
DOI: 10.1017/thg.2014.29

The prevalence and phenotypic characteristics of spontaneous premature ovarian failure: a general population registry-based study

Autori: K. Haller-Kikkatalo, R. Uibo, A. Kurg, A. Salumets
Pubblicato in: Human Reproduction, Numero 02681161, 2015, Pagina/e 1229-1238, ISSN 0268-1161
Editore: Oxford University Press
DOI: 10.1093/humrep/dev021

EXCAVATOR: detecting copy number variants from whole-exome sequencing data

Autori: Alberto Magi, Lorenzo Tattini, Ingrid Cifola, Romina D’Aurizio, Matteo Benelli, Eleonora Mangano, Cristina Battaglia, Elena Bonora, Ants Kurg, Marco Seri, Pamela Magini, Betti Giusti, Giovanni Romeo, Tommaso Pippucci, Gianluca De Bellis, Rosanna Abbate, Gian Franco Gensini
Pubblicato in: Genome Biology, Numero 14656906, 2013, Pagina/e R120, ISSN 1465-6906
Editore: BioMed Central
DOI: 10.1186/gb-2013-14-10-r120

Somatic mosaicism for copy-neutral loss of heterozygosity and DNA copy number variations in the human genome

Autori: Olga Žilina, Marina Koltšina, Raivo Raid, Ants Kurg, Neeme Tõnisson, Andres Salumets
Pubblicato in: BMC Genomics, Numero 14712164, 2015, ISSN 1471-2164
Editore: BioMed Central
DOI: 10.1186/s12864-015-1916-3

Chromosomal microarray analysis as a first-tier clinical diagnostic test: Estonian experience

Autori: Olga Žilina, Rita Teek, Pille Tammur, Kati Kuuse, Maria Yakoreva, Eve Vaidla, Triin Mölter-Väär, Tiia Reimand, Ants Kurg, Katrin Õunap
Pubblicato in: Molecular Genetics & Genomic Medicine, Numero 23249269, 2014, Pagina/e 166-175, ISSN 2324-9269
Editore: Blackwell Publishing
DOI: 10.1002/mgg3.57

A patient with de novo 0.45 Mb deletion of 2p16.1: The role of BCL11A , PAPOLG , REL , and FLJ16341 in the 2p15-p16.1 microdeletion syndrome

Autori: Miroslava Hancarova, Martina Simandlova, Jana Drabova, Katrin Mannik, Ants Kurg, Zdenek Sedlacek
Pubblicato in: American Journal of Medical Genetics Part A, Numero 15524825, 2013, Pagina/e 865-870, ISSN 1552-4825
Editore: Wiley-Liss Inc
DOI: 10.1002/ajmg.a.35783

Patient with Dup(5)(q35.2-q35.3) reciprocal to the common Sotos syndrome deletion and review of the literature

Autori: Olga Žilina, Tiia Reimand, Pille Tammur, Vallo Tillmann, Ants Kurg, Katrin Õunap
Pubblicato in: European Journal of Medical Genetics, Numero 17697212, 2013, Pagina/e 202-206, ISSN 1769-7212
Editore: Elsevier BV
DOI: 10.1016/j.ejmg.2013.01.008

Circulating miR-200–family micro-RNAs have altered plasma levels in patients with endometriosis and vary with blood collection time

Autori: Kadri Rekker, Merli Saare, Anne Mari Roost, Tanel Kaart, Deniss Sõritsa, Helle Karro, Andrei Sõritsa, Carlos Simón, Andres Salumets, Maire Peters
Pubblicato in: Fertility and Sterility, Numero 00150282, 2015, Pagina/e 938-946.e2, ISSN 0015-0282
Editore: Elsevier BV
DOI: 10.1016/j.fertnstert.2015.06.029

Genetic variants associated with female reproductive ageing – potential markers for assessing ovarian function and ovarian stimulation outcome

Autori: Triin Laisk-Podar, Tanel Kaart, Maire Peters, Andres Salumets
Pubblicato in: Reproductive BioMedicine Online, Numero 14726483, 2015, Pagina/e 199-209, ISSN 1472-6483
Editore: Reproductive Healthcare Ltd
DOI: 10.1016/j.rbmo.2015.05.001

Expression Pattern and Localization Dynamics of Guanine Nucleotide Exchange Factor RIC8 during Mouse Oogenesis

Autori: Merly Saare, Sirje Lulla, Tambet Tõnissoo, Riho Meier, Keiu Kask, Katrin Ruisu, Alar Karis, Andres Salumets, Margus Pooga
Pubblicato in: PLOS ONE, Numero 19326203, 2015, Pagina/e e0129131, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0129131

Physical activity, fatness, educational level and snuff consumption as determinants of semen quality: findings of the ActiART study

Autori: Triin Pärn, Raúl Grau Ruiz, Theodora Kunovac Kallak, Jonatan R. Ruiz, Eva Davey, Julius Hreinsson, Kjell Wånggren, Andres Salumets, Michael Sjöström, Anneli Stavreus-Evers, Francisco B. Ortega, Signe Altmäe
Pubblicato in: Reproductive BioMedicine Online, Numero 14726483, 2015, Pagina/e 108-119, ISSN 1472-6483
Editore: Reproductive Healthcare Ltd
DOI: 10.1016/j.rbmo.2015.03.004

Complementary seminovaginal microbiome in couples

Autori: Reet Mändar, Margus Punab, Natalja Borovkova, Eleri Lapp, Riinu Kiiker, Paul Korrovits, Andres Metspalu, Kaarel Krjutškov, Hiie Nõlvak, Jens-Konrad Preem, Kristjan Oopkaup, Andres Salumets, Jaak Truu
Pubblicato in: Research in Microbiology, Numero 09232508, 2015, Pagina/e 440-447, ISSN 0923-2508
Editore: Elsevier BV
DOI: 10.1016/j.resmic.2015.03.009

Systemic oxidative stress could predict assisted reproductive technique outcome

Autori: A. Ahelik, R. Mändar, P. Korrovits, P. Karits, E. Talving, K. Rosenstein, M. Jaagura, A. Salumets, T. Kullisaar
Pubblicato in: Journal of Assisted Reproduction and Genetics, Numero 10580468, 2015, Pagina/e 699-704, ISSN 1058-0468
Editore: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s10815-015-0466-6

Genetic studies of body mass index yield new insights for obesity biology

Autori: Adam E. Locke, Bratati Kahali, Sonja I. Berndt, Anne E. Justice, Tune H. Pers, Felix R. Day, Corey Powell, Sailaja Vedantam, Martin L. Buchkovich, Jian Yang, Damien C. Croteau-Chonka, Tonu Esko, Tove Fall, Teresa Ferreira, Stefan Gustafsson, Zoltán Kutalik, Jian’an Luan, Reedik Mägi, Joshua C. Randall, Thomas W. Winkler, Andrew R. Wood, Tsegaselassie Workalemahu, Jessica D. Faul, Jennifer A. Smith, Jing Hua Zhao, Wei Zhao, Jin Chen, Rudolf Fehrmann, Åsa K. Hedman, Juha Karjalainen, Ellen M. Schmidt, Devin Absher, Najaf Amin, Denise Anderson, Marian Beekman, Jennifer L. Bolton, Jennifer L. Bragg-Gresham, Steven Buyske, Ayse Demirkan, Guohong Deng, Georg B. Ehret, Bjarke Feenstra, Mary F. Feitosa, Krista Fischer, Anuj Goel, Jian Gong, Anne U. Jackson, Stavroula Kanoni, Marcus E. Kleber, Kati Kristiansson, Unhee Lim, Vaneet Lotay, Massimo Mangino, Irene Mateo Leach, Carolina Medina-Gomez, Sarah E. Medland, Michael A. Nalls, Cameron D. Palmer, Dorota Pasko, Sonali Pechlivanis, Marjolein J. Peters, Inga Prokopenko, Dmitry Shungin, Alena Stančáková, Rona J. Strawbridge, Yun Ju Sung, Toshiko Tanaka, Alexander Teumer, Stella Trompet, Sander W. van der Laan, Jessica van Setten, Jana V. Van Vliet-Ostaptchouk, Zhaoming Wang, Loïc Yengo, Weihua Zhang, Aaron Isaacs, Eva Albrecht, Johan Ärnlöv, Gillian M. Arscott, Antony P. Attwood, Stefania Bandinelli, Amy Barrett, Isabelita N. Bas, Claire Bellis, Amanda J. Bennett, Christian Berne, Roza Blagieva, Matthias Blüher, Stefan Böhringer, Lori L. Bonnycastle, Yvonne Böttcher, Heather A. Boyd, Marcel Bruinenberg, Ida H. Caspersen, Yii-Der Ida Chen, Robert Clarke, E. Warwick Daw, Anton J. M. de Craen, Graciela Delgado, Maria Dimitriou, Alex S. F. Doney, Niina Eklund, Karol Estrada, Elodie Eury, Lasse Folkersen, Ross M. Fraser, Melissa E. Garcia, Frank Geller, Vilmantas Giedraitis, Bruna Gigante, Alan S. Go, Alain Golay, Alison H. Goodall, Scott D. Gordon, Mathias Gorski, Hans-Jörgen Grabe, Harald Grallert, Tanja B. Grammer, Jürgen Gräßler, Henrik Grönberg, Christopher J. Groves, Gaëlle Gusto, Jeffrey Haessler, Per Hall, Toomas Haller, Goran Hallmans, Catharina A. Hartman, Maija Hassinen, Caroline Hayward, Nancy L. Heard-Costa, Quinta Helmer, Christian Hengstenberg, Oddgeir Holmen, Jouke-Jan Hottenga, Alan L. James, Janina M. Jeff, Åsa Johansson, Jennifer Jolley, Thorhildur Juliusdottir, Leena Kinnunen, Wolfgang Koenig, Markku Koskenvuo, Wolfgang Kratzer, Jaana Laitinen, Claudia Lamina, Karin Leander, Nanette R. Lee, Peter Lichtner, Lars Lind, Jaana Lindström, Ken Sin Lo, Stéphane Lobbens, Roberto Lorbeer, Yingchang Lu, François Mach, Patrik K. E. Magnusson, Anubha Mahajan, Wendy L. McArdle, Stela McLachlan, Cristina Menni, Sigrun Merger, Evelin Mihailov, Lili Milani, Alireza Moayyeri, Keri L. Monda, Mario A. Morken, Antonella Mulas, Gabriele Müller, Martina Müller-Nurasyid, Arthur W. Musk, Ramaiah Nagaraja, Markus M. Nöthen, Ilja M. Nolte, Stefan Pilz, Nigel W. Rayner, Frida Renstrom, Rainer Rettig, Janina S. Ried, Stephan Ripke, Neil R. Robertson, Lynda M. Rose, Serena Sanna, Hubert Scharnagl, Salome Scholtens, Fredrick R. Schumacher, William R. Scott, Thomas Seufferlein, Jianxin Shi, Albert Vernon Smith, Joanna Smolonska, Alice V. Stanton, Valgerdur Steinthorsdottir, Kathleen Stirrups, Heather M. Stringham, Johan Sundström, Morris A. Swertz, Amy J. Swift, Ann-Christine Syvänen, Sian-Tsung Tan, Bamidele O. Tayo, Barbara Thorand, Gudmar Thorleifsson, Jonathan P. Tyrer, Hae-Won Uh, Liesbeth Vandenput, Frank C. Verhulst, Sita H. Vermeulen, Niek Verweij, Judith M. Vonk, Lindsay L. Waite, Helen R. Warren, Dawn Waterworth, Michael N. Weedon, Lynne R. Wilkens, Christina Willenborg, Tom Wilsgaard, Mary K. Wojczynski, Andrew Wong, Alan F. Wright, Qunyuan Zhang, Eoin P. Brennan, Murim Choi, Zari Dastani, Alexander W. Drong, Per Eriksson, Anders Franco-Cereceda, Jesper R. Gådin, Ali G. Gharavi, Michael E. Goddard, Robert E. Handsaker, Jinyan Huang, Fredrik Karpe, Sekar Kathiresa
Pubblicato in: Nature, Numero 00280836, 2015, Pagina/e 197-206, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/nature14177

New genetic loci link adipose and insulin biology to body fat distribution

Autori: Dmitry Shungin, Thomas W. Winkler, Damien C. Croteau-Chonka, Teresa Ferreira, Adam E. Locke, Reedik Mägi, Rona J. Strawbridge, Tune H. Pers, Krista Fischer, Anne E. Justice, Tsegaselassie Workalemahu, Joseph M. W. Wu, Martin L. Buchkovich, Nancy L. Heard-Costa, Tamara S. Roman, Alexander W. Drong, Ci Song, Stefan Gustafsson, Felix R. Day, Tonu Esko, Tove Fall, Zoltán Kutalik, Jian’an Luan, Joshua C. Randall, André Scherag, Sailaja Vedantam, Andrew R. Wood, Jin Chen, Rudolf Fehrmann, Juha Karjalainen, Bratati Kahali, Ching-Ti Liu, Ellen M. Schmidt, Devin Absher, Najaf Amin, Denise Anderson, Marian Beekman, Jennifer L. Bragg-Gresham, Steven Buyske, Ayse Demirkan, Georg B. Ehret, Mary F. Feitosa, Anuj Goel, Anne U. Jackson, Toby Johnson, Marcus E. Kleber, Kati Kristiansson, Massimo Mangino, Irene Mateo Leach, Carolina Medina-Gomez, Cameron D. Palmer, Dorota Pasko, Sonali Pechlivanis, Marjolein J. Peters, Inga Prokopenko, Alena Stančáková, Yun Ju Sung, Toshiko Tanaka, Alexander Teumer, Jana V. Van Vliet-Ostaptchouk, Loïc Yengo, Weihua Zhang, Eva Albrecht, Johan Ärnlöv, Gillian M. Arscott, Stefania Bandinelli, Amy Barrett, Claire Bellis, Amanda J. Bennett, Christian Berne, Matthias Blüher, Stefan Böhringer, Fabrice Bonnet, Yvonne Böttcher, Marcel Bruinenberg, Delia B. Carba, Ida H. Caspersen, Robert Clarke, E. Warwick Daw, Joris Deelen, Ewa Deelman, Graciela Delgado, Alex S. F. Doney, Niina Eklund, Michael R. Erdos, Karol Estrada, Elodie Eury, Nele Friedrich, Melissa E. Garcia, Vilmantas Giedraitis, Bruna Gigante, Alan S. Go, Alain Golay, Harald Grallert, Tanja B. Grammer, Jürgen Gräßler, Jagvir Grewal, Christopher J. Groves, Toomas Haller, Goran Hallmans, Catharina A. Hartman, Maija Hassinen, Caroline Hayward, Kauko Heikkilä, Karl-Heinz Herzig, Quinta Helmer, Hans L. Hillege, Oddgeir Holmen, Steven C. Hunt, Aaron Isaacs, Till Ittermann, Alan L. James, Ingegerd Johansson, Thorhildur Juliusdottir, Ioanna-Panagiota Kalafati, Leena Kinnunen, Wolfgang Koenig, Ishminder K. Kooner, Wolfgang Kratzer, Claudia Lamina, Karin Leander, Nanette R. Lee, Peter Lichtner, Lars Lind, Jaana Lindström, Stéphane Lobbens, Mattias Lorentzon, François Mach, Patrik K. E. Magnusson, Anubha Mahajan, Wendy L. McArdle, Cristina Menni, Sigrun Merger, Evelin Mihailov, Lili Milani, Rebecca Mills, Alireza Moayyeri, Keri L. Monda, Simon P. Mooijaart, Thomas W. Mühleisen, Antonella Mulas, Gabriele Müller, Martina Müller-Nurasyid, Ramaiah Nagaraja, Michael A. Nalls, Narisu Narisu, Nicola Glorioso, Ilja M. Nolte, Matthias Olden, Nigel W. Rayner, Frida Renstrom, Janina S. Ried, Neil R. Robertson, Lynda M. Rose, Serena Sanna, Hubert Scharnagl, Salome Scholtens, Bengt Sennblad, Thomas Seufferlein, Colleen M. Sitlani, Albert Vernon Smith, Kathleen Stirrups, Heather M. Stringham, Johan Sundström, Morris A. Swertz, Amy J. Swift, Ann-Christine Syvänen, Bamidele O. Tayo, Barbara Thorand, Gudmar Thorleifsson, Andreas Tomaschitz, Chiara Troffa, Floor V. A. van Oort, Niek Verweij, Judith M. Vonk, Lindsay L. Waite, Roman Wennauer, Tom Wilsgaard, Mary K. Wojczynski, Andrew Wong, Qunyuan Zhang, Jing Hua Zhao, Eoin P. Brennan, Murim Choi, Per Eriksson, Lasse Folkersen, Anders Franco-Cereceda, Ali G. Gharavi, Åsa K. Hedman, Marie-France Hivert, Jinyan Huang, Stavroula Kanoni, Fredrik Karpe, Sarah Keildson, Krzysztof Kiryluk, Liming Liang, Richard P. Lifton, Baoshan Ma, Amy J. McKnight, Ruth McPherson, Andres Metspalu, Josine L. Min, Miriam F. Moffatt, Grant W. Montgomery, Joanne M. Murabito, George Nicholson, Dale R. Nyholt, Christian Olsson, John R. B. Perry, Eva Reinmaa, Rany M. Salem, Niina Sandholm, Eric E. Schadt, Robert A. Scott, Lisette Stolk, Edgar E. Vallejo, Harm-Jan Westra, Krina T. Zondervan, Philippe Amouyel, Dominique Arveiler, Stephan J. L. Bakker, John Beilby, Richard N. Bergman, John Blangero, Morris J. Brown, Michel Burnier, Harry Campbell, Aravinda Chakravarti, Peter S. Chines, Simone Claudi-Boehm, Francis S. Collins, Dana C. Crawford, Jo
Pubblicato in: Nature, Numero 00280836, 2015, Pagina/e 187-196, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/nature14132

Bovine sperm plasma membrane proteomics through biotinylation and subcellular enrichment

Autori: Sergo Kasvandik, Gerly Sillaste, Agne Velthut-Meikas, Aavo-Valdur Mikelsaar, Triin Hallap, Peeter Padrik, Tanel Tenson, Ülle Jaakma, Sulev Kõks, Andres Salumets
Pubblicato in: PROTEOMICS, Numero 16159853, 2015, Pagina/e 1906-1920, ISSN 1615-9853
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/pmic.201400297

Using RNA sequencing for identifying gene imprinting and random monoallelic expression in human placenta

Autori: Tauno Metsalu, Triin Viltrop, Airi Tiirats, Balaji Rajashekar, Ene Reimann, Sulev Kõks, Kristiina Rull, Lili Milani, Ganesh Acharya, Purusotam Basnet, Jaak Vilo, Reedik Mägi, Andres Metspalu, Maire Peters, Kadri Haller-Kikkatalo, Andres Salumets
Pubblicato in: Epigenetics, Numero 15592294, 2014, Pagina/e 1397-1409, ISSN 1559-2294
Editore: Landes Bioscience
DOI: 10.4161/15592294.2014.970052

High-Throughput Sequencing Approach Uncovers the miRNome of Peritoneal Endometriotic Lesions and Adjacent Healthy Tissues

Autori: Merli Saare, Kadri Rekker, Triin Laisk-Podar, Deniss Sõritsa, Anne Mari Roost, Jaak Simm, Agne Velthut-Meikas, Külli Samuel, Tauno Metsalu, Helle Karro, Andrei Sõritsa, Andres Salumets, Maire Peters
Pubblicato in: PLoS ONE, Numero 19326203, 2014, Pagina/e e112630, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0112630

Pregnancy Rate in Endometriosis Patients according to the Severity of the Disease after Using a Combined Approach of Laparoscopy, GnRH Agonist Treatment and in vitro Fertilization

Autori: Deniss Sõritsa, Merli Saare, Triin Laisk-Podar, Maire Peters, Andrei Sõritsa, Kadri Matt, Helle Karro, Andres Salumets
Pubblicato in: Gynecologic and Obstetric Investigation, Numero 03787346, 2015, Pagina/e 34-39, ISSN 0378-7346
Editore: S. Karger AG
DOI: 10.1159/000365329

Folic acid supplementation and methylenetetrahydrofolate reductase (MTHFR) gene variations in relation to in vitro fertilization pregnancy outcome

Autori: Tiina Murto, Theodora K. Kallak, Annica Hoas, Signe Altmäe, Andres Salumets, Torbjörn K. Nilsson, Agneta Skoog Svanberg, Kjell Wånggren, Agneta Yngve, Anneli Stavreus-Evers
Pubblicato in: Acta Obstetricia et Gynecologica Scandinavica, Numero 00016349, 2015, Pagina/e 65-71, ISSN 0001-6349
Editore: Wiley-Blackwell
DOI: 10.1111/aogs.12522

Autoimmune Activation toward Embryo Implantation is Rare in Immune-Privileged Human Endometrium

Autori: Kadri Haller-Kikkatalo, Aili Tagoma, Raivo Uibo, Andres Salumets, Signe Altmäe
Pubblicato in: Seminars in Reproductive Medicine, Numero 15268004, 2014, Pagina/e 376-384, ISSN 1526-8004
Editore: Thieme Medical Publishers
DOI: 10.1055/s-0034-1376356

Sequencing and annotated analysis of full genome of Holstein breed bull

Autori: Sulev Kõks, Ene Reimann, Rutt Lilleoja, Freddy Lättekivi, Andres Salumets, Paula Reemann, Ülle Jaakma
Pubblicato in: Mammalian Genome, Numero 09388990, 2014, Pagina/e 363-373, ISSN 0938-8990
Editore: Springer Verlag
DOI: 10.1007/s00335-014-9511-5

Folic acid supplementation and IVF pregnancy outcome in women with unexplained infertility

Autori: T. Murto, A. Skoog Svanberg, A. Yngve, T.K. Nilsson, S. Altmäe, K. Wånggren, A. Salumets, A. Stavreus-Evers
Pubblicato in: Reproductive BioMedicine Online, Numero 14726483, 2014, Pagina/e 766-772, ISSN 1472-6483
Editore: Reproductive Healthcare Ltd
DOI: 10.1016/j.rbmo.2014.01.017

DNA mismatch repair gene MSH6 implicated in determining age at natural menopause

Autori: J. R. B. Perry, Y.-H. Hsu, D. I. Chasman, A. D. Johnson, C. Elks, E. Albrecht, I. L. Andrulis, J. Beesley, G. S. Berenson, S. Bergmann, S. E. Bojesen, M. K. Bolla, J. Brown, J. E. Buring, H. Campbell, J. Chang-Claude, G. Chenevix-Trench, T. Corre, F. J. Couch, A. Cox, K. Czene, A. P. D'adamo, G. Davies, I. J. Deary, J. Dennis, D. F. Easton, E. G. Engelhardt, J. G. Eriksson, T. Esko, P. A. Fasching, J. D. Figueroa, H. Flyger, A. Fraser, M. Garcia-Closas, P. Gasparini, C. Gieger, G. Giles, P. Guenel, S. Hagg, P. Hall, C. Hayward, J. Hopper, E. Ingelsson, S. L. R. Kardia, K. Kasiman, J. A. Knight, J. Lahti, D. A. Lawlor, P. K. E. Magnusson, S. Margolin, J. A. Marsh, A. Metspalu, J. E. Olson, C. E. Pennell, O. Polasek, I. Rahman, P. M. Ridker, A. Robino, I. Rudan, A. Rudolph, A. Salumets, M. K. Schmidt, M. J. Schoemaker, E. N. Smith, J. A. Smith, M. Southey, D. Stockl, A. J. Swerdlow, D. J. Thompson, T. Truong, S. Ulivi, M. Waldenberger, Q. Wang, S. Wild, J. F. Wilson, A. F. Wright, L. Zgaga, K. K. Ong, J. M. Murabito, D. Karasik, A. Murray
Pubblicato in: Human Molecular Genetics, Numero 09646906, 2014, Pagina/e 2490-2497, ISSN 0964-6906
Editore: Oxford University Press
DOI: 10.1093/hmg/ddt620

Circulating microRNA Profile throughout the Menstrual Cycle

Autori: Kadri Rekker, Merli Saare, Anne Mari Roost, Andres Salumets, Maire Peters
Pubblicato in: PLoS ONE, Numero 19326203, 2013, Pagina/e e81166, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0081166

Comparison of serum exosome isolation methods for microRNA profiling

Autori: Kadri Rekker, Merli Saare, Anne Mari Roost, Anna-Liisa Kubo, Natasa Zarovni, Antonio Chiesi, Andres Salumets, Maire Peters
Pubblicato in: Clinical Biochemistry, Numero 00099120, 2014, Pagina/e 135-138, ISSN 0009-9120
Editore: Elsevier BV
DOI: 10.1016/j.clinbiochem.2013.10.020

Guidelines for the design, analysis and interpretation of 'omics' data: focus on human endometrium

Autori: S. Altmae, F. J. Esteban, A. Stavreus-Evers, C. Simon, L. Giudice, B. A. Lessey, J. A. Horcajadas, N. S. Macklon, T. D'Hooghe, C. Campoy, B. C. Fauser, L. A. Salamonsen, A. Salumets
Pubblicato in: Human Reproduction Update, Numero 13554786, 2013, Pagina/e 12-28, ISSN 1355-4786
Editore: Oxford University Press
DOI: 10.1093/humupd/dmt048

Sequencing and annotated analysis of the Holstein cow genome

Autori: Sulev Kõks, Rutt Lilleoja, Ene Reimann, Andres Salumets, Paula Reemann, Ülle Jaakma
Pubblicato in: Mammalian Genome, Numero 09388990, 2013, Pagina/e 309-321, ISSN 0938-8990
Editore: Springer Verlag
DOI: 10.1007/s00335-013-9464-0

Changes in the Transcriptome of the Human Endometrial Ishikawa Cancer Cell Line Induced by Estrogen, Progesterone, Tamoxifen, and Mifepristone (RU486) as Detected by RNA-Sequencing

Autori: Karin Tamm-Rosenstein, Jaak Simm, Marina Suhorutshenko, Andres Salumets, Madis Metsis
Pubblicato in: PLoS ONE, Numero 19326203, 2013, Pagina/e e68907, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0068907

Tissue-specific mitochondrial heteroplasmy at position 16,093 within the same individual

Autori: Kaarel Krjutškov, Marina Koltšina, Kelli Grand, Urmo Võsa, Martin Sauk, Neeme Tõnisson, Andres Salumets
Pubblicato in: Current Genetics, Numero 01728083, 2014, Pagina/e 11-16, ISSN 0172-8083
Editore: Springer Verlag
DOI: 10.1007/s00294-013-0398-6

Research Resource: Small RNA-seq of Human Granulosa Cells Reveals miRNAs in FSHR and Aromatase Genes

Autori: Agne Velthut-Meikas, Jaak Simm, Timo Tuuri, Juha S. Tapanainen, Madis Metsis, Andres Salumets
Pubblicato in: Molecular Endocrinology, Numero 08888809, 2013, Pagina/e 1128-1141, ISSN 0888-8809
Editore: The Endocrine Society
DOI: 10.1210/me.2013-1058

Elevated blood plasma antioxidant status is favourable for achieving IVF/ICSI pregnancy

Autori: Agne Velthut, Mihkel Zilmer, Kersti Zilmer, Tanel Kaart, Helle Karro, Andres Salumets
Pubblicato in: Reproductive BioMedicine Online, Numero 14726483, 2013, Pagina/e 345-352, ISSN 1472-6483
Editore: Reproductive Healthcare Ltd
DOI: 10.1016/j.rbmo.2012.12.012

Characterization of the Vaginal Micro- and Mycobiome in Asymptomatic Reproductive-Age Estonian Women

Autori: Tiina Drell, Triin Lillsaar, Lea Tummeleht, Jaak Simm, Anu Aaspõllu, Edda Väin, Ivo Saarma, Andres Salumets, Gilbert G. G. Donders, Madis Metsis
Pubblicato in: PLoS ONE, Numero 19326203, 2013, Pagina/e e54379, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0054379

A genome-wide association study of early menopause and the combined impact of identified variants

Autori: J. R. B. Perry, T. Corre, T. Esko, D. I. Chasman, K. Fischer, N. Franceschini, C. He, Z. Kutalik, M. Mangino, L. M. Rose, A. Vernon Smith, L. Stolk, P. Sulem, M. N. Weedon, W. V. Zhuang, A. Arnold, A. Ashworth, S. Bergmann, J. E. Buring, A. Burri, C. Chen, M. C. Cornelis, D. J. Couper, M. O. Goodarzi, V. Gudnason, T. Harris, A. Hofman, M. Jones, P. Kraft, L. Launer, J. S. E. Laven, G. Li, B. McKnight, C. Masciullo, L. Milani, N. Orr, B. M. Psaty, P. M. Ridker, F. Rivadeneira, C. Sala, A. Salumets, M. Schoemaker, M. Traglia, G. Waeber, S. J. Chanock, E. W. Demerath, M. Garcia, S. E. Hankinson, F. B. Hu, D. J. Hunter, K. L. Lunetta, A. Metspalu, G. W. Montgomery, J. M. Murabito, A. B. Newman, K. K. Ong, T. D. Spector, K. Stefansson, A. J. Swerdlow, U. Thorsteinsdottir, R. M. Van Dam, A. G. Uitterlinden, J. A. Visser, P. Vollenweider, D. Toniolo, A. Murray
Pubblicato in: Human Molecular Genetics, Numero 09646906, 2013, Pagina/e 1465-1472, ISSN 0964-6906
Editore: Oxford University Press
DOI: 10.1093/hmg/dds551

MicroRNAs miR-30b, miR-30d, and miR-494 Regulate Human Endometrial Receptivity

Autori: S. Altmae, J. A. Martinez-Conejero, F. J. Esteban, M. Ruiz-Alonso, A. Stavreus-Evers, J. A. Horcajadas, A. Salumets
Pubblicato in: Reproductive Sciences, Numero 19337191, 2013, Pagina/e 308-317, ISSN 1933-7191
Editore: SAGE Publications
DOI: 10.1177/1933719112453507

Corrigendum: Rare coding variants and X-linked loci associated with age at menarche

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Editore: Nature Publishing Group
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Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

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Rare coding variants and X-linked loci associated with age at menarche

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Using Genetic Variants to Assess the Relationship Between Circulating Lipids and Type 2 Diabetes

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Editore: American Diabetes Association
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Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

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Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu

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Pubblicato in: Birth, Numero 07307659, 2015, Pagina/e 48-55, ISSN 0730-7659
Editore: Blackwell Publishing Inc.
DOI: 10.1111/birt.12147

Prevalence of experienced abuse in healthcare and associated obstetric characteristics in six European countries

Autori: Mirjam Lukasse, Anne-Mette Schroll, Helle Karro, Berit Schei, Thora Steingrimsdottir, An-Sofie Van Parys, Elsa Lena Ryding, Ann Tabor
Pubblicato in: Acta Obstetricia et Gynecologica Scandinavica, Numero 00016349, 2015, Pagina/e 508-517, ISSN 0001-6349
Editore: Wiley-Blackwell
DOI: 10.1111/aogs.12593

Abortion trends from 1996 to 2011 in Estonia: special emphasis on repeat abortion

Autori: Made Laanpere, Inge Ringmets, Kai Part, Kärt Allvee, Piret Veerus, Helle Karro
Pubblicato in: BMC Women's Health, Numero 14726874, 2014, Pagina/e 81, ISSN 1472-6874
Editore: BioMed Central
DOI: 10.1186/1472-6874-14-81

Prevalence of emotional, physical and sexual abuse among pregnant women in six European countries

Autori: Mirjam Lukasse, Anne-Mette Schroll, Elsa Lena Ryding, Jacquelyn Campbell, Helle Karro, Hildur Kristjansdottir, Made Laanpere, Thora Steingrimsdottir, Ann Tabor, Marleen Temmerman, An-Sofie Van Parys, Anne-Marie Wangel, Berit Schei
Pubblicato in: Acta Obstetricia et Gynecologica Scandinavica, Numero 00016349, 2014, Pagina/e 669-677, ISSN 0001-6349
Editore: Wiley-Blackwell
DOI: 10.1111/aogs.12392

A History of Abuse and Operative Delivery – Results from a European Multi-Country Cohort Study

Autori: Berit Schei, Mirjam Lukasse, Elsa Lena Ryding, Jacquelyn Campbell, Helle Karro, Hildur Kristjansdottir, Made Laanpere, Anne-Mette Schroll, Ann Tabor, Marleen Temmerman, An-Sofie Van Parys, Anne-Marie Wangel, Thora Steingrimsdottir
Pubblicato in: PLoS ONE, Numero 19326203, 2014, Pagina/e e87579, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0087579

Teenage pregnancies in the European Union in the context of legislation and youth sexual and reproductive health services

Autori: Kai Part, Caroline Moreau, Serena Donati, Mika Gissler, Inês Fronteira, Helle Karro
Pubblicato in: Acta Obstetricia et Gynecologica Scandinavica, Numero 00016349, 2013, Pagina/e 1395-1406, ISSN 0001-6349
Editore: Wiley-Blackwell
DOI: 10.1111/aogs.12253

Intimate partner violence and sexual health outcomes: a population-based study among 16-44-year-old women in Estonia

Autori: M. Laanpere, I. Ringmets, K. Part, H. Karro
Pubblicato in: The European Journal of Public Health, Numero 11011262, 2013, Pagina/e 688-693, ISSN 1101-1262
Editore: Oxford University Press
DOI: 10.1093/eurpub/cks144

Genomic imprinting in complex traits

Autori: Pervjakova, Natalja
Pubblicato in: 2018, ISBN 978-9949-77-735-8
Editore: University of Tartu Press

Unravelling chromosomal instability in mammalian preimplantation embryos using single-cell genomics

Autori: Tšuiko, Olga
Pubblicato in: 2018, ISBN 978-9949-77-862-1
Editore: University of Tartu Press

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