Deliverables Documents, reports (14) Report from visits to the international conferences Report from visits to the international conferences First reports. Reports on the participation in promotional and information events and focus meeting with agenda of events and analysis of added value for potential increase of research in IGHZ PAN Reports on the participation in promotional and information events and focus meeting with agenda of events and analysis of added value for potential increase of research in IGHZ PAN Report of the seminar for SME with agenda, proceedings, conclusions, lists of participants, further actions /implications for IGHZ PAN Report of the seminar for SME with agenda, proceedings, conclusions, lists of participants, further actions /implications for IGHZ PAN Report of the workshop on comparative experimental embryology methods with agenda, proceedings, conclusions, lists of participants, further actions/implications for IGHZ PAN and involved participants Report of the workshop on comparative experimental embryology methods with agenda, proceedings, conclusions, lists of participants, further actions/implications for IGHZ PAN and involved participants Cooperation agreements with partners Cooperation agreements with partners Second reports. Reports on the participation in promotional and information events and focus meeting with agenda of events and analysis of added value for potential increase of research in IGHZ PAN Reports on the participation in promotional and information events and focus meeting with agenda of events and analysis of added value for potential increase of research in IGHZ PAN Report of the Conference: What is known about offspring obtained by Assisted Reproduction Technologies with agenda, proceedings, conclusions, lists of participants, further actions and implications for IGHZ PAN and partners involved Report of the Conference: What is known about offspring obtained by Assisted Reproduction Technologies with agenda, proceedings, conclusions, lists of participants, further actions and implications for IGHZ PAN and partners involved Report of the workshop on oocyte maturation and fertilization and embryo culture methods in large animal models with agenda, proceedings, conclusions, lists of participants, further actions/implications for IGHZ PAN and partners involved Report of the workshop on oocyte maturation and fertilization and embryo culture methods in large animal models with agenda, proceedings, conclusions, lists of participants, further actions/implications for IGHZ PAN and partners involved Joint report on summer school together with UJ Joint report on summer school together with UJ Report of the workshop on oocytes and embryo manipulations with agenda, proceedings, conclusions, lists of participants, further actions/implications for IGHZ PAN and partners involved Report of the workshop on oocytes and embryo manipulations with agenda, proceedings, conclusions, lists of participants, further actions/implications for IGHZ PAN and partners involved Report of the conference on ART: Long-Term Perspectives, with agenda, proceedings, conclusions, lists of participants, further actions/implications for IGHZ PAN Report of the conference on ART: Long-Term Perspectives, with agenda, proceedings, conclusions, lists of participants, further actions/implications for IGHZ PAN Joint report (with WP 2 task 2.2) on summer school in Embryo valuation and Molecular Biology Tools in ART with agenda, proceedings, conclusions, lists of participants, further actions/implications for IGHZ PAN and partners involved Joint report (with WP 2 task 2.2) on summer school in Embryo valuation and Molecular Biology Tools in ART with agenda, proceedings, conclusions, lists of participants, further actions/implications for IGHZ PAN and partners involved Report with the copies of scientific papers and proceedings published in connection to the Twinning Research Group activities Report with the copies of scientific papers and proceedings published in connection to the Twinning Research Group activities Statement that the report has been completed Statement that the report has been completed Websites, patent fillings, videos etc. (3) Operational website of the project Operational website of the project Promotional brochure of the project Promotional brochure of the project Promotional leaflet of the project Promotional leaflet of the project Publications Peer reviewed articles (44) Developmental peculiarities in placentae of ovine uniparental conceptuses Author(s): Roberta Arena, Federica Zacchini, Paola Toschi, Luca Palazzese, Marta Czernik, Grażyna Ewa Ptak Published in: PLOS ONE, Issue 12/11, 2017, Page(s) e0188278, ISSN 1932-6203 Publisher: Public Library of Science DOI: 10.1371/journal.pone.0188278 Polychlorinated biphenyls (PCBs) alter DNA methylation and genomic integrity of sheep fetal cells in a simplified in vitro model of pregnancy exposure Author(s): Debora A. Anzalone, Silvestre Sampino, Marta Czernik, Domenico Iuso, Grazyna E. Ptak Published in: Toxicology in Vitro, Issue 46, 2018, Page(s) 39-46, ISSN 0887-2333 Publisher: Elsevier BV DOI: 10.1016/j.tiv.2017.09.017 Development to term of sheep embryos reconstructed after inner cell mass/trophoblast exchange Author(s): Pasqualino LOI, Cesare GALLI, Giovanna LAZZARI, Kazutsugu MATSUKAWA, Josef FULKA, Jr, Frank GOERITZ, Thomas B. HILDEBRANDT Published in: Journal of Reproduction and Development, Issue 64/2, 2018, Page(s) 187-191, ISSN 0916-8818 Publisher: IPEC Inc. DOI: 10.1262/jrd.2017-109 Exploring dry storage as an alternative biobanking strategy inspired by Nature Author(s): Joseph Saragusty, Pasqualino Loi Published in: Theriogenology, Issue 126, 2019, Page(s) 17-27, ISSN 0093-691X Publisher: Elsevier BV DOI: 10.1016/j.theriogenology.2018.11.027 DNA fragmentation in epididymal freeze-dried ram spermatozoa impairs embryo development Author(s): Luca PALAZZESE, Jaime GOSÁLVEZ, Debora A. ANZALONE, Pasqualino LOI, Joseph SARAGUSTY Published in: Journal of Reproduction and Development, Issue 64/5, 2018, Page(s) 393-400, ISSN 0916-8818 Publisher: IPEC Inc. DOI: 10.1262/jrd.2018-033 Embryos and embryonic stem cells from the white rhinoceros Author(s): Thomas B. Hildebrandt, Robert Hermes, Silvia Colleoni, Sebastian Diecke, Susanne Holtze, Marilyn B. Renfree, Jan Stejskal, Katsuhiko Hayashi, Micha Drukker, Pasqualino Loi, Frank Göritz, Giovanna Lazzari, Cesare Galli Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-018-04959-2 Nuclear quiescence and histone hyper-acetylation jointly improve protamine-mediated nuclear remodeling in sheep fibroblasts Author(s): Luca Palazzese, Marta Czernik, Domenico Iuso, Paola Toschi, Pasqualino Loi Published in: PLOS ONE, Issue 13/3, 2018, Page(s) e0193954, ISSN 1932-6203 Publisher: Public Library of Science DOI: 10.1371/journal.pone.0193954 Allele-specific methylation of imprinted genes in fetal cord blood is influenced by cis-acting genetic variants and parental factors Author(s): Ramya Potabattula, Marcus Dittrich, Julia Böck, Larissa Haertle, Tobias Müller, Thomas Hahn, Martin Schorsch, Nady El Hajj, Thomas Haaf Published in: Epigenomics, Issue 10/10, 2018, Page(s) 1315-1326, ISSN 1750-1911 Publisher: Future Medicine Ltd. DOI: 10.2217/epi-2018-0059 Gene expression and epigenetic aberrations in F1-placentas fathered by obese males Author(s): Megan Mitchell, Reiner Strick, Pamela L. Strissel, Ralf Dittrich, Nicole O. McPherson, Michelle Lane, Galyna Pliushch, Ramya Potabattula, Thomas Haaf, Nady El Hajj Published in: Molecular Reproduction and Development, Issue 84/4, 2017, Page(s) 316-328, ISSN 1040-452X Publisher: John Wiley & Sons Inc. DOI: 10.1002/mrd.22784 Epigenetic signatures of gestational diabetes mellitus on cord blood methylation Author(s): Larissa Haertle, Nady El Hajj, Marcus Dittrich, Tobias Müller, Indrajit Nanda, Harald Lehnen, Thomas Haaf Published in: Clinical Epigenetics, Issue 9/1, 2017, ISSN 1868-7075 Publisher: Springer Verlag DOI: 10.1186/s13148-017-0329-3 Prenatal and postnatal experiences associated with epigenetic changes in the adult mouse brain Author(s): Felix Mattern, Antonia Post, Franziska Solger, Aet O’Leary, David A. Slattery, Andreas Reif, Thomas Haaf Published in: Behavioural Brain Research, Issue 359, 2019, Page(s) 143-148, ISSN 0166-4328 Publisher: Elsevier BV DOI: 10.1016/j.bbr.2018.10.037 Embryo biopsy and development: the known and the unknown Author(s): Federica Zacchini, Roberta Arena, Adam Abramik, Grazyna E Ptak Published in: Reproduction, Issue 154/5, 2017, Page(s) R143-R148, ISSN 1470-1626 Publisher: Society for Reproduction and Fertility DOI: 10.1530/rep-17-0431 A Protein Preparation Method for the High-throughput Identification of Proteins Interacting with a Nuclear Cofactor Using LC-MS/MS Analysis Author(s): Megumi Tsuchiya, M. Rezaul Karim, Taro Matsumoto, Hidesato Ogawa, Hiroaki Taniguchi Published in: Journal of Visualized Experiments, Issue 119, 2017, ISSN 1940-087X Publisher: MYJoVE Corporation DOI: 10.3791/55077 Manipulating Living Cells to Construct Stable 3D Cellular Assembly Without Artificial Scaffold Author(s): Takehiro Yamazaki, Hiroaki Taniguchi, Shoto Tsuji, Shiho Sato, Takahiro Kenmotsu, Kenichi Yoshikawa, Koichiro Sadakane Published in: Journal of Visualized Experiments, Issue 140, 2018, ISSN 1940-087X Publisher: MYJoVE Corporation DOI: 10.3791/57815 Manipulating Living Cells to Construct a 3D Single-Cell Assembly without an Artificial Scaffold Author(s): Aoi Yoshida, Shoto Tsuji, Hiroaki Taniguchi, Takahiro Kenmotsu, Koichiro Sadakane, Kenichi Yoshikawa Published in: Polymers, Issue 9/12, 2017, Page(s) 319, ISSN 2073-4360 Publisher: MDPI DOI: 10.3390/polym9080319 Diabetes Mellitus and Male Aging: Pharmacotherapeutics and Clinical Implications Author(s): Swathi Putta, Ilaria Peluso, Nagendra Sastry Yarla, Eswar Kumar Kilari, Anupam Bishayee, Da-Yong Lu, George E. Barreto, Ghulam Md Ashraf, Luciana Scotti, Marcus T. Scotti, Rajeev K. Singla, Thonos Alexiou, Atanas G. Atanasov, Vadim V. Tarasov, P. Veera Bramhachari, Sarat Babu Imandi, Madhuri Chintala, Bechan Sharma, Marcella Reale, Rosanna Filosa, Gjumrakch Aliev, Mohammad Amjad Kamal Published in: Current Pharmaceutical Design, Issue 23/30, 2017, ISSN 1381-6128 Publisher: Bentham Science Publishers DOI: 10.2174/1381612823666170823103830 64 Impaired Post-Implantation Development Following Blastomere Biopsy is Associated with Placental Hypomethylation Author(s): F. Zacchini, M. Ogluska, R. Arena, G. E. Ptak Published in: Reproduction, Fertility and Development, Issue 30/1, 2018, Page(s) 171, ISSN 1031-3613 Publisher: Commonwealth Scientific and Industrial Research Organization Publishing DOI: 10.1071/rdv30n1ab64 Evidence of Placental Autophagy during Early Pregnancy after Transfer of In Vitro Produced (IVP) Sheep Embryos Author(s): Paola Toschi, Marta Czernik, Federica Zacchini, Antonella Fidanza, Pasqualino Loi, Grażyna Ewa Ptak Published in: PLOS ONE, Issue 11/6, 2016, Page(s) e0157594, ISSN 1932-6203 Publisher: Public Library of Science DOI: 10.1371/journal.pone.0157594 Cobalamin supplementation during in vitro maturation improves developmental competence of sheep oocytes Author(s): Federica Zacchini, Paola Toschi, Grazyna Ewa Ptak Published in: Theriogenology, Issue 93, 2017, Page(s) 55-61, ISSN 0093-691X Publisher: Elsevier BV DOI: 10.1016/j.theriogenology.2017.01.035 Deregulated Expression of Mitochondrial Proteins Mfn2 and Bcnl3L in Placentae from Sheep Somatic Cell Nuclear Transfer (SCNT) Conceptuses Author(s): Marta Czernik, Paola Toschi, Federica Zacchini, Domenico Iuso, Grażyna Ewa Ptak Published in: PLOS ONE, Issue 12/1, 2017, Page(s) e0169579, ISSN 1932-6203 Publisher: Public Library of Science DOI: 10.1371/journal.pone.0169579 Paternal age effects on sperm FOXK1 and KCNA7 methylation and transmission into the next generation Author(s): Stefanie Atsem, Juliane Reichenbach, Ramya Potabattula, Marcus Dittrich, Caroline Nava, Christel Depienne, Lena Böhm, Simone Rost, Thomas Hahn, Martin Schorsch, Thomas Haaf, Nady El Hajj Published in: Human Molecular Genetics, 2016, Page(s) ddw328, ISSN 0964-6906 Publisher: Oxford University Press DOI: 10.1093/hmg/ddw328 Remodeling somatic nuclei via exogenous expression of protamine 1 to create spermatid-like structures for somatic nuclear transfer Author(s): Marta Czernik, Domenico Iuso, Paola Toschi, Saadi Khochbin, Pasqualino Loi Published in: Nature Protocols, Issue 11/11, 2016, Page(s) 2170-2188, ISSN 1754-2189 Publisher: Nature Publishing Group DOI: 10.1038/nprot.2016.130 DNA methylation signatures in cord blood of ICSI children Author(s): Nady El Hajj, Larissa Haertle, Marcus Dittrich, Sarah Denk, Harald Lehnen, Thomas Hahn, Martin Schorsch, Thomas Haaf Published in: Human Reproduction, 2017, Page(s) 1-9, ISSN 0268-1161 Publisher: Oxford University Press DOI: 10.1093/humrep/dex209 Epigenetics of stress adaptations in the brain Author(s): Adrian M. Stankiewicz, Artur H. Swiergiel, Pawel Lisowski Published in: Brain Research Bulletin, Issue 03619230, 2013, Page(s) 76-92, ISSN 0361-9230 Publisher: Elsevier BV DOI: 10.1016/j.brainresbull.2013.07.003 Effects of blastomere biopsy on post-natal growth and behavior in mice Author(s): S. Sampino, F. Zacchini, A. H. Swiergiel, A. J. Modlinski, P. Loi, G. E. Ptak Published in: Human Reproduction, Issue 02681161, 2014, Page(s) 1875-1883, ISSN 0268-1161 Publisher: Oxford University Press DOI: 10.1093/humrep/deu145 Global gene expression profiling of porcine endometria on Days 12 and 16 of the estrous cycle and pregnancy Author(s): Jolanta Kiewisz, Kamil Krawczynski, Pawel Lisowski, Agnieszka Blitek, Lech Zwierzchowski, Adam J. Ziecik, Monika M. Kaczmarek Published in: Theriogenology, Issue 0093691X, 2014, Page(s) 897-909, ISSN 0093-691X Publisher: Elsevier BV DOI: 10.1016/j.theriogenology.2014.07.009 Studies on Survival of Horse Oocytes After Rapid-i Method Vitrification Author(s): Agnieszka Nowak, Joanna Kochan, Krzysztof Papis, Adam Okólski Published in: Journal of Equine Veterinary Science, Issue 07370806, 2014, Page(s) 675-679, ISSN 0737-0806 Publisher: W. B. Saunders Co., Ltd. DOI: 10.1016/j.jevs.2013.12.013 The Effect of Acute and Chronic Social Stress on the Hippocampal Transcriptome in Mice Author(s): Adrian M. Stankiewicz, Joanna Goscik, Alicja Majewska, Artur H. Swiergiel, Grzegorz R. Juszczak Published in: PLOS ONE, Issue 19326203, 2015, Page(s) e0142195, ISSN 1932-6203 Publisher: Public Library of Science DOI: 10.1371/journal.pone.0142195 PEG3 domain gene expression in maternal and foetal placenta in intrauterine growth restricted bovine foetuses Author(s): Shun Li, Hubert Pausch, Heli Venhoranta, Krzysztof Adamowicz, Magnus Andersson, Lech Zwierzchowski, Alexander Kind, Angelika Schnieke, Krzysztof Flisikowski Published in: Animal Genetics, Issue 02689146, 2016, Page(s) 106-109, ISSN 0268-9146 Publisher: Blackwell Publishing Inc. DOI: 10.1111/age.12373 Children born from frozen embryos stored for 10 years – analysis of 5 cases Author(s): Krzysztof Papis, Piotr Lewandowski, Jan Wolski, Katarzyna Kozioł Published in: Polish Gynaecology, Issue 00170011, 2013, ISSN 0017-0011 Publisher: Poskie Towarzystwo Ginekologiczne/Polish Society of Gynaecology DOI: 10.17772/gp/1669 Genomic Stability of Lyophilized Sheep Somatic Cells before and after Nuclear Transfer Author(s): Domenico Iuso, Marta Czernik, Fiorella Di Egidio, Silvestre Sampino, Federica Zacchini, Michal Bochenek, Zdzislaw Smorag, Jacek A. Modlinski, Grazyna Ptak, Pasqualino Loi Published in: PLoS ONE, Issue 19326203, 2013, Page(s) e51317, ISSN 1932-6203 Publisher: Public Library of Science DOI: 10.1371/journal.pone.0051317 Anatomy of a blastocyst: Cell behaviors driving cell fate choice and morphogenesis in the early mouse embryo Author(s): Nadine Schrode, Panagiotis Xenopoulos, Anna Piliszek, Stephen Frankenberg, Berenika Plusa, Anna-Katerina Hadjantonakis Published in: genesis, Issue 1526954X, 2013, Page(s) 219-233, ISSN 1526-954X Publisher: John Wiley & Sons Inc. DOI: 10.1002/dvg.22368 Cell fate in animal and human blastocysts and the determination of viability Author(s): Anna Piliszek, Joanna B. Grabarek, Stephen R. Frankenberg, Berenika Plusa Published in: Molecular Human Reproduction, Issue 13609947, 2016, Page(s) gaw002, ISSN 1360-9947 Publisher: Oxford University Press DOI: 10.1093/molehr/gaw002 Grand-paternal age and the development of autism-like symptoms in mice progeny Author(s): S Sampino, G R Juszczak, F Zacchini, A H Swiergiel, J A Modlinski, P Loi, G E Ptak Published in: Translational Psychiatry, Issue 21583188, 2014, Page(s) e386, ISSN 2158-3188 Publisher: Nature Publishing Group DOI: 10.1038/tp.2014.27 The T-box transcription factor Eomesodermin is essential for AVE induction in the mouse embryo Author(s): S. Nowotschin, I. Costello, A. Piliszek, G. S. Kwon, C.-a. Mao, W. H. Klein, E. J. Robertson, A.-K. Hadjantonakis Published in: Genes & Development, Issue 08909369, 2013, Page(s) 997-1002, ISSN 0890-9369 Publisher: Cold Spring Harbor Laboratory Press DOI: 10.1101/gad.215152.113 Impaired Placental Vasculogenesis Compromises the Growth of Sheep Embryos Developed In Vitro Author(s): A. Fidanza, P. Toschi, F. Zacchini, M. Czernik, C. Palmieri, P. Scapolo, J. A. Modlinski, P. Loi, G. E. Ptak Published in: Biology of Reproduction, Issue 00063363, 2014, Page(s) 21-21, ISSN 0006-3363 Publisher: Society for the Study of Reproduction DOI: 10.1095/biolreprod.113.113902 Partial hydatidiform mole diagnosis in a cat: a case report Author(s): P. Jurka, M. Sacharczuk, M. Kawka, M. Sobczak-Filipiak, M. Golicz Published in: Journal of Feline Medicine and Surgery, Issue 1098612X, 2014, Page(s) 180-182, ISSN 1098-612X Publisher: W. B. Saunders Co., Ltd. DOI: 10.1177/1098612X13496247 Developmental potential of selectively enucleated mouse zygotes reconstituted with embryonic cell, embryonic stem cell and somatic cell nuclei. Author(s): GRĘDA P., MODLIŃSKI J.A., PILISZEK A. Published in: Animal Science Papers and Reports, Issue 33, 2015, Page(s) 323-336, ISSN 0860-4037 Publisher: Polish Scientific Publishers PWN Polymorphisms of the osteopontin gene and level of its expression in the reproductive tract of sows / Polimorfizm w genie osteopontyny i poziom jej ekspresji w układzie rozrodczym loch Author(s): Agnieszka Korwin-Kossakowska, Dorota Goluch, Wojciech Kapelański, Maria Bocian, Grażyna Sender Published in: Annals of Animal Science, Issue 16423402, 2013, ISSN 1642-3402 Publisher: National Research Institute of Animal Production DOI: 10.2478/aoas-2013-0006 Autophagy and apoptosis: parent-of-origin genome-dependent mechanisms of cellular self-destruction Author(s): G. E. Ptak, P. Toschi, A. Fidanza, M. Czernik, F. Zacchini, J. A. Modlinski, P. Loi Published in: Open Biology, Issue 20462441, 2014, Page(s) 140027-140027, ISSN 2046-2441 Publisher: Royal Society Publishing DOI: 10.1098/rsob.140027 Effects of vitrification of partially denuded bovine immature oocytes. Author(s): Papis K., Shimizu M., Saha S., Izaike Y., MODLIŃSKI J.A. Published in: Animal Science Papers and Reports, Issue 31, 2013, Page(s) 5-14, ISSN 0860-4037 Publisher: Polish Scientific Publishers PWN Expression pattern of STAT5A gene during early bovine embryogenesis Author(s): Krzysztof Flisikowski, Marc Boulhaeve, Fabiola P. Lopes, Eckhard Wolf, Lech Zwierzchowski Published in: Zygote, Issue 09671994, 2015, Page(s) 307-311, ISSN 0967-1994 Publisher: Cambridge University Press DOI: 10.1017/S0967199413000427 Exogenous Expression of Human Protamine 1 (hPrm1) Remodels Fibroblast Nuclei into Spermatid-like Structures Author(s): Domenico Iuso, Marta Czernik, Paola Toschi, Antonella Fidanza, Federica Zacchini, Robert Feil, Sandrine Curtet, Thierry Buchou, Hitoshi Shiota, Saadi Khochbin, Grazyna Ewa Ptak, Pasqualino Loi Published in: Cell Reports, Issue 22111247, 2015, Page(s) 1765-1771, ISSN 2211-1247 Publisher: Cell Press DOI: 10.1016/j.celrep.2015.10.066 Embryonic diapause in humans: time to consider? Author(s): Grazyna E Ptak, Jacek A Modlinski, Pasqualino Loi Published in: Reproductive Biology and Endocrinology, Issue 14777827, 2013, Page(s) 92, ISSN 1477-7827 Publisher: BioMed Central DOI: 10.1186/1477-7827-11-92 Searching for OpenAIRE data... 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