Objective Assisted Reproduction Technologies (ART) are developing rapidly to provide response to infertility and to the cultural shift to postpone parenthood. Later childbearing and ART has been associated with an increased risk of the epigenetic disorders in offspring. Thus, in order to guarantee better and safer healthcare for EU citizens, risks and benefits of the use of various ART procedures needs to be thoughtfully tested. The project aims at overcoming the existing gaps and strengthening our capacity in Epigenetic Risk Assessment of Assisted Reproduction Technologies (ERA of ART). Long term GOAL of our project is to become the European Centre of Excellence and Innovation for Epigenetic Risk Assessment of ART. To do this, we will create link between IGAB PAS, providing high quality know-how in mouse embryology with University of Wuerzburg (leader in epigenetic assessment of ART embryos), with University of Teramo (having long-standing expertise in wide range of ART procedures in large animals) and with Uniwersytet Jagiellonski (having long-standing expertise in human genetics). This twinning project will provide technological platform and expertise for epigenetic analyses and ART in large and small animal models. The specific aims of our project based on SWOT analysis are: 1) to enhance the scientific and technical skills of our staff; 2) stimulate preparation of joint research projects; 3) produce high impact factor publications and; 4) establish the cooperation with infertility clinics. The expected impact of this project is the creation of European Reference Network for ART safety evaluation, which is within the priorities of The Third Health Programme 2014-2020 of EC as well as within thematic area: HEALTHY SOCIETY of National Smart Specializations. This will have positive impact on the research in reproductive medicine and ART sector in general and will create a unique opportunity for Polish institution to become the reference Centre for knowledge-based decision making while preparing ART legislation. Fields of science medical and health sciencesmedical biotechnologymedical and health sciencesclinical medicineobstetricsfetal medicinenatural sciencesbiological sciencesreproductive biology Programme(s) H2020-EU.4.b. - Twinning of research institutions Main Programme Topic(s) H2020-TWINN-2015 - Twinning Call for proposal H2020-TWINN-2015 See other projects for this call Funding Scheme CSA - Coordination and support action Coordinator INSTYTUT GENETYKI I BIOTECHNOLOGII ZWIERZAT POLSKIEJ AKADEMII NAUK Net EU contribution € 471 685,00 Address Jastrzebiec, ul. postepu 36a 05-552 Magdalenka Poland See on map Region Makroregion województwo mazowieckie Warszawski stołeczny Warszawski zachodni Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 471 685,00 Participants (3) Sort alphabetically Sort by Net EU contribution Expand all Collapse all JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG Germany Net EU contribution € 212 500,00 Address Sanderring 2 97070 Wuerzburg See on map Region Bayern Unterfranken Würzburg, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 212 500,00 UNIVERSITA DEGLI STUDI DI TERAMO Italy Net EU contribution € 271 500,00 Address Via renato balzarini 1 3 5 7 64100 Teramo See on map Region Sud Abruzzo Teramo Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 271 500,00 UNIWERSYTET JAGIELLONSKI Poland Net EU contribution € 221 015,00 Address Ul golebia 24 31-007 Krakow See on map Region Makroregion południowy Małopolskie Miasto Kraków Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 221 015,00