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Artificial endosymbiosis

Publicaciones

Dual Site-Selective Presentation of Functional Handles on Protein-Engineered Cowpea Chlorotic Mottle Virus-Like Particles

Autores: Daan F. M. Vervoort, Robin Heiringhoff, Suzanne B. P. E. Timmermans, Marleen H. M. E. van Stevendaal, Jan C. M. van Hest
Publicado en: Bioconjugate Chemistry, Edición 32/5, 2021, Página(s) 958-963, ISSN 1043-1802
Editor: American Chemical Society
DOI: 10.1021/acs.bioconjchem.1c00108

Therapeutic Stomatocytes with Aggregation Induced Emission for Intracellular Delivery

Autores: Jingxin Shao, Shoupeng Cao, Hanglong Wu, Loai KEA Abdelmohsen, Jan C.M. van Hest
Publicado en: PHARMACEUTICS, 2021, ISSN 1999-4923
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13111833

Amphiphilic AIEgen-polymer aggregates: Design, self-assembly and biomedical applications

Autores: Shoupeng Cao,Jingxin Shao,Loai K. E. A. Abdelmohsen,Jan C. M. van Hest
Publicado en: Aggregate, 2021, ISSN 2692-4560
Editor: John Wiley and Sons
DOI: 10.1002/agt2.128

Photoactivated Polymersome Nanomotors: Traversing Biological Barriers

Autores: Jingxin Shao, Shoupeng Cao, David S. Williams, Loai K. E. A. Abdelmohsen, Jan C. M. Hest
Publicado en: Angewandte Chemie International Edition, Edición 59/39, 2020, Página(s) 16918-16925, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202003748

Biodegradable Polymersomes with Structure Inherent Fluorescence and Targeting Capacity for Enhanced Photo-Dynamic Therapy

Autores: Shoupeng Cao,Yifeng Xia,Jingxin Shao,Beibei Guo,Yangyang Dong, Imke A. B. Pijpers, Zhiyuan Zhong,Fenghua Meng, Loai K. E. A. Abdelmohsen,David S. Williams, Jan C. M. van Hest
Publicado en: Angewandte Chemie Int Ed, 2021, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/ange.202105103

Pathway dependent shape-transformation of azide-decorated polymersomes

Autores: Hailong Che, Lafayette N. J. de Windt, Jianzhi Zhu, Imke A. B. Pijpers, Alexander F. Mason, Loai K. E. A. Abdelmohsen, Jan C. M. van Hest
Publicado en: Chemical Communications, Edición 56/14, 2020, Página(s) 2127-2130, ISSN 1359-7345
Editor: Royal Society of Chemistry
DOI: 10.1039/c9cc08944f

Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells

Autores: Wiggert J. Altenburg, N. Amy Yewdall, Daan F. M. Vervoort, Marleen H. M. E. van Stevendaal, Alexander F. Mason, Jan C. M. van Hest
Publicado en: Nature Communications, Edición 11/1, 2020, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-020-20124-0

Cucurbit-Like Polymersomes with Aggregation-Induced Emission Properties Show Enzyme-Mediated Motility

Autores: Shoupeng Cao, Hanglong Wu, Imke A. B. Pijpers, Jingxin Shao, Loai K. E. A. Abdelmohsen, David S. Williams, Jan C. M. van Hest
Publicado en: ACS Nano, 2021, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.1c07343

Engineering transient dynamics of artificial cells by stochastic distribution of enzymes

Autores: Shidong Song, Alexander F. Mason, Richard AJ Post, Marco De Corato, Rafael Mestre, N Amy Yewdall, Shoupeng Cao, Remco W van der Hofstad, Samuel Sanchez, Loai KEA Abdelmohsen, Jan C.M. van Hest
Publicado en: Nature Communications, 2021, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-021-27229-0

Artificial Organelles: Towards Adding or Restoring Intracellular Activity

Autores: Roy A. J. F. Oerlemans, Suzanne B. P. E. Timmermans, Jan C. M. Hest
Publicado en: ChemBioChem, Edición 22/12, 2021, Página(s) 2051-2078, ISSN 1439-4227
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.202000850

Engineering of Biocompatible Coacervate-Based Synthetic Cells

Autores: Marleen H. M. E. van Stevendaal, Laurynas Vasiukas, N. Amy Yewdall, Alexander F. Mason, Jan C. M. van Hest
Publicado en: ACS Applied Materials & Interfaces, Edición 13/7, 2021, Página(s) 7879-7889, ISSN 1944-8244
Editor: American Chemical Society
DOI: 10.1021/acsami.0c19052

Biomimicry of Cellular Motility and Communication Based on Synthetic Soft-Architectures

Autores: Lei Wang, Shidong Song,Jan C.M. van Hest, Loai KEA Abdelmohsen, Xin Huang, Samuel Sanchez
Publicado en: Small, 2021, ISSN 1613-6810
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.201907680

Intercellular communication between artificial cells by allosteric amplification of a molecular signal

Autores: Bastiaan C. Buddingh’, Janneke Elzinga, Jan C. M. van Hest
Publicado en: Nature Communications, Edición 11/1, 2020, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-020-15482-8

Terpolymer-stabilized complex coacervates: A robust and versatile synthetic cell platform

Autores: Alexander F. Mason,Wiggert J. Altenburg, Shidong Song, Marleen van Stevendaal, Jan C.M. van Hest
Publicado en: Methods in enzymology, 2021, ISSN 0076-6879
Editor: Academic Press
DOI: 10.1016/bs.mie.2020.06.008

Morphology Under Control: Engineering Biodegradable Stomatocytes

Autores: Imke A. B. Pijpers, Loai K. E. A. Abdelmohsen, David S. Williams, Jan C. M. van Hest
Publicado en: ACS Macro Letters, Edición 6/11, 2017, Página(s) 1217-1222, ISSN 2161-1653
Editor: American Chemical Society
DOI: 10.1021/acsmacrolett.7b00723

Feedback-Induced Temporal Control of “Breathing” Polymersomes To Create Self-Adaptive Nanoreactors

Autores: Hailong Che, Shoupeng Cao, Jan C. M. van Hest
Publicado en: Journal of the American Chemical Society, Edición 140/16, 2018, Página(s) 5356-5359, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.8b02387

Hierarchical Self-Assembly of a Copolymer-Stabilized Coacervate Protocell

Autores: Alexander F. Mason, Bastiaan C. Buddingh’, David S. Williams, Jan C. M. van Hest
Publicado en: Journal of the American Chemical Society, Edición 139/48, 2017, Página(s) 17309-17312, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.7b10846

Biodegradable Synthetic Organelles Demonstrate ROS Shielding in Human-Complex-I-Deficient Fibroblasts

Autores: Lisanne M. P. E. van Oppen, Loai K. E. A. Abdelmohsen, Sjenet E. van Emst-de Vries, Pascal L. W. Welzen, Daniela A. Wilson, Jan A. M. Smeitink, Werner J. H. Koopman, Roland Brock, Peter H. G. M. Willems, David S. Williams, Jan C.M. van Hest
Publicado en: ACS Central Science, Edición 4/7, 2018, Página(s) 917-928, ISSN 2374-7943
Editor: American Chemical Society
DOI: 10.1021/acscentsci.8b00336

Self-Assembly and Stabilization of Hybrid Cowpea Chlorotic Mottle Virus Particles under Nearly Physiological Conditions

Autores: Suzanne B. P. E. Timmermans, Daan F. M. Vervoort, Lise Schoonen, Roeland J. M. Nolte, Jan C. M. van Hest
Publicado en: Chemistry - An Asian Journal, Edición 13/22, 2018, Página(s) 3518-3525, ISSN 1861-4728
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/asia.201800842

Erythrocyte Membrane Modified Janus Polymeric Motors for Thrombus Therapy

Autores: Jingxin Shao, Mona Abdelghani, Guizhi Shen, Shoupeng Cao, David S. Williams, Jan C. M. van Hest
Publicado en: ACS Nano, Edición 12/5, 2018, Página(s) 4877-4885, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.8b01772

Physicochemical Characterization of Polymer‐stabilized Coacervate Protocells

Autores: N. Amy Yewdall, Bastiaan C. Buddingh’, Wiggert J. Altenburg, Suzanne B. P. E. Timmermans, Daan F. M. Vervoort, Loai K.E.A. Abdelmohsen, Alexander F. Mason, Jan van Hest
Publicado en: ChemBioChem, 2019, ISSN 1439-4227
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.201900195

The hallmarks of living systems: towards creating artificial cells

Autores: N. Amy Yewdall, Alexander F. Mason, Jan C. M. van Hest
Publicado en: Interface Focus, Edición 8/5, 2018, Página(s) 20180023, ISSN 2042-8898
Editor: Royal Society Publishing
DOI: 10.1098/rsfs.2018.0023

Development of Morphologically Discrete PEG–PDLLA Nanotubes for Precision Nanomedicine

Autores: Annelies C. Wauters, Imke A. B. Pijpers, Alexander F. Mason, David S. Williams, Jurjen Tel, Loai K. E. A. Abdelmohsen, Jan C.M. van Hest
Publicado en: Biomacromolecules, Edición 20/1, 2018, Página(s) 177-183, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.8b01245

Biomorphic Engineering of Multifunctional Polylactide Stomatocytes toward Therapeutic Nano-Red Blood Cells

Autores: Jingxin Shao, Imke A. B. Pijpers, Shoupeng Cao, David S. Williams, Xuehai Yan, Junbai Li, Loai K. E. A. Abdelmohsen, Jan C. M. van Hest
Publicado en: Advanced Science, Edición 6/5, 2019, Página(s) 1801678, ISSN 2198-3844
Editor: Wiley
DOI: 10.1002/advs.201801678

pH-Induced Transformation of Biodegradable Multilamellar Nanovectors for Enhanced Tumor Penetration

Autores: Shoupeng Cao, Loai K. E. A. Abdelmohsen, Jingxin Shao, Joep van den Dikkenberg, Enrico Mastrobattista, David S. Williams, Jan C. M. van Hest
Publicado en: ACS Macro Letters, Edición 7/11, 2018, Página(s) 1394-1399, ISSN 2161-1653
Editor: American Chemical Society
DOI: 10.1021/acsmacrolett.8b00807

Mimicking Cellular Compartmentalization in a Hierarchical Protocell through Spontaneous Spatial Organization

Autores: Alexander F. Mason, N. Amy Yewdall, Pascal L. W. Welzen, Jingxin Shao, Marleen van Stevendaal, Jan C. M. van Hest, David S. Williams, Loai K. E. A. Abdelmohsen
Publicado en: ACS Central Science, Edición 5/8, 2019, Página(s) 1360-1365, ISSN 2374-7943
Editor: ACS
DOI: 10.1021/acscentsci.9b00345

Adaptive Polymeric Assemblies for Applications in Biomimicry and Nanomedicine

Autores: Yigit Altay, Shoupeng Cao, Hailong Che, Loai K. E. A. Abdelmohsen, Jan C. M. van Hest
Publicado en: Biomacromolecules, Edición 20/11, 2019, Página(s) 4053-4064, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.9b01341

Adaptive Polymersome Nanoreactors

Autores: Hailong Che, Jan C. M. van Hest
Publicado en: ChemNanoMat, Edición 5/9, 2019, Página(s) 1092-1109, ISSN 2199-692X
Editor: Wiley
DOI: 10.1002/cnma.201900245

Self-Regulated and Temporal Control of a “Breathing” Microgel Mediated by Enzymatic Reaction

Autores: Hailong Che, Bastiaan C. Buddingh', Jan C. M. van Hest
Publicado en: Angewandte Chemie International Edition, Edición 56/41, 2017, Página(s) 12581-12585, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201706716

Molecular Programming of Biodegradable Nanoworms via Ionically Induced Morphology Switch toward Asymmetric Therapeutic Carriers

Autores: Shoupeng Cao, Jingxin Shao, Yifeng Xia, Hailong Che, Zhiyuan Zhong, Fenghua Meng, Jan C. M. van Hest, Loai K. E. A. Abdelmohsen, David S. Williams
Publicado en: Small, Edición 15/38, 2019, Página(s) 1901849, ISSN 1613-6810
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.201901849

Photoactivated nanomotors via aggregation induced emission for enhanced phototherapy

Autores: Shoupeng Cao, Jingxin Shao, Hanglong Wu, Shidong Song, Maria Teresa De Martino, Imke A. B. Pijpers, Heiner Friedrich, Loai K. E. A. Abdelmohsen, David S. Williams, Jan C. M. van Hest
Publicado en: Nature Communications, Edición 12/1, 2021, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-021-22279-w

ATP‐Mediated Transient Behavior of Stomatocyte Nanosystems

Autores: Hailong Che, Jianzhi Zhu, Shidong Song, Alexander F. Mason, Shoupeng Cao, Imke A. B. Pijpers, Loai K. E. A. Abdelmohsen, Jan C. M. Hest
Publicado en: Angewandte Chemie, Edición 131/37, 2019, Página(s) 13247-13252, ISSN 0044-8249
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/ange.201906331

Compartmentalized cross-linked enzymatic nano -aggregates ( c -CLE n A) for efficient in-flow biocatalysis

Autores: M. Teresa De Martino, Fabio Tonin, N. Amy Yewdall, Mona Abdelghani, David S. Williams, Ulf Hanefeld, Floris P. J. T. Rutjes, Loai K. E. A. Abdelmohsen, Jan C. M. van Hest
Publicado en: Chemical Science, Edición 11/10, 2020, Página(s) 2765-2769, ISSN 2041-6520
Editor: Royal Society of Chemistry
DOI: 10.1039/c9sc05420k

Dynamic spatial and structural organization in artificial cells regulates signal processing by protein scaffolding

Autores: Bastiaan C. Buddingh', Antoni Llopis-Lorente, Loai K. E. A. Abdelmohsen, Jan C. M. van Hest
Publicado en: Chemical Science, Edición 11/47, 2020, Página(s) 12829-12834, ISSN 2041-6520
Editor: Royal Society of Chemistry
DOI: 10.1039/d0sc03933k

Hybrid Biodegradable Nanomotors through Compartmentalized Synthesis

Autores: Imke A. B. Pijpers, Shoupeng Cao, Antoni Llopis-Lorente, Jianzhi Zhu, Shidong Song, Rick R. M. Joosten, Fenghua Meng, Heiner Friedrich, David S. Williams, Samuel Sánchez, Jan C. M. van Hest, Loai K. E. A. Abdelmohsen
Publicado en: Nano Letters, Edición 20/6, 2020, Página(s) 4472-4480, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.0c01268

Supramolecular Nanoscaffolds within Cytomimetic Protocells as Signal Localization Hubs

Autores: Eva Magdalena Estirado, Alexander F. Mason, Miguel Ángel Alemán García, Jan C. M. van Hest, Luc Brunsveld
Publicado en: Journal of the American Chemical Society, Edición 142/20, 2020, Página(s) 9106-9111, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.0c01732

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