The ER located master regulation of endosomal positioning and further movements

Información del proyecto

ERCOPE

Identificador del acuerdo de subvención: 694307

DOI

10.3030/694307

Proyecto cerrado

Fecha de la firma de la CE 1 Agosto 2016

Fecha de inicio 1 Septiembre 2016

Fecha de finalización 31 Agosto 2022

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 2 383 625,00

Aportación de la UE

€ 2 383 625,00

Coordinado por

ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (23)

The journey of Ca2+ through the cell – pulsing through the network of ER membrane contact sites

Autores: Cremer T, Neefjes J, Berlin I
Publicado en: J Cell Sci, 2020, ISSN 0021-9533
Editor: The Company of Biologists Ltd.
DOI: 10.1242/jcs.249136

HLA molecules in transplantation, autoimmunity and infection control: A comic book adventure

Autores: Reits E, Neefjes J
Publicado en: HLA, 2022, ISSN 0001-2815
Editor: Blackwell Publishing Inc.
DOI: 10.1111/tan.14626

Mobile late endosomes modulate peripheral endoplasmic reticulum network architecture

Autores: Spits M, Heesterbeek IT, Voortman LM, Akkermans JJ, Wijdeven RH, Cabukusta B, Neefjes J
Publicado en: EMBO rep, 2021, ISSN 1469-221X
Editor: Nature Publishing Group
DOI: 10.15252/embr.202050815

Maintaining soluble protein homeostasis between nuclear and cytoplasmic compartments across mitosis

Autores: van der Zanden SY, Jongsma MLM, Neefjes ACM, Berlin I, Neefjes J
Publicado en: Trends Cell Biol, 2022, ISSN 0962-8924
Editor: Elsevier BV
DOI: 10.1016/j.tcb.2022.06.002

CRISPR Activation Screening Identifies VGLL3-TEAD1-RUNX1/3 as a Transcriptional Complex for PD-L1 Expression

Autores: Wijdeven RH, Cabukusta B, Behr FM, Qiu X, Amiri D, Borras DM, Arens R, Liang Y, Neefjes J
Publicado en: J Immunol, 2022, ISSN 1471-4906
Editor: Elsevier BV
DOI: 10.4049/jimmunol.2100917

What the VAP: The Expanded VAP Family of Proteins Interacting With FFAT and FFAT-Related Motifs for Interorganellar Contact

Autores: Neefjes J, Cabukusta B
Publicado en: Contact (Thousand Oaks), 2021, ISSN 2158-2440
Editor: SAGE Publications Inc.
DOI: 10.1177/25152564211012246

The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class-I-Mediated Immune Responses

Autores: Jongsma MLM, de Waard AA, Raaben M, Zhang T, Cabukusta B, Platzer R, Blomen VA, Xagara A, Verkerk T, Bliss S, Kong X, Gerke C, Janssen L, Stickel E, Holst S, Plomp R, Mulder A, Ferrone S, Claas FHJ, Heemskerk MHM, Griffioen M, Halenius A, Overkleeft H, Huppa JB, Wuhrer M, Brummelkamp TR, Neefjes J, Spaapen RM
Publicado en: Immunity, 2021, ISSN 1074-7613
Editor: Cell Press
DOI: 10.1016/j.immuni.2020.11.003

Human VAPome Analysis MOSPD1 and MOSPD3 as Membrane Contac Site Proteins Internacting with FFAT-Related FFNT Motifs

Autores: Cabukusta B, Berlin I, van Elsland DM, Forkink I, Spits M, de Jong AWM, Akkermans JJLL, Wijdeven RHM, Janssen GMC, van Veelen PA, Neefjes J
Publicado en: Cell Rep, 2020, ISSN 2211-1247
Editor: Cell Press
DOI: 10.1016/j.celrep.2020.108475

Retrofusion of interalumenal MVB membranes parallels viral infections and coexists with exosome release

Autores: Perrin P, Janssen L, Janssen H, van den Broek B, Voortman LM, van Elsland D, Berlin I, Neefjes J
Publicado en: Curr Biol, 2021, ISSN 0960-9822
Editor: Cell Press
DOI: 10.1016/j.cub.2021.06.022

Chemical and genetic control of IFNγ-induced MHCII expression

Autores: Wijdeven RH, van Luijn MM, Wierenga-Wolf AF, Akkermans JJ, van den Elsen PJ, Hintzen RQ, Neefjes J
Publicado en: EMBO Rep., 2018, ISSN 1469-221X
Editor: Nature Publishing Group

Total Chemical Synthesis of SUMO and SUMO-Based Probes for Profiling the Activity of SUMO-Specific Proteases

Autores: Mulder MPC, Merkx R, Witting KF, Hameed DS, El Atmioui D, Lelieveld L, Liebelt F, Neefjes J, Berlin I, Vertegaal ACO, Ovaa H
Publicado en: Angew Chem Int Ed Engl., 2018, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.

Collateral damage: insights into bacterial mechanisms that predispose host cells to cancer

Autores: Gagnaire A, Nadel B, Raoult D, Neefjes J, Gorvel JP
Publicado en: Nat Rev Microbiol., 2017, ISSN 1740-1526
Editor: Nature Publishing Group

TBC1D5 controls the GTPase cycle of Rab7b

Autores: Borg Distefano M, Haugen LH, Wang Y, Perdreau-Dahl H, Kjos I, Jia D, Morth JP, Neefjes J, Bakke O, Progida C
Publicado en: J Cell Sci., 2018, ISSN 0021-9533
Editor: The Company of Biologists Ltd.

Increased colon cancer risk after severe Salmonella infection

Autores: Mughini-Gras L, Schaapveld M, Kramers J, Mooij S, Neefjes-Borst EA, Pelt WV, Neefjes J
Publicado en: PLoS One, 2018, ISSN 1932-6203
Editor: Public Library of Science

The EGFR odyssey - from activation to destruction in space and time

Autores: Bakker J, Spits M, Neefjes J, Berlin I
Publicado en: J Cell Sci., 2017, ISSN 0021-9533
Editor: The Company of Biologists Ltd.

Mechanisms of lysosomal positioning and movement

Autores: Cabukusta B, Neefjes J
Publicado en: Traffic, 2018, ISSN 1398-9219
Editor: Blackwell Publishing Inc.

Present Yourself! By MHC Class I and MHC Class II Molecules

Autores: Rock KL, Reits E, Neefjes J
Publicado en: Trends Immunol., 2016, ISSN 1471-4906
Editor: Elsevier BV

Moving and positioning the endolysosomal system

Autores: Bonifacino JS, Neefjes J
Publicado en: Curr Opin Cell Biol., 2017, ISSN 0955-0674
Editor: Elsevier BV

A flexible MHC class I multimer loading system for large-scale detection of antigen-specific T cells

Autores: Luimstra JJ, Garstka MA, Roex MCJ, Redeker A, Janssen GMC, van Veelen PA, Arens R, Falkenburg JHF, Neefjes J, Ovaa H
Publicado en: J Exp Med., 2018, ISSN 0022-1007
Editor: Rockefeller University Press

An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport

Autores: Jongsma ML, Berlin I, Wijdeven RH, Janssen L, Janssen GM, Garstka MA, Janssen H, Mensink M, van Veelen PA, Spaapen RM, Neefjes J
Publicado en: Cell., 2016, ISSN 2451-9456
Editor: Cell Press

Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway

Autores: Wijdeven RH, Janssen H, Nahidiazar L, Janssen L, Jalink K, Berlin I, Neefjes J
Publicado en: Nat Commun., 2016, ISSN 2041-1723
Editor: Nature Publishing Group

Control of host PTM by intracellular bacteria: An opportunity toward novel anti-infective agents

Autores: Stévenin V, Neefjes J
Publicado en: Cell Chem Biol, 2022, ISSN 0346-251X
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.chembiol.2022.04.004

The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway

Autores: Cremer T, Jongsma MLM, Trulsson F, Vertegaal ACO, Neefjes J, Berlin I
Publicado en: Cell Rep, 2021, ISSN 2211-1247
Editor: Cell Press
DOI: 10.1016/j.celrep.2020.108659