The ER located master regulation of endosomal positioning and further movements

Informazioni relative al progetto

ERCOPE

ID dell’accordo di sovvenzione: 694307

DOI

10.3030/694307

Progetto chiuso

Data della firma CE 1 Agosto 2016

Data di avvio 1 Settembre 2016

Data di completamento 31 Agosto 2022

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 2 383 625,00

Contributo UE

€ 2 383 625,00

Coordinato da

ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (23)

The journey of Ca2+ through the cell – pulsing through the network of ER membrane contact sites

Autori: Cremer T, Neefjes J, Berlin I
Pubblicato in: J Cell Sci, 2020, ISSN 0021-9533
Editore: The Company of Biologists Ltd.
DOI: 10.1242/jcs.249136

HLA molecules in transplantation, autoimmunity and infection control: A comic book adventure

Autori: Reits E, Neefjes J
Pubblicato in: HLA, 2022, ISSN 0001-2815
Editore: Blackwell Publishing Inc.
DOI: 10.1111/tan.14626

Mobile late endosomes modulate peripheral endoplasmic reticulum network architecture

Autori: Spits M, Heesterbeek IT, Voortman LM, Akkermans JJ, Wijdeven RH, Cabukusta B, Neefjes J
Pubblicato in: EMBO rep, 2021, ISSN 1469-221X
Editore: Nature Publishing Group
DOI: 10.15252/embr.202050815

Maintaining soluble protein homeostasis between nuclear and cytoplasmic compartments across mitosis

Autori: van der Zanden SY, Jongsma MLM, Neefjes ACM, Berlin I, Neefjes J
Pubblicato in: Trends Cell Biol, 2022, ISSN 0962-8924
Editore: Elsevier BV
DOI: 10.1016/j.tcb.2022.06.002

CRISPR Activation Screening Identifies VGLL3-TEAD1-RUNX1/3 as a Transcriptional Complex for PD-L1 Expression

Autori: Wijdeven RH, Cabukusta B, Behr FM, Qiu X, Amiri D, Borras DM, Arens R, Liang Y, Neefjes J
Pubblicato in: J Immunol, 2022, ISSN 1471-4906
Editore: Elsevier BV
DOI: 10.4049/jimmunol.2100917

What the VAP: The Expanded VAP Family of Proteins Interacting With FFAT and FFAT-Related Motifs for Interorganellar Contact

Autori: Neefjes J, Cabukusta B
Pubblicato in: Contact (Thousand Oaks), 2021, ISSN 2158-2440
Editore: SAGE Publications Inc.
DOI: 10.1177/25152564211012246

The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class-I-Mediated Immune Responses

Autori: Jongsma MLM, de Waard AA, Raaben M, Zhang T, Cabukusta B, Platzer R, Blomen VA, Xagara A, Verkerk T, Bliss S, Kong X, Gerke C, Janssen L, Stickel E, Holst S, Plomp R, Mulder A, Ferrone S, Claas FHJ, Heemskerk MHM, Griffioen M, Halenius A, Overkleeft H, Huppa JB, Wuhrer M, Brummelkamp TR, Neefjes J, Spaapen RM
Pubblicato in: Immunity, 2021, ISSN 1074-7613
Editore: Cell Press
DOI: 10.1016/j.immuni.2020.11.003

Human VAPome Analysis MOSPD1 and MOSPD3 as Membrane Contac Site Proteins Internacting with FFAT-Related FFNT Motifs

Autori: Cabukusta B, Berlin I, van Elsland DM, Forkink I, Spits M, de Jong AWM, Akkermans JJLL, Wijdeven RHM, Janssen GMC, van Veelen PA, Neefjes J
Pubblicato in: Cell Rep, 2020, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2020.108475

Retrofusion of interalumenal MVB membranes parallels viral infections and coexists with exosome release

Autori: Perrin P, Janssen L, Janssen H, van den Broek B, Voortman LM, van Elsland D, Berlin I, Neefjes J
Pubblicato in: Curr Biol, 2021, ISSN 0960-9822
Editore: Cell Press
DOI: 10.1016/j.cub.2021.06.022

Chemical and genetic control of IFNγ-induced MHCII expression

Autori: Wijdeven RH, van Luijn MM, Wierenga-Wolf AF, Akkermans JJ, van den Elsen PJ, Hintzen RQ, Neefjes J
Pubblicato in: EMBO Rep., 2018, ISSN 1469-221X
Editore: Nature Publishing Group

Total Chemical Synthesis of SUMO and SUMO-Based Probes for Profiling the Activity of SUMO-Specific Proteases

Autori: Mulder MPC, Merkx R, Witting KF, Hameed DS, El Atmioui D, Lelieveld L, Liebelt F, Neefjes J, Berlin I, Vertegaal ACO, Ovaa H
Pubblicato in: Angew Chem Int Ed Engl., 2018, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.

Collateral damage: insights into bacterial mechanisms that predispose host cells to cancer

Autori: Gagnaire A, Nadel B, Raoult D, Neefjes J, Gorvel JP
Pubblicato in: Nat Rev Microbiol., 2017, ISSN 1740-1526
Editore: Nature Publishing Group

TBC1D5 controls the GTPase cycle of Rab7b

Autori: Borg Distefano M, Haugen LH, Wang Y, Perdreau-Dahl H, Kjos I, Jia D, Morth JP, Neefjes J, Bakke O, Progida C
Pubblicato in: J Cell Sci., 2018, ISSN 0021-9533
Editore: The Company of Biologists Ltd.

Increased colon cancer risk after severe Salmonella infection

Autori: Mughini-Gras L, Schaapveld M, Kramers J, Mooij S, Neefjes-Borst EA, Pelt WV, Neefjes J
Pubblicato in: PLoS One, 2018, ISSN 1932-6203
Editore: Public Library of Science

The EGFR odyssey - from activation to destruction in space and time

Autori: Bakker J, Spits M, Neefjes J, Berlin I
Pubblicato in: J Cell Sci., 2017, ISSN 0021-9533
Editore: The Company of Biologists Ltd.

Mechanisms of lysosomal positioning and movement

Autori: Cabukusta B, Neefjes J
Pubblicato in: Traffic, 2018, ISSN 1398-9219
Editore: Blackwell Publishing Inc.

Present Yourself! By MHC Class I and MHC Class II Molecules

Autori: Rock KL, Reits E, Neefjes J
Pubblicato in: Trends Immunol., 2016, ISSN 1471-4906
Editore: Elsevier BV

Moving and positioning the endolysosomal system

Autori: Bonifacino JS, Neefjes J
Pubblicato in: Curr Opin Cell Biol., 2017, ISSN 0955-0674
Editore: Elsevier BV

A flexible MHC class I multimer loading system for large-scale detection of antigen-specific T cells

Autori: Luimstra JJ, Garstka MA, Roex MCJ, Redeker A, Janssen GMC, van Veelen PA, Arens R, Falkenburg JHF, Neefjes J, Ovaa H
Pubblicato in: J Exp Med., 2018, ISSN 0022-1007
Editore: Rockefeller University Press

An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport

Autori: Jongsma ML, Berlin I, Wijdeven RH, Janssen L, Janssen GM, Garstka MA, Janssen H, Mensink M, van Veelen PA, Spaapen RM, Neefjes J
Pubblicato in: Cell., 2016, ISSN 2451-9456
Editore: Cell Press

Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway

Autori: Wijdeven RH, Janssen H, Nahidiazar L, Janssen L, Jalink K, Berlin I, Neefjes J
Pubblicato in: Nat Commun., 2016, ISSN 2041-1723
Editore: Nature Publishing Group

Control of host PTM by intracellular bacteria: An opportunity toward novel anti-infective agents

Autori: Stévenin V, Neefjes J
Pubblicato in: Cell Chem Biol, 2022, ISSN 0346-251X
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.chembiol.2022.04.004

The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway

Autori: Cremer T, Jongsma MLM, Trulsson F, Vertegaal ACO, Neefjes J, Berlin I
Pubblicato in: Cell Rep, 2021, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2020.108659