Alternative Splicing Codes for Synaptic Specificity

Informazioni relative al progetto

SPLICECODE

ID dell’accordo di sovvenzione: 694584

DOI 10.3030/694584

Progetto chiuso

Data della firma CE 30 Settembre 2016

Data di avvio 1 Ottobre 2016

Data di completamento 30 Settembre 2021

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 2 496 460,00

Contributo UE € 2 496 460,00

Coordinato da

UNIVERSITAT BASEL
Switzerland

Pubblicazioni

Peer reviewed articles (11)

Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors

Autori: Luo L, Ambrozkiewicz MC, Benseler F, Chen C, Dumontier E, Falkner S, Furlanis E, Gomez AM, Hoshina N, Huang WH, Hutchison MA, Itoh-Maruoka Y, Lavery LA, Li W, Maruo T, Motohashi J, Pai EL, Pelkey KA, Pereira A, Philips T, Sinclair JL, Stogsdill JA, Traunmüller L, Wang J, Wortel J, You W, Abumaria N, Beier KT, Brose N, Burgess HA, Cepko CL, Cloutier JF, Eroglu C, Goebbels S, Kaeser PS, Kay JN, Lu
Pubblicato in: Neuron, Numero vol 106-1, 2020, Pagina/e 37-65, ISSN 0896-6273
Editore: Cell Press
DOI: 10.1016/j.neuron.2020.01.008

Beyond proteome diversity: alternative splicing as a regulator of neuronal transcript dynamics

Autori: Oriane Mauger, Peter Scheiffele
Pubblicato in: Current Opinion in Neurobiology, Numero 45, 2017, Pagina/e 162-168, ISSN 0959-4388
Editore: Elsevier BV
DOI: 10.1016/j.conb.2017.05.012

Targeted Intron Retention and Excision for Rapid Gene Regulation in Response to Neuronal Activity

Autori: Oriane Mauger, Frédéric Lemoine, Peter Scheiffele
Pubblicato in: Neuron, Numero 92/6, 2016, Pagina/e 1266-1278, ISSN 0896-6273
Editore: Cell Press
DOI: 10.1016/j.neuron.2016.11.032

An alternative splicing switch shapes neurexin repertoires in principal neurons versus interneurons in the mouse hippocampus

Autori: Thi-Minh Nguyen, Dietmar Schreiner, Le Xiao, Lisa Traunmüller, Caroline Bornmann, Peter Scheiffele
Pubblicato in: eLife, Numero 5, 2016, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/eLife.22757

Control of neuronal synapse specification by a highly dedicated alternative splicing program

Autori: L. Traunmuller, A. M. Gomez, T.-M. Nguyen, P. Scheiffele
Pubblicato in: Science, Numero 352/6288, 2016, Pagina/e 982-986, ISSN 0036-8075
Editore: American Association for the Advancement of Science
DOI: 10.1126/science.aaf2397

A Sam68-dependent alternative splicing program shapes postsynaptic protein complexes

Autori: Harald Witte, Dietmar Schreiner, Peter Scheiffele
Pubblicato in: European Journal of Neuroscience, 2018, ISSN 0953-816X
Editore: Blackwell Publishing Inc.
DOI: 10.1111/ejn.14332

Elfn1-induced constitutive activation of mGluR7 determines frequency-dependent recruitment of SOM interneurons

Autori: Tevye Jason Stachniak, Emily Lauren Sylwestrak, Peter Scheiffele, Benjamin J. Hall, Anirvan Ghosh
Pubblicato in: The Journal of Neuroscience, 2019, Pagina/e 2276-18, ISSN 0270-6474
Editore: Society for Neuroscience
DOI: 10.1523/jneurosci.2276-18.2019

Regulation of Neuronal Differentiation, Function, and Plasticity by Alternative Splicing

Autori: Elisabetta Furlanis, Peter Scheiffele
Pubblicato in: Annual Review of Cell and Developmental Biology, Numero 34/1, 2018, Pagina/e 451-469, ISSN 1081-0706
Editore: Annual Reviews, Inc.
DOI: 10.1146/annurev-cellbio-100617-062826

Landscape of ribosome-engaged transcript isoforms reveals extensive neuronal-cell-class-specific alternative splicing programs

Autori: Elisabetta Furlanis, Lisa Traunmüller, Geoffrey Fucile, Peter Scheiffele
Pubblicato in: Nature Neuroscience, 2019, ISSN 1097-6256
Editore: Nature Publishing Group

SAM68-specific splicing is required for proper selection of alternative 3’UTR isoforms in the nervous system

Autori: Yoko Iijima, Masami Tanaka, Satoko Suzuki, David Hauser, Masayuki Tanaka, Chisa Okada, Masatoshi Ito, Noriko Ayukawa, Yuji Sato, Masato Ohtsuka, Peter Scheiffele, Takatoshi Iijima
Pubblicato in: iScience, 2019, ISSN 2589-0042
Editore: Elsevier
DOI: 10.1016/j.isci.2019.11.028

Neurexins: molecular codes for shaping neuronal synapses

Autori: Andrea M Gomez, Lisa Traunmüller, Peter Scheiffele
Pubblicato in: Nature Reviews Neuroscience, Numero 22, 2021, Pagina/e 137–151, ISSN 1471-0048
Editore: Springer Nature
DOI: 10.1038/s41583-020-00415-7

Non-peer reviewed articles (3)

Cue-specific remodeling of the neuronal transcriptome through intron retention programs

Autori: Mazille, Scheiffele, Mauger
Pubblicato in: bioRxvs, 2021, ISSN 2692-8205
Editore: CSHL
DOI: 10.1101/2021.10.13.463312

The Yin and Yang of Arnt2 in Activity-Dependent Transcription

Autori: Zeynep Okur, Peter Scheiffele
Pubblicato in: Neuron, Numero 102/2, 2019, Pagina/e 270-272, ISSN 0896-6273
Editore: Cell Press
DOI: 10.1016/j.neuron.2019.04.006

Architects of neuronal wiring

Autori: Susanne Falkner, Peter Scheiffele
Pubblicato in: Science, Numero 364/6439, 2019, Pagina/e 437-438, ISSN 0036-8075
Editore: American Association for the Advancement of Science
DOI: 10.1126/science.aax3221