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CLONAL AND CELLULAR HETEROGENEITY OF BREAST CANCER AND ITS DYNAMIC EVOLUTION WITH TREATMENT

Publicaciones

Tumor diversity and the trade-off between universal cancer tasks

Autores: Jean Hausser, Pablo Szekely, Noam Bar, Anat Zimmer, Hila Sheftel, Carlos Caldas, Uri Alon
Publicado en: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
DOI: 10.1038/s41467-019-13195-1

Deciphering the signaling network of breast cancer improves drug sensitivity prediction

Autores: Marco Tognetti, Attila Gabor, Mi Yang, Valentina Cappelletti, Jonas Windhager, Oscar M. Rueda, Konstantina Charmpi, Elham Esmaeilishirazifard, Alejandra Bruna, Natalie de Souza, Carlos Caldas, Andreas Beyer, Paola Picotti, Julio Saez-Rodriguez, Bernd Bodenmiller
Publicado en: Cell Systems, Issue 12/5, 2021, Page(s) 401-418.e12, ISSN 2405-4712
DOI: 10.1016/j.cels.2021.04.002

Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response

Autores: Dimitra Georgopoulou, Maurizio Callari, Oscar M. Rueda, Abigail Shea, Alistair Martin, Agnese Giovannetti, Fatime Qosaj, Ali Dariush, Suet-Feung Chin, Larissa S. Carnevalli, Elena Provenzano, Wendy Greenwood, Giulia Lerda, Elham Esmaeilishirazifard, Martin O’Reilly, Violeta Serra, Dario Bressan, Gordon B. Mills, H. Raza Ali, Sabina S. Cosulich, Gregory J. Hannon, Alejandra Bruna, Carlos Caldas
Publicado en: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723
DOI: 10.1038/s41467-021-22303-z

TSHZ2 is an EGF-regulated tumor suppressor that binds to the cytokinesis regulator PRC1 and inhibits metastasis

Autores: Mary L. Uribe, Maik Dahlhoff, Rajbir N. Batra, Nishanth B. Nataraj, Yuya Haga, Diana Drago-Garcia, Ilaria Marrocco, Arunachalam Sekar, Soma Ghosh, Itay Vaknin, Sacha Lebon, Lior Kramarski, Yasuo Tsutsumi, Inpyo Choi, Oscar M. Rueda, Carlos Caldas, Yosef Yarden
Publicado en: Science Signaling, Issue 14/688, 2021, Page(s) eabe6156, ISSN 1937-9145
DOI: 10.1126/scisignal.abe6156