An induced pluripotent stem cell-based neuronal model of Spinocerebellar ataxia

Project Information

iPSCAtaxia

Grant agreement ID: 699978

DOI 10.3030/699978

Project closed

EC signature date 7 March 2016

Start date 1 July 2016

End date 23 January 2019

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 195 454,80

EU contribution € 195 454,80

Coordinated by

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom

Publications

Peer reviewed articles (4)

Recent advances in modelling of cerebellar ataxia using induced pluripotent stem cells

Author(s): Esther Becker
Published in: Journal of Neurology and Neuromedicine, Issue 2/7, 2017, Page(s) 11-15, ISSN 2572-942X
Publisher: Sciaccess Publishers
DOI: 10.29245/2572.942X/2017/7.1134

Neurodegeneration in SCA14 is associated with increased PKCγ kinase activity, mislocalization and aggregation

Author(s): Maggie M. K. Wong, Stephanie D. Hoekstra, Jane Vowles, Lauren M. Watson, Geraint Fuller, Andrea H. Németh, Sally A. Cowley, Olaf Ansorge, Kevin Talbot, Esther B. E. Becker
Published in: Acta Neuropathologica Communications, Issue 6/1, 2018, ISSN 2051-5960
Publisher: BioMed Central
DOI: 10.1186/s40478-018-0600-7

A Simplified Method for Generating Purkinje Cells from Human-Induced Pluripotent Stem Cells

Author(s): Lauren M. Watson, Maggie M. K. Wong, Jane Vowles, Sally A. Cowley, Esther B. E. Becker
Published in: The Cerebellum, Issue 17/4, 2018, Page(s) 419-427, ISSN 1473-4222
Publisher: Springer New York
DOI: 10.1007/s12311-017-0913-2

Dominant Mutations in GRM1 Cause Spinocerebellar Ataxia Type 44

Author(s): Lauren M. Watson, Elizabeth Bamber, Ricardo Parolin Schnekenberg, Jonathan Williams, Conceição Bettencourt, Jennifer Lickiss, Sandeep Jayawant, Katherine Fawcett, Samuel Clokie, Yvonne Wallis, Penny Clouston, David Sims, Henry Houlden, Esther B.E. Becker, Andrea H. Németh
Published in: The American Journal of Human Genetics, Issue 101/3, 2017, Page(s) 451-458, ISSN 0002-9297
Publisher: University of Chicago Press
DOI: 10.1016/j.ajhg.2017.08.005