Obiettivo This project aims to design and test a low-cost, highly sensitive and selective optical fibre sensor for testosterone, based on testosterone-recognising molecularly imprinted polymers (MIPs) combined with lossy mode resonance (LMR) structures.Optical fibre (OF) sensing has attracted great attention in the last years due to the benefits that it offers compared to traditional electronic sensors. Some of these benefits are small size, biocompatibility and immunity to electromagnetic fields. Among all OF sensors topologies, those based on spectral techniques are the most sensitive and robust. Specifically, OF sensors based on electromagnetic resonances - i. e., surface plasmon resonance (SPR) or LMR - have become a standard in the last years due to their high performance.The exciting potential of LMR-based sensors is combined in this proposal with bio-mimetic polymer technology in order to develop a new generation of sensors with defined chemical specificity. With this aim, the following specific objectives have been established:- To design and optimise the MIP formulations for the binding of testosterone while supporting and enhancing LMRs.- To characterise the properties of the MIPs regarding their structure, orientation and physical and chemical stability.- To study and optimise different deposition methods to coat the OF device with the selected polymer in order to obtain a testosterone sensor.- To model the OF sensor in order to predict its features and the optimum configuration.- To study the sensors’ response to different concentrations of testosterone in samples, evaluating its sensitivity, stability and selectivity.- To develop a small, light and low-cost system for the sensor in order to explore its commercial potential.The methodology and results obtained from this multidisciplinary project represents a generic strategy and will allow the future development of a range of new OF sensors for the detection of other substances of interest. Campo scientifico ingegneria e tecnologiananotecnologiananomaterialinanostrutture bidimensionaligrafeneingegneria e tecnologiaingegneria chimicatecnologie di separazionedesalinizzazioneosmosi inversaingegneria e tecnologiaingegneria dei materialirivestimenti e pellicoleingegneria e tecnologiaingegneria elettrica, ingegneria elettronica, ingegneria informaticaingegneria elettronicasensoriscienze naturaliscienze fisicheotticafibra ottica Programma(i) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Argomento(i) MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) Invito a presentare proposte H2020-MSCA-IF-2015 Vedi altri progetti per questo bando Meccanismo di finanziamento MSCA-IF-EF-ST - Standard EF Coordinatore UNIVERSITY OF EAST ANGLIA Contribution nette de l'UE € 183 454,80 Indirizzo Earlham road NR4 7TJ Norwich Regno Unito Mostra sulla mappa Regione East of England East Anglia Norwich and East Norfolk Tipo di attività Higher or Secondary Education Establishments Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Altri finanziamenti € 0,00
