Unraveling key genetic innovations behind the emergence of the root-nodule symbiosis

Información del proyecto

EvoNIN

Identificador del acuerdo de subvención: 703186

DOI

10.3030/703186

Proyecto finalizado el 31 Diciembre 2021

Fecha de la firma de la CE 31 Marzo 2016

Fecha de inicio 1 Septiembre 2017

Fecha de finalización 30 Marzo 2022

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 159 460,80

Aportación de la UE

€ 159 460,80

Coordinado por

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany

Objetivo

Today's world relies on usage of man-made inorganic nitrogen fertilizer. It is estimated, that 48% of the world's population could only be sustained through application of the nitrogen fertilizer. However, use of nitrogen fertilizer has profound multiple negative effects onto environment and human health. Therefore, development of the improved crops, which can use atmospheric nitrogen as a direct source of N and, therefore, do not rely on fertilizer has became the European and Global political priority. Atmospheric N2 is the largest reservoir of nitrogen on Earth, but it is unavailable to most of the land plants. However, a few plant species (mainly legumes) evolved an ability to form symbiosis with nitrogen-fixing bacteria and use atmospheric nitrogen as the primary source of N. The idea of transferring so-called root-nodule symbiosis to non-symbiotic plants has first appeared in the 1970es, when close to nothing was known about the molecular pathways behind nodulation. A significant international research effort over the past decades has resulted in unraveling the key genes involved in root nodule symbiosis in a number of legume model plants. Surprisingly, most of the discovered symbiotic genes were also found in non-symbiotic plants, making it difficult to elucidate key evolutionary innovations responsible for emergence of symbiosis. However, a long-needed detailed comparative study between nitrogen-fixers and non-fixers was not possible until now. The availability of completely sequenced plant genomes of species with nodal positions within and outside the nitrogen-fixing clade gives me the unique opportunity to compare the key symbiotic regulatory network in symbiotic and related non-symbiotic plants and elucidate which genes, regulatory connections or cis-regulatory elements are missing from the non-symbiotic plants. This knowledge will be ultimately exploited for the experimental transfer of nodulation to important non-symbiotic crops.

Ámbito científico (EuroSciVoc)

• ciencias naturales › ciencias biológicas › microbiología › bacteriología
• ciencias naturales › ciencias biológicas › ciencias biológicas del comportamiento › etología › interacción biológica
• ciencias naturales › ciencias biológicas › genética › genoma
• ciencias agrícolas › agricultura, silvicultura y pesca › agricultura › granos y semillas oleoaginosas › legumbres

Palabras clave

• regulatory network evolution
• gene duplication
• neofunctionalization
• transcriptor factor evolution
• root nodule symbiosis
• development of novel crops

Programa(s)

• H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions PROGRAMA PRINCIPAL
  
• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
  

Tema(s)

• MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF)
  

Régimen de financiación

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

Convocatoria de propuestas

H2020-MSCA-IF-2015

Coordinador

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN

• Aportación neta de la UEn: € 159 460,80
• Dirección: GESCHWISTER SCHOLL PLATZ 1 ; 80539 MUNCHEN ; Alemania
• Región: Bayern › Oberbayern › München, Kreisfreie Stadt
• Tipo de actividad: Higher or Secondary Education Establishments
• Coste total: € 159 460,80