Illuminating the mechanisms of mitochondrial DNA quality control and inheritance

Project Information

IlluMitoDNA

Grant agreement ID: 714739

DOI

10.3030/714739

Project closed

EC signature date 7 December 2016

Start date 1 August 2017

End date 31 July 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 851 834,00

EU contribution

€ 1 851 834,00

Coordinated by

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (8)

Cristae-dependent quality control of the mitochondrial genome

Author(s): Christopher Jakubke, Rodaria Roussou, Andreas Maiser, Christina Schug, Felix Thoma, David Bunk, David Hörl, Heinrich Leonhardt, Peter Walter, Till Klecker, Christof Osman
Published in: Science Advances, 2021, ISSN 2375-2548
Publisher: AAAS
DOI: 10.1126/sciadv.abi8886

Yme2, a putative RNA recognition motif and AAA+ domain containing protein, genetically interacts with the mitochondrial protein export machinery

Author(s): Nupur Sharma, Christof Osman
Published in: Biological Chemistry, 2022, ISSN 1437-4315
Publisher: De Gruyter
DOI: 10.1515/hsz-2021-0398

YeastMate: neural network-assisted segmentation of mating and budding events in Saccharomyces cerevisiae

Author(s): David Bunk, Julian Moriasy, Felix Thoma, Christopher Jakubke, Christof Osman, David Hörl
Published in: Bioinformatics, 2022, ISSN 1367-4803
Publisher: Oxford University Press
DOI: 10.1093/bioinformatics/btac107

An improved imaging system that corrects MS2-induced RNA destabilization

Author(s): Weihan Li, Anna Maekiniemi, Hanae Sato, Christof Osman, Robert H. Singer
Published in: Nature Methods, Issue 19, 2022, Page(s) 1558–1562, ISSN 1548-7091
Publisher: Nature Publishing Group
DOI: 10.1038/s41592-022-01658-1

Two mitochondrial HMG-box proteins, Cim1 and Abf2, antagonistically regulate mtDNA copy number in Saccharomyces cerevisiae

Author(s): Simon Schrott, Christof Osman
Published in: Nucleic Acids Research, 2023, Page(s) gkad849, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkad849

Power to the daughters – mitochondrial and mtDNA transmission during cell division

Author(s): Ina Aretz, Christopher Jakubke, Christof Osman
Published in: Biological Chemistry, Issue 0/0, 2019, ISSN 1431-6730
Publisher: Walter de Gruyter GmbH & Co. KG
DOI: 10.1515/hsz-2019-0337

Mrx6 regulates mitochondrial DNA copy number in S. cerevisiae by engaging the evolutionarily conserved Lon protease Pim1

Author(s): Aylin Göke, Simon Schrott, Arda Mizrak, Vladislav Belyy, Christof Osman, Peter Walter
Published in: Molecular Biology of the Cell, 2020, Page(s) mbc.E19-08-0470, ISSN 1059-1524
Publisher: American Society for Cell Biology
DOI: 10.1091/mbc.e19-08-0470

Regulation with cell size ensures mitochondrial DNA homeostasis during cell growth

Author(s): Anika Seel, Francesco Padovani, Moritz Mayer, Alissa Finster, Daniela Bureik, Felix Thoma, Christof Osman, Till Klecker, Kurt M. Schmoller
Published in: Nature Structural & Molecular Biology, Issue 30, 2023, Page(s) 1549–1560, ISSN 1545-9993
Publisher: Nature Publishing Group
DOI: 10.1038/s41594-023-01091-8