Illuminating the mechanisms of mitochondrial DNA quality control and inheritance

Informazioni relative al progetto

IlluMitoDNA

ID dell’accordo di sovvenzione: 714739

DOI 10.3030/714739

Progetto chiuso

Data della firma CE 7 Dicembre 2016

Data di avvio 1 Agosto 2017

Data di completamento 31 Luglio 2023

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 851 834,00

Contributo UE € 1 851 834,00

Coordinato da

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany

Pubblicazioni

Peer reviewed articles (8)

Cristae-dependent quality control of the mitochondrial genome

Autori: Christopher Jakubke, Rodaria Roussou, Andreas Maiser, Christina Schug, Felix Thoma, David Bunk, David Hörl, Heinrich Leonhardt, Peter Walter, Till Klecker, Christof Osman
Pubblicato in: Science Advances, 2021, ISSN 2375-2548
Editore: AAAS
DOI: 10.1126/sciadv.abi8886

Yme2, a putative RNA recognition motif and AAA+ domain containing protein, genetically interacts with the mitochondrial protein export machinery

Autori: Nupur Sharma, Christof Osman
Pubblicato in: Biological Chemistry, 2022, ISSN 1437-4315
Editore: De Gruyter
DOI: 10.1515/hsz-2021-0398

YeastMate: neural network-assisted segmentation of mating and budding events in Saccharomyces cerevisiae

Autori: David Bunk, Julian Moriasy, Felix Thoma, Christopher Jakubke, Christof Osman, David Hörl
Pubblicato in: Bioinformatics, 2022, ISSN 1367-4803
Editore: Oxford University Press
DOI: 10.1093/bioinformatics/btac107

An improved imaging system that corrects MS2-induced RNA destabilization

Autori: Weihan Li, Anna Maekiniemi, Hanae Sato, Christof Osman, Robert H. Singer
Pubblicato in: Nature Methods, Numero 19, 2022, Pagina/e 1558–1562, ISSN 1548-7091
Editore: Nature Publishing Group
DOI: 10.1038/s41592-022-01658-1

Two mitochondrial HMG-box proteins, Cim1 and Abf2, antagonistically regulate mtDNA copy number in Saccharomyces cerevisiae

Autori: Simon Schrott, Christof Osman
Pubblicato in: Nucleic Acids Research, 2023, Pagina/e gkad849, ISSN 0305-1048
Editore: Oxford University Press
DOI: 10.1093/nar/gkad849

Power to the daughters – mitochondrial and mtDNA transmission during cell division

Autori: Ina Aretz, Christopher Jakubke, Christof Osman
Pubblicato in: Biological Chemistry, Numero 0/0, 2019, ISSN 1431-6730
Editore: Walter de Gruyter GmbH & Co. KG
DOI: 10.1515/hsz-2019-0337

Mrx6 regulates mitochondrial DNA copy number in S. cerevisiae by engaging the evolutionarily conserved Lon protease Pim1

Autori: Aylin Göke, Simon Schrott, Arda Mizrak, Vladislav Belyy, Christof Osman, Peter Walter
Pubblicato in: Molecular Biology of the Cell, 2020, Pagina/e mbc.E19-08-0470, ISSN 1059-1524
Editore: American Society for Cell Biology
DOI: 10.1091/mbc.e19-08-0470

Regulation with cell size ensures mitochondrial DNA homeostasis during cell growth

Autori: Anika Seel, Francesco Padovani, Moritz Mayer, Alissa Finster, Daniela Bureik, Felix Thoma, Christof Osman, Till Klecker, Kurt M. Schmoller
Pubblicato in: Nature Structural & Molecular Biology, Numero 30, 2023, Pagina/e 1549–1560, ISSN 1545-9993
Editore: Nature Publishing Group
DOI: 10.1038/s41594-023-01091-8