Exploitation of Glycosylation Signatures for Precision Medicine

Deliverables

Publications

The sweet spot for biologics: recent advances in characterization of biotherapeutic glycoproteins

Author(s): O'Flaherty, R (O'Flaherty, Roisin) [1]; Trbojevic-Akmacic, I (Trbojevic-Akmacic, Irena) [2]; Greville, G (Greville, Gordon) [1]; Rudd, PM (Rudd, Pauline M.) [1]; Lauc, G (Lauc, Gordan) [2], [3]
Published in: EXPERT REVIEW OF PROTEOMICS, 2017, ISSN 1478-9450
Publisher: Future Drugs Ltd.
DOI: 10.1080/14789450.2018.1404907

Sialylation on O-linked glycans protects von Willebrand factor from macrophage galactose lectin-mediated clearance

Author(s): Soracha E. Ward, Jamie M. O’Sullivan, Alan B. Moran, Daniel I. R. Spencer, Richard A. Gardner, Jyotika Sharma, Judicael Fazavana, Marco Monopoli, Thomas A.J. McKinnon, Alain Chion, Sandra Haberichter, James S. O’Donnell
Published in: Haematologica, Issue 107, 2022, Page(s) 668-679, ISSN 0390-6078
Publisher: Ferrata Storti Foundation
DOI: 10.3324/haematol.2020.274720

Profiling the proteoforms of urinary prostate-specific antigen by capillary electrophoresis – mass spectrometry

Author(s): Alan B. Moran, Elena Domínguez-Vega, Jan Nouta, Tamas Pongracz, Theo M. de Reijke, Manfred Wuhrer, Guinevere S.M. Lageveen-Kammeijer
Published in: Journal of Proteomics, Issue 238, 2021, Page(s) 104148, ISSN 1874-3919
Publisher: Elsevier BV
DOI: 10.1016/j.jprot.2021.104148

Large-Scale Analysis of Apolipoprotein CIII Glycosylation by Ultrahigh Resolution Mass Spectrometry.

Author(s): Daniel Demus; Daniel Demus; Annemieke Naber; Viktoria Dotz; Bas C. Jansen; Bas C. Jansen; Marco R. Bladergroen; Jan Nouta; Eric J. G. Sijbrands; Mandy Van Hoek; Simone Nicolardi; Manfred Wuhrer
Published in: Frontiers in Chemistry, Vol 9 (2021), Issue 1, 2021, ISSN 2296-2646
Publisher: Frontiers Media S.A.
DOI: 10.3389/fchem.2021.678883

Immunoglobulin G N-Glycans as Potential Postgenomic Biomarkers for Hypertension in the Kazakh Population

Author(s): Qing Gao, Mamatyusupu Dolikun, Jerko Štambuk, Hao Wang, Feifei Zhao, Nizam Yiliham, Youxin Wang, Irena Trbojević-Akmačić, Jie Zhang, Honghong Fang, Yang Sun, Hongli Peng, Zhongyao Zhao, Di Liu, Jiaonan Liu, Qihuan Li, Qi Sun, Lijuan Wu, Gordan Lauc, Wei Wang, and Manshu Song
Published in: OMICS: A Journal of Integrative Biology, 2017, ISSN 1536-2310
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/omi.2017.0044

MS-Based Allotype-Specific Analysis of Polyclonal IgG-Fc N-Glycosylation

Author(s): Thomas Sénard, Andrea F. G. Gargano, David Falck, Steven W. de Taeye, Theo Rispens, Gestur Vidarsson, Manfred Wuhrer, Govert W. Somsen, Elena Domínguez-Vega
Published in: Frontiers in Immunology, Issue 11, 2020, ISSN 1664-3224
Publisher: Frontiers Media SA
DOI: 10.3389/fimmu.2020.02049

The association between subclass-specific IgG Fc N-glycosylation profiles and hypertension in the Uygur, Kazak, Kirgiz, and Tajik populations

Author(s): JN Liu, M Dolikun, J Štambuk, I Trbojević-Akmačić, J Zhang, H Wang, DQ Zheng, XY Zhang, HL Peng, ZY Zhao, D Liu, Y Sun, Q Sun, QH Li, JX Zhang, M Sun, WJ Cao, A Momčilović, G. Razdorov, LJ Wu, A Russell, YX Wang, MS Song, G Lauc & W Wang
Published in: JOURNAL OF HUMAN HYPERTENSION, 2018, ISSN 0950-9240
Publisher: Nature Publishing Group
DOI: 10.1038/s41371-018-0071-0

Baseline IgG-Fc N-glycosylation profile is associated with long-term outcome in a cohort of early inflammatory arthritis patients

Author(s): Thomas Sénard, Irini Flouri, Frano Vučković, Garyfalia Papadaki, Panagiota Goutakoli, Aggelos Banos, Maja Pučić-Baković, Marija Pezer, George Bertsias, Gordan Lauc, Prodromos Sidiropoulos
Published in: Arthritis Research & Therapy, Issue 24, 2022, ISSN 1478-6362
Publisher: Springer
DOI: 10.1186/s13075-022-02897-5

Fucosidases from the human gut symbiont Ruminococcus gnavus

Author(s): Haiyang Wu, Osmond Rebello, Emmanuelle H. Crost, C. David Owen, Samuel Walpole, Chloe Bennati-Granier, Didier Ndeh, Serena Monaco, Thomas Hicks, Anna Colvile, Paulina A. Urbanowicz, Martin A. Walsh, Jesus Angulo, Daniel I. R. Spencer, Nathalie Juge
Published in: Cellular and Molecular Life Sciences, 2020, ISSN 1420-682X
Publisher: Birkhauser Verlag
DOI: 10.1007/s00018-020-03514-x

Profiling and genetic control of the murine immunoglobulin G glycome

Author(s): Jasminka Krištić, Olga O. Zaytseva, Ramesh Ram, Quang Nguyen, Mislav Novokmet, Frano Vučković, Marija Vilaj, Irena Trbojević-Akmačić, Marija Pezer, Kathleen M. Davern, Grant Morahan & Gordan Lauc
Published in: NATURE CHEMICAL BIOLOGY, 2018, ISSN 1552-4450
Publisher: Nature Publishing Group
DOI: 10.1038/s41589-018-0034-3

Metformin and statin use associate with plasma protein N -glycosylation in people with type 2 diabetes

Author(s): Sunny S Singh, Annemieke Naber, Viktoria Dotz, Emma Schoep, Elham Memarian, Roderick C Slieker, Petra J M Elders, Gerda Vreeker, Simone Nicolardi, Manfred Wuhrer, Eric J G Sijbrands, Aloysius G Lieverse, Leen M 't Hart, Mandy van Hoek
Published in: BMJ Open Diabetes Research & Care, Issue 8/1, 2020, Page(s) e001230, ISSN 2052-4897
Publisher: BMJ Open Diabetes Research & Care
DOI: 10.1136/bmjdrc-2020-001230

Glycosylation of IgG Associates with Hypertension and Type 2 Diabetes Mellitus Comorbidity in the Chinese Muslim Ethnic Minorities and the Han Chinese

Author(s): Xiaoni Meng, Manshu Song, Marija Vilaj, Jerko Štambuk, Mamatyusupu Dolikun, Jie Zhang, Di Liu, Hao Wang, Xiaoyu Zhang, Jinxia Zhang, Weijie Cao, Ana Momčilović, Irena Trbojević-Akmačić, Xingang Li, Deqiang Zheng, Lijuan Wu, Xiuhua Guo, Youxin Wang, Gordan Lauc, and Wei Wang
Published in: JOURNAL OF PERSONALIZED MEDICINE, 2021, ISSN 2075-4426
Publisher: MDPI
DOI: 10.3390/jpm11070614

Plasma protein N-glycosylation is associated with cardiovascular disease, nephropathy, and retinopathy in type 2 diabetes

Author(s): Elham Memarian, Leen M 't Hart, Roderick C Slieker, Roosmarijn F L Lemmers, Amber A van der Heijden, Femke Rutters, Giel Nijpels, Emma Schoep, Aloysius G Lieverse, Eric J G Sijbrands, Manfred Wuhrer, Mandy van Hoek, Viktoria Dotz
Published in: BMJ OPEN DIABETES RESEARCH & CARE, 2021, ISSN 2052-4897
Publisher: BMJ PUBLISHING GROUP
DOI: 10.1136/bmjdrc-2021-002345

A novel glycosidase plate-based assay for the quantification of galactosylation and sialylation on human IgG

Author(s): Osmond D. Rebello, Richard A. Gardner, Paulina A. Urbanowicz, David N. Bolam, Lucy I. Crouch, David Falck & Daniel I. R. Spencer
Published in: Glycoconjugate Journal, 2020, ISSN 0282-0080
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10719-020-09953-9

Sialic Acid Derivatization of Fluorescently Labeled N-Glycans Allows Linkage Differentiation by Reversed-Phase Liquid Chromatography–Fluorescence Detection–Mass Spectrometry

Author(s): Alan B. Moran; Richard A. Gardner; Manfred Wuhrer; Guinevere S. M. Lageveen-Kammeijer; Daniel I. R. Spencer
Published in: Analytical Chemistry, 2022, ISSN 1086-4377
Publisher: ACS publications
DOI: 10.1021/acs.analchem.1c02610

Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci

Author(s): Justina Briliūtė, Paulina A. Urbanowicz, Ana S. Luis, Arnaud Baslé, Neil Paterson, Osmond Rebello, Jenifer Hendel, Didier A. Ndeh, Elisabeth C. Lowe, Eric C. Martens, Daniel I. R. Spencer, David N. Bolam, Lucy I. Crouch
Published in: Nature Microbiology, Issue 4/9, 2019, Page(s) 1571-1581, ISSN 2058-5276
Publisher: Nature
DOI: 10.1038/s41564-019-0466-x

Glycosylation of Immunoglobulin G Associates With Clinical Features of Inflammatory Bowel Diseases

Author(s): Mirna Šimurina, Noortje de Haan, Frano Vučković, Nicholas A Kennedy, Jerko Štambuk David Falck, Irena Trbojević-Akmačić, Florent Clerc, Genadij Razdorov, Anna Khon, Anna Latiano, Renata D'Incà, Silvio Danese, Stephan Targan, Carol Landers, Marla Dubinsky, Inflammatory Bowel Disease Biomarkers Consortium; Dermot P B McGovern, Vito Annese, Manfred Wuhrer, Gordan Lauc
Published in: GASTROENTEROLOGY, 2018, ISSN 0016-5085
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1053/j.gastro.2018.01.002

Increased central adiposity is associated with pro-inflammatory immunoglobulin G N-glycans

Author(s): Russell, Alyce C.; Kepka, Agnieszka; Trbojević-Akmačić, Irena; Ugrina, Ivo; Song, Manshu; Hui, Jennie; Hunter, Michael; Laws, Simon M.; Lauc, Gordan; Wang, Wei
Published in: Immunobiology, Issue 1, 2019, ISSN 0171-2985
Publisher: Elsevier BV
DOI: 10.1016/j.imbio.2018.10.002

N-glycome of the Lysosomal Glycocalyx is Altered in Niemann-Pick Type C Disease (NPC) Model Cells

Author(s): Marko Kosicek, Ivan Gudelj, Anita Horvatic, Tanja Jovic, Frano Vuckovic, Gordan Lauc, Silva Hecimovic
Published in: Molecular & Cellular Proteomics, Issue 17/4, 2018, Page(s) 631-642, ISSN 1535-9476
Publisher: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/mcp.ra117.000129

Site-specific glycosylation mapping of Fc gamma receptor IIIb from neutrophils of individual healthy donors

Author(s): Iwona Wojcik, Thomas Sénard, Erik de Graaf, George Janssen, Arnoud de Ru, Yassene Mohammed, Peter A. van Veelen, Gestur Vidarsson, Manfred Wuhrer, David Falck
Published in: Analytical Chemistry, 2020, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.0c02342

Serum N-Glycosylation RPLC-FD-MS Assay to Assess Colorectal Cancer Surgical Interventions

Author(s): Alan B. Moran; Georgia Elgood-Hunt; Yuri E. M. van der Burgt; Manfred Wuhrer; Wilma E. Mesker; Rob A. E. M. Tollenaar; Daniel I. R. Spencer; Guinevere S. M. Lageveen-Kammeijer
Published in: Biomolecules, Vol 13, Iss 6, p 896 (2023), 2023, ISSN 2813-3005
Publisher: MDPI
DOI: 10.3390/biom13060896

Software-Assisted Data Processing Workflow for Intact Glycoprotein Mass Spectrometry

Author(s): Alan B. Moran; Elena Domínguez-Vega; Manfred Wuhrer; Guinevere S. M. Lageveen-Kammeijer
Published in: J. Proteome REs, Issue 3, 2023, ISSN 1535-3893
Publisher: American Chemical Society
DOI: 10.1021/acs.jproteome.2c00762

A functional spleen contributes to afucosylated IgG in humans

Author(s): Iwona Wojcik; David E. Schmidt; Lisa A. de Neef; Minke A. E. Rab; Bob Meek; Okke de Weerdt; Manfred Wuhrer; C. Ellen van der Schoot; Jaap J. Zwaginga; Masja de Haas; David Falck; Gestur Vidarsson
Published in: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021), Issue 1, 2021, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-03196-w

Egg yolk sialylglycopeptide: purification, isolation and characterization of N-glycans from minor glycopeptide species

Author(s): Javier Mauricio Melo Diaz, Alan B. Moran, Simon R. Peel, Jenifer L. Hendel, Daniel I. R. Spencer
Published in: Organic & Biomolecular Chemistry, Issue 20, 2024, Page(s) 4905-4914, ISSN 1477-0520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2ob00615d

Serum sialylation changes in cancer

Author(s): Zejian Zhang, Manfred Wuhrer, Stephanie Holst
Published in: Glycoconjugate Journal, Issue 35/2, 2018, Page(s) 139-160, ISSN 0282-0080
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10719-018-9820-0

Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation

Author(s): Xia Shen, Lucija Klarić, Sodbo Sharapov, Massimo Mangino, Zheng Ning, Di Wu, Irena Trbojević-Akmačić, Maja Pučić-Baković, Igor Rudan, Ozren Polašek, Caroline Hayward, Timothy D. Spector, James F. Wilson, Gordan Lauc, Yurii S. Aulchenko
Published in: Nature Communications, Issue 8/1, 2017, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-017-00453-3

Glycosylation Profile of Immunoglobulin G Is Cross-Sectionally Associated With Cardiovascular Disease Risk Score and Subclinical Atherosclerosis in Two Independent Cohorts

Author(s): Cristina Menni, Ivan Gudelj, Erin Macdonald-Dunlop, Massimo Mangino, Jonas Zierer, Erim Bešić, Peter K. Joshi, Irena Trbojević-Akmačić, Phil J. Chowienczyk, Tim D. Spector, James F. Wilson, Gordan Lauc, Ana M. Valdes
Published in: Circulation Research, Issue 122/11, 2018, Page(s) 1555-1564, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCRESAHA.117.312174

Low galactosylation of IgG associates with higher risk for future diagnosis of rheumatoid arthritis during 10 years of follow-up

Author(s): Ivan Gudelj, Perttu P. Salo, Irena Trbojević-Akmačić, Malena Albers, Dragan Primorac, Markus Perola, Gordan Lauc
Published in: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Issue 1864/6, 2018, Page(s) 2034-2039, ISSN 0925-4439
Publisher: Elsevier BV
DOI: 10.1016/j.bbadis.2018.03.018

High throughput profiling of whole plasma N-glycans in type II diabetes mellitus patients and healthy individuals: A perspective from a Ghanaian population

Author(s): Eric Adua, Elham Memarian, Alyce Russell, Irena Trbojević-Akmačić, Ivan Gudelj, Julija Jurić, Peter Roberts, Gordan Lauc, Wei Wang
Published in: Archives of Biochemistry and Biophysics, Issue 661, 2019, Page(s) 10-21, ISSN 0003-9861
Publisher: Academic Press
DOI: 10.1016/j.abb.2018.10.015

Altered N‐glycosylation profiles as potential biomarkers and drug targets in diabetes

Author(s): Najda Rudman, Olga Gornik, Gordan Lauc
Published in: FEBS Letters, Issue 593/13, 2019, Page(s) 1598-1615, ISSN 0014-5793
Publisher: Elsevier BV
DOI: 10.1002/1873-3468.13495

Utilization of N-glycosylation profiles as risk stratification biomarkers for suboptimal health status and metabolic syndrome in a Ghanaian population

Author(s): Eric Adua, Elham Memarian, Alyce Russell, Irena Trbojević-Akmačić, Ivan Gudelj, Julija Jurić, Peter Roberts, Gordan Lauc, Wei Wang
Published in: Biomarkers in Medicine, Issue 13/15, 2019, Page(s) 1273-1287, ISSN 1752-0363
Publisher: Future Medicine Ltd.
DOI: 10.2217/bmm-2019-0005

Decreased Complexity of Serum N-glycan Structures Associates with Successful Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection

Author(s): Tanya M. Monaghan, Maja Pučić-Baković, Frano Vučković, Christine Lee, Dina Kao, Iwona Wójcik, Filip Kliček, Christos Polytarchou, Brandi Roach, Tom Louie, Peter Kim, Brandi Roach, Christos Polytarchou, Marcin Frankowski, Gordan Lauc
Published in: Gastroenterology, Issue 157/6, 2019, Page(s) 1676-1678.e3, ISSN 0016-5085
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1053/j.gastro.2019.08.034

Plasma N -Glycans as Emerging Biomarkers of Cardiometabolic Risk: A Prospective Investigation in the EPIC-Potsdam Cohort Study

Author(s): Clemens Wittenbecher, Tamara Štambuk, Olga Kuxhaus, Najda Rudman, Frano Vučković, Jerko Štambuk, Catarina Schiborn, Dario Rahelić, Stefan Dietrich, Olga Gornik, Markus Perola, Heiner Boeing, Matthias B. Schulze, Gordan Lauc
Published in: Diabetes Care, 2020, Page(s) dc191507, ISSN 0149-5992
Publisher: American Diabetes Association
DOI: 10.2337/dc19-1507

Glycomics for Type 2 Diabetes Biomarker Discovery: Promise of Immunoglobulin G Subclass-Specific Fragment Crystallizable N-glycosylation in the Uyghur Population

Author(s): Jiaonan Liu, Mamatyusupu Dolikun, Jerko Štambuk, Irena Trbojević-Akmačić, Jie Zhang, Jinxia Zhang, Hao Wang, Xiaoni Meng, Genadij Razdorov, Desmond Menon, Deqiang Zheng, Lijuan Wu, Youxin Wang, Manshu Song, Gordan Lauc, Wei Wang
Published in: OMICS: A Journal of Integrative Biology, Issue 23/12, 2019, Page(s) 640-648, ISSN 1557-8100
Publisher: Mary Ann Liebert, Inc.
DOI: 10.1089/omi.2019.0052

A Matrix-Assisted Laser Desorption/Ionization—Mass Spectrometry Assay for the Relative Quantitation of Antennary Fucosylated N-Glycans in Human Plasma

Author(s): Osmond D. Rebello, Simone Nicolardi, Guinevere S. M. Lageveen-Kammeijer, Jan Nouta, Richard A. Gardner, Wilma E. Mesker, Rob A. E. M. Tollenaar, Daniel I. R. Spencer, Manfred Wuhrer, David Falck
Published in: Frontiers in Chemistry, Issue 8, 2020, Page(s) 138, ISSN 2296-2646
Publisher: Frontiers Media SA
DOI: 10.3389/fchem.2020.00138

Decreased Immunoglobulin G Core Fucosylation, A Player in Antibody-dependent Cell-mediated Cytotoxicity, is Associated with Autoimmune Thyroid Diseases

Author(s): Tiphaine C. Martin, Mirna Šimurina, Marta Ząbczyńska, Marina Martinic Kavur, Magdalena Rydlewska, Marija Pezer, Kamila Kozłowska, Andrea Burri, Marija Vilaj, Renata Turek-Jabrocka, Milena Krnjajić-Tadijanović, Małgorzata Trofimiuk-Müldner, Ivo Ugrina, Anna Lityńska, Alicja Hubalewska-Dydejczyk, Irena Trbojevic-Akmacic, Ee Mun Lim, John P. Walsh, Ewa Pocheć, Tim D. Spector, Scott G. Wilso
Published in: Molecular & Cellular Proteomics, Issue 19/5, 2020, Page(s) 774-792, ISSN 1535-9476
Publisher: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/mcp.ra119.001860

Interlaboratory evaluation of plasma N-glycan antennary fucosylation as a clinical biomarker for HNF1A-MODY using liquid chromatography methods

Author(s): Daniel Demus; Bas C. Jansen; Richard A. Gardner; Paulina A. Urbanowicz; Haiyang Wu; Tamara Štambuk; Agata Juszczak; Edita Pape Medvidović; Nathalie Juge; Olga Gornik; Katharine R. Owen; Daniel I. R. Spencer
Published in: Glycoconjugate Journal, Issue 1, 2021, ISSN 0282-0080
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10719-021-09992-w

Glycosylation of human plasma lipoproteins reveals a high level of diversity, which directly impacts their functional properties.

Author(s): Vasily N. Sukhorukov; Ivan Gudelj; Maja Pučić-Baković; Emile Zakiev; Alexander N. Orekhov; Anatol Kontush; Anatol Kontush; Gordan Lauc
Published in: "Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, Elsevier, 2019, 1864 (5), pp.643-653. ⟨10.1016/j.bbalip.2019.01.005⟩", Issue 1, 2019, ISSN 1388-1981
Publisher: Elsevier BV
DOI: 10.1016/j.bbalip.2019.01.005

IgG N‐glycans are associated with prevalent and incident complications of type 2 diabetes

Author(s): Elham Memarian, Ralph Heijmans, Roderick C. Slieker, Adriana Sierra, Olga Gornik, Joline W. J. Beulens, Maja Hanic, Petra Elders, Julio Pascual, Eric Sijbrands, Gordan Lauc, Viktoria Dotz, Clara Barrios, Leen M. ’t Hart, Manfred Wuhrer, Mandy van Hoek
Published in: Diabetes/Metabolism Research and Reviews, Issue 39, 2023, ISSN 1520-7552
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/dmrr.3685

Serum protein N-glycosylation changes in multiple myeloma

Author(s): Zejian Zhanga, Marita Westhrin, Albert Bondt, Manfred Wuhrer, Therese Standal, Stephanie Holst
Published in: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2019, ISSN 0304-4165
Publisher: Elsevier BV
DOI: 10.1016/j.bbagen.2019.03.001

AB0090 BASELINE IgG-Fc N-GLYCOSYLATION PROFILE IS ASSOCIATED WITH LONG-TERM OUTCOME IN A COHORT OF EARLY INFLAMMATORY ARTHRITIS PATIENTS

Author(s): T. Sénard, I. Flouri, F. Vučković, G. Papadaki, P. Goutakoli, A. Banos, M. Pučić-Baković, M. Pezer, G. Bertsias, G. Lauc, P. Sidiropoulos
Published in: Annals of the Rheumatic Diseases, Issue 81, 2022, Page(s) 1176.2-1177, ISSN 0003-4967
Publisher: BMJ Publishing Group
DOI: 10.1136/annrheumdis-2022-eular.4480

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity.

Author(s): Mads Delbo Larsen; Erik L. de Graaf; Myrthe E. Sonneveld; H. Rosina Plomp; Jan Nouta; Willianne Hoepel; Hung-Jen Chen; Federica Linty; Remco Visser; Maximilian Brinkhaus; Tonci Sustic; Steven W. de Taeye; Arthur E. H. Bentlage; Suvi Toivonen; Carolien A. M. Koeleman; Susanna Sainio; Neeltje A. Kootstra; Philip J. M. Brouwer; Chiara Elisabeth Geyer; Ninotska I. L. Derksen; Gertjan Wolbink; Menno P.
Published in: Science, Issue 1, 2020, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abc8378

Why Not Use the Immunoglobulin G N-Glycans as Predictor Variables in Disease Biomarker–Phenotype Association Studies? A Multivariate Analysis

Author(s): Alyce C. Russell, Agnieszka Kepka, Irena Trbojević-Akmačić, Ivo Ugrina, Manshu Song, Jennie Hui, Michael Hunter, Simon M. Laws, Gordan Lauc, and Wei Wang
Published in: OMICS: A Journal of Integrative Biology, 2019, ISSN 1536-2310
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/omi.2019.0155

Development of an exoglycosidase plate-based assay for detecting α1-3,4 fucosylation biomarker in individuals with HNF1A-MODY

Author(s): Daniel Demus, Paulina A Urbanowicz, Richard A Gardner, Haiyang Wu, Agata Juszczak, Tamara Štambuk, Edita Pape Medvidović, Katharine R Owen, Olga Gornik, Nathalie Juge, Daniel I R Spencer
Published in: Glycobiology, Issue 32, 2022, Page(s) 230-238, ISSN 1460-2423
Publisher: Oxford Press
DOI: 10.1093/glycob/cwab107

Glyco(Proteo)mic Workflows for Cancer biomarker Discovery

Author(s): Alan Moran
Published in: 2023, ISBN 9789464696301
Publisher: Proefschriftmaken

Glycosylation analysis of Immune-related molecules

Author(s): Iwona Borosak
Published in: 2024, ISBN 9789465101064
Publisher: Ridderprint

Biomarker discovery in diabetes mellitus and lipid metabolism: multi-platform glyco(proteo)mic approaches

Author(s): Daniel Demus
Published in: 2024, ISBN 9789465101422
Publisher: Ridderprint

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