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Exploitation of Glycosylation Signatures for Precision Medicine

Deliverables

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Publications

Serum sialylation changes in cancer

Author(s): Zejian Zhang, Manfred Wuhrer, Stephanie Holst
Published in: Glycoconjugate Journal, Issue 35/2, 2018, Page(s) 139-160, ISSN 0282-0080
DOI: 10.1007/s10719-018-9820-0

Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation

Author(s): Xia Shen, Lucija Klarić, Sodbo Sharapov, Massimo Mangino, Zheng Ning, Di Wu, Irena Trbojević-Akmačić, Maja Pučić-Baković, Igor Rudan, Ozren Polašek, Caroline Hayward, Timothy D. Spector, James F. Wilson, Gordan Lauc, Yurii S. Aulchenko
Published in: Nature Communications, Issue 8/1, 2017, ISSN 2041-1723
DOI: 10.1038/s41467-017-00453-3

Low galactosylation of IgG associates with higher risk for future diagnosis of rheumatoid arthritis during 10 years of follow-up

Author(s): Ivan Gudelj, Perttu P. Salo, Irena Trbojević-Akmačić, Malena Albers, Dragan Primorac, Markus Perola, Gordan Lauc
Published in: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Issue 1864/6, 2018, Page(s) 2034-2039, ISSN 0925-4439
DOI: 10.1016/j.bbadis.2018.03.018

High throughput profiling of whole plasma N-glycans in type II diabetes mellitus patients and healthy individuals: A perspective from a Ghanaian population

Author(s): Eric Adua, Elham Memarian, Alyce Russell, Irena Trbojević-Akmačić, Ivan Gudelj, Julija Jurić, Peter Roberts, Gordan Lauc, Wei Wang
Published in: Archives of Biochemistry and Biophysics, Issue 661, 2019, Page(s) 10-21, ISSN 0003-9861
DOI: 10.1016/j.abb.2018.10.015

Altered N‐glycosylation profiles as potential biomarkers and drug targets in diabetes

Author(s): Najda Rudman, Olga Gornik, Gordan Lauc
Published in: FEBS Letters, Issue 593/13, 2019, Page(s) 1598-1615, ISSN 0014-5793
DOI: 10.1002/1873-3468.13495

Utilization of N-glycosylation profiles as risk stratification biomarkers for suboptimal health status and metabolic syndrome in a Ghanaian population

Author(s): Eric Adua, Elham Memarian, Alyce Russell, Irena Trbojević-Akmačić, Ivan Gudelj, Julija Jurić, Peter Roberts, Gordan Lauc, Wei Wang
Published in: Biomarkers in Medicine, Issue 13/15, 2019, Page(s) 1273-1287, ISSN 1752-0363
DOI: 10.2217/bmm-2019-0005

Decreased Complexity of Serum N-glycan Structures Associates with Successful Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection

Author(s): Tanya M. Monaghan, Maja Pučić-Baković, Frano Vučković, Christine Lee, Dina Kao, Iwona Wójcik, Filip Kliček, Christos Polytarchou, Brandi Roach, Tom Louie, Peter Kim, Brandi Roach, Christos Polytarchou, Marcin Frankowski, Gordan Lauc
Published in: Gastroenterology, Issue 157/6, 2019, Page(s) 1676-1678.e3, ISSN 0016-5085
DOI: 10.1053/j.gastro.2019.08.034

Plasma N -Glycans as Emerging Biomarkers of Cardiometabolic Risk: A Prospective Investigation in the EPIC-Potsdam Cohort Study

Author(s): Clemens Wittenbecher, Tamara Štambuk, Olga Kuxhaus, Najda Rudman, Frano Vučković, Jerko Štambuk, Catarina Schiborn, Dario Rahelić, Stefan Dietrich, Olga Gornik, Markus Perola, Heiner Boeing, Matthias B. Schulze, Gordan Lauc
Published in: Diabetes Care, 2020, Page(s) dc191507, ISSN 0149-5992
DOI: 10.2337/dc19-1507

Glycomics for Type 2 Diabetes Biomarker Discovery: Promise of Immunoglobulin G Subclass-Specific Fragment Crystallizable N-glycosylation in the Uyghur Population

Author(s): Jiaonan Liu, Mamatyusupu Dolikun, Jerko Štambuk, Irena Trbojević-Akmačić, Jie Zhang, Jinxia Zhang, Hao Wang, Xiaoni Meng, Genadij Razdorov, Desmond Menon, Deqiang Zheng, Lijuan Wu, Youxin Wang, Manshu Song, Gordan Lauc, Wei Wang
Published in: OMICS: A Journal of Integrative Biology, Issue 23/12, 2019, Page(s) 640-648, ISSN 1557-8100
DOI: 10.1089/omi.2019.0052

A Matrix-Assisted Laser Desorption/Ionization—Mass Spectrometry Assay for the Relative Quantitation of Antennary Fucosylated N-Glycans in Human Plasma

Author(s): Osmond D. Rebello, Simone Nicolardi, Guinevere S. M. Lageveen-Kammeijer, Jan Nouta, Richard A. Gardner, Wilma E. Mesker, Rob A. E. M. Tollenaar, Daniel I. R. Spencer, Manfred Wuhrer, David Falck
Published in: Frontiers in Chemistry, Issue 8, 2020, Page(s) 138, ISSN 2296-2646
DOI: 10.3389/fchem.2020.00138

Site-specific glycosylation mapping of Fc gamma receptor IIIb from neutrophils of health donors

Author(s): Iwona Wojcik, Thomas Sénard, Erik L de Graaf, George MC Janssen, Arnoud H de Ru, Yassene Mohammed, Peter A van Veelen, Gestur Vidarsson, Manfred Wuhrer, David Falck
Published in: bioRxiv, 2020
DOI: 10.1101/2020.04.29.068742