Deliverables Documents, reports (13) Progress report Progress Report will be delivered at M13. Joint Press Conference Joint Press Conference This deliverable will be delivered by UNIBO and KI Course on “European Public Funding Schemes for R&D and Innovation and Technology Transfer”. Course in Cancer Metabolism Course in Cancer Metabolism Lead Beneficiaries : CEUB and UNIBO Representative of Trainees Elections Course in Social Entrepreneurship and Managerial Skills Summer School in Metabolomics Project dissemination activities Project dissemination activities Deliverables due at M12-24-36-48 Course in Science Communication Dissemination activities in high schools Dissemination activities in high school Lead beneficiaries : UNIBO and FUV ESRs participation in Dynamo Camp Open Day ESRs participation in Dynamo Camp Open Day Lead beneficiaries: UNIBO and DYNAMO ACADEMY Project Website Recruitment procedure accomplished and list of ESRs appointed Publications Peer reviewed articles (23) Mitochondria Participate in Chemoresistance to Cisplatin in Human Ovarian Cancer Cells Author(s): Luca X. Zampieri, Debora Grasso, Caroline Bouzin, Davide Brusa, Rodrigue Rossignol, Pierre Sonveaux Published in: Molecular Cancer Research, Issue 18/9, 2020, Page(s) 1379-1391, ISSN 1541-7786 Publisher: American Association for Cancer Research DOI: 10.1158/1541-7786.mcr-19-1145 Role of coenzymes in cancer metabolism Author(s): Maheshwor Thapa, Guido Dallmann Published in: Seminars in Cell & Developmental Biology, Issue 98, 2020, Page(s) 44-53, ISSN 1084-9521 Publisher: Academic Press DOI: 10.1016/j.semcdb.2019.05.027 Metabolic and non-metabolic pathways that control cancer resistance to anthracyclines Author(s): Tânia Capelôa, Zohra Benyahia, Luca X. Zampieri, Marine C.N.M. Blackman, Pierre Sonveaux Published in: Seminars in Cell & Developmental Biology, Issue 98, 2020, Page(s) 181-191, ISSN 1084-9521 Publisher: Academic Press DOI: 10.1016/j.semcdb.2019.05.006 Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses Author(s): Ivana Kurelac, Luisa Iommarini, Renaud Vatrinet, Laura Benedetta Amato, Monica De Luise, Giulia Leone, Giulia Girolimetti, Nikkitha Umesh Ganesh, Victoria Louise Bridgeman, Luigi Ombrato, Marta Columbaro, Moira Ragazzi, Lara Gibellini, Manuela Sollazzo, Rene Gunther Feichtinger, Silvia Vidali, Maurizio Baldassarre, Sarah Foriel, Michele Vidone, Andrea Cossarizza, Daniela Grifoni, Barbara Kofler, I Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-019-08839-1 A Humanized Bone Niche Model Reveals Bone Tissue Preservation Upon Targeting Mitochondrial Complex I in Pseudo-Orthotopic Osteosarcoma Author(s): Ivana Kurelac, Ander Abarrategi, Moira Ragazzi, Luisa Iommarini, Nikkitha Umesh Ganesh, Thomas Snoeks, Dominique Bonnet, Anna Maria Porcelli, Ilaria Malanchi, Giuseppe Gasparre Published in: Journal of Clinical Medicine, Issue 8/12, 2019, Page(s) 2184, ISSN 2077-0383 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/jcm8122184 Pro- and antitumor effects of mitochondrial reactive oxygen species Author(s): Valéry L. Payen, Luca X. Zampieri, Paolo E. Porporato, Pierre Sonveaux Published in: Cancer and Metastasis Reviews, Issue 38/1-2, 2019, Page(s) 189-203, ISSN 0167-7659 Publisher: Kluwer Academic Publishers DOI: 10.1007/s10555-019-09789-2 In Vitro and In Vivo Characterization of MCT1 Inhibitor AZD3965 Confirms Preclinical Safety Compatible with Breast Cancer Treatment Author(s): Zohra Benyahia, Marine C. N. M. Blackman, Loïc Hamelin, Luca X. Zampieri, Tania Capeloa, Marie L. Bedin, Thibaut Vazeille, Olivier Schakman, Pierre Sonveaux Published in: Cancers, Issue 13/3, 2021, Page(s) 569, ISSN 2072-6694 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/cancers13030569 Succinate Anaplerosis Has an Onco-Driving Potential in Prostate Cancer Cells Author(s): Ana Carolina B. Sant’Anna-Silva, Juan A. Perez-Valencia, Marco Sciacovelli, Claude Lalou, Saharnaz Sarlak, Laura Tronci, Efterpi Nikitopoulou, Andras T. Meszaros, Christian Frezza, Rodrigue Rossignol, Erich Gnaiger, Helmut Klocker Published in: Cancers, Issue 13/7, 2021, Page(s) 1727, ISSN 2072-6694 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/cancers13071727 Metabolic Drivers in Hereditary Cancer Syndromes Author(s): Marco Sciacovelli, Christina Schmidt, Eamonn R. Maher, Christian Frezza Published in: Annual Review of Cancer Biology, Issue 4/1, 2020, Page(s) 77-97, ISSN 2472-3428 Publisher: Annual Rewiew of Cancer Biology DOI: 10.1146/annurev-cancerbio-030419-033612 The multifaceted contribution of α-ketoglutarate to tumor progression: An opportunity to exploit? Author(s): Houda Abla, Manuela Sollazzo, Giuseppe Gasparre, Luisa Iommarini, Anna Maria Porcelli Published in: Seminars in Cell & Developmental Biology, Issue 98, 2020, Page(s) 26-33, ISSN 1084-9521 Publisher: Academic Press DOI: 10.1016/j.semcdb.2019.05.031 Fumarate hydratase in cancer: A multifaceted tumour suppressor Author(s): Christina Schmidt, Marco Sciacovelli, Christian Frezza Published in: Seminars in Cell & Developmental Biology, Issue 98, 2020, Page(s) 15-25, ISSN 1084-9521 Publisher: Academic Press DOI: 10.1016/j.semcdb.2019.05.002 Ketogenic diet in the treatment of cancer – Where do we stand? Author(s): Daniela D. Weber, Sepideh Aminzadeh-Gohari, Julia Tulipan, Luca Catalano, René G. Feichtinger, Barbara Kofler Published in: Molecular Metabolism, Issue 33, 2020, Page(s) 102-121, ISSN 2212-8778 Publisher: Elsevier GmbH DOI: 10.1016/j.molmet.2019.06.026 The Oncojanus Paradigm of Respiratory Complex I Author(s): Giulia Leone, Houda Abla, Giuseppe Gasparre, Anna Porcelli, Luisa Iommarini Published in: Genes, Issue 9/5, 2018, Page(s) 243, ISSN 2073-4425 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/genes9050243 The multifaceted effects of metformin on tumor microenvironment Author(s): Ivana Kurelac, Nikkitha Umesh Ganesh, Maria Iorio, Anna Maria Porcelli, Giuseppe Gasparre Published in: Seminars in Cell & Developmental Biology, Issue 98, 2020, Page(s) 90-97, ISSN 1084-9521 Publisher: Academic Press DOI: 10.1016/j.semcdb.2019.05.010 Mitochondria in cancer Author(s): Debora Grasso, Luca X. Zampieri, Tânia Capelôa, Justine A. Van de Velde, Pierre Sonveaux Published in: Cell Stress, Issue 4/6, 2020, Page(s) 114-146, ISSN 2523-0204 Publisher: Shared Science Publishers OG DOI: 10.15698/cst2020.06.221 Therapeutic targeting of glutaminolysis as an essential strategy to combat cancer Author(s): José M. Matés, Floriana J. Di Paola, José A. Campos-Sandoval, Sybille Mazurek, Javier Márquez Published in: Seminars in Cell & Developmental Biology, Issue 98, 2020, Page(s) 34-43, ISSN 1084-9521 Publisher: Academic Press DOI: 10.1016/j.semcdb.2019.05.012 Mitochondrial Transfer in Cancer: A Comprehensive Review Author(s): Luca X. Zampieri, Catarina Silva-Almeida, Justin D. Rondeau, Pierre Sonveaux Published in: International Journal of Molecular Sciences, Issue 22/6, 2021, Page(s) 3245, ISSN 1422-0067 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms22063245 Targeting Mitochondria in Melanoma Author(s): Sepideh Aminzadeh-Gohari, Daniela D. Weber, Luca Catalano, René G. Feichtinger, Barbara Kofler, Roland Lang Published in: Biomolecules, Issue 10/10, 2020, Page(s) 1395, ISSN 2218-273X Publisher: MDPI AG DOI: 10.3390/biom10101395 Fitter Mitochondria Are Associated With Radioresistance in Human Head and Neck SQD9 Cancer Cells Author(s): Debora Grasso, Hyllana C. D. Medeiros, Luca X. Zampieri, Vanesa Bol, Pierre Danhier, Marike W. van Gisbergen, Caroline Bouzin, Davide Brusa, Vincent Grégoire, Hubert Smeets, Alphons P. M. Stassen, Ludwig J. Dubois, Philippe Lambin, Marie Dutreix, Pierre Sonveaux Published in: Frontiers in Pharmacology, Issue 11, 2020, Page(s) 1-16, ISSN 1663-9812 Publisher: Frontiers Media S.A. DOI: 10.3389/fphar.2020.00263 From old to new — Repurposing drugs to target mitochondrial energy metabolism in cancer Author(s): Sepideh Aminzadeh-Gohari, Daniela D. Weber, Silvia Vidali, Luca Catalano, Barbara Kofler, René G. Feichtinger Published in: Seminars in Cell & Developmental Biology, Issue 98, 2020, Page(s) 211-223, ISSN 1084-9521 Publisher: Academic Press DOI: 10.1016/j.semcdb.2019.05.025 A Shifty Target: Tumor-Initiating Cells and Their Metabolism Author(s): Bezuidenhout, Shoshan Published in: International Journal of Molecular Sciences, Issue 20/21, 2019, Page(s) 5370, ISSN 1422-0067 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms20215370 NDUFS3 depletion permits complex I maturation and reveals TMEM126A/OPA7 as an assembly factor binding the ND4-module intermediate Author(s): Luigi D’Angelo, Elisa Astro, Monica De Luise, Ivana Kurelac, Nikkitha Umesh-Ganesh, Shujing Ding, Ian M. Fearnley, Giuseppe Gasparre, Massimo Zeviani, Anna Maria Porcelli, Erika Fernandez-Vizarra, Luisa Iommarini Published in: Cell Reports, Issue 35/3, 2021, Page(s) 109002, ISSN 2211-1247 Publisher: Cell Press DOI: 10.1016/j.celrep.2021.109002 Targeted Metabolomics Identifies Plasma Biomarkers in Mice with Metabolically Heterogeneous Melanoma Xenografts Author(s): Daniela D. Weber, Maheshwor Thapa, Sepideh Aminzadeh-Gohari, Anna-Sophia Redtenbacher, Luca Catalano, René G. Feichtinger, Peter Koelblinger, Guido Dallmann, Michael Emberger, Barbara Kofler, Roland Lang Published in: Cancers, Issue 13/3, 2021, Page(s) 434, ISSN 2072-6694 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/cancers13030434 Non-peer reviewed articles (1) Ketogenic diet in cancer therapy Author(s): Daniela D. Weber, Sepideh Aminazdeh-Gohari, Barbara Kofler Published in: Aging, Issue 10/2, 2018, Page(s) 164-165, ISSN 1945-4589 Publisher: IMPACT JOURNALS LLC DOI: 10.18632/aging.101382 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
