International Network for Training on Risks of vascular Intimal Calcification And roads to Regression of cardiovascular diseasE

Risultati finali

Periodic report

Draft Periodic Report for the purpose of the meeting

INTRICARE special issue

INTRICARE special issue in Schattauer Thrombosis Haemostasis

Mid Term Report
Progress Report
Call for applicants

Call for applicants to be distributed via channels as described in Chapter 2.3. (M1)

Data Management Plan (DMP)

Data Management Plan DMP

Supervisory Board of the Network
MEC

Medical Ethical Committee protocols for human studies ESR10 ESR11

Website

INTRICARE website

Joint review papers

Pubblicazioni

Bone mineral density at different sites and 5 years mortality in end-stage renal disease patients: A cohort study

Autori: Ken Iseri, Abdul Rashid Qureshi, Lu Dai, Jonaz Ripsweden, Olof Heimbürger, Peter Barany, Ingrid Bergström, Peter Stenvinkel, Torkel B. Brismar, Bengt Lindholm
Pubblicato in: Bone, Numero 130, 2020, Pagina/e 115075, ISSN 8756-3282
Editore: Elsevier BV
DOI: 10.1016/j.bone.2019.115075

Different subclasses and isotypes of antibodies against phosphorylcholine in haemodialysis patients: association with mortality

Autori: S. K. Samal, A. R. Qureshi, M. Rahman, P. Stenvinkel, J. Frostegård
Pubblicato in: Clinical & Experimental Immunology, Numero 201/1, 2020, Pagina/e 94-104, ISSN 0009-9104
Editore: Blackwell Publishing Inc.
DOI: 10.1111/cei.13441

Magnetic resonance imaging of carotid plaques: current status and clinical perspectives

Autori: Mohamed Kassem, Alexandru Florea, Felix M. Mottaghy, Robert van Oostenbrugge, M. Eline Kooi
Pubblicato in: Annals of Translational Medicine, Numero 8/19, 2020, Pagina/e 1266-1266, ISSN 2305-5839
Editore: AME Publishing Company
DOI: 10.21037/atm-2020-cass-16

Early Vascular Ageing and Cellular Senescence in Chronic Kidney Disease

Autori: Lu Dai, Abdul Rashid Qureshi, Anna Witasp, Bengt Lindholm, Peter Stenvinkel
Pubblicato in: Computational and Structural Biotechnology Journal, Numero 17, 2019, Pagina/e 721-729, ISSN 2001-0370
Editore: Elsevier
DOI: 10.1016/j.csbj.2019.06.015

Cruciferous vegetables: rationale for exploring potential salutary effects of sulforaphane-rich foods in patients with chronic kidney disease

Autori: Ludmila F M F Cardozo, Livia A Alvarenga, Marcia Ribeiro, Lu Dai, Paul G Shiels, Peter Stenvinkel, Bengt Lindholm, Denise Mafra
Pubblicato in: Nutrition Reviews, 2020, ISSN 0029-6643
Editore: International Life Sciences Institute
DOI: 10.1093/nutrit/nuaa129

A biomimetic natural sciences approach to understanding the mechanisms of ageing in burden of lifestyle diseases

Autori: Lu Dai, Leon Schurgers, Paul G. Shiels, Peter Stenvinkel
Pubblicato in: Clinical Science, Numero 135/10, 2021, Pagina/e 1251-1272, ISSN 0143-5221
Editore: Portland Press, Ltd.
DOI: 10.1042/cs20201452

Integrative Multi-Omics Analysis in Calcific Aortic Valve Disease Reveals a Link to the Formation of Amyloid-Like Deposits

Autori: Marina A. Heuschkel, Nikolaos T. Skenteris, Joshua D. Hutcheson, Dewy D. van der Valk, Juliane Bremer, Philip Goody, Jesper Hjortnaes, Felix Jansen, Carlijn V.C. Bouten, Antoon van den Bogaerdt, Ljubica Matic, Nikolaus Marx, Claudia Goettsch
Pubblicato in: Cells, Numero 9/10, 2020, Pagina/e 2164, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells9102164

Extracellular Vesicles as Biomarkers in Cardiovascular Disease; Chances and Risks

Autori: Annemiek Dickhout, Rory R. Koenen
Pubblicato in: Frontiers in Cardiovascular Medicine, Numero 5, 2018, ISSN 2297-055X
Editore: Lausanne: Frontiers Media S.A
DOI: 10.3389/fcvm.2018.00113

Antibodies against Malondialdehyde in Haemodialysis Patients and Its Association with Clinical Outcomes: Differences between Subclasses and Isotypes

Autori: Shailesh Kumar Samal, Abdul Rashid Qureshi, Mizanur Rahman, Peter Stenvinkel, Johan Frostegård
Pubblicato in: Journal of Clinical Medicine, 2020, ISSN 2077-0383
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm9030753

Decoding myofibroblast origins in human kidney fibrosis

Autori: Christoph Kuppe, Mahmoud M. Ibrahim, Jennifer Kranz, Xiaoting Zhang, Susanne Ziegler, Javier Perales-Patón, Jitske Jansen, Katharina C. Reimer, James R. Smith, Ross Dobie, John R. Wilson-Kanamori, Maurice Halder, Yaoxian Xu, Nazanin Kabgani, Nadine Kaesler, Martin Klaus, Lukas Gernhold, Victor G. Puelles, Tobias B. Huber, Peter Boor, Sylvia Menzel, Remco M. Hoogenboezem, Eric M. J. Bindels, Joach
Pubblicato in: Nature, Numero 589/7841, 2021, Pagina/e 281-286, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-020-2941-1

Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification.

Autori: Martijn L. Chatrou; Diane Proudfoot; Guillaume J.J.M. van Eys; Brecht A. G. Willems; Leon J. Schurgers; Asim Cengiz Akbulut; Marie-Luce Bochaton-Piallat; Ljubica Perisic; Chris P. M. Reutelingsperger; Harald H.H.W. Schmidt; Barend Mees; C. Shanahan; Erik A.L. Biessen; Rick van Gorp; Malgorzata Furmanik; Ulf Hedin
Pubblicato in: Circulation Research, 2020, ISSN 0009-7330
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.119.316159

Skin autofluorescence, arterial stiffness and Framingham risk score as predictors of clinical outcome in chronic kidney disease patients: a cohort study

Autori: Hideyuki Mukai, Oskar Svedberg, Bengt Lindholm, Lu Dai, Olof Heimbürger, Peter Barany, Björn Anderstam, Peter Stenvinkel, Abdul Rashid Qureshi
Pubblicato in: Nephrology Dialysis Transplantation, Numero 34/3, 2018, Pagina/e 442-448, ISSN 0931-0509
Editore: Oxford University Press
DOI: 10.1093/ndt/gfx371

PET/MRI of atherosclerosis

Autori: Mueez Aizaz, Rik P. M. Moonen, Jochem A. J. van der Pol, Claudia Prieto, René M. Botnar, M. Eline Kooi
Pubblicato in: Cardiovascular Diagnosis and Therapy, Numero 10/4, 2020, Pagina/e 1120-1139, ISSN 2223-3652
Editore: AME Publishing Company
DOI: 10.21037/cdt.2020.02.09

Potential natural immunization against atherosclerosis in hibernating bears

Autori: Shailesh Kumar Samal, Ole Fröbert, Jonas Kindberg, Peter Stenvinkel, Johan Frostegård
Pubblicato in: Scientific Reports, Numero 11/1, 2021, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-021-91679-1

No Association between Thrombin Generation and Intra-Plaque Haemorrhage in Symptomatic Carotid Atherosclerotic Plaques: The Plaque at RISK (PARISK) Study

Autori: Geneviève Crombag, Henri Spronk, Patty Nelemans, Floris Schreuder, Martine Truijman, Anouk van Dijk, Alexandra de Rotte, Madieke Liem, Mat Daemen, Anton van der Steen, Werner Mess, Paul Nederkoorn, Jeroen Hendrikse, Aad van der Lugt, Joachim Wildberger, Hugo ten Cate, Robert van Oostenbrugge, M. Kooi
Pubblicato in: Thrombosis and Haemostasis, Numero 118/08, 2018, Pagina/e 1461-1469, ISSN 0340-6245
Editore: Schattauer
DOI: 10.1055/s-0038-1666858

Circulating proteins as predictors of cardiovascular mortality in end-stage renal disease

Autori: Tove Fall; Darren Green; Abdul Rashid Qureshi; Peter Stenvinkel; Axel C. Carlsson; Axel C. Carlsson; Peter Bárány; Tobias Feldreich; Tobias Feldreich; Tobias Feldreich; Juan Jesus Carrero; Olof Heimbürger; Jonas Ripsweden; Christoph Nowak; Philip A. Kalra; Nicolas Vuilleumier; Johan Ärnlöv
Pubblicato in: Journal of Nephrology, 2018, ISSN 1120-3625
Editore: Springer
DOI: 10.1007/s40620-018-0556-5

Resolution of Inflammation Through the Lipoxin and ALX/FPR2 Receptor Pathway Protects Against Abdominal Aortic Aneurysms

Autori: Marcelo H. Petri, Silke Thul, Teodora Andonova, Moritz Lindquist-Liljeqvist, Hong Jin, Nikolaos-Taxiarchis Skenteris, Hildur Arnardottir, Lars Maegdefessel, Kenneth Caidahl, Mauro Perretti, Joy Roy, Magnus Bäck
Pubblicato in: JACC: Basic to Translational Science, Numero 3/6, 2018, Pagina/e 719-727, ISSN 2452-302X
Editore: Elsevier
DOI: 10.1016/j.jacbts.2018.08.005

Cranberries – potential benefits in patients with chronic kidney disease

Autori: Livia de Almeida Alvarenga, Natália Alvarenga Borges, Laís de Souza Gouveia Moreira, Karla Thaís Resende Teixeira, José Carlos Carraro-Eduardo, Lu Dai, Peter Stenvinkel, Bengt Lindholm, Denise Mafra
Pubblicato in: Food & Function, Numero 10/6, 2019, Pagina/e 3103-3112, ISSN 2042-650X
Editore: Royal Society of Chemistry
DOI: 10.1039/c9fo00375d

Phenotypic features of vascular calcification in chronic kidney disease

Autori: L. Dai, M. Debowska, T. Lukaszuk, L. Bobrowski, P. Barany, M. Söderberg, D. Thiagarajan, J. Frostegård, L. Wennberg, B. Lindholm, A. R. Qureshi, J. Waniewski, P. Stenvinkel
Pubblicato in: Journal of Internal Medicine, Numero 287/4, 2020, Pagina/e 422-434, ISSN 0954-6820
Editore: Blackwell Publishing Inc.
DOI: 10.1111/joim.13012

Vitamin K2 Needs an RDI Separate from Vitamin K1

Autori: Asim Cengiz Akbulut, Angelina Pavlic, Ploingarm Petsophonsakul, Maurice Halder, Katarzyna Maresz, Rafael Kramann, Leon Schurgers
Pubblicato in: Nutrients, Numero 12/6, 2020, Pagina/e 1852, ISSN 2072-6643
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu12061852

Aortic Valve Calcium Associates with All-Cause Mortality Independent of Coronary Artery Calcium and Inflammation in Patients with End-Stage Renal Disease

Autori: Lu Dai, Oscar Plunde, Abdul Rashid Qureshi, Bengt Lindholm, Torkel B. Brismar, Leon J. Schurgers, Magnus Söderberg, Jonaz Ripsweden, Magnus Bäck, Peter Stenvinkel
Pubblicato in: Journal of Clinical Medicine, Numero 9/2, 2020, Pagina/e 607, ISSN 2077-0383
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm9020607

The Interplay of WNT and PPARγ Signaling in Vascular Calcification

Autori: Stefan Reinhold, W. Matthijs Blankesteijn, Sébastien Foulquier
Pubblicato in: Cells, Numero 9/12, 2020, Pagina/e 2658, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells9122658

Sodium [18F]Fluoride PET Can Efficiently Monitor In Vivo Atherosclerotic Plaque Calcification Progression and Treatment

Autori: Alexandru Florea, Julius P. Sigl, Agnieszka Morgenroth, Andreas Vogg, Sabri Sahnoun, Oliver H. Winz, Jan Bucerius, Leon J. Schurgers, Felix M. Mottaghy
Pubblicato in: Cells, Numero 10/2, 2021, Pagina/e 275, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells10020275

Development, establishment and validation of in vitro and ex vivo assays of vascular calcification

Autori: Joachim Jankowski; Joachim Jankowski; Michael Böhm; Setareh Orth-Alampour; Jana Holmar; Heidi Noels; Shruti Bhargava
Pubblicato in: Biochemical and Biophysical Research Communications, 2020, Pagina/e 462-470, ISSN 0006-291X
Editore: Academic Press
DOI: 10.1016/j.bbrc.2020.05.085

Serum 8-hydroxydeoxyguanosine, a marker of oxidative DNA damage, is associated with mortality independent of inflammation in chronic kidney disease

Autori: Lu Dai, Makoto Watanabe, Abdul Rashid Qureshi, Hideyuki Mukai, Anna Machowska, Olof Heimbürger, Peter Barany, Bengt Lindholm, Peter Stenvinkel
Pubblicato in: European Journal of Internal Medicine, Numero 68, 2019, Pagina/e 60-65, ISSN 0953-6205
Editore: Elsevier BV
DOI: 10.1016/j.ejim.2019.07.035

HER2-directed antibodies, affibodies and nanobodies as drug-delivery vehicles in breast cancer with a specific focus on radioimmunotherapy and radioimmunoimaging

Autori: Betül Altunay, Agnieszka Morgenroth, Mohsen Beheshti, Andreas Vogg, Nicholas C. L. Wong, Hong Hoi Ting, Hans-Jürgen Biersack, Elmar Stickeler, Felix M. Mottaghy
Pubblicato in: European Journal of Nuclear Medicine and Molecular Imaging, Numero 48/5, 2021, Pagina/e 1371-1389, ISSN 1619-7070
Editore: Springer Verlag
DOI: 10.1007/s00259-020-05094-1

Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification

Autori: Till Seime, Asim Cengiz Akbulut, Moritz Lindquist Liljeqvist, Antti Siika, Hong Jin, Greg Winski, Rick H. van Gorp, Eva Karlöf, Mariette Lengquist, Andrew J. Buckler, Malin Kronqvist, Olivia J. Waring, Jan H. N. Lindeman, Erik A. L. Biessen, Lars Maegdefessel, Anton Razuvaev, Leon J. Schurgers, Ulf Hedin, Ljubica Matic
Pubblicato in: Cells, Numero 10/6, 2021, Pagina/e 1276, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells10061276

Locking and loading the bullet against micro-calcification

Autori: Alexandru Florea, Agnieszka Morgenroth, Jan Bucerius, Leon J Schurgers, Felix M Mottaghy
Pubblicato in: European Journal of Preventive Cardiology, 2020, Pagina/e 204748732091113, ISSN 2047-4873
Editore: SAGE Publications Ltd
DOI: 10.1177/2047487320911138

Microvasculature and intraplaque hemorrhage in atherosclerotic carotid lesions: a cardiovascular magnetic resonance imaging study.

Autori: Martine T. B. Truijman; Werner H. Mess; Sylvia Heeneman; Robert J. van Oostenbrugge; Patty J. Nelemans; Floris H.B.M. Schreuder; Jan-Willem H.C. Daemen; Raf H. M. van Hoof; Raf H. M. van Hoof; Paul J. Nederkoorn; Stefan Vöö; Stefan Vöö; Mat J.A.P. Daemen; Geneviève A. J. C. Crombag; Geneviève A. J. C. Crombag; M. Eline Kooi; M. Eline Kooi; Joachim E. Wildberger; Joachim E. Wildberger; Nicky
Pubblicato in: Journal of Cardiovascular Magnetic Resonance, 2019, ISSN 1097-6647
Editore: BioMed Central
DOI: 10.1186/s12968-019-0524-9

The Bone-Vasculature Axis: Calcium Supplementation and the Role of Vitamin K.

Autori: Grzegorz B. Wasilewski; Grzegorz B. Wasilewski; Marc G. Vervloet; Leon J. Schurgers
Pubblicato in: Frontiers in Cardiovascular Medicine, 2019, ISSN 2297-055X
Editore: Lausanne: Frontiers Media S.A.
DOI: 10.3389/fcvm.2019.00006

Functional vitamin K insufficiency, vascular calcification and mortality in advanced chronic kidney disease: A cohort study

Autori: Lu Dai, Longkai Li, Helen Erlandsson, Armand M. G. Jaminon, Abdul Rashid Qureshi, Jonaz Ripsweden, Torkel B. Brismar, Anna Witasp, Olof Heimbürger, Hanne Skou Jørgensen, Peter Barany, Bengt Lindholm, Pieter Evenepoel, Leon J. Schurgers, Peter Stenvinkel
Pubblicato in: PLOS ONE, Numero 16/2, 2021, Pagina/e e0247623, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0247623

Association between fibrinogen and fibrinogen γ’ and atherosclerotic plaque morphology and composition in symptomatic carotid artery stenosis: Plaque-At-RISK study

Autori: A.C. van Dijk, S.J. Donkel, T. Zadi, M.A.H. Sonneveld, F.H.B.M. Schreuder, M.F. Chohan, P.J. Koudstaal, F.W.G. Leebeek, R. Saxena, J. Hendrikse, M.E. Kooi, A. van der Lugt, M.P.M. de Maat
Pubblicato in: Thrombosis Research, Numero 177, 2019, Pagina/e 130-135, ISSN 0049-3848
Editore: Pergamon Press
DOI: 10.1016/j.thromres.2019.02.030

Matrix Gla protein is an independent predictor of both intimal and medial vascular calcification in chronic kidney disease

Autori: Armand M. G. Jaminon, Lu Dai, Abdul Rashid Qureshi, Pieter Evenepoel, Jonaz Ripsweden, Magnus Söderberg, Anna Witasp, Hannes Olauson, Leon J. Schurgers, Peter Stenvinkel
Pubblicato in: Scientific Reports, Numero 10/1, 2020, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-020-63013-8

Initiation and Propagation of Vascular Calcification Is Regulated by a Concert of Platelet- and Smooth Muscle Cell-Derived Extracellular Vesicles

Autori: Leon J. Schurgers, Asim C. Akbulut, Dawid M. Kaczor, Maurice Halder, Rory R. Koenen, Rafael Kramann
Pubblicato in: Frontiers in Cardiovascular Medicine, Numero 5, 2018, ISSN 2297-055X
Editore: Frontiers in Cardiovascular Medicine
DOI: 10.3389/fcvm.2018.00036

Target identification for the diagnosis and intervention of vulnerable atherosclerotic plaques beyond 18F-fluorodeoxyglucose positron emission tomography imaging: promising tracers on the horizon

Autori: Jan Bucerius, Ingrid Dijkgraaf, Felix M. Mottaghy, Leon J. Schurgers
Pubblicato in: European Journal of Nuclear Medicine and Molecular Imaging, Numero 46/1, 2019, Pagina/e 251-265, ISSN 1619-7070
Editore: Springer Verlag
DOI: 10.1007/s00259-018-4176-z

Vitamin K: Double Bonds beyond Coagulation Insights into Differences between Vitamin K1 and K2 in Health and Disease

Autori: Maurice Halder, Ploingarm Petsophonsakul, Asim Akbulut, Angelina Pavlic, Frode Bohan, Eric Anderson, Katarzyna Maresz, Rafael Kramann, Leon Schurgers
Pubblicato in: International Journal of Molecular Sciences, Numero 20/4, 2019, Pagina/e 896, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20040896

Inverse J-shaped relation between coronary arterial calcium density and mortality in advanced chronic kidney disease

Autori: Hideyuki Mukai, Lu Dai, Zhimin Chen, Bengt Lindholm, Jonaz Ripsweden, Torkel B Brismar, Olof Heimbürger, Peter Barany, Abdul Rashid Qureshi, Magnus Söderberg, Magnus Bäck, Peter Stenvinkel
Pubblicato in: Nephrology Dialysis Transplantation, 2018, ISSN 0931-0509
Editore: Oxford University Press
DOI: 10.1093/ndt/gfy352

Wnt/β-Catenin Inhibitor Dickkopf 1

Autori: Stefan Reinhold, W. Matthijs Blankesteijn
Pubblicato in: Arteriosclerosis, Thrombosis, and Vascular Biology, Numero 39/2, 2019, Pagina/e 121-123, ISSN 1079-5642
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/atvbaha.118.312144

Correlation of computed tomography with carotid plaque transcriptomes associates calcification with lesion-stabilization

Autori: Eva Karlöf, Till Seime, Nuno Dias, Mariette Lengquist, Anna Witasp, Håkan Almqvist, Malin Kronqvist, Jesper R. Gådin, Jacob Odeberg, Lars Maegdefessel, Peter Stenvinkel, Ljubica Perisic Matic, Ulf Hedin
Pubblicato in: Atherosclerosis, 2019, ISSN 0021-9150
Editore: Elsevier BV
DOI: 10.1016/j.atherosclerosis.2019.05.005

Proteoglycan 4 is Increased in Human Calcified Aortic Valves and Enhances Valvular Interstitial Cell Calcification

Autori: Gonzalo Artiach, Miguel Carracedo, Till Seime, Oscar Plunde, Andres Laguna-Fernandez, Ljubica Matic, Anders Franco-Cereceda, Magnus Bäck
Pubblicato in: Cells, Numero 9/3, 2020, Pagina/e 684, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells9030684

Effects of Combined Vitamin K2 and Vitamin D3 Supplementation on Na[18F]F PET/MRI in Patients with Carotid Artery Disease: The INTRICATE Rationale and Trial Design

Autori: Alexandru Florea, M. Eline Kooi, Werner Mess, Leon J. Schurgers, Jan Bucerius, Felix M. Mottaghy
Pubblicato in: Nutrients, Numero 13/3, 2021, Pagina/e 994, ISSN 2072-6643
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu13030994

The role of receptor MAS in microglia-driven retinal vascular development

Autori: S. Foulquier, V. Caolo, G. Swennen, I. Milanova, S. Reinhold, C. Recarti, N. Alenina, M. Bader, U. M. Steckelings, T. Vanmierlo, M. J. Post, E. A. Jones, R. J. van Oostenbrugge, T. Unger
Pubblicato in: Angiogenesis, Numero 22/4, 2019, Pagina/e 481-489, ISSN 0969-6970
Editore: Kluwer Academic Publishers
DOI: 10.1007/s10456-019-09671-3

Symptomatic Carotid Plaques Demonstrate Less Leaky Plaque Microvasculature Compared With the Contralateral Side: A Dynamic Contrast‐Enhanced Magnetic Resonance Imaging Study

Autori: Crombag, G.; Hoof, R.H.M. van; Holtackers, R.J.; Schreuder, F.H.B.M.; Truijman, M.T.; Schreuder, T.; Orshoven, N.P. Van; Mess, W.H.; Hofman, Paul A.M.; Oostenbrugge, R.J. van; Wildberger, J.E.; Kooi, M.Eline
Pubblicato in: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Numero Bimonthly, 2019, ISSN 2047-9980
Editore: Wiley-Blackwell
DOI: 10.1161/jaha.118.011832

Early vascular ageing in chronic kidney disease: impact of inflammation, vitamin K, senescence and genomic damage

Autori: Lu Dai, Leon J Schurgers, Paul G Shiels, Peter Stenvinkel
Pubblicato in: Nephrology Dialysis Transplantation, Numero 35/Supplement_2, 2020, Pagina/e ii31-ii37, ISSN 0931-0509
Editore: Oxford University Press
DOI: 10.1093/ndt/gfaa006

Role of Uremic Toxins in Early Vascular Ageing and Calcification

Autori: Nikolaos C. Kyriakidis, Gabriela Cobo, Lu Dai, Bengt Lindholm, Peter Stenvinkel
Pubblicato in: Toxins, Numero 13/1, 2021, Pagina/e 26, ISSN 2072-6651
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/toxins13010026

Association between Biomarkers of Mineral and Bone Metabolism and Removal of Calcium and Phosphate in Hemodialysis

Autori: Malgorzata Debowska, Lu Dai, Alicja Wojcik-Zaluska, Jan Poleszczuk, Wojciech Zaluska, Bengt Lindholm, Jacek Waniewski
Pubblicato in: Blood Purification, Numero 49/1-2, 2020, Pagina/e 71-78, ISSN 0253-5068
Editore: S. Karger AG
DOI: 10.1159/000503623

Molecular Imaging of Angiogenesis in Oncology: Current Preclinical and Clinical Status

Autori: Alexandru Florea, Felix M. Mottaghy, Matthias Bauwens
Pubblicato in: International Journal of Molecular Sciences, Numero 22/11, 2021, Pagina/e 5544, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22115544

Lack of PCSK6 Increases Flow-Mediated Outward Arterial Remodeling in Mice

Autori: Samuel Röhl, Bianca E. Suur, Mariette Lengquist, Till Seime, Kenneth Caidahl, Ulf Hedin, Anders Arner, Ljubica Matic, Anton Razuvaev
Pubblicato in: Cells, Numero 9/4, 2020, Pagina/e 1009, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells9041009

Sevelamer Use in End-Stage Kidney Disease (ESKD) Patients Associates with Poor Vitamin K Status and High Levels of Gut-Derived Uremic Toxins: A Drug-Bug Interaction?

Autori: Abdul Rashid Qureshi; Peter Stenvinkel; Lu Dai; Henriette de Loor; Pieter Evenepoel; Leon J. Schurgers; Björn Meijers; Bert Bammens
Pubblicato in: Toxins, Vol 12, Iss 351, p 351 (2020), 2020, ISSN 2072-6651
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/toxins12060351

Serum concentration and vascular expression of adiponectin are differentially associated with the diabetic calcifying peripheral arteriopathy.

Autori: Franck Phan; Carole E. Aubert; Ljubica Perisic Matic; Christian Funck-Brentano; Agnès Hartemann; Peter Stenvinkel; M. Halbron; S. Kemel; Anna Witasp; Aurélie Carlier; Chloe Amouyal; Ziad A. Massy; Olivier Bourron; Jean-Marc Lacorte; Joe-Elie Salem; F. Lajat-Kiss; Sophie Liabeuf
Pubblicato in: Diabetology & Metabolic Syndrome, 2019, ISSN 1758-5996
Editore: BioMed Central
DOI: 10.1186/s13098-019-0429-7

The Role of Vascular Smooth Muscle Cells in Arterial Remodeling: Focus on Calcification-Related Processes.

Autori: Jaminon, Armand; Reesink, Koen; Kroon, Abraham; Schurgers, Leon
Pubblicato in: International Journal of Molecular Sciences, 2019, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20225694

Rapid Internalization and Nuclear Translocation of CCL5 and CXCL4 in Endothelial Cells

Autori: Annemiek Dickhout, Dawid M. Kaczor, Alexandra C. A. Heinzmann, Sanne L. N. Brouns, Johan W. M. Heemskerk, Marc A. M. J. van Zandvoort, Rory R. Koenen
Pubblicato in: International Journal of Molecular Sciences, Numero 22/14, 2021, Pagina/e 7332, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22147332

Bone mineral density and mortality in end-stage renal disease patients

Autori: Ken Iseri, Lu Dai, Zhimin Chen, Abdul Rashid Qureshi, Torkel B Brismar, Peter Stenvinkel, Bengt Lindholm
Pubblicato in: Clinical Kidney Journal, Numero 13/3, 2020, Pagina/e 307-321, ISSN 2048-8505
Editore: Oxford University Press
DOI: 10.1093/ckj/sfaa089

The higher mortality associated with low serum albumin is dependent on systemic inflammation in end-stage kidney disease

Autori: Filipa Caeiro Alves, Jia Sun, Abdul Rashid Qureshi, Lu Dai, Sunna Snaedal, Peter Bárány, Olof Heimbürger, Bengt Lindholm, Peter Stenvinkel
Pubblicato in: PLOS ONE, Numero 13/1, 2018, Pagina/e e0190410, ISSN 1932-6203
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DOI: 10.1016/j.jvssci.2020.01.001

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