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Single cell genomic analysis and perturbations of hematopoietic progenitors: Towards a refined model of hematopoiesis

Publications

Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq

Author(s): Diego Adhemar Jaitin, Assaf Weiner, Ido Yofe, David Lara-Astiaso, Hadas Keren-Shaul, Eyal David, Tomer Meir Salame, Amos Tanay, Alexander van Oudenaarden, Ido Amit
Published in: Cell, Issue 167/7, 2016, Page(s) 1883-1896.e15, ISSN 0092-8674
DOI: 10.1016/j.cell.2016.11.039

A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease

Author(s): Hadas Keren-Shaul, Amit Spinrad, Assaf Weiner, Orit Matcovitch-Natan, Raz Dvir-Szternfeld, Tyler K. Ulland, Eyal David, Kuti Baruch, David Lara-Astaiso, Beata Toth, Shalev Itzkovitz, Marco Colonna, Michal Schwartz, Ido Amit
Published in: Cell, Issue 169/7, 2017, Page(s) 1276-1290.e17, ISSN 0092-8674
DOI: 10.1016/j.cell.2017.05.018

Single-Cell Genomics: A Stepping Stone for Future Immunology Discoveries

Author(s): Amir Giladi, Ido Amit
Published in: Cell, Issue 172/1-2, 2018, Page(s) 14-21, ISSN 0092-8674
DOI: 10.1016/j.cell.2017.11.011

Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq

Author(s): Chiara Medaglia, Amir Giladi, Liat Stoler-Barak, Marco De Giovanni, Tomer Meir Salame, Adi Biram, Eyal David, Hanjie Li, Matteo Iannacone, Ziv Shulman, Ido Amit
Published in: Science, Issue 358/6370, 2017, Page(s) 1622-1626, ISSN 0036-8075
DOI: 10.1126/science.aao4277

Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis

Author(s): Amir Giladi, Franziska Paul, Yoni Herzog, Yaniv Lubling, Assaf Weiner, Ido Yofe, Diego Jaitin, Nina Cabezas-Wallscheid, Regine Dress, Florent Ginhoux, Andreas Trumpp, Amos Tanay, Ido Amit
Published in: Nature Cell Biology, Issue 20/7, 2018, Page(s) 836-846, ISSN 1465-7392
DOI: 10.1038/s41556-018-0121-4

Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells

Author(s): Chamutal Bornstein, Shir Nevo, Amir Giladi, Noam Kadouri, Marie Pouzolles, François Gerbe, Eyal David, Alice Machado, Anna Chuprin, Beáta Tóth, Ori Goldberg, Shalev Itzkovitz, Naomi Taylor, Philippe Jay, Valérie S. Zimmermann, Jakub Abramson, Ido Amit
Published in: Nature, Issue 559/7715, 2018, Page(s) 622-626, ISSN 0028-0836
DOI: 10.1038/s41586-018-0346-1

Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting

Author(s): Merav Cohen, Amir Giladi, Anna-Dorothea Gorki, Dikla Gelbard Solodkin, Mor Zada, Anastasiya Hladik, Andras Miklosi, Tomer-Meir Salame, Keren Bahar Halpern, Eyal David, Shalev Itzkovitz, Tibor Harkany, Sylvia Knapp, Ido Amit
Published in: Cell, Issue 175/4, 2018, Page(s) 1031-1044.e18, ISSN 0092-8674
DOI: 10.1016/j.cell.2018.09.009

Single cell dissection of plasma cell heterogeneity in symptomatic and asymptomatic myeloma

Author(s): Guy Ledergor, Assaf Weiner, Mor Zada, Shuang-Yin Wang, Yael C. Cohen, Moshe E. Gatt, Nimrod Snir, Hila Magen, Maya Koren-Michowitz, Katrin Herzog-Tzarfati, Hadas Keren-Shaul, Chamutal Bornstein, Ron Rotkopf, Ido Yofe, Eyal David, Venkata Yellapantula, Sigalit Kay, Moshe Salai, Dina Ben Yehuda, Arnon Nagler, Lev Shvidel, Avi Orr-Urtreger, Keren Bahar Halpern, Shalev Itzkovitz, Ola Landgren, Jesus S
Published in: Nature Medicine, Issue 24/12, 2018, Page(s) 1867-1876, ISSN 1078-8956
DOI: 10.1038/s41591-018-0269-2

Single-Cell Analysis of Diverse Pathogen Responses Defines a Molecular Roadmap for Generating Antigen-Specific Immunity

Author(s): Ronnie Blecher-Gonen, Pierre Bost, Kerry L. Hilligan, Eyal David, Tomer Meir Salame, Elsa Roussel, Lisa M. Connor, Johannes U. Mayer, Keren Bahar Halpern, Beáta Tóth, Shalev Itzkovitz, Benno Schwikowski, Franca Ronchese, Ido Amit
Published in: Cell Systems, Issue 8/2, 2019, Page(s) 109-121.e6, ISSN 2405-4712
DOI: 10.1016/j.cels.2019.01.001

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma

Author(s): Hanjie Li, Anne M. van der Leun, Ido Yofe, Yaniv Lubling, Dikla Gelbard-Solodkin, Alexander C.J. van Akkooi, Marlous van den Braber, Elisa A. Rozeman, John B.A.G. Haanen, Christian U. Blank, Hugo M. Horlings, Eyal David, Yael Baran, Akhiad Bercovich, Aviezer Lifshitz, Ton N. Schumacher, Amos Tanay, Ido Amit
Published in: Cell, Issue 176/4, 2019, Page(s) 775-789.e18, ISSN 0092-8674
DOI: 10.1016/j.cell.2018.11.043

Dissecting cellular crosstalk by sequencing physically interacting cells

Author(s): Amir Giladi, Merav Cohen, Chiara Medaglia, Yael Baran, Baoguo Li, Mor Zada, Pierre Bost, Ronnie Blecher-Gonen, Tomer-Meir Salame, Johannes U. Mayer, Eyal David, Franca Ronchese, Amos Tanay, Ido Amit
Published in: Nature Biotechnology, Issue 38/5, 2020, Page(s) 629-637, ISSN 1087-0156
DOI: 10.1038/s41587-020-0442-2