Deliverables
D55 Magplex Luminex assay system for detection and typing of BTV RNA Partner 1 12 16 M48
D6.1: Protocol for collection, shipment and onward processing of Culicoides eggs (Partner 1,11,13,14,16,18). (M24)
D73 Identification of cellular proteins partners involved in competencerefractory status of cells lines and therefore identification of the mechanisms underlying competence Partners 1 2 M48
D104 Report on protection and immune response of AdV CAV2 and rMVA vaccines against several serotypes in IFNAR mice Partners 1 2 8 9 15 19 M30
D127 High impact scientific publications all Partners M48
D45 Description of ecological factors driving population structure and of natural barriers to vector dispersion Partner 3 6 7 12 M48
Determination of levels of protection afforded by statins that have been deemed as most efficient in cell cultures using IFNAR mouse model Partner 2 M48
D75 Improved epidemiological models integrating vector competence data Partners 6 7 10 12 M48
D107 Report on protection in cattle by vaccination with a cocktail of DISA vaccines Partners 9 M48
D5.1: Serotype specific qRT-PCR for novel BTV serotypes (Partner 1, 2, 4, 5, 12, 16). (M18)
D53 Validation of the RNA microarrays Partner 1 4 5 P16 M27
D54 Diagnostic ELISA which has been evaluated Partner 1 5 16 M30
D3.4: Established friction surfaces and connectivity matrices (Partner 1, 3, 6, 7, 10, 12). (M24)
D72 Identification of protein domains involved in restricting infection of Culicoides cells Partners 1 2 16 M48
D46 A model for windborne introduction of flying insects into Europe to estimate the risk under specific climatic conditions Partner 3 6 7 12 M48
D85 Determine possibility frequency of natural reassortment between conventional and novel BTVs Partners 1 2 5 M48
D91 Characterisation of the IFN response of ruminant endothelial cells to BTV8 and BTV26 in the presence or absence of Culicoides saliva Partner 10 and 16 M48
D115 Determination of effect of statinsinhibitory molecules on vaccination regimes Partner 2 8 M48
D3.3: Refined spatial epizone maps (Partner 1, 3, 6, 7, 10, 12). (M18)
D4.1: List of required environmental and landscape factors needed (Partner 3, 6, 7) (with WP3). (M3)
D5.2: Array based system for typing BTV (Partner 1, 4, 5). (M27)
D35 Phylogeographic analysis linking BTV diffusion to epizones and vector populations Partner 1 3 6 7 10 12 M48
D106 Report on protection and immune response of AdV CAV2 rMVA and Ppastoris vaccines against several serotypes in sheep Partners 1 2 8 15 19 M48
D105 Report on early protection against one serotype in cattle by monoserotype DISA vaccination Partners 9 M24
D114 Development of potential antiviralcontrol strategies based on identification of viral proteins involved in permissiverefractory status Partner 2 8 M48
D82 Reassortant viruses between conventional eg BTV1 or BTV4 and novelatypical strains eg to explore the genetic basis for horizontal transmission Partners 1 2 4 5 M18
D81 An assessment of the the pathogenesis and horizontal transmission characteristics of BTV8 BTV26 and other novel BTV strains in goats and sheep Partners 2 4 5 M18
D92 Virus purification and sequencing modelling of VP2 cleavage sites of 10 BTV strains Partners 16 10 and 1 M48
D3.1: A list of spatial data requirements from WP1, (Partners 1, 3, 4, 10). (M3)
D116 Determination of histopathological changes in mice andor sheep treated with selected statin molecules and infected with BTV Partner 2 M48
D83 A mouse model for horizontal transmission of atypical BTV strains between mammalian hosts Partners 2 M24
D74 Standardisation of procedures for the infection of adult Culicoides vectors and vectorderived cell lines to generate statistically robust data for vector competence Partners 1 2 16 M24
D112 Identification of virusprotein targets for novel antiBTV strategies Partner 2 8 M24
D86 Identification of BTV protein domains influencing horizontal transmission in a mammalian host Partners 1 2 5 M48
D95 Attachment uptake and replication characteristics for selected BTV strains in different ruminant target cells vascular endothelial cells monocytes Partner 16 and 10 M48
D84 Identification of genome segments of the novelatypical BTV strainsserotypes that support horizontal transmission in a mammalian host Partners 1 2 4 5 M24
D93 Generation by reverse genetics and characterisation of cleavage resistant BTV strains Partners 10 16 and 1 M48
D76 Information advice for policy makers concerning the biological characteristics of novel viral strains Partners 1 2 4 5 6 9 10 12 16 M1 to M48
D96 Identification and characterisation of ruminant ISGs that block BTV replication Partner 10 M48
D111 Identification of inhibitory doses of statin molecules on selected BTV strains in cell culture Partner 2 M24
D71 Identification of individual BTV genes involved in restricting infection of Culicoides cells Partners 1 2 16 M48
D94 Infectivity assays in Culicoides KC cells and ruminant endothelial cells for selected BTV strains Partner 16 and 10 M48
D6.2: Protocol for successful generation of primary cell cultures from different Culicoides spp. (Partner 1). (M27)
D125 Adaptation and maintenance of spatial data website to include PALEBlu data all Partners M12
D3.2: Updated website with environmental and anthropogenic data archive and dissemination capabilities (Partner 1, 3, 6, 7, 10, 12). (M12)
Task 124 Establish and maintain project websites with regular updates over the project lifetime with all partners contributing new material with review of the site at every consortium meeting all Partners M1 to M36
D3.6: Archive of standardised and processed spatial data for use by WP1, WP3, & WP4 (Partner 1, 3, 6, 7, 10, 12). (M24)
D4.3: Culicoides host maps as determined by available data (Partners 3, 6, 7). (M30)
D4.2: Spatial data base of vector distributions (Partner 3, 4, 6, 7, 12). (M12)
Searching for OpenAIRE data...
Publications
Author(s): Emmanuel Bréard, Axel Gorlier, Cyril Viarouge, Fabien Donnet, Corinne Sailleau, Claudia Schulz, Bernd Hoffmann, Loic Comtet, Martin Beer, Stéphan Zientara, Damien Vitour
Published in: Transboundary and Emerging Diseases, 66/1, 2018, Page(s) 537-545, ISSN 1865-1674
Publisher: Blackwell-Wiss.-Verl
DOI: 10.1111/tbed.13060
Author(s): S Zientara 1, C Beck 1, S Lecollinet 1
Published in: Bulletin de l'Académie nationale de médecine, 2020, ISSN 0001-4079
Publisher: Elsevier BV
DOI: 10.1016/j.banm.2020.09.041
Author(s): Maude Jacquot, Pavuluri P Rao, Sarita Yadav, Kyriaki Nomikou, Sushila Maan, Y Krishna Jyothi, Narasimha Reddy, Kalyani Putty, Divakar Hemadri, Karam P Singh, Narender Singh Maan, Nagendra R Hegde, Peter Mertens, Roman Biek
Published in: Virus Evolution, 5/2, 2019, ISSN 2057-1577
Publisher: Oxford University Press
DOI: 10.1093/ve/vez027
Author(s): Moh A. Alkhamis, Cecilia Aguilar-Vega, Nicholas M. Fountain-Jones, Kai Lin, Andres M. Perez & José M. Sánchez-Vizcaíno
Published in: Scientific Reports, 20452322, 2020, Page(s) 10:21677, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-78673-9
Author(s): Houssam Attoui 1, Baptiste Monsion 1, Bernard Klonjkowski 1, Stéphan Zientara 1, Peter P C Mertens 2, Fauziah Mohd Jaafar 1
Published in: Viruses, 2021, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13112208
Author(s): Cappai S, Rolesu S, Loi F, Liciardi M, Leone A, Marcacci M, Teodori L, Mangone I, Sghaier S, Portanti O, Savini G, Lorusso A.
Published in: Transboundary and Emerging Diseases, 2019 May;66(3):1426-1431., 2019, Page(s) 1426-1431., ISSN 1865-1682
Publisher: Wiley
DOI: 10.1111/tbed.13156.
Author(s): Sahar Ahmed, Mohamed Abd El-Fatah Mahmoud, Cyril Viarouge, Corinne Sailleau, Stephan Zientara, Emmanuel Breard
Published in: Infection, Genetics and Evolution, 73, 2019, Page(s) 221-226, ISSN 1567-1348
Publisher: Elsevier BV
DOI: 10.1016/j.meegid.2019.04.033
Author(s): Cecilia Aguilar-Vega, Jaime Bosch, Eduardo Fernández-Carrión, Javier Lucientes, José Manuel Sánchez-Vizcaíno
Published in: Viruses, 12/10, 2020, Page(s) 1158, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v12101158
Author(s): Camille Jahel, Maxime Lenormand, Ismaila Seck, Andrea Apolloni, Ibra Toure, Coumba Faye, Baba Sall, Mbargou Lo, Cecile Squarzoni Diaw, Renaud Lancelot, Caroline Coste
Published in: Scientific Reports, 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-65132-8
Author(s): Cindy Kundlacz, Grégory Caignard, Corinne Sailleau, Cyril Viarouge, Lydie Postic, Damien Vitour, Stéphan Zientara, Emmanuel Breard
Published in: Viruses, 11/7, 2019, Page(s) 672, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v11070672
Author(s): Alejandro Marín-Lopez, Eva Calvo-Pinilla, Sandra Moreno, Sergio Utrilla-Trigo, Aitor Nogales, Alejandro Brun, Erol Fikrig, Javier Ortego
Published in: Viruses, 11/1, 2019, Page(s) 35, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v11010035
Author(s): Lisa M. Stevens, Katy Moffat, Lyndsay Cooke, Kyriaki Nomikou, Peter P. C. Mertens, Terry Jackson, Karin E. Darpel
Published in: Journal of General Virology, 100/4, 2019, Page(s) 568-582, ISSN 0022-1317
Publisher: Society for General Microbiology
DOI: 10.1099/jgv.0.001240
Author(s): David J. Pascall, Kyriaki Nomikou, Emmanuel Bréard, Stephan Zientara, Ana da Silva Filipe, Bernd Hoffmann, Maude Jacquot, Joshua B. Singer, Kris De Clercq, Anette Bøtner, Corinne Sailleau, Cyril Viarouge, Carrie Batten, Giantonella Puggioni, Ciriaco Ligios, Giovanni Savini, Piet A. van Rijn, Peter P. C. Mertens, Roman Biek, Massimo Palmarini
Published in: PLOS Biology, 18/4, 2020, Page(s) e3000673, ISSN 1545-7885
Publisher: Plos
DOI: 10.1371/journal.pbio.3000673
Author(s): Moh A. Alkhamis,Nicholas M. Fountain-Jones,Cecilia Aguilar-Vega,José M. Sánchez-Vizcaíno
Published in: Ecological Applications, 19395582, 2021, Page(s) 31(7):e02407. 10.1002/eap.2407, ISSN 1939-5582
Publisher: Ecological Society of America
DOI: 10.1002/eap.2407
Author(s): Flannery J, Sanz-Bernardo B, Ashby M, Brown H, Carpenter S, Cooke L, Corla A, Frost L, Gubbins S, Hicks H, Qureshi M, Rajko-Nenow P, Sanders C, Tully M, Bréard E, Sailleau C, Zientara S, Darpel K, Batten C.
Published in: Transboundary and Emerging Diseases, 2019, ISSN 1865-1682
Publisher: Wiley
DOI: 10.1111/tbed.13131.
Author(s): Pascall DJ, Nomikou K, Bréard E, Zientara S, Filipe ADS, Hoffmann B, Jacquot M, Singer JB, De Clercq K, Bøtner A, Sailleau C, Viarouge C, Batten C, Puggioni G, Ligios C, Savini G, van Rijn PA, Mertens PPC, Biek R, Palmarini M.
Published in: PLoS Biology, 2020, ISSN 1545-7885
Publisher: Public Library of Science
DOI: 10.1371/journal.pbio.3000673
Author(s): Castillo-Olivares, J.,
Published in: Equine Vet Journal, 2021, ISSN 2042-3306
Publisher: Wiley BEVA
DOI: 10.1111/evj.13353
Author(s): Lesley Bell-Sakyi, Fauziah Mohd Jaafar, Baptiste Monsion, Lisa Luu, Eric Denison, Simon Carpenter, Houssam Attoui, Peter P. C. Mertens
Published in: Microorganisms, 8/6, 2020, Page(s) 825, ISSN 2076-2607
Publisher: MDPI.AG
DOI: 10.3390/microorganisms8060825
Author(s): Utrilla-Trigo S, Jiménez-Cabello L, Calvo-Pinilla E, Marín-López A, Lorenzo G, Sánchez-Cordón P, Moreno S, Benavides J, Gilbert S, Nogales A, Ortego J.
Published in: J Virol., 2022, ISSN 1098-5514
Publisher: American Society for Microbiology
DOI: 10.1128/jvi.01614-21
Author(s): Alejandro Marín-López, Eva Calvo-Pinilla, Diego Barriales, Gema Lorenzo, Alejandro Brun, Juan Anguita, Javier Ortego
Published in: Journal of Virology, 92/16, 2018, ISSN 0022-538X
Publisher: American Society for Microbiology
DOI: 10.1128/jvi.00938-18
Author(s): Natalia Golender, Velizar Bumbarov, Avi Eldar, Alessio Lorusso, Gabriel Kenigswald, Joseph Seffi Varsano, Dan David, Shani Schainin, Ilan Dagoni, Iosef Gur, Alon Kaplan, Anna Gorohov, Ori Koren, Eldad Oron, Yevgeny Khinich, Ily Sclamovich, Abraham Meir, Giovanni Savini
Published in: Frontiers in Veterinary Science, 7, 2020, ISSN 2297-1769
Publisher: Frontiers Media S.A.
DOI: 10.3389/fvets.2020.00112
Author(s): Piet A. van Rijn
Published in: Frontiers in Veterinary Science, 6, 2019, Page(s) 407-422, ISSN 2297-1769
Publisher: Frontiers Media S.A.
DOI: 10.3389/fvets.2019.00407
Author(s): Christina Ries 1, Martin Beer 1, Bernd Hoffmann 2
Published in: Vaccine, 2019, ISSN 0264-410X
Publisher: Elsevier BV
DOI: 10.1016/j.vaccine.2019.03.082.
Author(s): Natalia Golender 1, Avi Eldar 2, Marcelo Ehrlich 3, Yevgeny Khinich 2, Gabriel Kenigswald 4, Joseph Seffi Varsano 5, Shachar Ertracht 6, Itzik Abramovitz 4, Itay Assis 4, Ily Shlamovitz 4, Eitan Tiomkin 4, Erez Yonay 7, Benny Sharir 4, Velizar Y Bumbarov 2
Published in: Viruses, 2019, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v11070633.
Author(s): Sushila Maan, Manjunatha N. Belaganahalli, Narender Singh Maan, Abraham C. Potgieter, Peter P. C. Mertens
Published in: Brazilian Journal of Microbiology, 50/1, 2019, Page(s) 287-296, ISSN 1517-8382
Publisher: Sociedade Braslleira de Microbiologia/Brazilian Society for Microbiology
DOI: 10.1007/s42770-018-0034-1
Author(s): Cecilia Aguilar-Vega; Belén Rivera; Javier Lucientes; Isabel Gutiérrez-Boada; José Manuel Sánchez-Vizcaíno
Published in: Parasites & Vectors14, 17563305, 2021, Page(s) 351, ISSN 1756-3305
Publisher: BioMed Central
DOI: 10.1186/s13071-021-04841-z
Author(s): Maude Jacquot, Kyriaki Nomikou, Massimo Palmarini, Peter Mertens, Roman Biek
Published in: Proceedings of the Royal Society B: Biological Sciences, 284/1864, 2017, Page(s) 20170919, ISSN 0962-8452
Publisher: Royal Society of London
DOI: 10.1098/rspb.2017.0919
Author(s): V. L. Fowler, E. L. A. Howson, J. Flannery, M. Romito, A. Lubisi, M. Agüero, P. Mertens, C. A. Batten, H. R. Warren, J. Castillo-Olivares
Published in: Transboundary and Emerging Diseases, 64/5, 2017, Page(s) 1579-1588, ISSN 1865-1674
Publisher: Blackwell-Wiss.-Verl
DOI: 10.1111/tbed.12549
Author(s): Cristina C. Celma, Meredith Stewart, Kerstin Wernike, Michael Eschbaumer, Lorenzo Gonzalez-Molleda, Emmanuel Breard, Claudia Schulz, Bernd Hoffmann, Andy Haegeman, Kris De Clercq, Stephan Zientara, Piet A. van Rijn, Martin Beer, Polly Roy
Published in: Journal of Virology, 91/1, 2016, ISSN 0022-538X
Publisher: American Society for Microbiology
DOI: 10.1128/JVI.01892-16
Author(s): Alkhamis MA, Fountain-Jones NM, Aguilar-Vega C, Sánchez-Vizcaíno JM
Published in: Ecol Appl ., 2021, ISSN 0021-8901
Publisher: Blackwell Publishing Inc.
DOI: 10.1002/eap.2407
Author(s): Ahmed Salem ElArbi, Yaghouba Kane, Raphaelle Metras, Pachka Hammami, Mamadou Ciss, Assane Beye, Renaud Lancelot, Adama Diallo, Andrea Apolloni
Published in: Frontiers in Veterinary Science, 6, 2019, ISSN 2297-1769
Publisher: Frontiers Media S.A
DOI: 10.3389/fvets.2019.00242
Author(s): Sophie Rossi, Thomas Balenghien, Cyril Viarouge, Eva Faure, Gina Zanella, Corinne Sailleau, Bruno Mathieu, Jean-Claude Delécolle, Camille Ninio, Claire Garros, Laëtitia Gardès, Christophe Tholoniat, Agnès Ariston, Dominique Gauthier, Stevan Mondoloni, Aurélie Barboiron, Maryline Pellerin, Philippe Gibert, Corinne Novella, Stéphane Barbier, Etienne Guillaumat, Stéphan Zientara, Damien Vitour
Published in: Viruses, 11/10, 2019, Page(s) 903, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v11100903
Author(s): Antoine Mignotte, Claire Garros, Laetitia Gardès, Thomas Balenghien, Maxime Duhayon, Ignace Rakotoarivony, Laura Tabourin, Léa Poujol, Bruno Mathieu, Adolfo Ibañez-Justicia, Ahmet Deniz, Aleksandar Cvetkovikj, Bethan V. Purse, David W. Ramilo, Despoina Stougiou, Doreen Werner, Dubravka Pudar, Dušan Petrić, Eva Veronesi, Frans Jacobs, Helge Kampen, Isabel Pereira da Fonseca, Javier Lucientes,
Published in: Parasites & Vectors, 13/1, 2020, ISSN 1756-3305
Publisher: BioMed Central
DOI: 10.1186/s13071-020-04114-1
Author(s): Cecilia Aguilar‐Vega, Eduardo Fernández‐Carrión, José M. Sánchez‐Vizcaíno
Published in: Transboundary and Emerging Diseases, 2019, ISSN 1865-1674
Publisher: Blackwell-Wiss.-Verl
DOI: 10.1111/tbed.13201
Author(s): Cecilia Aguilar-Vega, Eduardo Fernández-Carrión, Javier Lucientes, José Manuel Sánchez-Vizcaíno
Published in: PLOS ONE, 15/4, 2020, Page(s) e0232534, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0232534
Author(s): Curini V, Marcacci M, Tonelli A, Di Teodoro G, Di Domenico M, D'Alterio N, Portanti O, Ancora M, Savini G, Panfili M, Camma' C, Lorusso A.
Published in: Journal of Virological Methods., 2019, ISSN 0166-0934
Publisher: Elsevier BV
DOI: 10.1016/j.jviromet.2019.04.002.
Author(s): Eva Veronesi, Karin Darpel, Simon Gubbins, Carrie Batten, Kyriaki Nomikou, Peter Mertens, Simon Carpenter
Published in: Microorganisms, 8/6, 2020, Page(s) 851, ISSN 2076-2607
Publisher: MDPI
DOI: 10.3390/microorganisms8060851
Author(s): Mamadou Ciss, Biram Biteye, Assane Gueye Fall, Moussa Fall, Marie Cicille Ba Gahn, Louise Leroux & Andrea Apolloni
Published in: BMC Ecology, 2019, ISSN 1472-6785
Publisher: BioMed Central
DOI: 10.1186/s12898-019-0261-9
Author(s): Fairbanks EL, Brennan ML, Mertens PPC, Tildesley MJ, Daly JM.
Published in: ransbound Emerg Dis ., 2022, ISSN 1865-1674
Publisher: Blackwell-Wiss.-Verl
DOI: 10.1111/tbed.14420
Author(s): Fay, P.C.; Mohd Jaafar, F.; Batten, C.; Attoui, H.; Saunders, K.; Lomonossoff, G.P.; Reid, E.; Horton, D.; Maan, S.; Haig, D.; Daly, J.M.; Mertens, P.P.C.
Published in: Viruses, 2021, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13081455.
Author(s): Paulina Rajko-Nenow, Natalia Golender, Velizar Bumbarov, Hannah Brown, Lorraine Frost, Karin Darpel, Chandana Tennakoon, John Flannery, Carrie Batten
Published in: Microbiology Resource Announcements, 9/10, 2020, ISSN 2576-098X
Publisher: American Society for Microbiology
DOI: 10.1128/mra.01539-19
Author(s): Petra C. Fay, Houssam Attoui, Carrie Batten, Fauziah Mohd Jaafar, George P. Lomonossoff, Janet M. Daly, Peter P.C. Mertens
Published in: Vaccine: X, 2, 2019, Page(s) 100026, ISSN 2590-1362
Publisher: Elsevier
DOI: 10.1016/j.jvacx.2019.100026
Author(s): David J Pascall, View ORCID ProfileKyriaki Nomikou, Emmanuel Bréard, Stephan Zientara, Ana da Silva Filipe, View ORCID ProfileBernd Hoffmann, View ORCID ProfileMaude Jacquot, View ORCID ProfileJoshua B. Singer, View ORCID ProfileKris De Clercq, Anette Bøtner, Corinne Sailleau, Cyrille Viarouge, Carrie Batten, Giantonella Puggioni, Ciriaco Ligios, Giovanni Savini, Piet A. van Rijn, Peter PC
Published in: 2019
Publisher: BioRxiv
DOI: 10.1101/2019.12.11.872705