Understanding pathogen, livestock, environment interactions involving bluetongue virus

D12.5: Adaptation and maintenance of spatial data website to include PALE-Blu data (all Partners). (M12)

D3.2: Updated website with environmental and anthropogenic data archive and dissemination capabilities (Partner 1, 3, 6, 7, 10, 12). (M12)

Task 12.4: Establish and maintain project website(s) with regular updates over the project lifetime with all partners contributing new material, with review of the site at every consortium meeting. (all Partners) (M1 to M36)

D3.6: Archive of standardised and processed spatial data for use by WP1, WP3, & WP4 (Partner 1, 3, 6, 7, 10, 12). (M24)

D6.1: Protocol for collection, shipment and onward processing of Culicoides eggs (Partner 1,11,13,14,16,18). (M24)

D5.1: Serotype specific qRT-PCR for novel BTV serotypes (Partner 1, 2, 4, 5, 12, 16). (M18)

D3.4: Established friction surfaces and connectivity matrices (Partner 1, 3, 6, 7, 10, 12). (M24)

D3.3: Refined spatial epizone maps (Partner 1, 3, 6, 7, 10, 12). (M18)

D4.1: List of required environmental and landscape factors needed (Partner 3, 6, 7) (with WP3). (M3)

D5.2: Array based system for typing BTV (Partner 1, 4, 5). (M27)

D10.5: Report on early protection against one serotype in cattle by mono-serotype DISA vaccination (Partners 9). (M24).

D8.2: Reassortant viruses between conventional (e.g. BTV-1 or BTV-4) and novel/atypical strains (e.g. to explore the genetic basis for horizontal transmission (Partners 1, 2, 4, 5). (M18)

D8.1: An assessment of the the pathogenesis and horizontal transmission characteristics of BTV-8, BTV-26, and other ‘novel’ BTV strains in goats and sheep (Partners 2, 4, 5). (M18)

D3.1: A list of spatial data requirements from WP1, (Partners 1, 3, 4, 10). (M3)

D8.3: A mouse model for horizontal transmission of atypical BTV strains between mammalian hosts. (Partners 2). (M24)

D8.4: Identification of genome segments of the novel/atypical BTV strains/serotypes that support horizontal transmission in a mammalian host (Partners 1, 2, 4, 5). (M24)

D11.1: Identification of inhibitory doses of statin molecules on selected BTV strains in cell culture (Partner 2). (M24)

D6.2: Protocol for successful generation of primary cell cultures from different Culicoides spp. (Partner 1). (M27)

D4.3: Culicoides host maps as determined by available data (Partners 3, 6, 7). (M30)

D4.2: Spatial data base of vector distributions (Partner 3, 4, 6, 7, 12). (M12)

Author(s): Maude Jacquot, Kyriaki Nomikou, Massimo Palmarini, Peter Mertens, Roman Biek
Published in: Proceedings of the Royal Society B: Biological Sciences, Issue 284/1864, 2017, Page(s) 20170919, ISSN 0962-8452
DOI: 10.1098/rspb.2017.0919

Author(s): V. L. Fowler, E. L. A. Howson, J. Flannery, M. Romito, A. Lubisi, M. Agüero, P. Mertens, C. A. Batten, H. R. Warren, J. Castillo-Olivares
Published in: Transboundary and Emerging Diseases, Issue 64/5, 2017, Page(s) 1579-1588, ISSN 1865-1674
DOI: 10.1111/tbed.12549

Author(s): Cristina C. Celma, Meredith Stewart, Kerstin Wernike, Michael Eschbaumer, Lorenzo Gonzalez-Molleda, Emmanuel Breard, Claudia Schulz, Bernd Hoffmann, Andy Haegeman, Kris De Clercq, Stephan Zientara, Piet A. van Rijn, Martin Beer, Polly Roy
Published in: Journal of Virology, Issue 91/1, 2016, ISSN 0022-538X
DOI: 10.1128/JVI.01892-16