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Understanding pathogen, livestock, environment interactions involving bluetongue virus

Deliverables

Evaluated serotype specific ELISA

D55 Magplex Luminex assay system for detection and typing of BTV RNA Partner 1 12 16 M48

Protocol for collection, shipment and onward processing of Culicoides eggs

D6.1: Protocol for collection, shipment and onward processing of Culicoides eggs (Partner 1,11,13,14,16,18). (M24)

Identify cell proteins involved in competence of cell lines

D73 Identification of cellular proteins partners involved in competencerefractory status of cells lines and therefore identification of the mechanisms underlying competence Partners 1 2 M48

Viral vectored and sub-unit vaccine efficacy, mice

D104 Report on protection and immune response of AdV CAV2 and rMVA vaccines against several serotypes in IFNAR mice Partners 1 2 8 9 15 19 M30

High impact scientific publications

D127 High impact scientific publications all Partners M48

Description of ecological factors in vector populations and dispersion

D45 Description of ecological factors driving population structure and of natural barriers to vector dispersion Partner 3 6 7 12 M48

Levels of protection by statins in IFNAR mouse model

Determination of levels of protection afforded by statins that have been deemed as most efficient in cell cultures using IFNAR mouse model Partner 2 M48

Improved epidemiological models

D75 Improved epidemiological models integrating vector competence data Partners 6 7 10 12 M48

DISA cocktail efficacy cattle

D107 Report on protection in cattle by vaccination with a cocktail of DISA vaccines Partners 9 M48

Serotype specific qRT-PCR for novel BTV serotypes

D5.1: Serotype specific qRT-PCR for novel BTV serotypes (Partner 1, 2, 4, 5, 12, 16). (M18)

Validation of RNA microarrays

D53 Validation of the RNA microarrays Partner 1 4 5 P16 M27

Magplex / Luminex assay for detection and typing of BTV

D54 Diagnostic ELISA which has been evaluated Partner 1 5 16 M30

Established friction surfaces and connectivity matrices

D3.4: Established friction surfaces and connectivity matrices (Partner 1, 3, 6, 7, 10, 12). (M24)

Identify BTV protein domains restricting infection of Culicoides cells

D72 Identification of protein domains involved in restricting infection of Culicoides cells Partners 1 2 16 M48

Model for wind-borne introduction of flying insects into Europe

D46 A model for windborne introduction of flying insects into Europe to estimate the risk under specific climatic conditions Partner 3 6 7 12 M48

Determine possibility / frequency of reassortment between conventional and novel BTVs

D85 Determine possibility frequency of natural reassortment between conventional and novel BTVs Partners 1 2 5 M48

Characterisation of IFN response of ruminant endothelial cells to BTV-8 and BTV-26 (+/-saliva)

D91 Characterisation of the IFN response of ruminant endothelial cells to BTV8 and BTV26 in the presence or absence of Culicoides saliva Partner 10 and 16 M48

The effect of statins/inhibitory molecules on vaccination regimes

D115 Determination of effect of statinsinhibitory molecules on vaccination regimes Partner 2 8 M48

Refined spatial epizone maps

D3.3: Refined spatial epizone maps (Partner 1, 3, 6, 7, 10, 12). (M18)

List of required environmental and landscape factors

D4.1: List of required environmental and landscape factors needed (Partner 3, 6, 7) (with WP3). (M3)

Array system for typing BTV

D5.2: Array based system for typing BTV (Partner 1, 4, 5). (M27)

Phylogeographic analysis linking BTV diffusion to epizones and vector populations

D35 Phylogeographic analysis linking BTV diffusion to epizones and vector populations Partner 1 3 6 7 10 12 M48

BTV vaccine efficacy sheep

D106 Report on protection and immune response of AdV CAV2 rMVA and Ppastoris vaccines against several serotypes in sheep Partners 1 2 8 15 19 M48

DISA single BTV serotype protection

D105 Report on early protection against one serotype in cattle by monoserotype DISA vaccination Partners 9 M24

Antiviral / control strategies based on viral proteins involved in permissive / refractory status

D114 Development of potential antiviralcontrol strategies based on identification of viral proteins involved in permissiverefractory status Partner 2 8 M48

Reassortant strains between conventional and novel / atypical strains

D82 Reassortant viruses between conventional eg BTV1 or BTV4 and novelatypical strains eg to explore the genetic basis for horizontal transmission Partners 1 2 4 5 M18

Assess pathogenesis / horizontal transmission of BTV strains

D81 An assessment of the the pathogenesis and horizontal transmission characteristics of BTV8 BTV26 and other novel BTV strains in goats and sheep Partners 2 4 5 M18

Virus purification and sequencing/modelling of VP2 cleavage sites of 10 BTV strains

D92 Virus purification and sequencing modelling of VP2 cleavage sites of 10 BTV strains Partners 16 10 and 1 M48

List of spatial data required

D3.1: A list of spatial data requirements from WP1, (Partners 1, 3, 4, 10). (M3)

Histopathological changes in mice / sheep treated with statins and infected with BTV

D116 Determination of histopathological changes in mice andor sheep treated with selected statin molecules and infected with BTV Partner 2 M48

A mouse model for horizontal transmission of BTV

D83 A mouse model for horizontal transmission of atypical BTV strains between mammalian hosts Partners 2 M24

Standardisation of procedures for Culicoides infections

D74 Standardisation of procedures for the infection of adult Culicoides vectors and vectorderived cell lines to generate statistically robust data for vector competence Partners 1 2 16 M24

Virus-protein targets for novel anti-BTV strategies

D112 Identification of virusprotein targets for novel antiBTV strategies Partner 2 8 M24

Identification of BTV sequences influencing horizontal transmission in mammalian host

D86 Identification of BTV protein domains influencing horizontal transmission in a mammalian host Partners 1 2 5 M48

Attachment / uptake / replication characteristics for selected BTVs in different ruminant target cells

D95 Attachment uptake and replication characteristics for selected BTV strains in different ruminant target cells vascular endothelial cells monocytes Partner 16 and 10 M48

Identification of BTV genes that support horizontal transmission in mammalian host.

D84 Identification of genome segments of the novelatypical BTV strainsserotypes that support horizontal transmission in a mammalian host Partners 1 2 4 5 M24

Generation by reverse genetics and characterisation of cleavage resistant BTV strain(s)

D93 Generation by reverse genetics and characterisation of cleavage resistant BTV strains Partners 10 16 and 1 M48

Information/ advice for policy makers

D76 Information advice for policy makers concerning the biological characteristics of novel viral strains Partners 1 2 4 5 6 9 10 12 16 M1 to M48

Identification and characterisation of ruminant interferon stimulated genes that block BTV replication

D96 Identification and characterisation of ruminant ISGs that block BTV replication Partner 10 M48

Identification of statin doses that inhibit BTV in cell culture

D111 Identification of inhibitory doses of statin molecules on selected BTV strains in cell culture Partner 2 M24

Identify BTV genes restricting infection of Culicoides cells

D71 Identification of individual BTV genes involved in restricting infection of Culicoides cells Partners 1 2 16 M48

Infectivity assays in Culicoides (KC cells) and ruminant endothelial cells for select BTVs

D94 Infectivity assays in Culicoides KC cells and ruminant endothelial cells for selected BTV strains Partner 16 and 10 M48

Protocol for successful generation of primary cell cultures from different Culicoides spp.

D6.2: Protocol for successful generation of primary cell cultures from different Culicoides spp. (Partner 1). (M27)

Adaptation and maintenance of spatial data website to include PALE-Blu data

D125 Adaptation and maintenance of spatial data website to include PALEBlu data all Partners M12

Updated website with environment / anthropogenic data

D3.2: Updated website with environmental and anthropogenic data archive and dissemination capabilities (Partner 1, 3, 6, 7, 10, 12). (M12)

Project website

Task 124 Establish and maintain project websites with regular updates over the project lifetime with all partners contributing new material with review of the site at every consortium meeting all Partners M1 to M36

Archive of standardised and processed spatial data

D3.6: Archive of standardised and processed spatial data for use by WP1, WP3, & WP4 (Partner 1, 3, 6, 7, 10, 12). (M24)

Culicoides host maps

D4.3: Culicoides host maps as determined by available data (Partners 3, 6, 7). (M30)

Spatial data base of vector distributions

D4.2: Spatial data base of vector distributions (Partner 3, 4, 6, 7, 12). (M12)

Searching for OpenAIRE data...

Publications

Evaluation of an IGM ‐specific ELISA for early detection of bluetongue virus infections in domestic ruminants sera

Author(s): Emmanuel Bréard, Axel Gorlier, Cyril Viarouge, Fabien Donnet, Corinne Sailleau, Claudia Schulz, Bernd Hoffmann, Loic Comtet, Martin Beer, Stéphan Zientara, Damien Vitour
Published in: Transboundary and Emerging Diseases, 66/1, 2018, Page(s) 537-545, ISSN 1865-1674
Publisher: Blackwell-Wiss.-Verl
DOI: 10.1111/tbed.13060

Emerging vectorial diseases: West Nile fever, Bluetongue and Schmallenberg

Author(s): S Zientara 1, C Beck 1, S Lecollinet 1
Published in: Bulletin de l'Académie nationale de médecine, 2020, ISSN 0001-4079
Publisher: Elsevier BV
DOI: 10.1016/j.banm.2020.09.041

Contrasting selective patterns across the segmented genome of bluetongue virus in a global reassortment hotspot

Author(s): Maude Jacquot, Pavuluri P Rao, Sarita Yadav, Kyriaki Nomikou, Sushila Maan, Y Krishna Jyothi, Narasimha Reddy, Kalyani Putty, Divakar Hemadri, Karam P Singh, Narender Singh Maan, Nagendra R Hegde, Peter Mertens, Roman Biek
Published in: Virus Evolution, 5/2, 2019, ISSN 2057-1577
Publisher: Oxford University Press
DOI: 10.1093/ve/vez027

Global emergence and evolutionary dynamics of bluetongue virus

Author(s): Moh A. Alkhamis, Cecilia Aguilar-Vega, Nicholas M. Fountain-Jones, Kai Lin, Andres M. Perez & José M. Sánchez-Vizcaíno
Published in: Scientific Reports, 20452322, 2020, Page(s) 10:21677, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-78673-9

Identification of the Genome Segments of Bluetongue Virus Type 26/Type 1 Reassortants Influencing Horizontal Transmission in a Mouse Model. Viruses

Author(s): Houssam Attoui 1, Baptiste Monsion 1, Bernard Klonjkowski 1, Stéphan Zientara 1, Peter P C Mertens 2, Fauziah Mohd Jaafar 1
Published in: Viruses, 2021, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13112208

Western Bluetongue virus serotype 3 in Sardinia, diagnosis and characterization.

Author(s): Cappai S, Rolesu S, Loi F, Liciardi M, Leone A, Marcacci M, Teodori L, Mangone I, Sghaier S, Portanti O, Savini G, Lorusso A.
Published in: Transboundary and Emerging Diseases, 2019 May;66(3):1426-1431., 2019, Page(s) 1426-1431., ISSN 1865-1682
Publisher: Wiley
DOI: 10.1111/tbed.13156.

Presence of bluetongue and epizootic hemorrhagic disease viruses in Egypt in 2016 and 2017

Author(s): Sahar Ahmed, Mohamed Abd El-Fatah Mahmoud, Cyril Viarouge, Corinne Sailleau, Stephan Zientara, Emmanuel Breard
Published in: Infection, Genetics and Evolution, 73, 2019, Page(s) 221-226, ISSN 1567-1348
Publisher: Elsevier BV
DOI: 10.1016/j.meegid.2019.04.033

Identifying Spanish Areas at More Risk of Monthly BTV Transmission with a Basic Reproduction Number Approach

Author(s): Cecilia Aguilar-Vega, Jaime Bosch, Eduardo Fernández-Carrión, Javier Lucientes, José Manuel Sánchez-Vizcaíno
Published in: Viruses, 12/10, 2020, Page(s) 1158, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v12101158

Mapping livestock movements in Sahelian Africa

Author(s): Camille Jahel, Maxime Lenormand, Ismaila Seck, Andrea Apolloni, Ibra Toure, Coumba Faye, Baba Sall, Mbargou Lo, Cecile Squarzoni Diaw, Renaud Lancelot, Caroline Coste
Published in: Scientific Reports, 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-65132-8

Bluetongue Virus in France: An Illustration of the European and Mediterranean Context since the 2000s

Author(s): Cindy Kundlacz, Grégory Caignard, Corinne Sailleau, Cyril Viarouge, Lydie Postic, Damien Vitour, Stéphan Zientara, Emmanuel Breard
Published in: Viruses, 11/7, 2019, Page(s) 672, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v11070672

Modeling Arboviral Infection in Mice Lacking the Interferon Alpha/Beta Receptor

Author(s): Alejandro Marín-Lopez, Eva Calvo-Pinilla, Sandra Moreno, Sergio Utrilla-Trigo, Aitor Nogales, Alejandro Brun, Erol Fikrig, Javier Ortego
Published in: Viruses, 11/1, 2019, Page(s) 35, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v11010035

A low-passage insect-cell isolate of bluetongue virus uses a macropinocytosis-like entry pathway to infect natural target cells derived from the bovine host

Author(s): Lisa M. Stevens, Katy Moffat, Lyndsay Cooke, Kyriaki Nomikou, Peter P. C. Mertens, Terry Jackson, Karin E. Darpel
Published in: Journal of General Virology, 100/4, 2019, Page(s) 568-582, ISSN 0022-1317
Publisher: Society for General Microbiology
DOI: 10.1099/jgv.0.001240

“Frozen evolution” of an RNA virus suggests accidental release as a potential cause of arbovirus re-emergence

Author(s): David J. Pascall, Kyriaki Nomikou, Emmanuel Bréard, Stephan Zientara, Ana da Silva Filipe, Bernd Hoffmann, Maude Jacquot, Joshua B. Singer, Kris De Clercq, Anette Bøtner, Corinne Sailleau, Cyril Viarouge, Carrie Batten, Giantonella Puggioni, Ciriaco Ligios, Giovanni Savini, Piet A. van Rijn, Peter P. C. Mertens, Roman Biek, Massimo Palmarini
Published in: PLOS Biology, 18/4, 2020, Page(s) e3000673, ISSN 1545-7885
Publisher: Plos
DOI: 10.1371/journal.pbio.3000673

Environment, vector, or host? Using machine learning to untangle the mechanisms driving arbovirus outbreaks

Author(s): Moh A. Alkhamis,Nicholas M. Fountain-Jones,Cecilia Aguilar-Vega,José M. Sánchez-Vizcaíno
Published in: Ecological Applications, 19395582, 2021, Page(s) 31(7):e02407. 10.1002/eap.2407, ISSN 1939-5582
Publisher: Ecological Society of America
DOI: 10.1002/eap.2407

Evidence of reduced viremia, pathogenicity and vector competence in a re-emerging European strain of bluetongue virus serotype 8 in sheep.

Author(s): Flannery J, Sanz-Bernardo B, Ashby M, Brown H, Carpenter S, Cooke L, Corla A, Frost L, Gubbins S, Hicks H, Qureshi M, Rajko-Nenow P, Sanders C, Tully M, Bréard E, Sailleau C, Zientara S, Darpel K, Batten C.
Published in: Transboundary and Emerging Diseases, 2019, ISSN 1865-1682
Publisher: Wiley
DOI: 10.1111/tbed.13131.

"""Frozen evolution"" of an RNA virus suggests accidental release as a potential cause of arbovirus re-emergence."

Author(s): Pascall DJ, Nomikou K, Bréard E, Zientara S, Filipe ADS, Hoffmann B, Jacquot M, Singer JB, De Clercq K, Bøtner A, Sailleau C, Viarouge C, Batten C, Puggioni G, Ligios C, Savini G, van Rijn PA, Mertens PPC, Biek R, Palmarini M.
Published in: PLoS Biology, 2020, ISSN 1545-7885
Publisher: Public Library of Science
DOI: 10.1371/journal.pbio.3000673

African horse sickness in Thailand: Challenges of controlling an outbreak by vaccination,

Author(s): Castillo-Olivares, J.,
Published in: Equine Vet Journal, 2021, ISSN 2042-3306
Publisher: Wiley BEVA
DOI: 10.1111/evj.13353

Continuous Cell Lines from the European Biting Midge Culicoides nubeculosus (Meigen, 1830)

Author(s): Lesley Bell-Sakyi, Fauziah Mohd Jaafar, Baptiste Monsion, Lisa Luu, Eric Denison, Simon Carpenter, Houssam Attoui, Peter P. C. Mertens
Published in: Microorganisms, 8/6, 2020, Page(s) 825, ISSN 2076-2607
Publisher: MDPI.AG
DOI: 10.3390/microorganisms8060825

The Combined Expression of the Nonstructural Protein NS1 and the N-Terminal Half of NS2 (NS21-180) by ChAdOx1 and MVA Confers Protection against Clinical Disease in Sheep upon Bluetongue Virus Challenge

Author(s): Utrilla-Trigo S, Jiménez-Cabello L, Calvo-Pinilla E, Marín-López A, Lorenzo G, Sánchez-Cordón P, Moreno S, Benavides J, Gilbert S, Nogales A, Ortego J.
Published in: J Virol., 2022, ISSN 1098-5514
Publisher: American Society for Microbiology
DOI: 10.1128/jvi.01614-21

CD8 T Cell Responses to an Immunodominant Epitope within the Nonstructural Protein NS1 Provide Wide Immunoprotection against Bluetongue Virus in IFNAR −/− Mice

Author(s): Alejandro Marín-López, Eva Calvo-Pinilla, Diego Barriales, Gema Lorenzo, Alejandro Brun, Juan Anguita, Javier Ortego
Published in: Journal of Virology, 92/16, 2018, ISSN 0022-538X
Publisher: American Society for Microbiology
DOI: 10.1128/jvi.00938-18

Bluetongue Serotype 3 in Israel 2013–2018: Clinical Manifestations of the Disease and Molecular Characterization of Israeli Strains

Author(s): Natalia Golender, Velizar Bumbarov, Avi Eldar, Alessio Lorusso, Gabriel Kenigswald, Joseph Seffi Varsano, Dan David, Shani Schainin, Ilan Dagoni, Iosef Gur, Alon Kaplan, Anna Gorohov, Ori Koren, Eldad Oron, Yevgeny Khinich, Ily Sclamovich, Abraham Meir, Giovanni Savini
Published in: Frontiers in Veterinary Science, 7, 2020, ISSN 2297-1769
Publisher: Frontiers Media S.A.
DOI: 10.3389/fvets.2020.00112

Prospects of Next-Generation Vaccines for Bluetongue

Author(s): Piet A. van Rijn
Published in: Frontiers in Veterinary Science, 6, 2019, Page(s) 407-422, ISSN 2297-1769
Publisher: Frontiers Media S.A.
DOI: 10.3389/fvets.2019.00407

BTV antibody longevity in cattle five to eight years post BTV-8 vaccination

Author(s): Christina Ries 1, Martin Beer 1, Bernd Hoffmann 2
Published in: Vaccine, 2019, ISSN 0264-410X
Publisher: Elsevier BV
DOI: 10.1016/j.vaccine.2019.03.082.

Emergence of a Novel Reassortant Strain of Bluetongue Serotype 6 in Israel, 2017: Clinical Manifestations of the Disease and Molecular Characterization

Author(s): Natalia Golender 1, Avi Eldar 2, Marcelo Ehrlich 3, Yevgeny Khinich 2, Gabriel Kenigswald 4, Joseph Seffi Varsano 5, Shachar Ertracht 6, Itzik Abramovitz 4, Itay Assis 4, Ily Shlamovitz 4, Eitan Tiomkin 4, Erez Yonay 7, Benny Sharir 4, Velizar Y Bumbarov 2
Published in: Viruses, 2019, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v11070633.

Quantitative RT-PCR assays for identification and typing of the Equine encephalosis virus

Author(s): Sushila Maan, Manjunatha N. Belaganahalli, Narender Singh Maan, Abraham C. Potgieter, Peter P. C. Mertens
Published in: Brazilian Journal of Microbiology, 50/1, 2019, Page(s) 287-296, ISSN 1517-8382
Publisher: Sociedade Braslleira de Microbiologia/Brazilian Society for Microbiology
DOI: 10.1007/s42770-018-0034-1

A study of the composition of the Obsoletus complex and genetic diversity of Culicoides obsoletus populations in Spain.

Author(s): Cecilia Aguilar-Vega; Belén Rivera; Javier Lucientes; Isabel Gutiérrez-Boada; José Manuel Sánchez-Vizcaíno
Published in: Parasites & Vectors14, 17563305, 2021, Page(s) 351, ISSN 1756-3305
Publisher: BioMed Central
DOI: 10.1186/s13071-021-04841-z

Bluetongue virus spread in Europe is a consequence of climatic, landscape and vertebrate host factors as revealed by phylogeographic inference

Author(s): Maude Jacquot, Kyriaki Nomikou, Massimo Palmarini, Peter Mertens, Roman Biek
Published in: Proceedings of the Royal Society B: Biological Sciences, 284/1864, 2017, Page(s) 20170919, ISSN 0962-8452
Publisher: Royal Society of London
DOI: 10.1098/rspb.2017.0919

Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Assay for the Rapid Detection of African Horse Sickness Virus

Author(s): V. L. Fowler, E. L. A. Howson, J. Flannery, M. Romito, A. Lubisi, M. Agüero, P. Mertens, C. A. Batten, H. R. Warren, J. Castillo-Olivares
Published in: Transboundary and Emerging Diseases, 64/5, 2017, Page(s) 1579-1588, ISSN 1865-1674
Publisher: Blackwell-Wiss.-Verl
DOI: 10.1111/tbed.12549

Replication-Deficient Particles: New Insights into the Next Generation of Bluetongue Virus Vaccines

Author(s): Cristina C. Celma, Meredith Stewart, Kerstin Wernike, Michael Eschbaumer, Lorenzo Gonzalez-Molleda, Emmanuel Breard, Claudia Schulz, Bernd Hoffmann, Andy Haegeman, Kris De Clercq, Stephan Zientara, Piet A. van Rijn, Martin Beer, Polly Roy
Published in: Journal of Virology, 91/1, 2016, ISSN 0022-538X
Publisher: American Society for Microbiology
DOI: 10.1128/JVI.01892-16

Environment, vector, or host? Using machine learning to untangle the mechanisms driving arbovirus outbreaks

Author(s): Alkhamis MA, Fountain-Jones NM, Aguilar-Vega C, Sánchez-Vizcaíno JM
Published in: Ecol Appl ., 2021, ISSN 0021-8901
Publisher: Blackwell Publishing Inc.
DOI: 10.1002/eap.2407

PPR Control in a Sahelian Setting: What Vaccination Strategy for Mauritania?

Author(s): Ahmed Salem ElArbi, Yaghouba Kane, Raphaelle Metras, Pachka Hammami, Mamadou Ciss, Assane Beye, Renaud Lancelot, Adama Diallo, Andrea Apolloni
Published in: Frontiers in Veterinary Science, 6, 2019, ISSN 2297-1769
Publisher: Frontiers Media S.A
DOI: 10.3389/fvets.2019.00242

Red deer (Cervus elaphus) Did Not Play the Role of Maintenance Host for Bluetongue Virus in France: The Burden of Proof by Long-Term Wildlife Monitoring and Culicoides Snapshots

Author(s): Sophie Rossi, Thomas Balenghien, Cyril Viarouge, Eva Faure, Gina Zanella, Corinne Sailleau, Bruno Mathieu, Jean-Claude Delécolle, Camille Ninio, Claire Garros, Laëtitia Gardès, Christophe Tholoniat, Agnès Ariston, Dominique Gauthier, Stevan Mondoloni, Aurélie Barboiron, Maryline Pellerin, Philippe Gibert, Corinne Novella, Stéphane Barbier, Etienne Guillaumat, Stéphan Zientara, Damien Vitour
Published in: Viruses, 11/10, 2019, Page(s) 903, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v11100903

The tree that hides the forest: cryptic diversity and phylogenetic relationships in the Palaearctic vector Obsoletus/Scoticus Complex (Diptera: Ceratopogonidae) at the European level

Author(s): Antoine Mignotte, Claire Garros, Laetitia Gardès, Thomas Balenghien, Maxime Duhayon, Ignace Rakotoarivony, Laura Tabourin, Léa Poujol, Bruno Mathieu, Adolfo Ibañez-Justicia, Ahmet Deniz, Aleksandar Cvetkovikj, Bethan V. Purse, David W. Ramilo, Despoina Stougiou, Doreen Werner, Dubravka Pudar, Dušan Petrić, Eva Veronesi, Frans Jacobs, Helge Kampen, Isabel Pereira da Fonseca, Javier Lucientes,
Published in: Parasites & Vectors, 13/1, 2020, ISSN 1756-3305
Publisher: BioMed Central
DOI: 10.1186/s13071-020-04114-1

The possible route of introduction of bluetongue virus serotype 3 into Sicily by windborne transportation of infected Culicoides spp.

Author(s): Cecilia Aguilar‐Vega, Eduardo Fernández‐Carrión, José M. Sánchez‐Vizcaíno
Published in: Transboundary and Emerging Diseases, 2019, ISSN 1865-1674
Publisher: Blackwell-Wiss.-Verl
DOI: 10.1111/tbed.13201

A model for the assessment of bluetongue virus serotype 1 persistence in Spain

Author(s): Cecilia Aguilar-Vega, Eduardo Fernández-Carrión, Javier Lucientes, José Manuel Sánchez-Vizcaíno
Published in: PLOS ONE, 15/4, 2020, Page(s) e0232534, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0232534

Molecular typing of Bluetongue virus using the nCounter® analysis system platform.

Author(s): Curini V, Marcacci M, Tonelli A, Di Teodoro G, Di Domenico M, D'Alterio N, Portanti O, Ancora M, Savini G, Panfili M, Camma' C, Lorusso A.
Published in: Journal of Virological Methods., 2019, ISSN 0166-0934
Publisher: Elsevier BV
DOI: 10.1016/j.jviromet.2019.04.002.

Diversity of Transmission Outcomes Following Co-Infection of Sheep with Strains of Bluetongue Virus Serotype 1 and 8

Author(s): Eva Veronesi, Karin Darpel, Simon Gubbins, Carrie Batten, Kyriaki Nomikou, Peter Mertens, Simon Carpenter
Published in: Microorganisms, 8/6, 2020, Page(s) 851, ISSN 2076-2607
Publisher: MDPI
DOI: 10.3390/microorganisms8060851

Ecological niche modelling to estimate the distribution of Culicoides, potential vectors of bluetongue virus in Senegal

Author(s): Mamadou Ciss, Biram Biteye, Assane Gueye Fall, Moussa Fall, Marie Cicille Ba Gahn, Louise Leroux & Andrea Apolloni
Published in: BMC Ecology, 2019, ISSN 1472-6785
Publisher: BioMed Central
DOI: 10.1186/s12898-019-0261-9

Re-parameterisation of a mathematical model of African horse horse sickness virus using data from a systematic literature search.

Author(s): Fairbanks EL, Brennan ML, Mertens PPC, Tildesley MJ, Daly JM.
Published in: ransbound Emerg Dis ., 2022, ISSN 1865-1674
Publisher: Blackwell-Wiss.-Verl
DOI: 10.1111/tbed.14420

Serological Cross-Reactions between Expressed VP2 Proteins from Different Bluetongue Virus Serotypes.

Author(s): Fay, P.C.; Mohd Jaafar, F.; Batten, C.; Attoui, H.; Saunders, K.; Lomonossoff, G.P.; Reid, E.; Horton, D.; Maan, S.; Haig, D.; Daly, J.M.; Mertens, P.P.C.
Published in: Viruses, 2021, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13081455.

Complete Coding Sequence of a Novel Bluetongue Virus Isolated from a Commercial Sheeppox Vaccine

Author(s): Paulina Rajko-Nenow, Natalia Golender, Velizar Bumbarov, Hannah Brown, Lorraine Frost, Karin Darpel, Chandana Tennakoon, John Flannery, Carrie Batten
Published in: Microbiology Resource Announcements, 9/10, 2020, ISSN 2576-098X
Publisher: American Society for Microbiology
DOI: 10.1128/mra.01539-19

Bluetongue virus outer-capsid protein VP2 expressed in Nicotiana benthamiana raises neutralising antibodies and a protective immune response in IFNAR −/− mice

Author(s): Petra C. Fay, Houssam Attoui, Carrie Batten, Fauziah Mohd Jaafar, George P. Lomonossoff, Janet M. Daly, Peter P.C. Mertens
Published in: Vaccine: X, 2, 2019, Page(s) 100026, ISSN 2590-1362
Publisher: Elsevier
DOI: 10.1016/j.jvacx.2019.100026

Evolutionary stasis of an RNA virus indicates arbovirus re-emergence triggered by accidental release

Author(s): David J Pascall, View ORCID ProfileKyriaki Nomikou, Emmanuel Bréard, Stephan Zientara, Ana da Silva Filipe, View ORCID ProfileBernd Hoffmann, View ORCID ProfileMaude Jacquot, View ORCID ProfileJoshua B. Singer, View ORCID ProfileKris De Clercq, Anette Bøtner, Corinne Sailleau, Cyrille Viarouge, Carrie Batten, Giantonella Puggioni, Ciriaco Ligios, Giovanni Savini, Piet A. van Rijn, Peter PC
Published in: 2019
Publisher: BioRxiv
DOI: 10.1101/2019.12.11.872705