Understanding pathogen, livestock, environment interactions involving bluetongue virus

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Evaluated serotype specific ELISA

D55 Magplex Luminex assay system for detection and typing of BTV RNA Partner 1 12 16 M48

Protocol for collection, shipment and onward processing of Culicoides eggs

D6.1: Protocol for collection, shipment and onward processing of Culicoides eggs (Partner 1,11,13,14,16,18). (M24)

Identify cell proteins involved in competence of cell lines

D73 Identification of cellular proteins partners involved in competencerefractory status of cells lines and therefore identification of the mechanisms underlying competence Partners 1 2 M48

Viral vectored and sub-unit vaccine efficacy, mice

D104 Report on protection and immune response of AdV CAV2 and rMVA vaccines against several serotypes in IFNAR mice Partners 1 2 8 9 15 19 M30

High impact scientific publications

D127 High impact scientific publications all Partners M48

Description of ecological factors in vector populations and dispersion

D45 Description of ecological factors driving population structure and of natural barriers to vector dispersion Partner 3 6 7 12 M48

Levels of protection by statins in IFNAR mouse model

Determination of levels of protection afforded by statins that have been deemed as most efficient in cell cultures using IFNAR mouse model Partner 2 M48

Improved epidemiological models

D75 Improved epidemiological models integrating vector competence data Partners 6 7 10 12 M48

DISA cocktail efficacy cattle

D107 Report on protection in cattle by vaccination with a cocktail of DISA vaccines Partners 9 M48

Serotype specific qRT-PCR for novel BTV serotypes

D5.1: Serotype specific qRT-PCR for novel BTV serotypes (Partner 1, 2, 4, 5, 12, 16). (M18)

Validation of RNA microarrays

D53 Validation of the RNA microarrays Partner 1 4 5 P16 M27

Magplex / Luminex assay for detection and typing of BTV

D54 Diagnostic ELISA which has been evaluated Partner 1 5 16 M30

Established friction surfaces and connectivity matrices

D3.4: Established friction surfaces and connectivity matrices (Partner 1, 3, 6, 7, 10, 12). (M24)

Identify BTV protein domains restricting infection of Culicoides cells

D72 Identification of protein domains involved in restricting infection of Culicoides cells Partners 1 2 16 M48

Model for wind-borne introduction of flying insects into Europe

D46 A model for windborne introduction of flying insects into Europe to estimate the risk under specific climatic conditions Partner 3 6 7 12 M48

Determine possibility / frequency of reassortment between conventional and novel BTVs

D85 Determine possibility frequency of natural reassortment between conventional and novel BTVs Partners 1 2 5 M48

Characterisation of IFN response of ruminant endothelial cells to BTV-8 and BTV-26 (+/-saliva)

D91 Characterisation of the IFN response of ruminant endothelial cells to BTV8 and BTV26 in the presence or absence of Culicoides saliva Partner 10 and 16 M48

The effect of statins/inhibitory molecules on vaccination regimes

D115 Determination of effect of statinsinhibitory molecules on vaccination regimes Partner 2 8 M48

Refined spatial epizone maps

D3.3: Refined spatial epizone maps (Partner 1, 3, 6, 7, 10, 12). (M18)

List of required environmental and landscape factors

D4.1: List of required environmental and landscape factors needed (Partner 3, 6, 7) (with WP3). (M3)

Array system for typing BTV

D5.2: Array based system for typing BTV (Partner 1, 4, 5). (M27)

Phylogeographic analysis linking BTV diffusion to epizones and vector populations

D35 Phylogeographic analysis linking BTV diffusion to epizones and vector populations Partner 1 3 6 7 10 12 M48

BTV vaccine efficacy sheep

D106 Report on protection and immune response of AdV CAV2 rMVA and Ppastoris vaccines against several serotypes in sheep Partners 1 2 8 15 19 M48

DISA single BTV serotype protection

D105 Report on early protection against one serotype in cattle by monoserotype DISA vaccination Partners 9 M24

Antiviral / control strategies based on viral proteins involved in permissive / refractory status

D114 Development of potential antiviralcontrol strategies based on identification of viral proteins involved in permissiverefractory status Partner 2 8 M48

Reassortant strains between conventional and novel / atypical strains

D82 Reassortant viruses between conventional eg BTV1 or BTV4 and novelatypical strains eg to explore the genetic basis for horizontal transmission Partners 1 2 4 5 M18

Assess pathogenesis / horizontal transmission of BTV strains

D81 An assessment of the the pathogenesis and horizontal transmission characteristics of BTV8 BTV26 and other novel BTV strains in goats and sheep Partners 2 4 5 M18

Virus purification and sequencing/modelling of VP2 cleavage sites of 10 BTV strains

D92 Virus purification and sequencing modelling of VP2 cleavage sites of 10 BTV strains Partners 16 10 and 1 M48

List of spatial data required

D3.1: A list of spatial data requirements from WP1, (Partners 1, 3, 4, 10). (M3)

Histopathological changes in mice / sheep treated with statins and infected with BTV

D116 Determination of histopathological changes in mice andor sheep treated with selected statin molecules and infected with BTV Partner 2 M48

A mouse model for horizontal transmission of BTV

D83 A mouse model for horizontal transmission of atypical BTV strains between mammalian hosts Partners 2 M24

Standardisation of procedures for Culicoides infections

D74 Standardisation of procedures for the infection of adult Culicoides vectors and vectorderived cell lines to generate statistically robust data for vector competence Partners 1 2 16 M24

Virus-protein targets for novel anti-BTV strategies

D112 Identification of virusprotein targets for novel antiBTV strategies Partner 2 8 M24

Identification of BTV sequences influencing horizontal transmission in mammalian host

D86 Identification of BTV protein domains influencing horizontal transmission in a mammalian host Partners 1 2 5 M48

Attachment / uptake / replication characteristics for selected BTVs in different ruminant target cells

D95 Attachment uptake and replication characteristics for selected BTV strains in different ruminant target cells vascular endothelial cells monocytes Partner 16 and 10 M48

Identification of BTV genes that support horizontal transmission in mammalian host.

D84 Identification of genome segments of the novelatypical BTV strainsserotypes that support horizontal transmission in a mammalian host Partners 1 2 4 5 M24

Generation by reverse genetics and characterisation of cleavage resistant BTV strain(s)

D93 Generation by reverse genetics and characterisation of cleavage resistant BTV strains Partners 10 16 and 1 M48

Information/ advice for policy makers

D76 Information advice for policy makers concerning the biological characteristics of novel viral strains Partners 1 2 4 5 6 9 10 12 16 M1 to M48

Identification and characterisation of ruminant interferon stimulated genes that block BTV replication

D96 Identification and characterisation of ruminant ISGs that block BTV replication Partner 10 M48

Identification of statin doses that inhibit BTV in cell culture

D111 Identification of inhibitory doses of statin molecules on selected BTV strains in cell culture Partner 2 M24

Identify BTV genes restricting infection of Culicoides cells

D71 Identification of individual BTV genes involved in restricting infection of Culicoides cells Partners 1 2 16 M48

Infectivity assays in Culicoides (KC cells) and ruminant endothelial cells for select BTVs

D94 Infectivity assays in Culicoides KC cells and ruminant endothelial cells for selected BTV strains Partner 16 and 10 M48

Protocol for successful generation of primary cell cultures from different Culicoides spp.

D6.2: Protocol for successful generation of primary cell cultures from different Culicoides spp. (Partner 1). (M27)

Adaptation and maintenance of spatial data website to include PALE-Blu data

D125 Adaptation and maintenance of spatial data website to include PALEBlu data all Partners M12

Updated website with environment / anthropogenic data

D3.2: Updated website with environmental and anthropogenic data archive and dissemination capabilities (Partner 1, 3, 6, 7, 10, 12). (M12)

Project website

Task 124 Establish and maintain project websites with regular updates over the project lifetime with all partners contributing new material with review of the site at every consortium meeting all Partners M1 to M36

Archive of standardised and processed spatial data

D3.6: Archive of standardised and processed spatial data for use by WP1, WP3, & WP4 (Partner 1, 3, 6, 7, 10, 12). (M24)

Continuous cell lines from a European BTV-vector and a non-vector Culicoides species

D6.3: Continuous cell lines from at least one European BTV-vector and one non-vector Culicoides species (Partner 1). (M48)

New non-EU virus isolates

D2.3: Virus isolates from clinical samples from outbreaks, whenever feasible (Partners 1, 2, 4, 5, 11, 14, 15, 16, 17, 18, 19). (M48).

Genome sequence for EU BTVs

D1.3: Genome sequences for novel BTV outbreak strains (from clinical samples /insects /isolates) (Partners 1, 2, 4, 5, 8, 10, 12, 16). (M48).

Culicoides host maps

D4.3: Culicoides host maps as determined by available data (Partners 3, 6, 7). (M30)

Generate new EU virus isolates

D1.5: Virus isolates from clinical samples from outbreaks, whenever feasible (Partners 1, 2, 4, 5, 10, 12, 16). (M48).

Spacial/temporal data for non-EU BT outbreaks

D2.2: Spatial / temporal data for the incidence and spread of BT outbreaks (Partners 1, 2, 4, 5, 11, 14, 15, 16, 17, 18, 19) (M48).

Genetic structure maps and Culicoides microbiome

D4.4: Genetic structure maps and Culicoides microbiome composition (Partner 3, 6, 7, 12). (M48)

Sequence data for non-EU BTVs

D2.1: Genome sequences for novel BTV outbreak strains (from clinical samples /insects /isolates) (Partners 1, 2, 4, 5, 10, 11, 17) (M48).

Spacial /temporal data for EU BT outbreaks

D1.4: Spatial / temporal data for the incidence and spread of BT outbreaks (Partners 1, 2, 4, 5, 10, 12, 16) (M48).

Spatial data base of vector distributions

D4.2: Spatial data base of vector distributions (Partner 3, 4, 6, 7, 12). (M12)

Continuous cell lines from a Middle Eastern and an African BTV-vector Culicoides species

D6.4: Continuous cell lines from at least one Middle Eastern and one African BTV-vector Culicoides species (Partner 1). (M48)

Publikacje

Evaluation of an IGM ‐specific ELISA for early detection of bluetongue virus infections in domestic ruminants sera

Autorzy: Emmanuel Bréard, Axel Gorlier, Cyril Viarouge, Fabien Donnet, Corinne Sailleau, Claudia Schulz, Bernd Hoffmann, Loic Comtet, Martin Beer, Stéphan Zientara, Damien Vitour
Opublikowane w: Transboundary and Emerging Diseases, Numer 66/1, 2018, Strona(/y) 537-545, ISSN 1865-1674
Wydawca: Blackwell-Wiss.-Verl
DOI: 10.1111/tbed.13060

Clinical cases of Bluetongue serotype 8 in calves in France in the 2018-2019 winter.

Autorzy: Vinomack C, Rivière J, Bréard E, Viarouge C, Postic L, Zientara S, Vitour D, Belbis G, Spony V, Pagneux C, Sailleau C, Zanella G.
Opublikowane w: Transbound Emerg Dis., 2018, ISSN 1865-1674
Wydawca: Blackwell-Wiss.-Verl
DOI: 10.1016/j.jviromet.2019.04.002

Emerging vectorial diseases: West Nile fever, Bluetongue and Schmallenberg

Autorzy: S Zientara 1, C Beck 1, S Lecollinet 1
Opublikowane w: Bulletin de l'Académie nationale de médecine, 2020, ISSN 0001-4079
Wydawca: Elsevier BV
DOI: 10.1016/j.banm.2020.09.041

Contrasting selective patterns across the segmented genome of bluetongue virus in a global reassortment hotspot

Autorzy: Maude Jacquot, Pavuluri P Rao, Sarita Yadav, Kyriaki Nomikou, Sushila Maan, Y Krishna Jyothi, Narasimha Reddy, Kalyani Putty, Divakar Hemadri, Karam P Singh, Narender Singh Maan, Nagendra R Hegde, Peter Mertens, Roman Biek
Opublikowane w: Virus Evolution, Numer 5/2, 2019, ISSN 2057-1577
Wydawca: Oxford University Press
DOI: 10.1093/ve/vez027

Global emergence and evolutionary dynamics of bluetongue virus

Autorzy: Moh A. Alkhamis, Cecilia Aguilar-Vega, Nicholas M. Fountain-Jones, Kai Lin, Andres M. Perez & José M. Sánchez-Vizcaíno
Opublikowane w: Scientific Reports, Numer 10, 21677 (2020), 2020, Strona(/y) 10:21677, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-020-78673-9

Identification of the Genome Segments of Bluetongue Virus Type 26/Type 1 Reassortants Influencing Horizontal Transmission in a Mouse Model. Viruses

Autorzy: Houssam Attoui 1, Baptiste Monsion 1, Bernard Klonjkowski 1, Stéphan Zientara 1, Peter P C Mertens 2, Fauziah Mohd Jaafar 1
Opublikowane w: Viruses, 2021, ISSN 1999-4915
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13112208

"""Frozen evolution"" of an RNA virus suggests accidental release as a potential cause of arbovirus re-emergence."

Autorzy: Pascall DJ, Nomikou K, Bréard E, Zientara S, Filipe ADS, Hoffmann B, Jacquot M, Singer JB, De Clercq K, Bøtner A, Sailleau C, Viarouge C, Batten C, Puggioni G, Ligios C, Savini G, van Rijn PA, Mertens PPC, Biek R, Palmarini M.
Opublikowane w: Plos Biology, 2020, ISSN 1544-9173
Wydawca: Public Library of Science
DOI: 10.1371/journal.pbio.3000673

Western Bluetongue virus serotype 3 in Sardinia, diagnosis and characterization.

Autorzy: Cappai S, Rolesu S, Loi F, Liciardi M, Leone A, Marcacci M, Teodori L, Mangone I, Sghaier S, Portanti O, Savini G, Lorusso A.
Opublikowane w: Transboundary and Emerging Diseases, Numer 2019 May;66(3):1426-1431., 2019, Strona(/y) 1426-1431., ISSN 1865-1682
Wydawca: Wiley
DOI: 10.1111/tbed.13156.

Presence of bluetongue and epizootic hemorrhagic disease viruses in Egypt in 2016 and 2017

Autorzy: Sahar Ahmed, Mohamed Abd El-Fatah Mahmoud, Cyril Viarouge, Corinne Sailleau, Stephan Zientara, Emmanuel Breard
Opublikowane w: Infection, Genetics and Evolution, Numer 73, 2019, Strona(/y) 221-226, ISSN 1567-1348
Wydawca: Elsevier BV
DOI: 10.1016/j.meegid.2019.04.033

Recombinant Newcastle disease viruses with targets for PCR diagnostics for rinderpest and peste des petits ruminants

Autorzy: van Rijn PA, Boonstra J, van Gennip HGP.
Opublikowane w: J Virol Methods ., 2018, ISSN 0166-0934
Wydawca: Elsevier BV
DOI: 10.1016/j.jviromet.2018.06.007

Inhibition of Orbivirus Replication by Fluvastatin and Identification of the Key Elements of the Mevalonate Pathway Involved.

Autorzy: Mohd Jaafar, F.; Monsion, B.; Belhouchet, M.; Mertens, P.P.C.; Attoui, H.
Opublikowane w: Viruses, 2021, ISSN 1999-4915
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13081437

The genome segments of bluetongue virus differ in copy number in a host-specific manner.

Autorzy: 14. Moreau Y, Gil P, Exbrayat A, Rakotoarivony I, Bréard E, Sailleau C, Viarouge C, Zientara S, Savini G, Goffredo M, Mancini G, Loire E, Gutierrez S.
Opublikowane w: J.Virol, 2021, ISSN 1098-5514
Wydawca: American Society for Microbiology
DOI: 10.1128/jvi.01834-20

Inhibition of Orbivirus Replication by Aurintricarboxylic Acid

Autorzy: Alonso C, Utrilla-Trigo S, Calvo-Pinilla E, Jiménez-Cabello L, Ortego J, Nogales A.
Opublikowane w: Int J Mol Sci., 2020, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21197294

Identifying Spanish Areas at More Risk of Monthly BTV Transmission with a Basic Reproduction Number Approach

Autorzy: Cecilia Aguilar-Vega, Jaime Bosch, Eduardo Fernández-Carrión, Javier Lucientes, José Manuel Sánchez-Vizcaíno
Opublikowane w: Viruses, Numer 12/10, 2020, Strona(/y) 1158, ISSN 1999-4915
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v12101158

Mapping livestock movements in Sahelian Africa

Autorzy: Camille Jahel, Maxime Lenormand, Ismaila Seck, Andrea Apolloni, Ibra Toure, Coumba Faye, Baba Sall, Mbargou Lo, Cecile Squarzoni Diaw, Renaud Lancelot, Caroline Coste
Opublikowane w: Scientific Reports, Numer 10/1, 2020, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-020-65132-8

Bluetongue Disabled Infectious Single Animal (DISA) vaccine: Studies on the optimal route and dose in sheep.

Autorzy: van Rijn PA, Daus FJ, Maris-Veldhuis MA, Feenstra F, van Gennip RGP.
Opublikowane w: Vaccine, 2017, ISSN 0264-410X
Wydawca: Elsevier BV
DOI: 10.1016/j.vaccine.2016.11.081

Bluetongue Virus in France: An Illustration of the European and Mediterranean Context since the 2000s

Autorzy: Cindy Kundlacz, Grégory Caignard, Corinne Sailleau, Cyril Viarouge, Lydie Postic, Damien Vitour, Stéphan Zientara, Emmanuel Breard
Opublikowane w: Viruses, Numer 11/7, 2019, Strona(/y) 672, ISSN 1999-4915
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v11070672

Modeling Arboviral Infection in Mice Lacking the Interferon Alpha/Beta Receptor

Autorzy: Alejandro Marín-Lopez, Eva Calvo-Pinilla, Sandra Moreno, Sergio Utrilla-Trigo, Aitor Nogales, Alejandro Brun, Erol Fikrig, Javier Ortego
Opublikowane w: Viruses, Numer 11/1, 2019, Strona(/y) 35, ISSN 1999-4915
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v11010035

A low-passage insect-cell isolate of bluetongue virus uses a macropinocytosis-like entry pathway to infect natural target cells derived from the bovine host

Autorzy: Lisa M. Stevens, Katy Moffat, Lyndsay Cooke, Kyriaki Nomikou, Peter P. C. Mertens, Terry Jackson, Karin E. Darpel
Opublikowane w: Journal of General Virology, Numer 100/4, 2019, Strona(/y) 568-582, ISSN 0022-1317
Wydawca: Society for General Microbiology
DOI: 10.1099/jgv.0.001240

“Frozen evolution” of an RNA virus suggests accidental release as a potential cause of arbovirus re-emergence

Autorzy: David J. Pascall, Kyriaki Nomikou, Emmanuel Bréard, Stephan Zientara, Ana da Silva Filipe, Bernd Hoffmann, Maude Jacquot, Joshua B. Singer, Kris De Clercq, Anette Bøtner, Corinne Sailleau, Cyril Viarouge, Carrie Batten, Giantonella Puggioni, Ciriaco Ligios, Giovanni Savini, Piet A. van Rijn, Peter P. C. Mertens, Roman Biek, Massimo Palmarini
Opublikowane w: PLOS Biology, Numer 18/4, 2020, Strona(/y) e3000673, ISSN 1545-7885
Wydawca: Plos
DOI: 10.1371/journal.pbio.3000673

Environment, vector, or host? Using machine learning to untangle the mechanisms driving arbovirus outbreaks

Autorzy: Moh A. Alkhamis,Nicholas M. Fountain-Jones,Cecilia Aguilar-Vega,José M. Sánchez-Vizcaíno
Opublikowane w: Ecological Applications, Numer Vol.31,Numer 7, 2021, Strona(/y) 31(7):e02407. 10.1002/eap.2407, ISSN 1939-5582
Wydawca: Ecological Society of America
DOI: 10.1002/eap.2407

Virological, immunological and pathological findings of transplacentally transmitted bluetongue virus serotype 1 in IFNAR1-blocked mice during early and mid gestation

Autorzy: Saminathan M, Singh KP, Vineetha S, Maity M, Biswas SK, Manjunathareddy GB, Chauhan HC, Milton AAP, Ramakrishnan MA, Maan S, Maan NS, Hemadri D, Chandel BS, Gupta VK, Mertens PPC.
Opublikowane w: Sci Rep., 2020, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-020-58268-0

Evidence of reduced viremia, pathogenicity and vector competence in a re-emerging European strain of bluetongue virus serotype 8 in sheep.

Autorzy: Flannery J, Sanz-Bernardo B, Ashby M, Brown H, Carpenter S, Cooke L, Corla A, Frost L, Gubbins S, Hicks H, Qureshi M, Rajko-Nenow P, Sanders C, Tully M, Bréard E, Sailleau C, Zientara S, Darpel K, Batten C.
Opublikowane w: Transboundary and Emerging Diseases, 2019, ISSN 1865-1682
Wydawca: Wiley
DOI: 10.1111/tbed.13131.

African horse sickness in Thailand: Challenges of controlling an outbreak by vaccination,

Autorzy: Castillo-Olivares, J.,
Opublikowane w: Equine Vet Journal, 2021, ISSN 2042-3306
Wydawca: Wiley BEVA
DOI: 10.1111/evj.13353

A protective bivalent vaccine against Rift Valley fever and bluetongue. NPJ Vaccines.

Autorzy: Calvo-Pinilla E, Marín-López A, Moreno S, Lorenzo G, Utrilla-Trigo S, Jiménez-Cabello L, Benavides J, Nogales A, Blasco R, Brun A, Ortego J.
Opublikowane w: NPJ Vaccines, 2020, ISSN 2059-0105
Wydawca: Springer Nature
DOI: 10.1038/s41541-020-00218-y

Experimental infection of sheep, goats and cattle with a bluetongue virus serotype 4 field strain from Bulgaria, 2014

Autorzy: Schulz C, Sailleau C, Bréard E, Flannery J, Viarouge C, Zientara S, Beer M, Batten C, Hoffmann B.
Opublikowane w: Transbound Emerg Dis ., 2018, ISSN 1865-1674
Wydawca: Blackwell-Wiss.-Verl
DOI: 10.1111/tbed.12746

Pentavalent Disabled Infectious Single Animal (DISA)/DIVA Vaccine Provides Protection in Sheep and Cattle against Different Serotypes of Bluetongue Virus.

Autorzy: van Rijn, P.A.; Maris-Veldhuis, M.A.; Spedicato, M.; Savini, G.; van Gennip, R.G.P.
Opublikowane w: Vaccines, 2021, ISSN 2076-393X
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines9101150

High dispersal capacity of Culicoides obsoletus (Diptera: Ceratopogonidae), vector of bluetongue and Schmallenberg viruses, revealed by landscape genetic analyses.

Autorzy: 10. Mignotte, A., Garros, C., Dellicour, S., Jacquot M., Gilbert M., Gardès L., Balenghien T., Duhayon M., Rakotoarivony I., de Wavrechin M., Huber K.
Opublikowane w: Parasit Vectors, 2021, ISSN 1756-3305
Wydawca: BioMed Central
DOI: 10.1186/s13071-020-04522-3

The SUMOylation pathway suppresses arbovirus replication in Aedes aegypti cells.

Autorzy: Stokes S, Almire F, Tatham MH, McFarlane S, Mertens P, Pondeville E, Boutell C.
Opublikowane w: Plos Pathogens, 2020, ISSN 1553-7366
Wydawca: Public Library of Science
DOI: 10.1371/journal.ppat.1009134

An advection-deposition-survival model to assess the risk of introduction of vector-borne diseases through the wind: Application to bluetongue outbreaks in Spain

Autorzy: Fernández-Carrión E, Ivorra B, Ramos ÁM, Martínez-López B, Aguilar-Vega C, Sánchez-Vizcaíno JM.
Opublikowane w: Plos One, 2018, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0194573

Continuous Cell Lines from the European Biting Midge Culicoides nubeculosus (Meigen, 1830)

Autorzy: Lesley Bell-Sakyi, Fauziah Mohd Jaafar, Baptiste Monsion, Lisa Luu, Eric Denison, Simon Carpenter, Houssam Attoui, Peter P. C. Mertens
Opublikowane w: Microorganisms, Numer 8/6, 2020, Strona(/y) 825, ISSN 2076-2607
Wydawca: MDPI.AG
DOI: 10.3390/microorganisms8060825

CD8 T Cell Responses to an Immunodominant Epitope within the Nonstructural Protein NS1 Provide Wide Immunoprotection against Bluetongue Virus in IFNAR −/− Mice

Autorzy: Alejandro Marín-López, Eva Calvo-Pinilla, Diego Barriales, Gema Lorenzo, Alejandro Brun, Juan Anguita, Javier Ortego
Opublikowane w: Journal of Virology, Numer 92/16, 2018, ISSN 0022-538X
Wydawca: American Society for Microbiology
DOI: 10.1128/jvi.00938-18

Bluetongue Serotype 3 in Israel 2013–2018: Clinical Manifestations of the Disease and Molecular Characterization of Israeli Strains

Autorzy: Natalia Golender, Velizar Bumbarov, Avi Eldar, Alessio Lorusso, Gabriel Kenigswald, Joseph Seffi Varsano, Dan David, Shani Schainin, Ilan Dagoni, Iosef Gur, Alon Kaplan, Anna Gorohov, Ori Koren, Eldad Oron, Yevgeny Khinich, Ily Sclamovich, Abraham Meir, Giovanni Savini
Opublikowane w: Frontiers in Veterinary Science, Numer 7, 2020, ISSN 2297-1769
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fvets.2020.00112

Diagnostic DIVA tests accompanying the Disabled Infectious Single Animal (DISA) vaccine platform for African horse sickness

Autorzy: van Rijn PA, Maris-Veldhuis MA, Boonstra J, van Gennip RGP.
Opublikowane w: Vaccine, 2018, ISSN 0264-410X
Wydawca: Elsevier BV
DOI: 10.1016/j.vaccine.2018.05.044

Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): bluetongue.

Autorzy: EFSA Panel on Animal Health and Welfare (AHAW); More S, Bicout D, Bøtner A, Butterworth A, Depner K, Edwards S, Garin-Bastuji B, Good M, Gortázar Schmidt C, Michel V, Miranda MA, Nielsen SS, Raj M, Sihvonen L, Spoolder H, Stegeman JA, Thulke HH, Velarde A, Willeberg P, Winckler C, Mertens P, Savini G, Zientara S, Broglia A, Baldinelli F, Gogin A, Kohnle L, Calistri P.
Opublikowane w: EFSA Journal, 2017, ISSN 1831-4732
Wydawca: Wiley
DOI: 10.2903/j.efsa.2017.4957

Prospects of Next-Generation Vaccines for Bluetongue

Autorzy: Piet A. van Rijn
Opublikowane w: Frontiers in Veterinary Science, Numer 6, 2019, Strona(/y) 407-422, ISSN 2297-1769
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fvets.2019.00407

BTV antibody longevity in cattle five to eight years post BTV-8 vaccination

Autorzy: Christina Ries 1, Martin Beer 1, Bernd Hoffmann 2
Opublikowane w: Vaccine, 2019, ISSN 0264-410X
Wydawca: Elsevier BV
DOI: 10.1016/j.vaccine.2019.03.082.

Emergence of a Novel Reassortant Strain of Bluetongue Serotype 6 in Israel, 2017: Clinical Manifestations of the Disease and Molecular Characterization

Autorzy: Natalia Golender 1, Avi Eldar 2, Marcelo Ehrlich 3, Yevgeny Khinich 2, Gabriel Kenigswald 4, Joseph Seffi Varsano 5, Shachar Ertracht 6, Itzik Abramovitz 4, Itay Assis 4, Ily Shlamovitz 4, Eitan Tiomkin 4, Erez Yonay 7, Benny Sharir 4, Velizar Y Bumbarov 2
Opublikowane w: Viruses, 2019, ISSN 1999-4915
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v11070633.

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Bluetongue virus outer-capsid protein VP2 expressed in Nicotiana benthamiana raises neutralising antibodies and a protective immune response in IFNAR −/− mice

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Bluetongue Virus: From BTV-1 to BTV-27

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