Periodic Reporting for period 3 - TRANSVAC2 (European Vaccine Research and Development Infrastructure)
Periodo di rendicontazione: 2020-05-01 al 2021-10-31
- Develop a sustainable infrastructure accelerating vaccine R&D - construct an efficient and coordinated research and innovation environment by integrating key infrastructures and related initiatives from Europe and beyond, focused around the sustainable vaccine infrastructure:
-Stimulate technological innovation within Europe by fostering research by providing scientific and technical services to the vaccine R&D community:
-Strengthen and disseminate European vaccine expertise by offering classroom and laboratory training in vaccinology
-Perform joint research activities that continuously enhance and improve the services offered by the infrastructure.
-Maximise engagement of the European vaccine industry, including large pharmaceutical companies and SMEs
-Disseminate scientific information and communicate TRANSVAC2’s activities to the scientific community and general public:
-Take an active role in policy development, providing evidence-based recommendations to legislators and regulatory bodies.
- Up to now, 12 calls for trans-national access have been completed. In total 100 applications were submitted (including 10 resubmissions) by 65 research institutions and 20 SMEs from 18 countries within Europe and 6 overseas countries. 103 services were granted to 52 projects submitted by SMEs and research institutions.
- 11 calls were opened for series of training modules in vaccinology at leading European centres on vaccine R&D. Within these calls, 17 trainings were already conducted gathering in total 232 awarded applicants. In the last 18 months, 24 applications (18% of the total received) were from Eastern Europe. The second round of trainings is currently in progress, and a limited third round in planned for some highly-demanded courses.
- Some of the research activities (JRA) helping to improve services offered in TRANSVAC2 have been already successfully completed. Data generated in these tasks have been presented at international scientific meetings and published in peer reviewed journals. Additionally, all SOPs developed within the project shall be available for TRANSVAC partners and general public.
- A Board of Stakeholders (BoS) comprising representatives of policy and decision makers, industry associations and European infrastructures was established in August 2017. A first BoS workshop organized in June 2018 in Brussels was focused on identifying the gaps in existing European vaccine roadmaps (TRANSVAC and IPROVE). This meeting initated a process of updating TRANSVAC roadmap that was a basis of development of a strategic business plan for a sustainable vaccine R&D infrastructure in Europe. The TRANSVAC2 project has been extended until April 2023, and the continuation of the infrastructure beyond that horizon is being developed by the ongoing EC-project TRANSVAC-DS.
- Multiple promotional actions with the use of different communication tools were implemented to disseminate scientific information and communicate TRANSVAC2’s activities to the scientific community and general public:
o The project was presented (posters, presentations) and other promotional materials (flyers) were distributed in at least 59 scientific meetings (congresses, conferences and workshops).
o The outreach of the project was enhanced by project and partners’ websites as well as social media (Twitter, LinkedIn).
o a promotional movie (https://www.youtube.com/watch?v=2sadifFegks) and a story of TRANSVAC2 as a successful project (http://ec.europa.eu/research/infocentre/article_en.cfm?&artid=49836&caller=FP) are available to the general public.
- the TRANSVAC team has initiated and maintained a number of collaborations with other infrastructures and projects, to cooperate in dissemination activities. These include EC, IMI- funded projects, Research Infrastructures and Vaccine related initiatives and alliances. Consortium is constantly looking for new opportunities for collaboration.
The enormous burden exerted by the current COVID-19 pandemic has increased the pressure for the development of appropriate tools for disease control/management (prevention and treatment). Eight COVID-19-specific projects were granted in response to the emerging pandemic, three of which have been successfully completed. Additional 2 projects focused on Sars-Cov2 have been granted in recent TNA calls. TRANSVAC2-associated studies have produced 24 peer-reviewed publications. Experiments, production, and data analysis are ongoing in 33 approved projects at a wide range of stages in the development of vaccines targeted against parasitic, bacterial, and viral agents.
The TRANSVAC-DS project (Design study for a European vaccine infrastructure) aims to explore and prepare the further establishment of a sustainable vaccine infrastructure in Europe, and it further builds on the success and lessons learned of the TRANSVAC1 and TRANSVAC2 projects and proposes the establishment of a truly sustainable European vaccine infrastructure.