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Hybrid optical and optoacoustic endoscope for esophageal tracking.

Objective

More than 450.000 people are diagnosed with esophageal cancer (EC) each-year worldwide and approximately 400.000 die from the disease. Esophageal cancer is the eighth most commonly diagnosed cancer, but it is the sixth leading cause of cancer-related death, with incidence rates steeply rising. Risk factors, including gastroesophageal reflux disease and Barrett’s esophagus, may diagnostically implicate more than 300 million people worldwide. Nevertheless, the disease is detected late due to limitations in current diagnostic procedures leading to adverse prognosis and high treatment costs. ESOTRAC will change the landscape of esophageal diagnosis, over existing methods, based on cross-sectional optoacoustic and optical coherence endoscopy. The dual-modality system delivers a set of early-cancer imaging features necessary for improving early diagnosis, saving lives and leading to 3-5 Billion annual savings for the healthcare system. OCT provides micron scale subsurface morphological information based on photon scattering and optoacoustics provides deeper penetration and complementary pathophysiological features based on photon absorption. ESOTRAC develops novel photonic components (light sources, optical/optoacoustic scopes) and innovates novel medical system designs. Then, it performs pilot studies to investigate the functionality of the new endoscope and deliver a novel imaging-feature portfolio offering improved and earlier diagnosis. A central ESOTRAC ambition is that the new endoscope will become the new EC diagnostic standard by enabling quantitative and label-free three-dimensional endoscopy of early cancer with tremendous potential to impact esophageal care. ESOTRAC leverages European investment and know-how and strengthens the prospects of economic growth by leading the market position in endoscopic imaging.

Call for proposal

H2020-ICT-2016-1
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Coordinator

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Address
Ingolstadter Landstrasse 1
85764 Neuherberg
Germany
Activity type
Research Organisations
EU contribution
€ 1 129 709

Participants (8)

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
EU contribution
€ 343 265
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge
Activity type
Higher or Secondary Education Establishments
SONAXIS
France
EU contribution
€ 244 218,75
Address
Rue Emilie Du Chatelet 1
25000 Besancon
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
MEDIZINISCHE UNIVERSITAET WIEN
Austria
EU contribution
€ 527 500
Address
Spitalgasse 23
1090 Wien
Activity type
Higher or Secondary Education Establishments
RAYFOS LTD
United Kingdom
EU contribution
€ 372 500
Address
Winton House Winton Square
RG21 8EN Basingstoke
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ASCENION GmbH
Germany
EU contribution
€ 198 750
Address
Herzogstrasse 64
80803 Munich
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
AMPLITUDE
France
EU contribution
€ 264 501
Address
Avenue De Canteranne 11 Bat Meropa 6 Alee Des Lumieres Cite De La Photonique
33600 Pessac
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
DANMARKS TEKNISKE UNIVERSITET
Denmark
EU contribution
€ 371 250
Address
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby
Activity type
Higher or Secondary Education Establishments
STATICE SAS
France
EU contribution
€ 548 908,75
Address
Rue Thomas Edison 9
25000 Besancon
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)