Skip to main content

Multi-modal Optical Diagnostics for Ocular and Neurodegenerative Disease

Objective

The rising life expectancy of EU citizens is creating a dramatic increase in age-related degenerative diseases and associated healthcare costs. The MOON Project (Multi-modal Optical Diagnostics for Ocular and Neurodegenerative Disease) meets this societal challenge by applying photonics to diagnose age-related diseases of the eye and central nervous system. Consistent with the ICT-29-2016: Photonics KET 2016 Work Program, MOON will design and build a multi-band, multimodal and functional imaging platform combining label-free molecularly sensitive Raman spectroscopy with high speed and high-resolution Optical Coherence Tomography (OCT), for in-depth diagnostics of ocular and neurodegenerative diseases. MOON will enhance OCT – already the gold standard of retinal imaging - through the development of a disruptive laser technology that enables wide-field structural and functional imaging. MOON will establish a reference database for molecular biomarkers of addressed diseases that enables, for the first time, in-depth molecular-specific diagnosis of retinal diseases and neurodegenerative pathologies based on Raman spectroscopy. The MOON system will be validated in vivo in a clinical setting through close collaboration between clinicians and commercial partners. The clinical validation will establish the diagnostic accuracy of the multi-modal platform, while also verifying the ease-of-use needed for widespread adoption. MOON is driven by unmet medical user needs in diagnostic imaging with a clear business case addressing the highly promising ophthalmic market of early and in-depth molecularly sensitive diagnostics of retinal and neurodegenerative diseases. The three industrial partners cover the complete value/supply chain. MOON aims to bridge the gap between research and product development, thereby expediting the commercialization of the MOON technologies, strengthening the participating companies, and creating a competitive advantage for the European photonics market.

Field of science

  • /social sciences/economics and business/business and management/commerce
  • /medical and health sciences/basic medicine/pathology
  • /natural sciences/chemical sciences/analytical chemistry/spectroscopy
  • /social sciences/economics and business
  • /medical and health sciences/clinical medicine/ophthalmology
  • /natural sciences/physical sciences/optics/laser physics

Call for proposal

H2020-ICT-2016-1
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

MEDIZINISCHE UNIVERSITAET WIEN
Address
Spitalgasse 23
1090 Wien
Austria
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 800 202

Participants (5)

LEIBNIZ-INSTITUT FUER PHOTONISCHE TECHNOLOGIEN E.V.
Germany
EU contribution
€ 583 500
Address
Albert Einstein Strasse 9
07745 Jena
Activity type
Research Organisations
NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO
Netherlands
EU contribution
€ 510 812
Address
Anna Van Buerenplein 1
2595 DA Den Haag
Activity type
Research Organisations
CARL ZEISS AG
Germany
EU contribution
€ 693 120
Address
Carl Zeiss Strasse 22
73447 Oberkochen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
INNOLUME GMBH
Germany
EU contribution
€ 594 500
Address
Konrad-adenauer-allee 11
44263 Dortmund
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
HORIBA FRANCE SAS
France
EU contribution
€ 512 500
Address
Rue Du Canal 16-18
91160 Longjumeau
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)