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Multi-modal Optical Diagnostics for Ocular and Neurodegenerative Disease

Objective

The rising life expectancy of EU citizens is creating a dramatic increase in age-related degenerative diseases and associated healthcare costs. The MOON Project (Multi-modal Optical Diagnostics for Ocular and Neurodegenerative Disease) meets this societal challenge by applying photonics to diagnose age-related diseases of the eye and central nervous system. Consistent with the ICT-29-2016: Photonics KET 2016 Work Program, MOON will design and build a multi-band, multimodal and functional imaging platform combining label-free molecularly sensitive Raman spectroscopy with high speed and high-resolution Optical Coherence Tomography (OCT), for in-depth diagnostics of ocular and neurodegenerative diseases. MOON will enhance OCT – already the gold standard of retinal imaging - through the development of a disruptive laser technology that enables wide-field structural and functional imaging. MOON will establish a reference database for molecular biomarkers of addressed diseases that enables, for the first time, in-depth molecular-specific diagnosis of retinal diseases and neurodegenerative pathologies based on Raman spectroscopy. The MOON system will be validated in vivo in a clinical setting through close collaboration between clinicians and commercial partners. The clinical validation will establish the diagnostic accuracy of the multi-modal platform, while also verifying the ease-of-use needed for widespread adoption. MOON is driven by unmet medical user needs in diagnostic imaging with a clear business case addressing the highly promising ophthalmic market of early and in-depth molecularly sensitive diagnostics of retinal and neurodegenerative diseases. The three industrial partners cover the complete value/supply chain. MOON aims to bridge the gap between research and product development, thereby expediting the commercialization of the MOON technologies, strengthening the participating companies, and creating a competitive advantage for the European photonics market.

Call for proposal

H2020-ICT-2016-2017

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Sub call

H2020-ICT-2016-1

Coordinator

MEDIZINISCHE UNIVERSITAET WIEN
Net EU contribution
€ 812 702,00
Address
Spitalgasse 23
1090 Wien
Austria

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Region
Wien Wien
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,50

Participants (5)

LEIBNIZ-INSTITUT FUER PHOTONISCHE TECHNOLOGIEN E.V.
Germany
Net EU contribution
€ 583 500,00
Address
Albert Einstein Strasse 9
07745 Jena

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Region
Thüringen Thüringen Jena, Kreisfreie Stadt
Activity type
Research Organisations
Non-EU contribution
€ 0,00
NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO
Netherlands
Net EU contribution
€ 510 812,00
Address
Anna Van Buerenplein 1
2595 DA Den Haag

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Region
West-Nederland Zuid-Holland Agglomeratie ’s-Gravenhage
Activity type
Research Organisations
Non-EU contribution
€ 0,50
CARL ZEISS AG
Germany
Net EU contribution
€ 680 620,00
Address
Carl Zeiss Strasse 22
73447 Oberkochen

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Region
Baden-Württemberg Stuttgart Ostalbkreis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
INNOLUME GMBH
Germany
Net EU contribution
€ 594 500,00
Address
Konrad-adenauer-allee 11
44263 Dortmund

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Nordrhein-Westfalen Arnsberg Dortmund, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
HORIBA FRANCE SAS
France
Net EU contribution
€ 512 500,00
Address
14 Boulevard Thomas Gobert Passage Jobin Yvon Cs 4
91120 Palaiseau

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Region
Ile-de-France Ile-de-France Essonne
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00