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Setting an interdisciplinary/sectorial/international research network to explore dry storage as an alternative strategy for cells/germplasm biobanking

Objective

The number of biobanks for diagnostic/clinical/biodiversity preservation purposes is increasing exponentially, representing an economic burden for the EU. Cryopreservation (Liquid Nitrogen LN) is the only cells/gametes long-term repository method. LN storage is expensive though, requires dedicated facilities, is hazardous, carries pathogens and has high carbon footprint. DRYNET objective is to set an inter-sectorial/multidisciplinary/international network between EU academic (5), SME (3), the EU pan-Biobank, and international partners (Japan/Thailand), with the aim of sharing knowhow & expertise to lay down the theoretical and early empirical basis for the dry storage of cells/germplasm. DRYNET merges the partner’s expertise, theoretical/ biophysical/ mathematical modelling, cellular/ molecular/ insect biology, embryology, mechanical engineering into a coherent approach towards dry storage of cells/germplasm. International/inter-sectorial secondments, with meeting/workshop/summer school will be primary tools to implement our strategy for biobanking. Outreaching activities will guarantee public awareness of the project. DRYNET’s relies on water subtraction to induce a reversible block of metabolism, a survival strategy available in nature (anhydrobiosis). The work plan foresees the exploitation of natural xero-protectants (Late Embryogenesis Abundant proteins), loaded/expressed in gametes/cells, before drying. The best drying approaches, supported by theoretical/biophysical/math modelling, will be implemented by SMEs/academy partners. DRYNET will bring a simplification of currents practices, with cost and carbon footprint reduction, for the maintenance/shipping of biobanks. DRYNET will generate young scientists with transferable skills, ensuring career prospect in academia/industry. DRYNET strengthens the international/sectorial network between different disciplines, ensures long-term sustainability of the project, and boosts European competitiveness in biobanking.

Field of science

  • /engineering and technology/mechanical engineering
  • /natural sciences/chemical sciences/inorganic chemistry/inorganic compounds
  • /natural sciences/biological sciences/biochemistry/biomolecules/proteins
  • /social sciences/other social sciences/social sciences interdisciplinary/sustainable development
  • /medical and health sciences/clinical medicine/embryology

Call for proposal

H2020-MSCA-RISE-2016
See other projects for this call

Funding Scheme

MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)

Coordinator

UNIVERSITA DEGLI STUDI DI TERAMO
Address
Via Renato Balzarini 1 3 5 7
64100 Teramo
Italy
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 238 500

Participants (7)

UNIVERSITA DEGLI STUDI DI CAGLIARI
Italy
EU contribution
€ 112 500
Address
Via Universita 40
09124 Cagliari
Activity type
Higher or Secondary Education Establishments
UNIVERSIDAD DE BURGOS
Spain
EU contribution
€ 148 500
Address
Hospital Del Rey
09001 Burgos
Activity type
Higher or Secondary Education Establishments
AVANTEA srl
Italy
EU contribution
€ 27 000
Address
Via Cabrini 12
26100 Cremona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
BIOTALENTUM TUDASFEJLESZTO KFT
Hungary
EU contribution
€ 171 000
Address
Aulich Lajos Utca 26
2100 Goedoello
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
IMAGENE

Participation ended

France
EU contribution
€ 4 500
Address
2 Allee Du Doyen Georges Brus Parc Scientific Unitec
33600 Pessac
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC)

Participation ended

Austria
EU contribution
€ 0
Address
Neue Stiftingtalstrasse 2/B/6
8010 Graz
Activity type
Research Organisations
UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA
Italy
EU contribution
€ 63 000
Address
Via Universita 4
41121 Modena
Activity type
Higher or Secondary Education Establishments

Partners (2)

NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION
Japan
Address
3-1-1 Kannondai
3058517 Tsukuba Ibaraki
Activity type
Other
CHULALONGKORN UNIVERSITY
Thailand
Address
Phyathai Road 254 Pathumwan
10330 Bangkok
Activity type
Higher or Secondary Education Establishments