A new ICT-based device (RHEO-01) for fast point-of-care analysis of acute ischemic stroke and other emergency situations.

Informazioni relative al progetto

ERYTHROAG

ID dell’accordo di sovvenzione: 735480

DOI

10.3030/735480

Progetto chiuso

Data della firma CE 24 Luglio 2016

Data di avvio 1 Agosto 2016

Data di completamento 31 Gennaio 2017

Finanziato da

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Costo totale

€ 71 429,00

Contributo UE

€ 50 000,00

Coordinato da

RHEOFAST
France

Periodic Reporting for period 1 - ERYTHROAG (A new ICT-based device (RHEO-01) for fast point-of-care analysis of acute ischemic stroke and other emergency situations.)

Periodo di rendicontazione: 2016-08-01 al 2017-01-31

Sintesi del contesto e degli obiettivi generali del progetto

Stroke is the most frequent cause of long-term disability in Europe, mainly in middle-aged and elderly people. Stroke imposes a huge health care economic burden: >5B€/year in France.
RHEOFAST's RHEO-01 is a disruptive ICT-based smart decision support tool for medical emergency management. This tool will provide the physician with personalized patient’s health status assessment in a few minutes. It has three components which have to be evaluated:
- Fast, easily and highly reliable measurement of erythrocyte aggregation kinetics (EAK), a new biomarker of inflammation, and its medical relevance.
- Remote smart data processing and comparison with a reference dataset.
- Physician-friendly results for fast decision support.
This tool can be used in emergency vehicles and at the point of care.
In this phase 1, we evaluated whether RHEO-01 concept is feasible from a technical and a financial point of view and whether acute stroke management is the best indication for RHEO-01

Lavoro eseguito dall’inizio del progetto fino alla fine del periodo coperto dalla relazione e principali risultati finora ottenuti

With the most extensive clinical programme ever conducted and evaluating erythrocyte aggregation in clinical setting (1,300 measurements in 500 subjects) we were able to build and test a high-accuracy measurement of EAK, as well as to define the technical requirements for the smart data processing of EAK information. Our technique is well protected (pending PCT patents). Contrary to our initial hypothesis, both our clinical trials and our market analysis showed that the most promising indication for our product may likely be the management of acute chest pain suspected of heart attack. As for stroke management, timesaving is critical for improving the management and treatment of victims of heart attacks.

Progressi oltre lo stato dell’arte e potenziale impatto previsto (incluso l’impatto socioeconomico e le implicazioni sociali più ampie del progetto fino ad ora)

Cardiovascular disease remains the leading cause of death in Europe (42%), including coronary heart disease (20%) and stroke (10%). CVD is also the leading cause of years lived with disabilities in Europe.
By providing key, fast information for the appropriate orientation of patients suspected of heart attack, RHEO-01 might be able to improve patients survival, limit myocardial infarct size and, thereby chronic heart failure in these patients.

RHEOFAST