An Integrated Heart Model for the simulation of the cardiac function

Publicaciones

A Multiscale Poromechanics Model Integrating Myocardial Perfusion and the Epicardial Coronary Vessels

Autores: Nicolás Alejandro Barnafi Wittwer; Simone Di Gregorio; Luca Dede'; Paolo Zunino; Christian Vergara; Alfio Quarteroni
Publicado en: SIAM Journal on Applied Mathematics, Edición Vol. 82, Iss. 4 (2022), 2022, ISSN 0036-1399
Editor: Society for Industrial and Applied Mathematics
DOI: 10.1137/21m1424482

Iterative splitting schemes for a soft material poromechanics model

Autores: Jakub Wiktor Both; Nicolas A. Barnafi; Nicolas A. Barnafi; Florin Adrian Radu; Paolo Zunino; Alfio Quarteroni
Publicado en: Computer Methods in Applied Mechanics and Engineering, Edición 1, 2022, ISSN 0045-7825
Editor: Elsevier BV
DOI: 10.1016/j.cma.2021.114183

An oscillation-free fully staggered algorithm for velocity-dependent active models of cardiac mechanics

Autores: F. Regazzoni, A. Quarteroni
Publicado en: Computer Methods in Applied Mechanics and Engineering, Edición Volume 373, 1 January 2021, 113506, 2021, ISSN 0045-7825
Editor: Elsevier BV
DOI: 10.1016/j.cma.2020.113506

Integration of activation maps of epicardial veins in computational cardiac electrophysiology

Autores: Simone Stella; Christian Vergara; Massimiliano Maines; Domenico Catanzariti; Pasquale Claudio Africa; Cristina Dematte; Maurizio Centonze; Fabio Nobile; Maurizio Del Greco; Alfio Quarteroni; Alfio Quarteroni
Publicado en: Computers in Biology and Medicine, Edición Volume 127, December 2020, 104047, 2020, ISSN 0010-4825
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.compbiomed.2020.104047

3D–0D closed-loop model for the simulation of cardiac biventricular electromechanics

Autores: Roberto Piersanti; Francesco Regazzoni; Matteo Salvador; Antonio F. Corno; Luca Dede’; Christian Vergara; Alfio Quarteroni
Publicado en: Computer Methods in Applied Mechanics and Engineering, 2022, ISSN 0045-7825
Editor: Elsevier BV
DOI: 10.1016/j.cma.2022.114607

A physics-informed multi-fidelity approach for the estimation of differential equations parameters in low-data or large-noise regimes

Autores: Regazzoni, Francesco; Pagani, Stefano; Cosenza, Alessandro; Lombardi, Alessandro; Quarteroni, Alfio
Publicado en: Rendiconti Lincei. Matematica e Applicazioni, Edición Atti Accad. Naz. Lincei Cl. Sci. Fis. Mat. Natur. 32 (2021), no. 3, 2021, Página(s) 437–470, ISSN 1120-6330
Editor: Accademia Nazionale dei Lincei
DOI: 10.4171/rlm/943

Electromechanical modeling of human ventricles with ischemic cardiomyopathy: numerical simulations in sinus rhythm and under arrhythmia

Autores: Matteo Salvador; Marco Fedele; Pasquale Claudio Africa; Eric Sung; Luca Dedè; Adityo Prakosa; Jonathan Chrispin; Natalia A. Trayanova; Alfio Quarteroni
Publicado en: Computers in Biology and Medicine, Edición 4, 2021, ISSN 0010-4825
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.compbiomed.2021.104674

Computational electrophysiology of the coronary sinus branches based on electro-anatomical mapping for the prediction of the latest activated region

Autores: Vergara C., Stella S., Maines M., Africa P.C., Catanzariti D., Dematte' C., Centonze M., Nobile F., Quarteroni A., Del Greco M.,
Publicado en: Medical & Biological Engineering & Computing, Edición 60, 2022, Página(s) 2307-2319, ISSN 0140-0118
Editor: Institute of Electrical Engineers
DOI: 10.1007/s11517-022-02610-3

Mathematical analysis and numerical approximation of a general linearized poro-hyperelastic model

Autores: Nicolás Barnafi, Paolo Zunino, Luca Dedè, Alfio Quarteroni
Publicado en: Computers & Mathematics with Applications, 2020, Página(s) 1-27, ISSN 0898-1221
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.camwa.2020.07.025

Projection-based reduced order models for parameterized nonlinear time-dependent problems arising in cardiac mechanics

Autores: Cicci, Ludovica; Fresca, Stefania; Pagani, Stefano; Manzoni, Andrea; Quarteroni, Alfio
Publicado en: Mathematics in Engineering, Edición 2023, Volume 5, Edición 2, 2023, Página(s) 1-38, ISSN 2640-3501
Editor: AIMS press
DOI: 10.3934/mine.2023026

Image-Based Computational Hemodynamics Analysis of Systolic Obstruction in Hypertrophic Cardiomyopathy

Autores: Ivan Fumagalli; Piermario Vitullo; Christian Vergara; Marco Fedele; Antonio F. Corno; Sonia Ippolito; Roberto Scrofani; Alfio Quarteroni; Alfio Quarteroni
Publicado en: Frontiers in Physiology, 2022, ISSN 1664-042X
Editor: Frontiers Research Foundation
DOI: 10.3389/fphys.2021.787082

Data integration for the numerical simulation of cardiac electrophysiology.

Autores: Stefano Pagani; Luca Dedè; Andrea Manzoni; Alfio Quarteroni; Alfio Quarteroni
Publicado en: Pacing and Clinical Electrophysiology, Edición 5, 2021, ISSN 0147-8389
Editor: Blackwell Publishing Inc.
DOI: 10.1111/pace.14198

A comprehensive and biophysically detailed computational model of the whole human heart electromechanics

Autores: Fedele, Marco; Piersanti, Roberto; Regazzoni, Francesco; Salvador, Matteo; Africa, Pasquale; Bucelli, Michele; Zingaro, Alberto; Dede', Luca; Quarteroni, Alfio
Publicado en: Computer Methods in Applied Mechanics and Engineering, Edición Volume 410, 15 May 2023, 2023, ISSN 0045-7825
Editor: Elsevier BV
DOI: 10.1016/j.cma.2023.115983

Hemodynamics of the heart's left atrium based on a Variational Multiscale-LES numerical method

Autores: Alberto Zingaro; Luca Dede'; F. Menghini; Alfio Quarteroni; Alfio Quarteroni
Publicado en: European Journal of Mechanics - B/Fluids, Edición Volume 89, September–October 2021, 2021, Página(s) 380-400, ISSN 0997-7546
Editor: Elsevier BV
DOI: 10.1016/j.euromechflu.2021.06.014

A Computational Study of the Electrophysiological Substrate in Patients Suffering From Atrial Fibrillation

Autores: Pagani, S.; Dede', L.; Frontera, A.; Salvador, M.; Limite, L. R.; Manzoni, A.; Lipartiti, F.; Tsitsinakis, G.; Hadjis, A.; Della Bella, P.; Quarteroni, A.
Publicado en: Frontiers in Physiology, Edición vol. 10, 2021, ISSN 1664-042X
Editor: Frontiers Research Foundation
DOI: 10.3389/fphys.2021.673612

Active Force Generation in Cardiac Muscle Cells: Mathematical Modeling and Numerical Simulation of the Actin-Myosin Interaction

Autores: Francesco Regazzoni, Luca Dedè, Alfio Quarteroni
Publicado en: Vietnam Journal of Mathematics, 2020, ISSN 2305-221X
Editor: Springer Science + Business Media
DOI: 10.1007/s10013-020-00433-z

POD-Enhanced Deep Learning-Based Reduced Order Models for the Real-Time Simulation of Cardiac Electrophysiology in the Left Atrium.

Autores: Stefania Fresca; Andrea Manzoni; Luca Dedè; Alfio Quarteroni; Alfio Quarteroni
Publicado en: Frontiers in Physiology, Edición 6, 2021, ISSN 1664-042X
Editor: Frontiers Research Foundation
DOI: 10.3389/fphys.2021.679076

Multipatch Isogeometric Analysis for electrophysiology: Simulation in a human heart

Autores: Michele Bucelli, Matteo Salvador, Luca Dedè, Alfio Quarteroni
Publicado en: Computer Methods in Applied Mechanics and Engineering, Edición Volume 376, 1 April 2021, 2021, Página(s) 113666, ISSN 0045-7825
Editor: Elsevier BV
DOI: 10.1016/j.cma.2021.113666

Polygonal surface processing and mesh generation tools for the numerical simulation of the cardiac function

Autores: Marco Fedele, Alfio Quarteroni
Publicado en: International Journal for Numerical Methods in Biomedical Engineering, 2021, ISSN 2040-7947
Editor: John Wiley & Sons Ltd
DOI: 10.1002/cnm.3435

Enabling forward uncertainty quantification and sensitivity analysis in cardiac electrophysiology by reduced order modeling and machine learning.

Autores: Stefano Pagani; Andrea Manzoni
Publicado en: International Journal for Numerical Methods in Biomedical Engineering, 2021, ISSN 2040-7947
Editor: John Wiley & Sons Ltd
DOI: 10.1002/cnm.3450

Deep learning-based reduced order models in cardiac electrophysiology

Autores: Fresca, S.; Manzoni, A.; Dedè, L.; Quarteroni, A.
Publicado en: PLOS One, Edición 15, 10, 2020, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0239416

A computational model applied to myocardial perfusion in the human heart: From large coronaries to microvasculature

Autores: Di Gregorio Simone, Fedele Marco, Pontone Gianluca, Corno,Antonio, Zunino Paolo, Vergara Christian, Quarteroni Alfio
Publicado en: JOURNAL OF COMPUTATIONAL PHYSICS, Edición 424, 2021, Página(s) 109836-109859, ISSN 0021-9991
Editor: Academic Press
DOI: 10.1016/j.jcp.2020.109836

PDE-Aware Deep Learning for Inverse Problems in Cardiac Electrophysiology

Autores: Riccardo Tenderini; Stefano Pagani; Alfio Quarteroni; Simone Deparis
Publicado en: SIAM Journal on Scientific Computing, Edición Vol. 44, Iss. 3 (2022), 2022, ISSN 1064-8275
Editor: Society for Industrial and Applied Mathematics
DOI: 10.1137/21m1438529

Fluid-structure interaction analysis of transcatheter aortic valve implantation

Autores: Fumagalli, Ivan; Polidori, Rebecca; Renzi, Francesca; Fusini, Laura; Quarteroni, Alfio; Pontone, Gianluca; Vergara, Christian
Publicado en: International Journal for Numerical Methods in Biomedical Engineering, Edición e3704, 2023, ISSN 2040-7947
Editor: Wiley
DOI: 10.1002/cnm.3704

An image-based computational hemodynamics study of the Systolic Anterior Motion of the mitral valve

Autores: Ivan Fumagalli, Marco Fedele, Christian Vergara, Luca Dedè, Sonia Ippolito, Francesca Nicolò, Carlo Antona, Roberto Scrofani, Alfio Quarteroni
Publicado en: Computers in Biology and Medicine, Edición Volume 123, August 2020, 103922, 2020, ISSN 0010-4825
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.compbiomed.2020.103922

lifex: A flexible, high performance library for the numerical solution of complex finite element problems

Autores: Pasquale Claudio Africa
Publicado en: SoftwareX, Edición vol. 23 (2023), 2023, ISSN 2352-7110
Editor: Elsevier
DOI: 10.1016/j.softx.2022.101252

A machine learning method for real-time numerical simulations of cardiac electromechanics

Autores: F. Regazzoni; M. Salvador; L. Dede’; A. Quarteroni
Publicado en: COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING, 2022, ISSN 0045-7825
Editor: Elsevier BV
DOI: 10.1016/j.cma.2022.114825

The role of mechano-electric feedbacks and hemodynamic coupling in scar-related ventricular tachycardia

Autores: Matteo Salvador; Francesco Regazzoni; Stefano Pagani; Luca Dede'; Natalia Trayanova; Alfio Quarteroni
Publicado en: Computers in Biology and Medicine, Edición 6, 2022, ISSN 0010-4825
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.compbiomed.2021.105203

Partitioned and monolithic algorithms for the numerical solution of cardiac fluid-structure interaction

Autores: Michele Bucelli, Luca Dede', Alfio Quarteroni, Christian Vergara
Publicado en: Communications in Computational Physics, Edición 32 (2022), 2022, Página(s) 1217-1256, ISSN 1815-2406
Editor: Global Science Press
DOI: 10.4208/cicp.oa-2021-0243

lifex-fiber: an open tool for myofibers generation in cardiac computational models

Autores: Pasquale Claudio Africa, Roberto Piersanti, Marco Fedele, Luca Dede’ , Alfio Quarteroni
Publicado en: BMC Bioinformatics, Edición 24 (1):143, 2023, ISSN 1471-2105
Editor: BioMed Central
DOI: 10.1186/s12859-023-05260-w

A mathematical model that integrates cardiac electrophysiology, mechanics and fluid dynamics: application to the human left heart

Autores: Michele Bucelli; Alberto Zingaro; Pasquale Claudio Africa; Ivan Fumagalli; Luca Dede'; Alfio Quarteroni
Publicado en: International Journal for Numerical Methods in Biomedical Engineering, Edición 1, 2023, Página(s) Volume39, Edición3, March 2023, e3678, ISSN 2040-7947
Editor: Wiley
DOI: 10.1002/cnm.3678

The Impact of Left Atrium Appendage Morphology on Stroke Risk Assessment in Atrial Fibrillation: A Computational Fluid Dynamics Study

Autores: Alessandro Masci, Lorenzo Barone, Luca Dedè, Marco Fedele, Corrado Tomasi, Alfio Quarteroni, Cristiana Corsi
Publicado en: Frontiers in Physiology, Edición 9, 2019, ISSN 1664-042X
Editor: Frontiers Research Foundation
DOI: 10.3389/fphys.2018.01938

Isogeometric Analysis of the electrophysiology in the human heart: Numerical simulation of the bidomain equations on the atria

Autores: Luca Pegolotti, Luca Dedè, Alfio Quarteroni
Publicado en: Computer Methods in Applied Mechanics and Engineering, Edición 343, 2019, Página(s) 52-73, ISSN 0045-7825
Editor: Elsevier BV
DOI: 10.1016/j.cma.2018.08.032

A transmurally heterogeneous orthotropic activation model for ventricular contraction and its numerical validation

Autores: Luca Barbarotta, Simone Rossi, Luca Dedè, Alfio Quarteroni
Publicado en: International Journal for Numerical Methods in Biomedical Engineering, Edición 34/12, 2018, Página(s) e3137, ISSN 2040-7939
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/cnm.3137

A monolithic algorithm for the simulation of cardiac electromechanics in the human left ventricle

Autores: Antonello Gerbi, Luca Dede’, Alfio Quarteroni
Publicado en: Mathematics in Engineering, Edición 1/1, 2018, Página(s) 1-37, ISSN 2640-3501
Editor: AIMS Press
DOI: 10.3934/mine.2018.1.1

Numerical approximation of parametrized problems in cardiac electrophysiology by a local reduced basis method

Autores: Stefano Pagani, Andrea Manzoni, Alfio Quarteroni
Publicado en: Computer Methods in Applied Mechanics and Engineering, Edición 340, 2018, Página(s) 530-558, ISSN 0045-7825
Editor: Elsevier BV
DOI: 10.1016/j.cma.2018.06.003

Biophysically detailed mathematical models of multiscale cardiac active mechanics

Autores: Francesco Regazzoni, Luca Dedè, Alfio Quarteroni
Publicado en: PLOS Computational Biology, 2020, ISSN 1553-734X
Editor: Public Library of Science

Computational fluid dynamics of blood flow in an idealized left human heart

Autores: Luca Dedè, Filippo Menghini, Alfio Quarteroni
Publicado en: International Journal for Numerical Methods in Biomedical Engineering, 2019, ISSN 2040-7939
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/cnm.3287

An intergrid transfer operator using radial basis functions with application to cardiac electromechanics

Autores: Matteo Salvador, Luca Dede', Alfio Quarteroni
Publicado en: Computational Mechanics, Edición Volume 66, Edición 1, July 2020, 2020, ISSN 0178-7675
Editor: Springer Verlag

Machine learning of multiscale active force generation models for the efficient simulation of cardiac electromechanics

Autores: F. Regazzoni, L. Dedè, A. Quarteroni
Publicado en: Computer Methods in Applied Mechanics and Engineering, Edición 370, 2020, Página(s) 113268, ISSN 0045-7825
Editor: Elsevier BV
DOI: 10.1016/j.cma.2020.113268

Mathematical and numerical models for the cardiac electromechanical function

Autores: Luca Dedè; Alfio Quarteroni; Francesco Regazzoni
Publicado en: Atti Accademia Nazionale dei Lincei, Edición Classe Scienze Fisiche Matematiche Naturali 32 (2021), no. 2, 2021, Página(s) 233-272, ISSN 1120-6330
Editor: Accademia Nazionale dei Lincei
DOI: 10.4171/rlm/935

Modeling the cardiac electromechanical function: A mathematical journey

Autores: Alfio Quarteroni; Luca Dedè; Francesco Regazzoni
Publicado en: Bulletin of the American Mathematical Society, Edición 59 (2022), 2022, Página(s) 371-403, ISSN 0273-0979
Editor: American Mathematical Society
DOI: 10.1090/bull/1738

A stable loosely-coupled scheme for cardiac electro-fluid-structure interaction

Autores: Michele Bucelli , Martin Geraint Gabriel , Alfio Quarteroni , Giacomo Gigante , Christian Vergara
Publicado en: Journal of Computational Physics, Edición Volume 490, 1 October 2023, 112326, 2023, ISSN 0021-9991
Editor: Academic Press
DOI: 10.1016/j.jcp.2023.112326

Deep-HyROMnet: A Deep Learning-Based Operator Approximation for Hyper-Reduction of Nonlinear Parametrized PDEs

Autores: Cicci, Ludovica; Fresca, Stefania; Manzoni, Andrea
Publicado en: Journal of Scientific Computing, Edición 93, Article number: 57 (2022), 2022, ISSN 0885-7474
Editor: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s10915-022-02001-8

Efficient and certified solution of parametrized one-way coupled problems through DEIM-based data projection across non-conforming interfaces

Autores: Elena Zappon, Andrea Manzoni, Alfio Quarteroni
Publicado en: Advances in Computational Mathematics, Edición 49, 21, 2023, ISSN 1019-7168
Editor: Kluwer Academic Publishers
DOI: 10.48550/arxiv.2203.09226

A cardiac electromechanical model coupled with a lumped-parameter model for closed-loop blood circulation

Autores: F. Regazzoni; M. Salvador; P.C. Africa; M. Fedele; L. Dedè; A. Quarteroni
Publicado en: Journal of Computational Physics, Edición 4, 2022, ISSN 0021-9991
Editor: Academic Press
DOI: 10.1016/j.jcp.2022.111083

Modeling cardiac muscle fibers in ventricular and atrial electrophysiology simulations

Autores: Roberto Piersanti, Pasquale C. Africa, Marco Fedele, Christian Vergara, Luca Dedè, Antonio F. Corno, Alfio Quarteroni
Publicado en: Computer Methods in Applied Mechanics and Engineering, Edición 373, 2021, Página(s) 113468, ISSN 0045-7825
Editor: Elsevier BV
DOI: 10.1016/j.cma.2020.113468

A geometric multiscale model for the numerical simulation of blood flow in the human left heart

Autores: Alberto Zingaro; Ivan Fumagalli; Luca Dede; Marco Fedele; Pasquale C. Africa; Antonio F. Corno; Alfio Quarteroni
Publicado en: Discrete and Continuous Dynamical Systems - Series S, Edición 5, 2022, ISSN 1937-1632
Editor: American Institute of Mathematical Sciences
DOI: 10.3934/dcdss.2022052

Segregated algorithms for the numerical simulation of cardiac electromechanics in the left human ventricle

Autores: L. Dede', A. Gerbi, A. Quarteroni
Publicado en: The Mathematics of Mechanobiology, 2020, Página(s) 81--116, ISBN 978-3-030-45196-7
Editor: Springer Verlag
DOI: 10.1007/978-3-030-45197-4_3

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