Advanced clinical photoacoustic imaging systems based on optical microresonator detection

Información del proyecto

Photoclin

Identificador del acuerdo de subvención: 741149

DOI

10.3030/741149

Proyecto cerrado

Fecha de la firma de la CE 21 Agosto 2017

Fecha de inicio 1 Diciembre 2017

Fecha de finalización 30 Abril 2025

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 2 163 061,00

Aportación de la UE

€ 2 163 061,00

Coordinado por

UNIVERSITY COLLEGE LONDON
United Kingdom

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (33)

A fast all-optical 3D photoacoustic scanner for clinical vascular imaging

Autores: N. T. Huynh, E. Zhang, O. Francies, F. Kuklis, T. Allen, J. Zhu, O. Abeyakoon, F. Lucka, M. Betcke, J. Jaros, S. Arridge, B. Cox, A. A. Plumb, P. Beard
Publicado en: Nature Biomedical Engineering, Edición 9, 2025, Página(s) 638-655, ISSN 2157-846X
Editor: Springer Science and Business Media LLC
DOI: 10.1038/s41551-024-01247-x

Multimodal optical ultrasound imaging: Real-time imaging under concurrent CT or MRI

Autores: Fraser T. Watt, Vivek Muthurangu, Jennifer Steeden, Eleanor C. Mackle, Adrien E. Desjardins, Edward Z. Zhang, Paul C. Beard, Erwin J. Alles
Publicado en: APL Photonics, Edición 9, 2025, ISSN 2378-0967
Editor: AIP Publishing
DOI: 10.1063/5.0225554

Analysis of the Directivity of Glass-Etalon Fabry–Pérot Ultrasound Sensors

Autores: Danny R. Ramasawmy, Eleanor Martin, James A. Guggenheim, Edward Z. Zhang, Paul C. Beard, Bradley E. Treeby, Ben T. Cox
Publicado en: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Edición 66/9, 2019, Página(s) 1504-1513, ISSN 0885-3010
Editor: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tuffc.2019.2921735

Sustained real-time and video-rate interventional optical ultrasound imaging

Autores: Robert M. Stafford-Williams, Richard J. Colchester, Semyon Bodian, Seán Cardiff, Efthymios Maneas, Edward Z. Zhang, Paul C. Beard, Manish K. Tiwari, Adrien E. Desjardins, Erwin J. Alles
Publicado en: Journal of Biomedical Optics, Edición 30, 2025, ISSN 1083-3668
Editor: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.30.3.036005

Freehand and video-rate all-optical ultrasound imaging

Autores: Erwin J. Alles, Eleanor C. Mackle, Sacha Noimark, Edward Z. Zhang, Paul C. Beard, Adrien E. Desjardins
Publicado en: Ultrasonics, Edición 116, 2025, Página(s) 106514, ISSN 0041-624X
Editor: Elsevier BV
DOI: 10.1016/j.ultras.2021.106514

Mitigating the Limited View Problem in Photoacoustic Tomography for a Planar Detection Geometry by Regularized Iterative Reconstruction

Autores: Jiaqi Zhu, Nam Huynh, Olumide Ogunlade, Rehman Ansari, Felix Lucka, Ben Cox, Paul Beard
Publicado en: IEEE Transactions on Medical Imaging, Edición 42, 2023, Página(s) 2603-2615, ISSN 0278-0062
Editor: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tmi.2023.3271390

High-resolution imaging of ultrasonic fields through a multimode optical fiber

Autores: Benjamin Keenlyside, Dylan Marques, David B. Phillips, Edward Zhang, Paul Beard, James Guggenheim
Publicado en: Physical Review Applied, Edición 24, 2025, ISSN 2331-7019
Editor: American Physical Society (APS)
DOI: 10.1103/nrzh-hqsh

Single-shot hybrid photoacoustic-fluorescent microendoscopy through a multimode fiber with wavefront shaping

Autores: Sylvain Mezil, Antonio M. Caravaca-Aguirre, Edward Z. Zhang, Philippe Moreau, Irène Wang, Paul C. Beard, Emmanuel Bossy
Publicado en: Biomedical Optics Express, Edición 11/10, 2020, Página(s) 5717, ISSN 2156-7085
Editor: The Optical Society
DOI: 10.1364/boe.400686

Numerical model of light propagation through Fabry-Perot etalons composed of interfaces with non-planar surface topography

Autores: Dylan M. Marques, James A. Guggenheim, Peter R. T. Munro
Publicado en: Optics Express, Edición 30, 2024, Página(s) 46294, ISSN 1094-4087
Editor: Optical Society of America
DOI: 10.1364/oe.472308

Spatially resolved readout of a Fabry–Perot ultrasound sensor interrogated through a multimode optical fiber using wavefront shaping

Autores: Benjamin Keenlyside, Dylan Marques, Nathaniel Redgewell, Maxim Cherkashin, Edward Zhang, Paul Beard, James Guggenheim
Publicado en: Applied Physics Letters, Edición 123, 2025, ISSN 0003-6951
Editor: American Institute of Physics
DOI: 10.1063/5.0166826

Analysing the impact of non-parallelism in Fabry-Perot etalons through optical modelling

Autores: Dylan M. Marques, James A. Guggenheim, Peter R. T. Munro
Publicado en: Optics Express, Edición 29, 2024, Página(s) 21603, ISSN 1094-4087
Editor: Optical Society of America
DOI: 10.1364/oe.425487

Use of a flexible optical fibre bundle to interrogate a Fabry–Perot sensor for photoacoustic imaging

Autores: Rehman Ansari, Edward Z. Zhang, Adrien E. Desjardins, Anna L. David, Paul C. Beard
Publicado en: Optics Express, Edición 27/26, 2019, Página(s) 37886, ISSN 1094-4087
Editor: Optical Society of America
DOI: 10.1364/oe.27.037886

Towards clinical application of freehand optical ultrasound imaging

Autores: Fraser T. Watt, Eleanor C. Mackle, Edward Z. Zhang, Paul C. Beard, Erwin J. Alles
Publicado en: Scientific Reports, Edición 14, 2024, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-024-69826-1

The visible and near-infrared optical absorption coefficient spectrum of Parylene C measured by transmitting light through thin films in liquid filled cuvettes

Autores: James A. Guggenheim, Yuanyuan Lyu, Dylan M. Marques, Edward Z. Zhang, Paul C. Beard
Publicado en: Optical Materials Express, Edición 11, 2024, Página(s) 3854, ISSN 2159-3930
Editor: Optical Society of America
DOI: 10.1364/ome.427952

Modelling Fabry-Pérot etalons illuminated by focussed beams

Autores: Dylan M. Marques, James A. Guggenheim, Rehman Ansari, Edward Z. Zhang, Paul C. Beard, Peter R. T. Munro
Publicado en: Optics Express, Edición 28/5, 2020, Página(s) 7691, ISSN 1094-4087
Editor: Optical Society of America
DOI: 10.1364/oe.382526

Estimating blood oxygenation from photoacoustic images: can a simple linear spectroscopic inversion ever work?

Autores: Roman Hochuli, Lu An, Paul C. Beard, Benjamin T. Cox
Publicado en: Journal of Biomedical Optics, Edición 24/12, 2019, Página(s) 1, ISSN 1083-3668
Editor: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.24.12.121914

High pulse energy fibre laser as an excitation source for photoacoustic tomography

Autores: Thomas J. Allen, Martin Berendt, Di Lin, Shaiful U. Alam, Nam T. Huynh, Edward Zhang, David J. Richardson, Paul C. Beard
Publicado en: Optics Express, Edición 28, 2024, Página(s) 34255, ISSN 1094-4087
Editor: Optical Society of America
DOI: 10.1364/oe.401708

Single-pixel camera photoacoustic tomography

Autores: Nam Huynh, Felix Lucka, Edward Zhang, Marta Betcke, Simon R. Arridge, Paul C. Beard, Benjamin T. Cox
Publicado en: Journal of Biomedical Optics, Edición 24/12, 2019, Página(s) 1, ISSN 1083-3668
Editor: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.24.12.121907

Dual-modality rigid endoscope for photoacoustic imaging and white light videoscopy

Autores: Rehman Ansari, Edward Zhang, Paul Beard
Publicado en: Journal of Biomedical Optics, Edición 29, 2024, ISSN 1083-3668
Editor: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.29.2.020502

ABCD transfer matrix model of Gaussian beam propagation in plano-concave optical microresonators

Autores: David Martin-Sanchez, Jing Li, Edward Z. Zhang, Paul C. Beard, James A. Guggenheim
Publicado en: Optics Express, Edición 31, 2024, Página(s) 16523, ISSN 1094-4087
Editor: Optical Society of America
DOI: 10.1364/oe.484212

All-optical forward-viewing photoacoustic probe for high-resolution 3D endoscopy

Autores: Rehman Ansari, Edward Z. Zhang, Adrien E. Desjardins, Paul C. Beard
Publicado en: Light: Science & Applications, Edición 7/1, 2018, ISSN 2047-7538
Editor: Nature
DOI: 10.1038/s41377-018-0070-5

All-optical dual photoacoustic and optical coherence tomography intravascular probe

Autores: Sunish J. Mathews, Callum Little, Christopher D. Loder, Roby D. Rakhit, Wenfeng Xia, Edward Z. Zhang, Paul C. Beard, Malcolm C. Finlay, Adrien E. Desjardins
Publicado en: Photoacoustics, Edición 11, 2018, Página(s) 65-70, ISSN 2213-5979
Editor: Elsevier GmbH
DOI: 10.1016/j.pacs.2018.07.002

All-Optical Rotational Ultrasound Imaging

Autores: Richard J. Colchester, Callum Little, George Dwyer, Sacha Noimark, Erwin J. Alles, Edward Z. Zhang, Christopher D. Loder, Ivan P. Parkin, Ioannis Papakonstantinou, Paul C. Beard, Malcolm C. Finlay, Roby D. Rakhit, Adrien E. Desjardins
Publicado en: Scientific Reports, Edición 9/1, 2019, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-019-41970-z

Reverberant cavity photoacoustic imaging

Autores: M. D. Brown, E. Z. Zhang, B. E. Treeby, P. C. Beard, B. T. Cox
Publicado en: Optica, Edición 6/6, 2019, Página(s) 821, ISSN 2334-2536
Editor: OSA
DOI: 10.1364/optica.6.000821

Monitoring neovascularization and integration of decellularized human scaffolds using photoacoustic imaging

Autores: Olumide Ogunlade, Jasmine O.Y. Ho, Tammy L. Kalber, Robert E. Hynds, Edward Zhang, Sam M. Janes, Martin A. Birchall, Colin R. Butler, Paul Beard
Publicado en: Photoacoustics, Edición 13, 2019, Página(s) 76-84, ISSN 2213-5979
Editor: Elsevier GmbH
DOI: 10.1016/j.pacs.2019.01.001

Non-iterative model-based inversion for low channel-count optical ultrasound imaging

Autores: Fraser T. Watt, Andreas Hauptmann, Eleanor C. Mackle, Edward Z. Zhang, Paul C. Beard, Erwin J. Alles
Publicado en: The Journal of the Acoustical Society of America, Edición 156, 2025, Página(s) 3514-3522, ISSN 0001-4966
Editor: Acoustical Society of America
DOI: 10.1121/10.0034450

Angular Airy function: a model of Fabry-Perot etalons illuminated by arbitrary beams

Autores: Dylan M. Marques, James A. Guggenheim, Peter R. T. Munro
Publicado en: Optics Express, Edición 29, 2024, Página(s) 24144, ISSN 1094-4087
Editor: Optical Society of America
DOI: 10.1364/oe.431362

Sensitive broadband ultrasound sensor based on a low-loss high-Q fused-silica plano-concave microresonator

Autores: David Martín-Sánchez, Edward Z. Zhang, Zhixin Liu, James A. Guggenheim, Paul C. Beard
Publicado en: Optics Express, Edición 33, 2025, Página(s) 39875, ISSN 1094-4087
Editor: Optical Society of America
DOI: 10.1364/oe.572433

An optical coherence photoacoustic microscopy system using a fiber optic sensor

Autores: Shiyu Deng, Richard Haindl, Edward Zhang, Paul Beard, Eva Scheuringer, Caterina Sturtzel, Qian Li, Abigail J. Deloria, Harald Sattmann, Rainer A. Leitgeb, Yi Yuan, Leopold Schmetterer, Manojit Pramanik, Martin Distel, Wolfgang Drexler, Mengyang Liu
Publicado en: APL Photonics, Edición 6, 2025, ISSN 2378-0967
Editor: AIP Publishing
DOI: 10.1063/5.0059351

Laser frequency noise characterization using high-finesse plano–concave optical microresonators

Autores: David Martin-Sanchez, Edward Z. Zhang, Jake Paterson, James A. Guggenheim, Zhixin Liu, Paul C. Beard
Publicado en: Optics Letters, Edición 49, 2024, Página(s) 678, ISSN 0146-9592
Editor: Optical Society of America
DOI: 10.1364/ol.510516

Longitudinal Photoacoustic Imaging of the Pharmacodynamic Effect of Vascular Targeted Therapy on Tumors

Autores: S. Peter Johnson, Olumide Ogunlade, Mark F. Lythgoe, Paul Beard, R. Barbara Pedley
Publicado en: Clinical Cancer Research, Edición 25/24, 2019, Página(s) 7436-7447, ISSN 1078-0432
Editor: American Association for Cancer Research
DOI: 10.1158/1078-0432.ccr-19-0360

Photoacoustic imaging of the human placental vasculature

Autores: Efthymios Maneas, Rosalind Aughwane, Nam Huynh, Wenfeng Xia, Rehman Ansari, Mithun Kuniyil Ajith Singh, J. Ciaran Hutchinson, Neil J. Sebire, Owen J. Arthurs, Jan Deprest, Sebastien Ourselin, Paul C. Beard, Andrew Melbourne, Tom Vercauteren, Anna L. David, Adrien E. Desjardins
Publicado en: Journal of Biophotonics, Edición 13/4, 2020, ISSN 1864-063X
Editor: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/jbio.201900167

Holographic diffusers for endoluminal-scale optical ultrasound imaging

Autores: Fraser T. Watt, Efthymios Maneas, Desta Chan, Edward Z. Zhang, Paul C. Beard, Erwin J. Alles
Publicado en: Journal of Biomedical Optics, Edición 31, 2026, ISSN 1083-3668
Editor: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.31.1.016006

Conference proceedings (3)

Real-Time, Video-Rate and Depth-Resolved Imaging of Radio-Frequency Ablation Using All-Optical Ultrasound

Autores: Erwin J Alles, Richard J Colchester, Yousuf Makki, Sacha Noimark, Edward Z Zhang, Paul C Beard, Malcolm C Finlay, Adrien E Desjardins
Publicado en: 2018 IEEE International Ultrasonics Symposium (IUS), 2020, Página(s) 1-9
Editor: IEEE
DOI: 10.1109/ultsym.2018.8580211

Dual-Modality All-Optical Ultrasound and Photoacoustic Imaging Using Permanent Marker Ink

Autores: Richard J Colchester, Sacha Noimark, Edward Z Zhang, Paul C Beard, Adrien E Desjardins
Publicado en: 2018 IEEE International Ultrasonics Symposium (IUS), 2020, Página(s) 1-4
Editor: IEEE
DOI: 10.1109/ultsym.2018.8579904

Reconfigurable 1.5D Source Arrays for Improved Elevational Focussing in All-Optical Ultrasound Imaging

Autores: Erwin J Alles, Sacha Noimark, Efthymia Papaevangelou, Edward Z Zhang, Paul C Beard, Adrien E Dcsjardins
Publicado en: 2018 IEEE International Ultrasonics Symposium (IUS), 2020, Página(s) 1-9
Editor: IEEE
DOI: 10.1109/ultsym.2018.8580210

Non-peer reviewed articles (1)

Broadband All-Optical Plane-Wave Ultrasound Imaging System Based on a Fabry–Perot Scanner

Autores: Khoa Pham, Sacha Noimark, Nam Huynh, Edward Zhang, Filip Kuklis, Jiri Jaros, Adrien Desjardins, Ben Cox, Paul Beard
Publicado en: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Edición 68, 2022, Página(s) 1007-1016, ISSN 0885-3010
Editor: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tuffc.2020.3028749