Advanced clinical photoacoustic imaging systems based on optical microresonator detection

Informazioni relative al progetto

Photoclin

ID dell’accordo di sovvenzione: 741149

DOI

10.3030/741149

Progetto chiuso

Data della firma CE 21 Agosto 2017

Data di avvio 1 Dicembre 2017

Data di completamento 30 Aprile 2025

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 2 163 061,00

Contributo UE

€ 2 163 061,00

Coordinato da

UNIVERSITY COLLEGE LONDON
United Kingdom

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (33)

A fast all-optical 3D photoacoustic scanner for clinical vascular imaging

Autori: N. T. Huynh, E. Zhang, O. Francies, F. Kuklis, T. Allen, J. Zhu, O. Abeyakoon, F. Lucka, M. Betcke, J. Jaros, S. Arridge, B. Cox, A. A. Plumb, P. Beard
Pubblicato in: Nature Biomedical Engineering, Numero 9, 2025, Pagina/e 638-655, ISSN 2157-846X
Editore: Springer Science and Business Media LLC
DOI: 10.1038/s41551-024-01247-x

Multimodal optical ultrasound imaging: Real-time imaging under concurrent CT or MRI

Autori: Fraser T. Watt, Vivek Muthurangu, Jennifer Steeden, Eleanor C. Mackle, Adrien E. Desjardins, Edward Z. Zhang, Paul C. Beard, Erwin J. Alles
Pubblicato in: APL Photonics, Numero 9, 2025, ISSN 2378-0967
Editore: AIP Publishing
DOI: 10.1063/5.0225554

Analysis of the Directivity of Glass-Etalon Fabry–Pérot Ultrasound Sensors

Autori: Danny R. Ramasawmy, Eleanor Martin, James A. Guggenheim, Edward Z. Zhang, Paul C. Beard, Bradley E. Treeby, Ben T. Cox
Pubblicato in: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Numero 66/9, 2019, Pagina/e 1504-1513, ISSN 0885-3010
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tuffc.2019.2921735

Sustained real-time and video-rate interventional optical ultrasound imaging

Autori: Robert M. Stafford-Williams, Richard J. Colchester, Semyon Bodian, Seán Cardiff, Efthymios Maneas, Edward Z. Zhang, Paul C. Beard, Manish K. Tiwari, Adrien E. Desjardins, Erwin J. Alles
Pubblicato in: Journal of Biomedical Optics, Numero 30, 2025, ISSN 1083-3668
Editore: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.30.3.036005

Freehand and video-rate all-optical ultrasound imaging

Autori: Erwin J. Alles, Eleanor C. Mackle, Sacha Noimark, Edward Z. Zhang, Paul C. Beard, Adrien E. Desjardins
Pubblicato in: Ultrasonics, Numero 116, 2025, Pagina/e 106514, ISSN 0041-624X
Editore: Elsevier BV
DOI: 10.1016/j.ultras.2021.106514

Mitigating the Limited View Problem in Photoacoustic Tomography for a Planar Detection Geometry by Regularized Iterative Reconstruction

Autori: Jiaqi Zhu, Nam Huynh, Olumide Ogunlade, Rehman Ansari, Felix Lucka, Ben Cox, Paul Beard
Pubblicato in: IEEE Transactions on Medical Imaging, Numero 42, 2023, Pagina/e 2603-2615, ISSN 0278-0062
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tmi.2023.3271390

High-resolution imaging of ultrasonic fields through a multimode optical fiber

Autori: Benjamin Keenlyside, Dylan Marques, David B. Phillips, Edward Zhang, Paul Beard, James Guggenheim
Pubblicato in: Physical Review Applied, Numero 24, 2025, ISSN 2331-7019
Editore: American Physical Society (APS)
DOI: 10.1103/nrzh-hqsh

Single-shot hybrid photoacoustic-fluorescent microendoscopy through a multimode fiber with wavefront shaping

Autori: Sylvain Mezil, Antonio M. Caravaca-Aguirre, Edward Z. Zhang, Philippe Moreau, Irène Wang, Paul C. Beard, Emmanuel Bossy
Pubblicato in: Biomedical Optics Express, Numero 11/10, 2020, Pagina/e 5717, ISSN 2156-7085
Editore: The Optical Society
DOI: 10.1364/boe.400686

Numerical model of light propagation through Fabry-Perot etalons composed of interfaces with non-planar surface topography

Autori: Dylan M. Marques, James A. Guggenheim, Peter R. T. Munro
Pubblicato in: Optics Express, Numero 30, 2024, Pagina/e 46294, ISSN 1094-4087
Editore: Optical Society of America
DOI: 10.1364/oe.472308

Spatially resolved readout of a Fabry–Perot ultrasound sensor interrogated through a multimode optical fiber using wavefront shaping

Autori: Benjamin Keenlyside, Dylan Marques, Nathaniel Redgewell, Maxim Cherkashin, Edward Zhang, Paul Beard, James Guggenheim
Pubblicato in: Applied Physics Letters, Numero 123, 2025, ISSN 0003-6951
Editore: American Institute of Physics
DOI: 10.1063/5.0166826

Analysing the impact of non-parallelism in Fabry-Perot etalons through optical modelling

Autori: Dylan M. Marques, James A. Guggenheim, Peter R. T. Munro
Pubblicato in: Optics Express, Numero 29, 2024, Pagina/e 21603, ISSN 1094-4087
Editore: Optical Society of America
DOI: 10.1364/oe.425487

Use of a flexible optical fibre bundle to interrogate a Fabry–Perot sensor for photoacoustic imaging

Autori: Rehman Ansari, Edward Z. Zhang, Adrien E. Desjardins, Anna L. David, Paul C. Beard
Pubblicato in: Optics Express, Numero 27/26, 2019, Pagina/e 37886, ISSN 1094-4087
Editore: Optical Society of America
DOI: 10.1364/oe.27.037886

Towards clinical application of freehand optical ultrasound imaging

Autori: Fraser T. Watt, Eleanor C. Mackle, Edward Z. Zhang, Paul C. Beard, Erwin J. Alles
Pubblicato in: Scientific Reports, Numero 14, 2024, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-024-69826-1

The visible and near-infrared optical absorption coefficient spectrum of Parylene C measured by transmitting light through thin films in liquid filled cuvettes

Autori: James A. Guggenheim, Yuanyuan Lyu, Dylan M. Marques, Edward Z. Zhang, Paul C. Beard
Pubblicato in: Optical Materials Express, Numero 11, 2024, Pagina/e 3854, ISSN 2159-3930
Editore: Optical Society of America
DOI: 10.1364/ome.427952

Modelling Fabry-Pérot etalons illuminated by focussed beams

Autori: Dylan M. Marques, James A. Guggenheim, Rehman Ansari, Edward Z. Zhang, Paul C. Beard, Peter R. T. Munro
Pubblicato in: Optics Express, Numero 28/5, 2020, Pagina/e 7691, ISSN 1094-4087
Editore: Optical Society of America
DOI: 10.1364/oe.382526

Estimating blood oxygenation from photoacoustic images: can a simple linear spectroscopic inversion ever work?

Autori: Roman Hochuli, Lu An, Paul C. Beard, Benjamin T. Cox
Pubblicato in: Journal of Biomedical Optics, Numero 24/12, 2019, Pagina/e 1, ISSN 1083-3668
Editore: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.24.12.121914

High pulse energy fibre laser as an excitation source for photoacoustic tomography

Autori: Thomas J. Allen, Martin Berendt, Di Lin, Shaiful U. Alam, Nam T. Huynh, Edward Zhang, David J. Richardson, Paul C. Beard
Pubblicato in: Optics Express, Numero 28, 2024, Pagina/e 34255, ISSN 1094-4087
Editore: Optical Society of America
DOI: 10.1364/oe.401708

Single-pixel camera photoacoustic tomography

Autori: Nam Huynh, Felix Lucka, Edward Zhang, Marta Betcke, Simon R. Arridge, Paul C. Beard, Benjamin T. Cox
Pubblicato in: Journal of Biomedical Optics, Numero 24/12, 2019, Pagina/e 1, ISSN 1083-3668
Editore: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.24.12.121907

Dual-modality rigid endoscope for photoacoustic imaging and white light videoscopy

Autori: Rehman Ansari, Edward Zhang, Paul Beard
Pubblicato in: Journal of Biomedical Optics, Numero 29, 2024, ISSN 1083-3668
Editore: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.29.2.020502

ABCD transfer matrix model of Gaussian beam propagation in plano-concave optical microresonators

Autori: David Martin-Sanchez, Jing Li, Edward Z. Zhang, Paul C. Beard, James A. Guggenheim
Pubblicato in: Optics Express, Numero 31, 2024, Pagina/e 16523, ISSN 1094-4087
Editore: Optical Society of America
DOI: 10.1364/oe.484212

All-optical forward-viewing photoacoustic probe for high-resolution 3D endoscopy

Autori: Rehman Ansari, Edward Z. Zhang, Adrien E. Desjardins, Paul C. Beard
Pubblicato in: Light: Science & Applications, Numero 7/1, 2018, ISSN 2047-7538
Editore: Nature
DOI: 10.1038/s41377-018-0070-5

All-optical dual photoacoustic and optical coherence tomography intravascular probe

Autori: Sunish J. Mathews, Callum Little, Christopher D. Loder, Roby D. Rakhit, Wenfeng Xia, Edward Z. Zhang, Paul C. Beard, Malcolm C. Finlay, Adrien E. Desjardins
Pubblicato in: Photoacoustics, Numero 11, 2018, Pagina/e 65-70, ISSN 2213-5979
Editore: Elsevier GmbH
DOI: 10.1016/j.pacs.2018.07.002

All-Optical Rotational Ultrasound Imaging

Autori: Richard J. Colchester, Callum Little, George Dwyer, Sacha Noimark, Erwin J. Alles, Edward Z. Zhang, Christopher D. Loder, Ivan P. Parkin, Ioannis Papakonstantinou, Paul C. Beard, Malcolm C. Finlay, Roby D. Rakhit, Adrien E. Desjardins
Pubblicato in: Scientific Reports, Numero 9/1, 2019, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-019-41970-z

Reverberant cavity photoacoustic imaging

Autori: M. D. Brown, E. Z. Zhang, B. E. Treeby, P. C. Beard, B. T. Cox
Pubblicato in: Optica, Numero 6/6, 2019, Pagina/e 821, ISSN 2334-2536
Editore: OSA
DOI: 10.1364/optica.6.000821

Monitoring neovascularization and integration of decellularized human scaffolds using photoacoustic imaging

Autori: Olumide Ogunlade, Jasmine O.Y. Ho, Tammy L. Kalber, Robert E. Hynds, Edward Zhang, Sam M. Janes, Martin A. Birchall, Colin R. Butler, Paul Beard
Pubblicato in: Photoacoustics, Numero 13, 2019, Pagina/e 76-84, ISSN 2213-5979
Editore: Elsevier GmbH
DOI: 10.1016/j.pacs.2019.01.001

Non-iterative model-based inversion for low channel-count optical ultrasound imaging

Autori: Fraser T. Watt, Andreas Hauptmann, Eleanor C. Mackle, Edward Z. Zhang, Paul C. Beard, Erwin J. Alles
Pubblicato in: The Journal of the Acoustical Society of America, Numero 156, 2025, Pagina/e 3514-3522, ISSN 0001-4966
Editore: Acoustical Society of America
DOI: 10.1121/10.0034450

Angular Airy function: a model of Fabry-Perot etalons illuminated by arbitrary beams

Autori: Dylan M. Marques, James A. Guggenheim, Peter R. T. Munro
Pubblicato in: Optics Express, Numero 29, 2024, Pagina/e 24144, ISSN 1094-4087
Editore: Optical Society of America
DOI: 10.1364/oe.431362

Sensitive broadband ultrasound sensor based on a low-loss high-Q fused-silica plano-concave microresonator

Autori: David Martín-Sánchez, Edward Z. Zhang, Zhixin Liu, James A. Guggenheim, Paul C. Beard
Pubblicato in: Optics Express, Numero 33, 2025, Pagina/e 39875, ISSN 1094-4087
Editore: Optical Society of America
DOI: 10.1364/oe.572433

An optical coherence photoacoustic microscopy system using a fiber optic sensor

Autori: Shiyu Deng, Richard Haindl, Edward Zhang, Paul Beard, Eva Scheuringer, Caterina Sturtzel, Qian Li, Abigail J. Deloria, Harald Sattmann, Rainer A. Leitgeb, Yi Yuan, Leopold Schmetterer, Manojit Pramanik, Martin Distel, Wolfgang Drexler, Mengyang Liu
Pubblicato in: APL Photonics, Numero 6, 2025, ISSN 2378-0967
Editore: AIP Publishing
DOI: 10.1063/5.0059351

Laser frequency noise characterization using high-finesse plano–concave optical microresonators

Autori: David Martin-Sanchez, Edward Z. Zhang, Jake Paterson, James A. Guggenheim, Zhixin Liu, Paul C. Beard
Pubblicato in: Optics Letters, Numero 49, 2024, Pagina/e 678, ISSN 0146-9592
Editore: Optical Society of America
DOI: 10.1364/ol.510516

Longitudinal Photoacoustic Imaging of the Pharmacodynamic Effect of Vascular Targeted Therapy on Tumors

Autori: S. Peter Johnson, Olumide Ogunlade, Mark F. Lythgoe, Paul Beard, R. Barbara Pedley
Pubblicato in: Clinical Cancer Research, Numero 25/24, 2019, Pagina/e 7436-7447, ISSN 1078-0432
Editore: American Association for Cancer Research
DOI: 10.1158/1078-0432.ccr-19-0360

Photoacoustic imaging of the human placental vasculature

Autori: Efthymios Maneas, Rosalind Aughwane, Nam Huynh, Wenfeng Xia, Rehman Ansari, Mithun Kuniyil Ajith Singh, J. Ciaran Hutchinson, Neil J. Sebire, Owen J. Arthurs, Jan Deprest, Sebastien Ourselin, Paul C. Beard, Andrew Melbourne, Tom Vercauteren, Anna L. David, Adrien E. Desjardins
Pubblicato in: Journal of Biophotonics, Numero 13/4, 2020, ISSN 1864-063X
Editore: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/jbio.201900167

Holographic diffusers for endoluminal-scale optical ultrasound imaging

Autori: Fraser T. Watt, Efthymios Maneas, Desta Chan, Edward Z. Zhang, Paul C. Beard, Erwin J. Alles
Pubblicato in: Journal of Biomedical Optics, Numero 31, 2026, ISSN 1083-3668
Editore: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.31.1.016006

Conference proceedings (3)

Real-Time, Video-Rate and Depth-Resolved Imaging of Radio-Frequency Ablation Using All-Optical Ultrasound

Autori: Erwin J Alles, Richard J Colchester, Yousuf Makki, Sacha Noimark, Edward Z Zhang, Paul C Beard, Malcolm C Finlay, Adrien E Desjardins
Pubblicato in: 2018 IEEE International Ultrasonics Symposium (IUS), 2020, Pagina/e 1-9
Editore: IEEE
DOI: 10.1109/ultsym.2018.8580211

Dual-Modality All-Optical Ultrasound and Photoacoustic Imaging Using Permanent Marker Ink

Autori: Richard J Colchester, Sacha Noimark, Edward Z Zhang, Paul C Beard, Adrien E Desjardins
Pubblicato in: 2018 IEEE International Ultrasonics Symposium (IUS), 2020, Pagina/e 1-4
Editore: IEEE
DOI: 10.1109/ultsym.2018.8579904

Reconfigurable 1.5D Source Arrays for Improved Elevational Focussing in All-Optical Ultrasound Imaging

Autori: Erwin J Alles, Sacha Noimark, Efthymia Papaevangelou, Edward Z Zhang, Paul C Beard, Adrien E Dcsjardins
Pubblicato in: 2018 IEEE International Ultrasonics Symposium (IUS), 2020, Pagina/e 1-9
Editore: IEEE
DOI: 10.1109/ultsym.2018.8580210

Non-peer reviewed articles (1)

Broadband All-Optical Plane-Wave Ultrasound Imaging System Based on a Fabry–Perot Scanner

Autori: Khoa Pham, Sacha Noimark, Nam Huynh, Edward Zhang, Filip Kuklis, Jiri Jaros, Adrien Desjardins, Ben Cox, Paul Beard
Pubblicato in: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Numero 68, 2022, Pagina/e 1007-1016, ISSN 0885-3010
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tuffc.2020.3028749