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Developing Geroprotectors to Prevent Polymorbidity

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Longevity in response to lowered insulin signaling requires glycine N‐methyltransferase‐dependent spermidine production

Author(s): Luke S. Tain, Chirag Jain, Tobias Nespital, Jenny Froehlich, Yvonne Hinze, Sebastian Grönke, Linda Partridge
Published in: Aging Cell, 19/1, 2019, ISSN 1474-9718
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/acel.13043

A triple drug combination targeting components of the nutrient-sensing network maximizes longevity

Author(s): Jorge Iván Castillo-Quan, Luke S. Tain, Kerri J. Kinghorn, Li Li, Sebastian Grönke, Yvonne Hinze, T. Keith Blackwell, Ivana Bjedov, Linda Partridge
Published in: Proceedings of the National Academy of Sciences, 116/42, 2019, Page(s) 20817-20819, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1913212116

Horizons in the evolution of aging

Author(s): Thomas Flatt, Linda Partridge
Published in: BMC Biology, 16/1, 2018, ISSN 1741-7007
Publisher: BioMed Central
DOI: 10.1186/s12915-018-0562-z

The quest to slow ageing through drug discovery

Author(s): Linda Partridge, Matias Fuentealba, Brian K. Kennedy
Published in: Nature Reviews Drug Discovery, 2020, ISSN 1474-1776
Publisher: Nature Publishing Group
DOI: 10.1038/s41573-020-0067-7

Facing up to the global challenges of ageing

Author(s): Linda Partridge, Joris Deelen, P. Eline Slagboom
Published in: Nature, 561/7721, 2018, Page(s) 45-56, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-018-0457-8