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PRECISION CARE IN SYSTEMIC AUTOIMMUNITY: AN INTEGRATED MULTI-TISSUE/LEVEL APPROACH FOR SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

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Publications

Lupus or not? SLE Risk Probability Index (SLERPI): a simple, clinician-friendly machine learning-based model to assist the diagnosis of systemic lupus erythematosus

Author(s): Christina Adamichou, Irini Genitsaridi, Dionysis Nikolopoulos, Myrto Nikoloudaki, Argyro Repa, Alessandra Bortoluzzi, Antonis Fanouriakis, Prodromos Sidiropoulos, Dimitrios T Boumpas, George K Bertsias
Published in: Annals of the Rheumatic Diseases, 2021, Page(s) annrheumdis-2020-219069, ISSN 0003-4967
Publisher: BMJ Publishing Group
DOI: 10.1136/annrheumdis-2020-219069

Fabrication of a 3D microfluidic cell culture device for bone marrow-on-a-chip

Author(s): Dionysia Kefallinou, Maria Grigoriou, Dimitrios T. Boumpas, Evangelos Gogolides, Angeliki Tserepi
Published in: Micro and Nano Engineering, 9, 2020, Page(s) 100075, ISSN 2590-0072
Publisher: ELSEVIER
DOI: 10.1016/j.mne.2020.100075

Sexual dimorphism in SLE: above and beyond sex hormones

Author(s): E.A.A. Christou, A. Banos, D. Kosmara, GK Bertsias, DT Boumpas
Published in: Lupus, 28/1, 2018, Page(s) 3-10, ISSN 0961-2033
Publisher: SAGE Publications
DOI: 10.1177/0961203318815768

REDD1/autophagy pathway promotes thromboinflammation and fibrosis in human systemic lupus erythematosus (SLE) through NETs decorated with tissue factor (TF) and interleukin-17A (IL-17A)

Author(s): Eleni Frangou, Akrivi Chrysanthopoulou, Alexandros Mitsios, Konstantinos Kambas, Stella Arelaki, Iliana Angelidou, Athanasios Arampatzioglou, Hariklia Gakiopoulou, George K Bertsias, Panayotis Verginis, Konstantinos Ritis, Dimitrios T Boumpas
Published in: Annals of the Rheumatic Diseases, 2018, Page(s) annrheumdis-2018-213181, ISSN 0003-4967
Publisher: BMJ Publishing Group
DOI: 10.1136/annrheumdis-2018-213181

IFNα Impairs Autophagic Degradation of mtDNA Promoting Autoreactivity of SLE Monocytes in a STING-Dependent Fashion

Author(s): Katerina Gkirtzimanaki, Eleni Kabrani, Dimitra Nikoleri, Alexander Polyzos, Athanasios Blanas, Prodromos Sidiropoulos, Antonis Makrigiannakis, George Bertsias, Dimitrios T. Boumpas, Panayotis Verginis
Published in: Cell Reports, 25/4, 2018, Page(s) 921-933.e5, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2018.09.001

Transcriptome reprogramming and myeloid skewing in haematopoietic stem and progenitor cells in systemic lupus erythematosus

Author(s): Maria Grigoriou, Aggelos Banos, Anastasia Filia, Pavlos Pavlidis, Stavroula Giannouli, Vassiliki Karali, Dionysis Nikolopoulos, Antigone Pieta, George Bertsias, Panayotis Verginis, Ioannis Mitroulis, Dimitrios T Boumpas
Published in: Annals of the Rheumatic Diseases, 2019, Page(s) annrheumdis-2019-215782, ISSN 0003-4967
Publisher: BMJ Publishing Group
DOI: 10.1136/annrheumdis-2019-215782

Evolving phenotype of systemic lupus erythematosus in Caucasians: low incidence of lupus nephritis, high burden of neuropsychiatric disease and increased rates of late-onset lupus in the ‘Attikon’ cohort

Author(s): D Nikolopoulos, M Kostopoulou, A Pieta, T Karageorgas, D Tseronis, K Chavatza, S Flouda, P Rapsomaniki, A Banos, E Kremasmenou, V Tzavara, P Katsimbri, A Fanouriakis, D T Boumpas
Published in: Lupus, 2020, Page(s) 096120332090893, ISSN 0961-2033
Publisher: SAGE Publications
DOI: 10.1177/0961203320908932

Combined genetic and transcriptome analysis of patients with SLE: distinct, targetable signatures for susceptibility and severity

Author(s): Nikolaos I Panousis, George K Bertsias, Halit Ongen, Irini Gergianaki, Maria G Tektonidou, Maria Trachana, Luciana Romano-Palumbo, Deborah Bielser, Cedric Howald, Cristina Pamfil, Antonis Fanouriakis, Despoina Kosmara, Argyro Repa, Prodromos Sidiropoulos, Emmanouil T Dermitzakis, Dimitrios T Boumpas
Published in: Annals of the Rheumatic Diseases, 78/8, 2019, Page(s) 1079-1089, ISSN 0003-4967
Publisher: BMJ Publishing Group
DOI: 10.1136/annrheumdis-2018-214379

Mitochondrial Oxidative Damage Underlies Regulatory T Cell Defects in Autoimmunity

Author(s): Themis Alissafi, Lydia Kalafati, Maria Lazari, Anastasia Filia, Ismini Kloukina, Maria Manifava, Jong-Hyung Lim, Vasileia Ismini Alexaki, Nicholas T. Ktistakis, Triantafyllos Doskas, George A. Garinis, Triantafyllos Chavakis, Dimitrios T. Boumpas, Panayotis Verginis
Published in: Cell Metabolism, Online ahead of print, 2020, Page(s) Online ahead of print, ISSN 1550-4131
Publisher: Cell Press
DOI: 10.1016/j.cmet.2020.07.001

Quality indicators for systemic lupus erythematosus based on the 2019 EULAR recommendations: development and initial validation in a cohort of 220 patients

Author(s): Katerina Chavatza, Myrto Kostopoulou, Dionysis Nikolopoulos, Ourania Gioti, Konstantina Togia, Laura Andreoli, Martin Aringer, John Boletis, Andrea Doria, Frederic A Houssiau, David Jayne, Marta Mosca, Elisabet Svenungsson , Angela Tincani, George Bertsias, Antonis Fanouriakis, Dimitrios T Boumpas
Published in: Annals Rheumatic Disease, 2021, ISSN 0003-4967
Publisher: BMJ Publishing Group
DOI: 10.1136/annrheumdis-2021-220438

NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE

Author(s): Spiros Georgakis, Katerina Gkirtzimanaki, Garyfalia Papadaki, Hariklia Gakiopoulou, Elias Drakos, Maija-Leena Eloranta, Manousos Makridakis, Georgia Kontostathi, Jerome Zoidakis, Eirini Baira, Lars Rönnblom, Dimitrios T. Boumpas, Prodromos Sidiropoulos, Panayotis Verginis, and George Bertsias
Published in: JCI insight, 2021;6(21):e147671, 2021, ISSN 2379-3708
Publisher: American Society for Clinical Investigation
DOI: 10.1172/jci.insight.147671

RNA-sequencing and transcriptome analysis of hematopoietic stem cells in systemic lupus erythematosus

Author(s): Grigoriou Maria
Published in: 2019
Publisher: Medical School of Athens