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Understanding cancer development in BRCA 1/2 mutation carriers for improved Early detection and Risk Control


Non-Surgical Cancer Risk Reduction in BRCA1 Mutation Carriers: Disabling the Remote Control

Author(s): Martin Widschwendter, Louis Dubeau
Published in: Cancers, Issue 12/3, 2020, Page(s) 547, ISSN 2072-6694
DOI: 10.3390/cancers12030547

DNA Methylation Patterns in Normal Tissue Correlate more Strongly with Breast Cancer Status than Copy-Number Variants

Author(s): Yang Gao, Martin Widschwendter, Andrew E. Teschendorff
Published in: EBioMedicine, Issue 31, 2018, Page(s) 243-252, ISSN 2352-3964
DOI: 10.1016/j.ebiom.2018.04.025

Do cancer risk and benefit–harm ratios influence women’s consideration of risk-reducing mastectomy? A scenario-based experiment in five European countries

Author(s): Felix G. Rebitschek, Nora Pashayan, Martin Widschwendter, Odette Wegwarth
Published in: PLOS ONE, Issue 14/6, 2019, Page(s) e0218188, ISSN 1932-6203
DOI: 10.1371/journal.pone.0218188

Prognostic gene expression signature for high-grade serous ovarian cancer

Author(s): J. Millstein, T. Budden, E.L. Goode, M.S. Anglesio, A. Talhouk, M.P. Intermaggio, H.S. Leong, S. Chen, W. Elatre, B. Gilks, T. Nazeran, M. Volchek, R.C. Bentley, C. Wang, D.S. Chiu, S. Kommoss, S.C.Y. Leung, J. Senz, A. Lum, V. Chow, H. Sudderuddin, R. Mackenzie, J. George, S. Fereday, J. Hendley, N. Traficante, H. Steed, J.M. Koziak, M. Köbel, I.A. McNeish, T. Goranova, D. Ennis, G. Macintyre, D
Published in: Annals of Oncology, 2020, ISSN 0923-7534
DOI: 10.1016/j.annonc.2020.05.019

Epigenome-based cancer risk prediction: rationale, opportunities and challenges

Author(s): Martin Widschwendter, Allison Jones, Iona Evans, Daniel Reisel, Joakim Dillner, Karin Sundström, Ewout W. Steyerberg, Yvonne Vergouwe, Odette Wegwarth, Felix G. Rebitschek, Uwe Siebert, Gaby Sroczynski, Inez D. de Beaufort, Ineke Bolt, David Cibula, Michal Zikan, Line Bjørge, Nicoletta Colombo, Nadia Harbeck, Frank Dudbridge, Anne-Marie Tasse, Bartha M. Knoppers, Yann Joly, Andrew E. Teschendorf
Published in: Nature Reviews Clinical Oncology, Issue 15/5, 2018, Page(s) 292-309, ISSN 1759-4774
DOI: 10.1038/nrclinonc.2018.30

Association between the cervicovaginal microbiome, BRCA1 mutation status, and risk of ovarian cancer: a case-control study

Author(s): Nuno R Nené, Daniel Reisel, Andreas Leimbach, Dorella Franchi, Allison Jones, Iona Evans, Susanne Knapp, Andy Ryan, Shohreh Ghazali, John F Timms, Tobias Paprotka, Line Bjørge, Michal Zikan, David Cibula, Nicoletta Colombo, Martin Widschwendter
Published in: The Lancet Oncology, Issue 20/8, 2019, Page(s) 1171-1182, ISSN 1470-2045
DOI: 10.1016/s1470-2045(19)30340-7