Retooling plant immunity for resistance to blast fungi

Informazioni relative al progetto

BLASTOFF

ID dell’accordo di sovvenzione: 743165

DOI

10.3030/743165

Progetto chiuso

Data della firma CE 10 Maggio 2017

Data di avvio 1 Settembre 2017

Data di completamento 31 Agosto 2023

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 2 491 893,00

Contributo UE

€ 2 491 893,00

Coordinato da

THE SAINSBURY LABORATORY
United Kingdom

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (28)

Emerging principles in the design of bioengineered made-to-order plant immune receptors

Autori: Clemence Marchal, Hsuan Pai, Sophien Kamoun, Jiorgos Kourelis
Pubblicato in: Current Opinion in Plant Biology, Numero 70, 2023, Pagina/e 102311, ISSN 1369-5266
Editore: Elsevier BV
DOI: 10.1016/j.pbi.2022.102311

Bioengineering a plant NLR immune receptor with a robust binding interface toward a conserved fungal pathogen effector

Autori: Rafał Zdrzałek, Yuxuan Xi, Thorsten Langner, Adam R. Bentham, Yohann Petit-Houdenot, Juan Carlos De la Concepcion, Adeline Harant, Motoki Shimizu, Vincent Were, Nicholas J. Talbot, Ryohei Terauchi, Sophien Kamoun, Mark J. Banfield
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 121, 2024, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2402872121

A blast fungus zinc-finger fold effector binds to a hydrophobic pocket in host Exo70 proteins to modulate immune recognition in rice

Autori: Juan Carlos De la Concepcion, Koki Fujisaki, Adam R. Bentham, Neftaly Cruz Mireles, Victor Sanchez de Medina Hernandez, Motoki Shimizu, David M. Lawson, Sophien Kamoun, Ryohei Terauchi, Mark J. Banfield
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 119, 2023, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2210559119

A genetically linked pair of NLR immune receptors shows contrasting patterns of evolution

Autori: Motoki Shimizu, Akiko Hirabuchi, Yu Sugihara, Akira Abe, Takumi Takeda, Michie Kobayashi, Yukie Hiraka, Eiko Kanzaki, Kaori Oikawa, Hiromasa Saitoh, Thorsten Langner, Mark J. Banfield, Sophien Kamoun, Ryohei Terauchi
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 119, 2022, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2116896119

Two NLR immune receptors acquired high-affinity binding to a fungal effector through convergent evolution of their integrated domain

Autori: Aleksandra Białas, Thorsten Langner, Adeline Harant, Mauricio P Contreras, Clare EM Stevenson, David M Lawson, Jan Sklenar, Ronny Kellner, Matthew J Moscou, Ryohei Terauchi, Mark J Banfield, Sophien Kamoun
Pubblicato in: eLife, Numero 10, 2023, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.66961

Effector target-guided engineering of an integrated domain expands the disease resistance profile of a rice NLR immune receptor

Autori: Josephine HR Maidment, Motoki Shimizu, Adam R Bentham, Sham Vera, Marina Franceschetti, Apinya Longya, Clare EM Stevenson, Juan Carlos De la Concepcion, Aleksandra Białas, Sophien Kamoun, Ryohei Terauchi, Mark J Banfield
Pubblicato in: eLife, Numero 12, 2023, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.81123

RefPlantNLR is a comprehensive collection of experimentally validated plant disease resistance proteins from the NLR family

Autori: Jiorgos Kourelis, Toshiyuki Sakai, Hiroaki Adachi, Sophien Kamoun
Pubblicato in: PLOS Biology, Numero 19, 2021, Pagina/e e3001124, ISSN 1545-7885
Editore: PLOS
DOI: 10.1371/journal.pbio.3001124

Functional diversification gave rise to allelic specialization in a rice NLR immune receptor pair

Autori: Juan Carlos De la Concepcion, Javier Vega Benjumea, Aleksandra Bialas, Ryohei Terauchi, Sophien Kamoun, Mark J Banfield
Pubblicato in: eLife, Numero 10, 2023, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.71662

NLR receptors in plant immunity: making sense of the alphabet soup

Autori: Mauricio P Contreras, Daniel Lüdke, Hsuan Pai, AmirAli Toghani, Sophien Kamoun
Pubblicato in: EMBO reports, Numero 24, 2023, ISSN 1469-221X
Editore: Nature Publishing Group
DOI: 10.15252/embr.202357495

The rice NLR pair Pikp-1/Pikp-2 initiates cell death through receptor cooperation rather than negative regulation

Autori: Rafał Zdrzałek, Sophien Kamoun, Ryohei Terauchi, Hiromasa Saitoh, Mark J Banfield
Pubblicato in: PLOS ONE, 2024, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1101/2020.06.20.162834

The coming of age of EvoMPMI: evolutionary molecular plant–microbe interactions across multiple timescales

Autori: Jessica L Upson, Erin K Zess, Aleksandra Białas, Chih-hang Wu, Sophien Kamoun
Pubblicato in: Current Opinion in Plant Biology, Numero 44, 2018, Pagina/e 108-116, ISSN 1369-5266
Editore: Elsevier BV
DOI: 10.1016/j.pbi.2018.03.003

Cautionary Notes on Use of the MoT3 Diagnostic Assay for Magnaporthe oryzae Wheat and Rice Blast Isolates

Autori: Dipali Rani Gupta, Claudia Sarai Reyes Avila, Joe Win, Darren M. Soanes, Lauren S. Ryder, Daniel Croll, Pallab Bhattacharjee, Md. Shaid Hossain, Nur Uddin Mahmud, Md. Shabab Mehebub, Musrat Zahan Surovy, Md. Mahbubur Rahman, Nicholas J. Talbot, Sophien Kamoun, M. Tofazzal Islam
Pubblicato in: Phytopathology, Numero 109/4, 2019, Pagina/e 504-508, ISSN 0031-949X
Editore: American Phytopathological Society
DOI: 10.1094/phyto-06-18-0199-le

Uncoiling CNLs: Structure/function approaches to understanding CC domain function in plant NLRs

Autori: Adam R Bentham, Rafał Zdrzałek, Juan Carlos De la Concepcion, Mark J Banfield
Pubblicato in: Plant and Cell Physiology, 2018, ISSN 0032-0781
Editore: Oxford University Press
DOI: 10.1093/pcp/pcy185

Lessons in Effector and NLR Biology of Plant-Microbe Systems

Autori: Aleksandra Białas, Erin K. Zess, Juan Carlos De la Concepcion, Marina Franceschetti, Helen G. Pennington, Kentaro Yoshida, Jessica L. Upson, Emilie Chanclud, Chih-Hang Wu, Thorsten Langner, Abbas Maqbool, Freya A. Varden, Lida Derevnina, Khaoula Belhaj, Koki Fujisaki, Hiromasa Saitoh, Ryohei Terauchi, Mark J. Banfield, Sophien Kamoun
Pubblicato in: Molecular Plant-Microbe Interactions, Numero 31/1, 2018, Pagina/e 34-45, ISSN 0894-0282
Editore: American Phytopathological Society
DOI: 10.1094/mpmi-08-17-0196-fi

Gene duplication and mutation in the emergence of a novel aggressive allele of the AVR-Pik effector in the rice blast fungus

Autori: Apinya Longya, Chaivarakun Chaipanya, Marina Franceschetti, Josephine H.R. Maidment, Mark James Banfield, Chatchawan Jantasuriyarat
Pubblicato in: Molecular Plant-Microbe Interactions, 2019, ISSN 0894-0282
Editore: American Phytopathological Society
DOI: 10.1094/mpmi-09-18-0245-r

CRISPR Crops: Plant Genome Editing Toward Disease Resistance

Autori: Thorsten Langner, Sophien Kamoun, Khaoula Belhaj
Pubblicato in: Annual Review of Phytopathology, Numero 56/1, 2018, Pagina/e 479-512, ISSN 0066-4286
Editore: Annual Reviews, Inc.
DOI: 10.1146/annurev-phyto-080417-050158

Plant health emergencies demand open science: Tackling a cereal killer on the run

Autori: Sophien Kamoun, Nicholas J. Talbot, M. Tofazzal Islam
Pubblicato in: PLOS Biology, Numero 17/6, 2019, Pagina/e e3000302, ISSN 1545-7885
Editore: PLOS
DOI: 10.1371/journal.pbio.3000302

An N-terminal motif in NLR immune receptors is functionally conserved across distantly related plant species

Autori: Hiroaki Adachi, Mauricio P Contreras, Adeline Harant, Chih-hang Wu, Lida Derevnina, Toshiyuki Sakai, Cian Duggan, Eleonora Moratto, Tolga O Bozkurt, Abbas Maqbool, Joe Win, Sophien Kamoun
Pubblicato in: eLife, Numero 8, 2019, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.49956

Protein engineering expands the effector recognition profile of a rice NLR immune receptor

Autori: Juan Carlos De la Concepcion, Marina Franceschetti, Dan MacLean, Ryohei Terauchi, Sophien Kamoun, Mark J Banfield
Pubblicato in: eLife, Numero 8, 2019, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.47713

Overcoming plant blindness in science, education, and society

Autori: Sarah B. Jose, Chih‐Hang Wu, Sophien Kamoun
Pubblicato in: PLANTS, PEOPLE, PLANET, Numero 1/3, 2019, Pagina/e 169-172, ISSN 2572-2611
Editore: New Phytologist
DOI: 10.1002/ppp3.51

NLR singletons, pairs, and networks: evolution, assembly, and regulation of the intracellular immunoreceptor circuitry of plants

Autori: Hiroaki Adachi, Lida Derevnina, Sophien Kamoun
Pubblicato in: Current Opinion in Plant Biology, Numero 50, 2019, Pagina/e 121-131, ISSN 1369-5266
Editore: Elsevier BV
DOI: 10.1016/j.pbi.2019.04.007

Cross-reactivity of a rice NLR immune receptor to distinct effectors from the rice blast pathogen Magnaporthe oryzae provides partial disease resistance

Autori: Freya A. Varden, Hiromasa Saitoh, Kae Yoshino, Marina Franceschetti, Sophien Kamoun, Ryohei Terauchi, Mark J. Banfield
Pubblicato in: Journal of Biological Chemistry, Numero 294/35, 2019, Pagina/e 13006-13016, ISSN 0021-9258
Editore: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/jbc.ra119.007730

A global surveillance system for crop diseases

Autori: M. Carvajal-Yepes, K. Cardwell, A. Nelson, K. A. Garrett, B. Giovani, D. G. O. Saunders, S. Kamoun, J. P. Legg, V. Verdier, J. Lessel, R. A. Neher, R. Day, P. Pardey, M. L. Gullino, A. R. Records, B. Bextine, J. E. Leach, S. Staiger, J. Tohme
Pubblicato in: Science, Numero 364/6447, 2019, Pagina/e 1237-1239, ISSN 0036-8075
Editore: American Association for the Advancement of Science
DOI: 10.1126/science.aaw1572

Pyricularia graminis-tritici is not the correct species name for the wheat blast fungus: response to Ceresini et al . (MPP 20:2)

Autori: Barbara Valent, Mark Farman, Yukio Tosa, Dominik Begerow, Elisabeth Fournier, Pierre Gladieux, M. Tofazzal Islam, Sophien Kamoun, Martin Kemler, Linda M. Kohn, Marc-Henri Lebrun, Jason E. Stajich, Nicholas J. Talbot, Ryohei Terauchi, Didier Tharreau, Ning Zhang
Pubblicato in: Molecular Plant Pathology, Numero 20/2, 2019, Pagina/e 173-179, ISSN 1464-6722
Editore: Blackwell Publishing Inc.
DOI: 10.1111/mpp.12778

Polymorphic residues in rice NLRs expand binding and response to effectors of the blast pathogen

Autori: Juan Carlos De la Concepcion, Marina Franceschetti, Abbas Maqbool, Hiromasa Saitoh, Ryohei Terauchi, Sophien Kamoun, Mark J. Banfield
Pubblicato in: Nature Plants, Numero 4/8, 2018, Pagina/e 576-585, ISSN 2055-0278
Editore: Nature
DOI: 10.1038/s41477-018-0194-x

The Blast Fungus Decoded: Genomes in Flux

Autori: Thorsten Langner, Aleksandra Białas, Sophien Kamoun
Pubblicato in: mBio, Numero 9/2, 2018, Pagina/e e00571-18, ISSN 2150-7511
Editore: ASM
DOI: 10.1128/mbio.00571-18

Allelic compatibility in plant immune receptors facilitates engineering of new effector recognition specificities

Autori: Adam R Bentham, Juan Carlos De la Concepcion, Javier Vega Benjumea, Jiorgos Kourelis, Sally Jones, Melanie Mendel, Jack Stubbs, Clare E M Stevenson, Josephine H R Maidment, Mark Youles, Rafał Zdrzałek, Sophien Kamoun, Mark J Banfield
Pubblicato in: The Plant Cell, Numero 35, 2023, Pagina/e 3809-3827, ISSN 1040-4651
Editore: American Society of Plant Biologists
DOI: 10.1093/plcell/koad204

NLR immune receptor–nanobody fusions confer plant disease resistance

Autori: Jiorgos Kourelis, Clemence Marchal, Andres Posbeyikian, Adeline Harant, Sophien Kamoun
Pubblicato in: Science, Numero 379, 2024, Pagina/e 934-939, ISSN 0036-8075
Editore: American Association for the Advancement of Science
DOI: 10.1126/science.abn4116

Other (5)

The blast pathogen effector AVR-Pik binds and stabilizes rice heavy metal-associated (HMA) proteins to co-opt their function in immunity

Autori: Kaori Oikawa, Koki Fujisaki, Motoki Shimizu, Takumi Takeda, Keiichiro Nemoto, Hiromasa Saitoh, Akiko Hirabuchi, Yukie Hiraka, Naomi Miyaji, Aleksandra Białas, Thorsten Langner, Ronny Kellner, Tolga O Bozkurt, Stella Cesari, Thomas Kroj, Mark J Banfield, Sophien Kamoun, Ryohei Terauchi
Pubblicato in: 2024
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/2020.12.01.406389

Ten things we learned in 2010-2019 (aside from everything else)

Autori: Kamoun, Sophien
Pubblicato in: Numero 1, 2019
Editore: Zenodo
DOI: 10.5281/zenodo.3613856

How to select a PhD lab?

Autori: Kamoun, Sophien
Pubblicato in: Numero 1, 2019
Editore: Zenodo
DOI: 10.5281/zenodo.3531916

Open science to tackle a cereal killer on the run

Autori: Sophien Kamoun; Nicholas J. Talbot; M. Tofazzal Islam
Pubblicato in: Numero 2, 2019
Editore: Zenodo
DOI: 10.5281/zenodo.2582429

Effector target-guided engineering of an integrated domain expands the disease resistance profile of a rice NLR immune receptor

Autori: JHR Maidment, M Shimizu, S Vera, M Franceschetti, A Longya, CEM Stevenson, JC De la Concepcion, A Białas, S Kamoun, R Terauchi, MJ Banfield
Pubblicato in: 2024
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/2022.06.14.496076

Conference proceedings (3)

New effectors from the multihost blast fungus Magnaporthe oryzae target HMA domain containing host proteins

Autori: Yohann Petit; Joe Win; Thorsten Langner; Adeline Harant; Ryohei Terauchi; Mark Banfield; Sophien Kamoun
Pubblicato in: Numero 1, 2019
Editore: Zenodo
DOI: 10.5281/zenodo.3352211

The dark matter of genomics: mini-chromosomes as drivers of host adaptation in the blast fungus

Autori: Thorsten Langner; Luis B. Gomez-Luciano; Adeline Harant; Joe Win; Sophien Kamoun
Pubblicato in: Numero 1, 2019
Editore: Zenodo
DOI: 10.5281/zenodo.3349735

A widely conserved N-terminal motif in the coiled-coil domain of NLR immune receptors is required for activation of hypersensitive cell death

Autori: Hiroaki Adachi; Mauricio Contreras; Adeline Harant; Chih-hang Wu; Lida Derevnina; Toshiyuki Sakai; Cian Duggan; Eleonora Moratto; Tolga O Bozkurt; Abbas Maqbool; Joe Win; Sophien Kamoun
Pubblicato in: Numero 1, 2019
Editore: Zenodo
DOI: 10.5281/zenodo.3349849

Non-peer reviewed articles (1)

Stranger in a strange land: the experiences of immigrant researchers

Autori: Sophien Kamoun, Rosa Lozano-Durán, Luay Nakhleh
Pubblicato in: Genome Biology, Numero 18/1, 2017, ISSN 1474-760X
Editore: BMC
DOI: 10.1186/s13059-017-1370-4