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Comprehensive analysis of yeast expression-fitness functions (EFFs)

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Publications

Determining protein structures using deep mutagenesis

Author(s): Jörn M. Schmiedel, Ben Lehner
Published in: Nature Genetics, Issue 51/7, 2019, Page(s) 1177-1186, ISSN 1061-4036
DOI: 10.1038/s41588-019-0431-x

Empirical mean-noise fitness landscapes reveal the fitness impact of gene expression noise

Author(s): Jörn M. Schmiedel, Lucas B. Carey, Ben Lehner
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
DOI: 10.1038/s41467-019-11116-w

DiMSum: an error model and pipeline for analyzing deep mutational scanning data and diagnosing common experimental pathologies

Author(s): Andre J. Faure, Jörn M. Schmiedel, Pablo Baeza-Centurion, Ben Lehner
Published in: Genome Biology, Issue 21/1, 2020, ISSN 1474-760X
DOI: 10.1186/s13059-020-02091-3