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Safety and efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment in patients affected by amyotrophic lateral sclerosis (ALS)

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Report on status of posting results in the study registry (opens in new window)

Report on status of posting results in the study registry. The report will include the status of the result posting as well as the timelines when final posting of results is scheduled at end of funding period (Month 72)

Dissemination and exploitation plan (opens in new window)

Dissemination and Exploitation Plan. The document will describe the dissemination and exploitation strategies and action plan (Month 3

Statistical analysis of primary and secondary outcome variables (opens in new window)

Statistical analysis of primary and secondary outcome variables. (Month 72) This report will include the statistical analysis on primary and secondaty outcome variables

Demographic and clinical description of the study population (opens in new window)

This report will include study population data on demographic and clinical aspects

Statistical analysis of biomarker and correlation with clinical outcomes (opens in new window)

Statistical analysis of biomarker and correlation with clinical outcomes. (Month 66) This report will include data on statistical analysis of biomarkers and related correlation to clinical outcomes.

Project website (opens in new window)

Project website. The report will include the characteristics of the website, the activities involved for its creation and print screens of the website pages (Month 6

Publications

Review of disease-modifying drug trials in amyotrophic lateral sclerosis (opens in new window)

Author(s): Paolo Tornese; Stefania Lalli; Antoniangela Cocco; Alberto Albanese
Published in: Journal of Neurology Neurosurgery and Psychiatry, Issue 3, 2022, Page(s) 521-529, ISSN 0022-3050
Publisher: BMJ Publishing Group
DOI: 10.1136/jnnp-2021-328470

Tauro-Urso-Deoxycholic Acid Trials in Amyotrophic Lateral Sclerosis: What is Achieved and What to Expect (opens in new window)

Author(s): Maria Lo Giudice, Antoniangela Cocco, Giorgio Reggiardo, Stefania Lalli, Alberto Albanese
Published in: Clinical Drug Investigation, 2023, ISSN 1179-1918
Publisher: Springer
DOI: 10.1007/s40261-023-01324-0

Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases (opens in new window)

Author(s): Kareem Khalaf; Paolo Tornese; Antoniangela Cocco; Alberto Albanese
Published in: Translational Neurodegeneration, Issue 3, 2022, Page(s) 33, ISSN 2047-9158
Publisher: Springer Nature
DOI: 10.1186/s40035-022-00307-z

A randomized double-blind clinical trial on safety and efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment in patients affected by amyotrophic lateral sclerosis (ALS): the statistical analysis plan of TUDCA-ALS trial (opens in new window)

Author(s): Flavia L Lombardo, Stefania Spila Alegiani, Flavia Mayer, Marta Cipriani, Maria Lo Giudice, Albert Christian Ludolph, Christopher J McDermott, Philippe Corcia, Philip Van Damme, Leonard H Van den Berg, Orla Hardiman, Gabriele Nicolini, Nicola Vanacore, Brian Dickie, Alberto Albanese, Maria Puopolo; TUDCA-ALS Study Group (Paolo Tornese, Antoniangela Cocco, Michela Matteoli, Eliana Lauranzano, Maria
Published in: Trials, 2023, ISSN 1745-6215
Publisher: BioMed Central
DOI: 10.1186/s13063-023-07638-w

Cox regression and survival analysis from the tauro-urso-deoxycholic trial in amyotrophic lateral sclerosis (opens in new window)

Author(s): Giorgio Reggiardo; Maria Lo Giudice; Stefania Lalli; Gilberto Rinaldi; Alberto Albanese
Published in: Frontiers in Neurology, Issue 5, 2023, ISSN 1664-2295
Publisher: Frontiers Research Foundation
DOI: 10.3389/fneur.2023.1163855

Tauroursodeoxycholic acid in patients with amyotrophic lateral sclerosis: The TUDCA-ALS trial protocol (opens in new window)

Author(s): Alberto Albanese, Albert Christian Ludolph, Christopher J McDermott, Philippe Corcia, Philip Van Damme, Leonard H Van den Berg, Orla Hardiman, Gilberto Rinaldi, Nicola Vanacore, Brian Dickie, TUDCA-ALS Study Group (Tornese Paolo, Cocco Antoniangela, Lo Giudice Maria, Matteoli Michela, Lauranzano Eliana, Malosio Maria Luisa, Adriana Elia Chiara, Lombardo Flavia, Mayer Flavia, Puopolo Maria, Alegian
Published in: Frontiers in Neurology, Issue 16642295, 2022, ISSN 1664-2295
Publisher: Frontiers Research Foundation
DOI: 10.3389/fneur.2022.1009113

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