Objective
Many species have independently evolved similar phenotypes in response to similar environmental challenges. This phenomenon, termed convergent evolution, reflects both the power and the limits of adaptation. However, we often do not know at what scale evolution has repeated itself: did selection act on the same genes in different populations or species, or did convergence result from selection on different genes? This is because, until recently, it has not been possible to investigate the genomic basis of evolution in most systems, limiting our understanding of the factors that facilitate or inhibit convergence and adaptation. To fully understand convergent evolution we need to query the genomic response to selection and determine genotype-phenotype links in systems where convergent adaptation is well established. The Trinidadian guppy (Poecilia reticulata) is a system that offers the opportunity to test the roles of multiple factors in convergent evolution: this species includes multiple natural and experimentally established populations that have repeatedly evolved similar phenotypes under similar predation environments. I propose to fully characterize the genomic-basis of repeated adaptive evolution in guppies. Aim 1 will identify regions that repeatedly show signatures of selection, and will contrast the nature of selection in natural and experimental populations that differ in age and levels of founding genetic diversity. Aim 2 will identify genomic regions associated with phenotypes that are known to play a significant role in local adaptation in the guppy using quantitative genetics approaches. I will then directly test the effects of candidate genes using novel functional genomic approaches, as detailed in Aim 3. Overall, this project will test whether repeated selection led to convergence at the genomic level, determine the genetic basis of convergent adaptations, and ultimately understand how convergent evolution has occurred in an important wild system.
                                Fields of science (EuroSciVoc)
                                                                                                            
                                            
                                            
                                                CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See:   The European Science Vocabulary.
                                                
                                            
                                        
                                                                                                
                            CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biological behavioural sciences ethology biological interactions
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                                Keywords
                                
                                    
                                    
                                        Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
                                        
                                    
                                
                            
                            
                        Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
            Programme(s)
            
              
              
                Multi-annual funding programmes that define the EU’s priorities for research and innovation.
                
              
            
          
                      Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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                  H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
                                      MAIN PROGRAMME
                                    
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            Topic(s)
            
              
              
                Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
                
              
            
          
                      
                  Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
            Funding Scheme
            
              
              
                Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
                
              
            
          
                      Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
ERC-STG - Starting Grant
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              Call for proposal
                
                  
                  
                    Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
                    
                  
                
            
                          Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2017-STG
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
EX4 4QJ Exeter
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.
 
           
        