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Sampling Protein cOmplex Conformational Space with native top down Mass Spectrometry

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Publications

Caldendrin and myosin V regulate synaptic spine apparatus localization via ER stabilization in dendritic spines

Author(s): Anja Konietzny; Jasper Grendel; Alan Kadek; Michael Bucher; Yuhao Han; Nathalie Hertrich; Dick H W Dekkers; Jeroen A A Demmers; Kay Grünewald; Charlotte Uetrecht; Marina Mikhaylova
Published in: The EMBO Journal, 1, 2021, ISSN 1460-2075
Publisher: EMBOpress
DOI: 10.15252/embj.2020106523

Further insights from structural mass spectrometry into endocytosis adaptor protein assemblies

Author(s): Johannes Heidemann, Knut Kölbel, Albert Konijnenberg, Jeroen Van Dyck, Maria Garcia-Alai, Rob Meijers, Frank Sobott, Charlotte Uetrecht
Published in: International Journal of Mass Spectrometry, 447, 2020, Page(s) 116240, ISSN 1387-3806
Publisher: Elsevier BV
DOI: 10.1016/J.IJMS.2019.116240

Processing of the SARS-CoV pp1a/ab nsp7–10 region

Author(s): Boris Krichel, Sven Falke, Rolf Hilgenfeld, Lars Redecke, Charlotte Uetrecht
Published in: Biochemical Journal, 477/5, 2020, Page(s) 1009-1019, ISSN 0264-6021
Publisher: Portland Press, Ltd.
DOI: 10.1042/bcj20200029

Crystal structure of a domain‐swapped photoactivatable sfGFP variant provides evidence for GFP folding pathway

Author(s): Stephanie Kesgin‐Schaefer, Johannes Heidemann, Anke Puchert, Knut Koelbel, Briony A. Yorke, Nils Huse, Arwen R. Pearson, Charlotte Uetrecht, Henning Tidow
Published in: The FEBS Journal, 286/12, 2019, Page(s) 2329-2340, ISSN 1742-464X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/febs.14797

Top-Down and Bottom-Up Proteomics Methods to Study RNA Virus Biology

Author(s): Yogy Simanjuntak, Kira Schamoni-Kast, Alice Grün, Charlotte Uetrecht, Pietro Scaturro
Published in: Viruses, 2021, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13040668

X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease.

Author(s): Sebastian Günther; P. Reinke; Yaiza Fernández-García; J. Lieske; Thomas J. Lane; Helen M. Ginn; Faisal Hammad Mekky Koua; Christiane Ehrt; W. Ewert; Dominik Oberthuer; Oleksandr Yefanov; S. Meier; Kristina Lorenzen; Boris Krichel; Janine-Denise Kopicki; Luca Gelisio; W. Brehm; Ilona Dunkel; B. Seychell; Henry Gieseler; Brenna Norton-Baker; Brenna Norton-Baker; Beatriz Escudero-Pérez; M. Domara
Published in: Science, 3, 2021, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abf7945

Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes.

Author(s): Boris Krichel; Ganesh Bylapudi; C. Schmidt; Clement E. Blanchet; Robin Schubert; L. Brings; Martin Koehler; Renato Zenobi; Dmitri I. Svergun; Kristina Lorenzen; Ramakanth Madhugiri; John Ziebuhr; Charlotte Uetrecht; Charlotte Uetrecht
Published in: Science Advances, 1, 2021, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abf1004

NMR Experiments Provide Insights into Ligand-Binding to the SARS-CoV-2 Spike Protein Receptor-Binding Domain

Author(s): Robert Creutznacher; Thorben Maass; Barbora Veselkova; George Ssebyatika; Thomas Krey; Martin Empting; Norbert Tautz; Martin Frank; Knut Kölbel; Charlotte Uetrecht; Thomas Peters
Published in: Journal of the American Chemical Society, 29, 2022, Page(s) 13060-13065, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.2c05603

Structural mass spectrometry goes viral

Author(s): Jasmin Dülfer, Alan Kadek, Janine-Denise Kopicki, Boris Krichel, Charlotte Uetrecht
Published in: Complementary Strategies to Understand Virus Structure and Function, 105, 2019, Page(s) 189-238, ISBN 9780128184561
Publisher: Elsevier
DOI: 10.1016/bs.aivir.2019.07.003