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Synthetic Circuits for Robust Orthogonal Production

Objective

The repertoire of industrially produced fine chemicals in various biological systems will rapidly expand using the tools from the emerging field of synthetic biology. However, the high-level production of non-natural products or de novo activities through synthetic circuits compromises the integrity of host organisms, which significantly impacts or even prevents the development of an industrial pipeline. Our ability to exploit the potential of synthetic biology for industrial production is constrained by our understanding of the integrated cell response when introducing a new synthetic circuit into the homeostatic network of the cell. SynCrop’s main goal is to establish a European Training Network that merges the fragmented scientific expertise in theoretical, experimental and application-driven quantitative biology to educate the next generation of researchers to construct modular and tunable synthetic circuits and foster the development of novel production platforms for food additives (e.g. vitamins, carotenoids and exopolysaccharides). Researchers with inter-disciplinary skills in both experimental and computational biology are needed to solve complex application-driven problems. SynCrop brings together ten academic partners from quantitative biology, cell engineering, microbial physiology and mathematical modelling fields and six industrial partners, including key experts in metabolic engineering and industrial biotechnology. The consortium will provide 15 early-stage researchers with cutting-edge multi-disciplinary research training, through tailored research projects, rigorous exchange of expertise among researchers and partners, and participation in specialised courses, workshops and conferences augmented by extensive training in complementary skills. SynCrop will generate a strong cohort of highly-employable scientists with unique inter-disciplinary and intersectoral skills to address complex questions and develop innovative biotechnological processes.

Fields of science (EuroSciVoc)

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-ITN-ETN - European Training Networks

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-ITN-2017

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Coordinator

UNIVERSITY OF HAMBURG
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 498 432,96
Address
MITTELWEG 177
20148 Hamburg
Germany

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Region
Hamburg Hamburg Hamburg
Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 498 432,96

Participants (11)

Partners (4)

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