Resultado final
Bar-coded TCR sequence reads of human memory T cell subsets (blood and BM) (preliminary and final)
Preliminary by M36
Preliminary and validated compartmental model and code of CD8+ T cell infiltration into tumour environmentsPreliminary by M36
Reference database of immune receptor alleles in healthy humansPreliminary and validated mechanistic models of TCR repertoire dynamics and cross-reactivity
Preliminary by M36
Preliminary and validated stochastic model of the signals regulating naive T cell maintenancePreliminary by M36
Preliminary and validated mathematical model of thymic T cell development from D1.1Preliminary by M36
Renewal rates and lifespans of human T cell subsets (blood and BM) from D1.4 (preliminary and final)Preliminary by M36
A review report per WP (draft and final)A review report per WP draft and final review M36
Preliminary and validated compartmental model of human naive and memory T cell maintenancePreliminary by M36
Estimates of diversity and uniqueness of memory T cell (blood and BM) repertoires from D2.1Estimates of diversity and uniqueness of memory T cell blood and BM repertoires from D21
Labelling data of human memory T cell subsets in blood and bone marrow (BM) (preliminary and final)Preliminary by M36
Personal career development plans (in place and reviews)Reviews at M7 M19 M31
15 trained ESRs with two secondments eachPreliminary and validated probabilistic model of T cell signal integration
Preliminary by M36
Preliminary and validated computational model and code of impact of anti-cancer treatment on T cellsPreliminary by M36
Preliminary and validated computational model and code of TCR repertoire response to tumourPreliminary by M36
Two journal articles per ESRData set of thymocyte competition (preliminary and final)
Preliminary by M36
Preliminary and validated computational model of the effect of checkpoint inhibitors on T cells in cancerPreliminary by M36
Industrial workshops (S1, S2, S3, S6, S7, T8, T9 and T10) - review M21
Network meetings (E2-E6, I2-I6, B2-B5, M2-M6, T7, S4 and S5)Network meetings (E2-E6, I2-I6, B2-B5, M2-M6, T7, S4 and S5) - review M17 and M24
Complementary skill workshop (T4, T5 and T6)Recruitment strategy in place
Conferences (E1, I1, B1, M1, T1-T3)
Review M9
Publicaciones
Autores:
Léa Sta
Publicado en:
2023
Editor:
University of Leeds
Autores:
Daniel Luque Duque
Publicado en:
2023
Editor:
University of Leeds
Autores:
Giulia Belluccini
Publicado en:
2023
Editor:
University of Leeds
Autores:
HoChan Cheon
Publicado en:
2023
Editor:
Maynooth University
Autores:
Giulia Belluccini, Martın Lopez-Garcia, Grant Lythe, Carmen Molina-Paris
Publicado en:
Scientific Reports, 2022, Página(s) 12:11289, ISSN 2045-2322
Editor:
Nature Publishing Group
DOI:
10.1038/s41598-022-14202-0
Autores:
Stephan Wilmes; Polly-Anne Jeffrey; Jonathan Martinez-Fabregas; Maximillian Hafer; Paul K. Fyfe; Elizabeth Pohler; Silvia Gaggero; Martín López-García; Grant Lythe; Charles Taylor; T. Guerrier; David Launay; Suman Mitra; Jacob Piehler; Carmen Molina-París; Carmen Molina-París; Ignacio Moraga
Publicado en:
eLife, Edición 1, 2019, ISSN 2050-084X
Editor:
eLife Sciences Publications
DOI:
10.7554/elife.66014
Autores:
Mora-Bitria, L., Asquith, B
Publicado en:
Immunogenetics, 2023, Página(s) 269–282, ISSN 0093-7711
Editor:
Springer Verlag
DOI:
10.1007/s00251-023-01293-w
Autores:
Flavia Feliciangeli, Hanan Dreiwi, Martín López-García, Mario Castro Ponce, Carmen Molina-París and Grant Lythe
Publicado en:
Journal of the Royal Society Interface, Edición 17425689, 2022, Página(s) 20220629, ISSN 1742-5689
Editor:
The Royal Society
DOI:
10.1098/rsif.2022.0629
Autores:
HoChan Cheon, Andrey Kan, Giulio Prevedello, Simone C. Oostindie, Simon J. Dovedi, Edwin D. Hawkins, Julia M. Marchingo, Susanne Heinzel, Ken R. Duffy, Philip D. Hodgkin
Publicado en:
Frontiers in Bioinformatics, Edición 1, 2021, ISSN 2673-7647
Editor:
Frontiers Media SA
DOI:
10.3389/fbinf.2021.723337
Autores:
Yan Zhang, Ada W.C. Yan, Lies Boelen, Linda Hadcocks, Arafa Salam, Daniel Padrosa Gispert, Loiza Spanos, Laura Mora Bitria, Neda Nemat-Gorgani, James A. Traherne, Chrissy Roberts, Danai Koftori, Graham P. Taylor, Daniel Forton, Paul J. Norman, Steven G.E. Marsh, Robert Busch, Derek C. Macallan, and Becca Asquith
Publicado en:
The Journal of Clinical Investigation, Edición 2023;133(12):e169496, 2023, ISSN 0021-9738
Editor:
American Society for Clinical Investigation
DOI:
10.1172/jci169496
Autores:
Jessica Ann Gaevert, Daniel Luque Duque, Grant Lythe, Carmen Molina-París, Paul Glyndwr Thomas
Publicado en:
Viruses, Edición 13/9, 2021, Página(s) 1786, ISSN 1999-4915
Editor:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/v13091786
Autores:
Stefanie Scherer, Susanne G Oberle, Kristiyan Kanev, Ann-Katrin Gerullis, Ming Wu, Gustavo P de Almeida, Daniel J Puleston, Francesc Baixauli, Lilian Aly, Alessandro Greco, Tamar Nizharadze, Nils B Becker, Madlaina V Hoesslin, Lara V Donhauser, Jacqueline Berner, Talyn Chu, Hayley A McNamara, Zeynep Esencan, Patrick Roelli, Christine Wurmser, Ingo Kleiter, Maria J G T Vehreschild, Christoph A Maye
Publicado en:
Nature Communications, Edición 24(3), 2023, Página(s) 501-515, ISSN 1529-2908
Editor:
Nature Publishing Group
DOI:
10.1038/s41590-023-01436-x
Autores:
Weike Pei, Fuwei Shang, Xi Wang, Ann-Kathrin Fanti, Alessandro Greco, Katrin Busch, Kay Klapproth, Qin Zhang, Claudia Quedenau, Sascha Sauer, Thorsten B. Feyerabend, Thomas Höfer, Hans-Reimer Rodewald
Publicado en:
Cell Stem Cell, Edición 27/3, 2020, Página(s) 383-395.e8, ISSN 1934-5909
Editor:
Cell Press
DOI:
10.1016/j.stem.2020.07.018
Autores:
María Ruiz Ortega, Natanael Spisak, Thierry Mora, Aleksandra M. Walczak
Publicado en:
PLOS Genetics, 2023, ISSN 1553-7390
Editor:
Public Library of Science
DOI:
10.1371/journal.pgen.1010652
Autores:
Thomas Höfer, Hans-Reimer Rodewald
Publicado en:
Blood, Edición 132/11, 2018, Página(s) 1106-1113, ISSN 0006-4971
Editor:
American Society of Hematology
DOI:
10.1182/blood-2018-03-791517
Autores:
Luis de la Higuera, Martín López-García, Mario Castro, Niloufar Abourashchi, Grant Lythe, Carmen Molina-París
Publicado en:
Frontiers in Immunology, Edición 10, 2019, ISSN 1664-3224
Editor:
Frontiers Media SA
DOI:
10.3389/fimmu.2019.00194
Autores:
Van Thuy Truong, Paul G. Baverel, Grant D. Lythe, Paolo Vicini, James W. T. Yates, Vincent F. S. Dubois
Publicado en:
CPT: Pharmacometrics & Systems Pharmacology, 2021, ISSN 2163-8306
Editor:
Nature Publishing Group
DOI:
10.1002/psp4.12703
Autores:
Mina N. F. Morcos; Congxin Li; Clara M. Munz; Alessandro Greco; Nicole Dressel; Susanne Reinhardt; Katrin Sameith; Andreas Dahl; Nils B. Becker; Axel Roers; Thomas Höfer; Alexander Gerbaulet
Publicado en:
Nature Communications, Edición 20411723, 2022, Página(s) 4504, ISSN 2041-1723
Editor:
Nature Publishing Group
DOI:
10.1038/s41467-022-31914-z
Autores:
Suzanne Day; Charandeep Kaur; Hannah M. Cheeseman; Emily de Groot; Leon R. McFarlane; Maniola Tanaka; Sofia Coelho; Tom Cole; Nana-Marie Lemm; Adrian Lim; Rogier W. Sanders; Becca Asquith; Robin J. Shattock; Katrina M. Pollock
Publicado en:
Frontiers in Immunology, 2022, Página(s) 13:991509, ISSN 1664-3224
Editor:
Frontiers Media
DOI:
10.3389/fimmu.2022.991509
Autores:
Noor Kherreh, Siobhán Cleary, Cathal Seoighe
Publicado en:
Cancer Immunology, Immunotherapy, 2021, ISSN 0340-7004
Editor:
Springer Verlag
DOI:
10.1007/s00262-021-03028-w
Autores:
Barbara Bravi, Jérôme Tubiana, Simona Cocco, Rémi Monasson, Thierry Mora, Aleksandra M. Walczak
Publicado en:
Cell Systems, Edición 12/2, 2021, Página(s) 195-202.e9, ISSN 2405-4712
Editor:
Cell Press
DOI:
10.1016/j.cels.2020.11.005
Autores:
Chun-Yang Lin, Joshua Wolf, David C. Brice, Yilun Sun, Macauley Locke, Sean Cherry, Ashley H. Castellaw, Marie Wehenkel, Jeremy Chase Crawford, Veronika I. Zarnitsyna, Daniel Duque, Kim J. Allison, E. Kaitlynn Allen, Scott A. Brown, Alexandra H. Mandarano, Jeremie H. Estepp, The SJTRC Study Team, Charles Taylor 5, Carmen Molina-Paris, Stacey Schultz-Cherry, Li Tang, Paul G. Thomas, Maureen A. McGa
Publicado en:
Cell Host and Microbe, 2021, ISSN 1931-3128
Editor:
Cell Press
DOI:
10.1016/j.chom.2021.12.005
Autores:
Milena Simovic, Michiel Bolkestein, Mahmoud Moustafa, John K L Wong, Verena Körber, Sarah Benedetto, Umar Khalid, Hannah Sophia Schreiber, Manfred Jugold, Andrey Korshunov, Daniel Hübschmann, Norman Mack, Stephan Brons, Pei-Chi Wei, Michael O Breckwoldt, Sabine Heiland, Martin Bendszus, Jürgen Debus, Thomas Höfer, Marc Zapatka, Marcel Kool, Stefan M Pfister, Amir Abdollahi, Aurélie Ernst
Publicado en:
Neuro-Oncology, Edición Volume 23, Edición 12, December 2021, 2021, Página(s) 2028–2041, ISSN 1522-8517
Editor:
Duke University Press
DOI:
10.1093/neuonc/noab127
Autores:
Derek C. Macallan, Robert Busch, Becca Asquith
Publicado en:
Current Opinion in Systems Biology, Edición 18, 2019, Página(s) 77-86, ISSN 2452-3100
Editor:
Elsevier Ltd
DOI:
10.1016/j.coisb.2019.10.002
Autores:
C. Pixberg, M. Zapatka, M. Hlevnjak, S. Benedetto, J.P. Suppelna, J. Heil, K. Smetanay, L. Michel, C. Fremd, V. Körber, M. Rübsam, L. Buschhorn, S. Heublein, B. Schäfgen, M. Golatta, C. Gomez, A. von Au, M. Wallwiener, S. Wolf, N. Dikow, C. Schaaf, E. Gutjahr, M. Allgäuer, A. Stenzinger, K. Pfütze, R. Kirsten, D. Hübschmann, H.-P. Sinn, D. Jäger, A. Trumpp, R. Schlenk, T. Höfer, V. Thewes,
Publicado en:
ESMO Open, 2022, ISSN 2059-7029
Editor:
Elsevier
DOI:
10.1016/j.esmoop.2022.100637
Autores:
Daniel F Luque Duque, Carmen Molina-Paris, Grant Lythe, Martin Lopez Garcia, Paul Glyndwr Thomas and Jessica Gaevert
Publicado en:
The Journal of Immunology, Edición 204 (1 Supplement), 2020, Página(s) 94.18, ISSN 1550-6606
Editor:
The American Association of Immunologists, Inc.
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