Objective The development of active compounds that can efficiently fight microbial infections and cancer are of utmost importance for food security and human health, two main challenges for Europe. Tetrapyrrolic photosensitizers (PS) are good candidates to meet these expectations. These photo-excitable molecules induce cell death via the formation of oxygen reactive species (ROS) and present very low toxicity in the absence of light. They are already used in photodynamic therapy (PDT) for cancer or skin disease treatments or in photo-antimicrobial chemo-therapy (PACT). Unfortunately, the research and training are still largely fragmented in this field in Europe. Some scientific barriers have to be overcome to increase their efficacy, e.g. improvement of the excitation pathways, ROS production, specific cell targeting, Gram (-) bactericidal effect and prevention and/or eradication of biofilms. That is why the EJD Polythea project aims developing an integrated and multidisciplinary approach of PDT through the implementation of 10 PhD research projects. The Polythea consortium proposes to develop (i) new tetrapyrrolic PS for various types of PDT including anti-cancer, anti-bacterial, anti-inflammatory and immune-activating application, improving their photophysical and biological properties; and (ii) innovative bio-inspired drug carriers or supports.In parallel, a joint doctorate structure gathering 5 countries will be created and a multidisciplinary and inter-sectorial training programme will be implemented through network events and secondments to non-academic partners. It will provide a common background on PDT to the ESRs and make them more valuable employees, effective at problem solving. Practical applications should come out of this project such as first aid bandages, new skin/anti-tumour treatments, self-sterilizing surfaces for food industry or prosthetic devices. Fields of science medical and health scienceshealth sciencesnutritionmedical and health sciencesclinical medicineoncologymedical and health sciencesmedical biotechnologyimplants Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.1. - Fostering new skills by means of excellent initial training of researchers Topic(s) MSCA-ITN-2017 - Innovative Training Networks Call for proposal H2020-MSCA-ITN-2017 See other projects for this call Funding Scheme MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN) Coordinator UNIVERSITE DE LIMOGES Net EU contribution € 525 751,20 Address François mitterrand 33 87032 Limoges France See on map Region Nouvelle-Aquitaine Limousin Haute-Vienne Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Participants (6) Sort alphabetically Sort by Net EU contribution Expand all Collapse all THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN Ireland Net EU contribution € 797 023,80 Address College green trinity college D02 CX56 Dublin 2 See on map Region Ireland Eastern and Midland Dublin Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 POLITECHNIKA WROCLAWSKA Poland Net EU contribution € 224 137,44 Address Wybrzeze wyspianskiego 27 50-370 Wroclaw See on map Region Makroregion południowo-zachodni Dolnośląskie Miasto Wrocław Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITEIT VAN AMSTERDAM Netherlands Net EU contribution € 255 374,28 Address Spui 21 1012WX Amsterdam See on map Region West-Nederland Noord-Holland Groot-Amsterdam Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSIDADE DE COIMBRA Portugal Net EU contribution € 238 356,36 Address Paco das escolas 3004-531 Coimbra See on map Region Continente Centro (PT) Região de Coimbra Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITE DE NEUCHATEL Switzerland Net EU contribution € 265 226,76 Address Faubourg de l'hopital 41 2000 Neuchatel See on map Region Schweiz/Suisse/Svizzera Espace Mittelland Neuchâtel Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 BIOEMISSION TECHNOLOGY SOLUTIONS IKE Greece Net EU contribution € 242 386,92 Address L. mesogeion 387 153 43 Agia paraskevi (athina) See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Αττική Aττική Βόρειος Τομέας Αθηνών Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00
