Resultado final
Define epigenetic signature of the placenta in the context of early/late onset PE with and without IUGR.
Define epigenetic signature of the placenta in the context of earlylate onset PE with and without IUGR
Report on dissemination strategy of project results to scientific community, updated annually - No. 2Report on dissemination strategy of project results to scientific community updated annually No 2
All ESRs published 3 scientific papers (2 first author) and 1 joint review per year - No. 3All ESRs published 3 scientific papers 2 first author and 1 joint review per year No 3
Determine genetic signature using genome-wide technologies genotyping of maternal circulation, cord blood and placental tissue, gene expression in PE and IUGR patients.Determine genetic signature using genomewide technologies genotyping of maternal circulation cord blood and placental tissue gene expression in PE and IUGR patients
Determining ncRNA in biopsies and extracellular vesicle cargo as a natural placental biopsy for disesed pregnanciesReport on dissemination strategy of project results to scientific community, updated annually - No. 1
Longitudinal documentation of hemodynamic effects of IUGR model in animals; correlation to morphologic analysis of selected fetal organs
Longitudinal documentation of hemodynamic effects of IUGR model in animals correlation to morphologic analysis of selected fetal organs
Assessment of a metabolic signature in the maternal and fetal (placental) circulation and in vivo models of preeclampsia and IUGR and correlated to clinical and genomic outcomes.Assessment of a metabolic signature in the maternal and fetal placental circulation and in vivo models of preeclampsia and IUGR and correlated to clinical and genomic outcomes
Annual Management Reports - No. 2Validation of novel ultrasound tools to diagnose complicated pregnancies through imaging fetal cardiovascular function in relation to maternal cardiovascular function
All ESRs published 3 scientific papers (2 first author) and 1 joint review per year - No. 2
All ESRs published 3 scientific papers 2 first author and 1 joint review per year No 2
Report on dissemination strategy of project results to scientific community, updated annually - No. 3Report on dissemination strategy of project results to scientific community updated annually No 3
Annual Management Reports - No. 3Annual Management Reports No 3
Characterisation and standardisation of murine PE model with validation of in vivo tools (iontophoresis & endoscopic laser speckle imager)Characterisation and standardisation of murine PE model with validation of in vivo tools iontophoresis endoscopic laser speckle imager
All ESRs published 3 scientific papers (2 first author) and 1 joint review per year - No. 1Assessment of the use of functional fetal brain MRI and CPR to identify fetoplacental biomarkers for prediction of IUGR
Annual Management Reports - No. 4
Annual Management Reports No 4
Validation of targets minimum 3 targets identified in WP2 by ESR5 67 8 in placentaonachip models
All ESRs presented at international conferences (2 per annum) - No. 1All ESRs presented at international conferences (2 per annum) -No. 1
Graduation of all ESRs with PhDsGenomic and expression profile (surface/angiogenic markers) of placental derived EVs from explants, organ-on-a-chip model, and human amniotic fluid and blood
Genomic and expression profile surfaceangiogenic markers of placental derived EVs from explants organonachip model and human amniotic fluid and blood
All ESRs presented at international conferences (2 per annum) - No. 3All ESRs presented at international conferences 2 per annum No 3
Generation and characterisation of 4-stable endothelial & trophoblast lines via CRISPR gene editing to mimic IUGR/PEGeneration and characterisation of 4stable endothelial trophoblast lines via CRISPR gene editing to mimic IUGRPE
All ESRs presented at international conferences (2 per annum) - No. 2All ESRs presented at international conferences 2 per annum No 2
Publicaciones
Autores:
Charles G. Bailey; Shailendra Gupta; Cynthia Metierre; Punkaja M. S. Amarasekera; Patrick O’Young; Wunna Kyaw; Tatyana Laletin; Habib Francis; Crystal Semaan; Mehdi Sharifi Tabar; Krishna P. Singh; Charles G. Mullighan; Olaf Wolkenhauer; Ulf Schmitz; John E. J. Rasko
Publicado en:
Crossref, Edición 4, 2021, Página(s) 7519-7536, ISSN 0014-4754
Editor:
Springer
DOI:
10.1007/s00018-021-03946-z
Autores:
Ottaviani L, Juni RP, de Abreu RC, Sansonetti M, Sampaio-Pinto V, Halkein J, Hegenbarth JC, Ring N, Knoops K, Kocken JMM, Jesus C, Ernault AC, El Azzouzi H, Rühle F, Olieslagers S, Fernandes H, Ferreira L, Braga L, Stoll M, Nascimento DS, de Windt LJ, da Costa Martins PA.
Publicado en:
Molecular Therapy, 2022, ISSN 1525-0016
Editor:
Nature Publishing Group
DOI:
10.1016/j.ymthe.2022.03.002
Autores:
V. Giorgione, F. D'Antonio, A. Manji, K. Reed, A. Khalil
Publicado en:
Ultrasound in Obstetrics & Gynecology, 2021, ISSN 0960-7692
Editor:
John Wiley & Sons Inc.
DOI:
10.1002/uog.23585
Autores:
Veronica Giorgione, Anna Ridder, Erkan Kalafat, Asma Khalil, Basky Thilaganathan
Publicado en:
BJOG: An International Journal of Obstetrics & Gynaecology, 2020, ISSN 1470-0328
Editor:
Blackwell Publishing Inc.
DOI:
10.1111/1471-0528.16545
Autores:
Morales-Roselló J, Loscalzo G, García-Lopez EM, García-Gimenez JL, Perales-Marín A
Publicado en:
Health Sci Rep, 2022, ISSN 2398-8835
Editor:
John Wiley & Sons
DOI:
10.1002/hsr2.558
Autores:
Gabriela Loscalzo; Julia Scheel; José Santiago Ibañez-Cabellos; Eva García-Lopez; Shailendra Gupta; José Luis García-Gimenez; Salvador Mena-Mollá; Alfredo Perales-Marín; José Morales-Roselló
Publicado en:
International Journal of Molecular Sciences, Vol 23, Iss 293, p 293 (2022), Edición 3, 2021, ISSN 1422-0067
Editor:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/ijms23010293
Autores:
B. S. Buddeberg, R. Sharma, J. M. O'Driscoll, A. Kaelin Agten, A. Khalil, B. Thilaganathan
Publicado en:
Ultrasound in Obstetrics & Gynecology, Edición 56/2, 2020, Página(s) 240-246, ISSN 0960-7692
Editor:
John Wiley & Sons Inc.
DOI:
10.1002/uog.21941
Autores:
Charles N. Serhan, Shailendra K. Gupta, Mauro Perretti, Catherine Godson, Eoin Brennan, Yongsheng Li, Oliver Soehnlein, Takao Shimizu, Oliver Werz, Valerio Chiurchiù, Angelo Azzi, Marc Dubourdeau, Suchi Smita Gupta, Patrick Schopohl, Matti Hoch, Dragana Gjorgevikj, Faiz M. Khan, David Brauer, Anurag Tripathi, Konstantin Cesnulevicius, David Lescheid, Myron Schultz, Eva Särndahl, Dirk Repsilber,
Publicado en:
Molecular Aspects of Medicine, Edición 74, 2020, Página(s) 100894, ISSN 0098-2997
Editor:
Pergamon Press Ltd.
DOI:
10.1016/j.mam.2020.100894
Autores:
Camino S. M. Ruano, Clara Apicella, Sébastien Jacques, Géraldine Gascoin, Cassandra Gaspar, Francisco Miralles, Céline Méhats & Daniel Vaiman
Publicado en:
Human Genetics, 2021, ISSN 1432-1203
Editor:
Springer
DOI:
10.1007/s00439-020-02248-x
Autores:
Gebara, N., Scheel, J., Skovronova, R., Grange, C., Marozio, L., Gupta, S., Giorgione, V., Caicci, F., Benedetto, C., Khalil, A., & Bussolati, B.
Publicado en:
Journal of Extracellular Vesicles, 2022, ISSN 2001-3078
Editor:
Wiley for the International Society for Extracellular Vesicles
DOI:
10.1002/jev2.12217
Autores:
Manna, S.; Ruano, C.S.M.; Hegenbarth, J.-C.; Vaiman, D.; Gupta, S.; McCarthy, F.P.; Méhats, C.; McCarthy, C.; Apicella, C.; Scheel, J.
Publicado en:
Antioxidants (Basel), 2022, ISSN 2076-3921
Editor:
MDPI
DOI:
10.3390/antiox11030585
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EG Mulder, C Ghossein‐Doha, JRW Crutsen, SMJ Van Kuijk, B Thilaganathan, MEA Spaanderman
Publicado en:
BJOG: An International Journal of Obstetrics & Gynaecology, Edición 128/1, 2021, Página(s) 121-129, ISSN 1470-0328
Editor:
Blackwell Publishing Inc.
DOI:
10.1111/1471-0528.16435
Autores:
Hegenbarth Jana-Charlotte, Lezzoche Giuliana, De Windt Leon J., Stoll Monika
Publicado en:
Frontiers in Molecular Medicine, 2022, ISSN 2674-0095
Editor:
Lausanne Frontiers Media SA
DOI:
10.3389/fmmed.2022.839338
Autores:
Clara Apicella, Camino S. M. Ruano, Sébastien Jacques, Géraldine Gascoin, Céline Méhats, Daniel Vaiman, Francisco Miralles
Publicado en:
Frontiers in Cell and Developmental Biology, Edición 9, 2021, ISSN 2296-634X
Editor:
Frontiers Media
DOI:
10.3389/fcell.2021.633937
Autores:
Veronica Giorgione, Amar Bhide, Rohan Bhate, Keith Reed, Asma Khalil
Publicado en:
Journal of Clinical Medicine, Edición 9/10, 2020, Página(s) 3276, ISSN 2077-0383
Editor:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/jcm9103276
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Dongqing Guo, Colin E. Murdoch, Tianhua Liu, Jia Qu, Shihong Jiao, Yong Wang, Wei Wang, Xing Chen
Publicado en:
Frontiers in Pharmacology, Edición 9, 2018, ISSN 1663-9812
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Frontiers Media S.A.
DOI:
10.3389/fphar.2018.00428
Autores:
Samprikta Manna, Cathal McCarthy, Fergus P. McCarthy
Publicado en:
Oxidative Medicine and Cellular Longevity, Edición 2019, 2019, Página(s) 1-11, ISSN 1942-0900
Editor:
Landes Bioscience
DOI:
10.1155/2019/3095383
Autores:
Basky Thilaganathan, Erkan Kalafat
Publicado en:
Hypertension, Edición 73/3, 2019, Página(s) 522-531, ISSN 0194-911X
Editor:
Lippincott Williams & Wilkins Ltd.
DOI:
10.1161/hypertensionaha.118.11191
Autores:
Anna Ridder, Veronica Giorgione, Asma Khalil, Basky Thilaganathan
Publicado en:
International Journal of Molecular Sciences, Edición 20/13, 2019, Página(s) 3263, ISSN 1422-0067
Editor:
Multidisciplinary Digital Publishing Institute (MDPI)
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10.3390/ijms20133263
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Clara Apicella, Camino S. M. Ruano, Céline Méhats, Francisco Miralles, Daniel Vaiman
Publicado en:
International Journal of Molecular Sciences, Edición 20/11, 2019, Página(s) 2837, ISSN 1422-0067
Editor:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/ijms20112837
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Publicado en:
Antioxidants, Edición 8/8, 2019, Página(s) 315, ISSN 2076-3921
Editor:
Antioxidants
DOI:
10.3390/antiox8080315
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Karen Melchiorre, Basky Thilaganathan, Veronica Giorgione, Anna Ridder, Alessia Memmo, Asma Khalil
Publicado en:
Frontiers in Cardiovascular Medicine, Edición 7, 2020, ISSN 2297-055X
Editor:
Frontiers Media
DOI:
10.3389/fcvm.2020.00059
Autores:
Natalia Gebara, Andrea Rossi, Renata Skovronova, Justine Mariam Aziz, Amish Asthana, Benedetta Bussolati
Publicado en:
Current Transplantation Reports, Edición 2020, 2020, ISSN 2196-3029
Editor:
Springer Nature
DOI:
10.1007/s40472-020-00282-2
Autores:
Aurélien Ducat, Betty Couderc, Anthony Bouter, Louise Biquard, Rajaa Aouache, Bruno Passet, Ludivine Doridot, Marie-Benoîte Cohen, Pascale Ribaux, Clara Apicella, Irène Gaillard, Sophia Palfray, Yulian Chen, Alexandra Vargas, Amélie Julé, Léo Frelin, Julie Cocquet, Camino Ruano San Martin, Sébastien Jacques, Florence Busato, Jorg Tost, Céline Méhats, Paul Laissue, Jean-Luc Vilotte, Franci
Publicado en:
iScience, Edición 23/5, 2020, Página(s) 101086, ISSN 2589-0042
Editor:
Cell Press
DOI:
10.1016/j.isci.2020.101086
Autores:
Kristin Kräker, Till Schütte, Jamie O’Driscoll, Anna Birukov, Olga Patey, Florian Herse, Dominik N. Müller, Basky Thilaganathan, Nadine Haase, Ralf Dechend
Publicado en:
International Journal of Molecular Sciences, Edición 21/3, 2020, Página(s) 1162, ISSN 1422-0067
Editor:
Multidisciplinary Digital Publishing Institute (MDPI)
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10.3390/ijms21031162
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Publicado en:
Fetal Diagn Ther, 2022, ISSN 1015-3837
Editor:
S. Karger AG
DOI:
10.1159/000525162
Autores:
Veronica Giorgione, Corey Briffa, Carolina Di Fabrizio, Rohan Bhate, Asma Khalil
Publicado en:
Journal of Clinical Medicine, Edición 10/4, 2021, Página(s) 643, ISSN 2077-0383
Editor:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/jcm10040643
Autores:
Ostaszewski, Marek; Niarakis, Anna; Mazein, Alexander; Kuperstein, Inna; Phair, Robert; Orta-Resendiz, Aurelio; Singh, Vidisha; Aghamiri, Sara,; Acencio, Marcio,; Glaab, Enrico; Ruepp, Andreas; Fobo, Gisela; Montrone, Corinna; Brauner, Barbara; Frishman, Goar; Monraz Gómez, Luis Cristóbal; Somers, Julia; Hoch, Matti; Kumar Gupta, Shailendra; Scheel, Julia; Borlinghaus, Hanna; Czauderna, Tobias;
Publicado en:
Molecular Systems Biology, Vol 17, Iss 10, Pp n/a-n/a (2021), Edición 6, 2021, Página(s) e10387, ISSN 1744-4292
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Nature Publishing Group
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10.17863/cam.77076
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Morales-Roselló J, Galindo A, Scarinci E, Herraiz I, Buongiorno S, Loscalzo G, Gómez Arriaga PI, Cañada Martínez AJ, Rosati P, Lanzone A, Perales Marín A
Publicado en:
J Obstet Gynaecol., 2022, ISSN 0144-3615
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Taylor & Francis
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10.1080/01443615.2021.1998891
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De Majo, F., Martens, L., Hegenbarth, J. C., Rühle, F., Hamczyk, M. R., Nevado, R. M., Andrés, V., Hilbold, E., Bär, C., Thum, T., de Boer, M., Duncker, D. J., Schroen, B., Armand, A. S., Stoll, M., & De Windt, L. J.
Publicado en:
PNAS, 2021, ISSN 0027-8424
Editor:
National Academy of Sciences
DOI:
10.1073/pnas.2022974118
Autores:
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Publicado en:
J Matern Fetal Neonatal Med, 2022, ISSN 1476-7058
Editor:
Parthenon Publishing Group
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10.1080/14767058.2022.2057794
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D. Basurto, N. Sananès, E. Verbeken, D. Sharma, E. Corno, I. Valenzuela, L. Van Der Veeken, R. Favre, F. M. Russo, J. Deprest
Publicado en:
Ultrasound in Obstetrics & Gynecology, 2020, ISSN 0960-7692
Editor:
John Wiley & Sons Inc.
DOI:
10.1002/uog.22132
Autores:
Natalia Gebara, Yolanda Correia, Keqing Wang, Benedetta Bussolati
Publicado en:
International Journal of Molecular Sciences, Edición 22/10, 2021, Página(s) 5402, ISSN 1422-0067
Editor:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/ijms22105402
Autores:
Conrado Milani Coutinho; Conrado Milani Coutinho; V. Giorgione; Laure Noel; Becky Liu; Edwin Chandraharan; J. Pryce; A. P. Frick; Baskaran Thilaganathan; Baskaran Thilaganathan; Amar Bhide
Publicado en:
Ultrasound in Obstetrics & Gynecology, Edición 5, 2021, ISSN 1469-0705
Editor:
Wiley
DOI:
10.1002/uog.23100
Autores:
De Majo F, Hegenbarth JC, Rühle F, Bär C, Thum T, de Boer M, Duncker DJ, Schroen B, Armand AS, Stoll M, De Windt LJ.
Publicado en:
Scientific Reports, 2020, ISSN 2045-2322
Editor:
Nature Publishing Group
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10.1038/s41598-020-65115-9
Autores:
Gwenaёlle Rabussier, Ivan Bünter, Josse Bouwhuis, Camilla Soragni, Chee Ping Ng, Karel Dormansky, Leon J. de Windt, Paul Vulto, Colin E. Murdoch, Kristin M. Bircsak, Henriёtte L. Lanz
Publicado en:
2022
Editor:
NA
DOI:
10.1101/2022.06.30.498115
Autores:
iPLACENTA Symposium Committee
Publicado en:
2021
Editor:
iPLACENTA
DOI:
10.5281/zenodo.4954997
Autores:
Morales-Roselló, José; Loscalzo, Gabriela; Perez, Gemma; Soriano Paya, Alicia; Jakaitė, Vaidilė; Perales Marín, Alfredo
Publicado en:
The Journal of Maternal-Fetal & Neonatal Medicine, 2021
Editor:
Zenodo (preprint)
DOI:
10.5281/zenodo.5006139
Autores:
Morales-Roselló, José; García Gimenez, José Luis; Martinez Priego, Llucia; González-Rodríguez, Daymé; Mena-Mollá, Salvador; Maquieira Catalá, Angel; Loscalzo, Gabriela; Buongiorno, Silvia; Jakaite, Vaidile; Cañada Martínez, Antonio José; Perales Marín, Alfredo
Publicado en:
Fetal Diagnosis and Therapy, 2021
Editor:
Zenodo (pre-print)
DOI:
10.5281/zenodo.4059846
Autores:
Serhan, Charles N.; Gupta, Shailendra; Perretti, Mauro; Godson, Catherine; Brennan, Eoin; Li, Yongsheng; Soehnlein, Oliver; Shimizu, Takao; Werz, Oliver; Chiurchiù, Valerio; Azzi, Angelo; Dubourdeau, Marc; Gupta, Suchi Smita; Schopohl, Patrick; Hoch, Matti; Gjorgevikj, Dragana; Khan, Faiz M.; Brauer, David; Tripathi, Anurag; Cesnulevicius, Konstantin; Lescheid, David; Schultz, Myron; Repsilber, D
Publicado en:
biorxiv, Edición 4, 2021, Página(s) 1, ISSN 2692-8205
Editor:
biorxiv
DOI:
10.1101/2020.01.27.921882
Autores:
Markwalder L, Sneddon C, Gush R, Krstajic N, Murdoch C
Publicado en:
Physiology 2021 Abstract Book, Edición 12-16 July 2021, 2021
Editor:
Physiology
Autores:
Agathe Lermant, Claire Sneddon, Jack Hanna, Lukas Markwalder, Colin E Murdoch
Publicado en:
Heart Journal - SCF, 2020, Página(s) A7.1-A7
Editor:
BMJ Publishing Group Ltd and British Cardiovascular Society
DOI:
10.1136/heartjnl-2020-scf.14
Autores:
Natalia Gebara, Corinne Lampietro, Benedetta Bussolati, Chiara Benedetto and Luca Marozio
Publicado en:
ISEV2019 Abstract Book, in Journal of Extracellular Vesicles, Edición 8/sup1, 2019
Editor:
Taylor and Francis
Autores:
Scheel, Julia & Gupta, Shailendra & Wolkenhauer, Olaf.
Publicado en:
Placenta, Edición 112, 2021, Página(s) e35, ISSN 0143-4004
Editor:
W. B. Saunders Co., Ltd.
DOI:
10.1016/j.placenta.2021.07.114
Autores:
Loscalzo G, Moralles-Roselló J, García Gimenez JL, Martinez Priego L, González-Rodríguez D, Mena Mollá S, Maquieira Catalá A, Buongiorno S, Cañada Martínez AJ, Perales Marín A
Publicado en:
8th International Conference on Fetal Growth, Edición 2019, 2019, Página(s) Abstract 28
Editor:
Perinatal Institute
Autores:
Soragni C, Rabussier G, Lanz HL, de Windt LJ, Trietsch SJ, Ng CP
Publicado en:
International Cell Culture Under Flow Meeting 2020, Abstract Book, Edición 2020, 2020
Editor:
Biomedical Center Munich
Autores:
José Morales‐Roselló, Gabriela Loscalzo, Silvia Buongiorno, Vaidilė Jakaitė, Alfredo Perales‐Marín
Publicado en:
BJOG: An International Journal of Obstetrics & Gynaecology, 2020, ISSN 1470-0328
Editor:
Blackwell Publishing Inc.
DOI:
10.1111/1471-0528.16376
Autores:
I. Couck, I. Valenzuela, F. Russo, L. Lewi
Publicado en:
Ultrasound in Obstetrics & Gynecology, Edición 55/6, 2020, Página(s) 839-840, ISSN 0960-7692
Editor:
John Wiley & Sons Inc.
DOI:
10.1002/uog.21897
Autores:
Andre Gie, Ignacio Valenzuela, Thomas Salaets, Jan Deprest, Jaan Toelen
Publicado en:
Tantalizing Therapeutics in Bronchopulmonary Dysplasia, 2020, Página(s) 169-191, ISBN 9780128189870
Editor:
Elsevier
DOI:
10.1016/b978-0-12-818987-0.00009-6
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