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Interdisciplinary training network on the purinergic P2X7 receptor to control neuroinflammation and hyperexcitability in brain diseases.

Deliverables

Network-wide training events M24

Workshop on “Clinical techniques and challenges in patient treatment – from Birth to Old Age” and “Good Clinical Practice” (3 days, open to scientific audience; ~ 100 participants); Workshop “Drug design – from Target genes to Medicine” (2 days, open to scientific audience; ~ 30 participants)

Network-wide training events M8

Introduction Programme: “Brain diseases and purinergic signalling” (2 days, open to scientific audience, ~100 participants); Transferable skills course I: “Essential Project Management” & “Innovative & Entrepreneurial Working Groups” (2 days, ESRs)

Network-wide training events M12

Workshop “Animal experimentation & behaviour assessment” (3 days, open to scientific audience, ~ 50 participants); Transferable skills course II: “Basic Research Skills & Introduction to web-based learning” (2 days, ESRs)

Report on communication and public engagement activities M12

Report on communication and public engagement activities

Report on gender equality in PurinesDX M12

Report on gender equality in PurinesDX

Report on communication and public engagement activities M6

Report on communication and public engagement activities

Risk protocol M18

Risk protocol

Report on gender equality in PurinesDX M24

Report on gender equality in PurinesDX

Network-wide training events M18

First Annual Meeting (data presentation) (1 day, ESRs); Workshop: “In vivo imaging” (1 day, ESRs); Transferable skills course III: “Research Communication and Dissemination” (2 days, ESRs)

Report on communication and public engagement activities M24

Report on communication and public engagement activities

Dissemination diary and report of dissemination events M24

Dissemination diary and report of dissemination events

Dissemination diary and report of dissemination events M12

Dissemination diary and report of dissemination events

Supervisory Board of the network

Supervisory Board members of the network

Recruitment completion and ESR contracts

Recruitment completion and ESR contracts

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Publications

Amyloid Peptide Induced Neuroinflammation Increases the P2X7 Receptor Expression in Microglial Cells, Impacting on Its Functionality

Author(s): Carlos Martínez-Frailes, Caterina Di Lauro, Carolina Bianchi, Laura de Diego-García, Álvaro Sebastián-Serrano, Lisardo Boscá, Miguel Díaz-Hernández
Published in: Frontiers in Cellular Neuroscience, Issue 13, 2019, ISSN 1662-5102
DOI: 10.3389/fncel.2019.00143

The ASIC3/P2X3 cognate receptor is a pain-relevant and ligand-gated cationic channel

Author(s): Gabriele Stephan, Lumei Huang, Yong Tang, Sandra Vilotti, Elsa Fabbretti, Ye Yu, Wolfgang Nörenberg, Heike Franke, Flóra Gölöncsér, Beáta Sperlágh, Anke Dopychai, Ralf Hausmann, Günther Schmalzing, Patrizia Rubini, Peter Illes
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
DOI: 10.1038/s41467-018-03728-5

MicroRNA-22 Controls Aberrant Neurogenesis and Changes in Neuronal Morphology After Status Epilepticus

Author(s): Edward H. Beamer, Jeronimo Jurado-Arjona, Eva M. Jimenez-Mateos, James Morgan, Cristina R. Reschke, Aidan Kenny, Gioacchino de Leo, Luis A. Olivos-Oré, Marina Arribas-Blázquez, Stephen F. Madden, Jesús Merchán-Rubira, Norman Delanty, Michael A. Farrell, Donncha F. O’Brien, Jesus Avila, Miguel Diaz-Hernandez, M. Teresa Miras-Portugal, Antonio R. Artalejo, Felix Hernandez, David C. Henshall, T
Published in: Frontiers in Molecular Neuroscience, Issue 11, 2018, ISSN 1662-5099
DOI: 10.3389/fnmol.2018.00442