How cellular suicide programmes control phase transitions in fatty liver disease and liver cancer

Información del proyecto

PhaseControl

Identificador del acuerdo de subvención: 771083

DOI

10.3030/771083

Proyecto cerrado

Fecha de la firma de la CE 15 Mayo 2018

Fecha de inicio 1 Noviembre 2018

Fecha de finalización 30 Abril 2025

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 1 997 840,00

Aportación de la UE

€ 1 997 840,00

Coordinado por

HEINRICH-HEINE-UNIVERSITAET DUESSELDORF
Germany

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (40)

Differential role of chronic liver diseases on the incidence of cancer: a longitudinal analysis among 248,224 outpatients in Germany

Autores: Sven H Loosen, David Schöler, Mark Luedde, Johannes Eschrich, Tom Luedde, Karel Kostev, Christoph Roderburg
Publicado en: Journal of Cancer Research and Clinical Oncology, 2022, ISSN 0171-5216
Editor: Springer Verlag
DOI: 10.1007/s00432-022-04198-5

The association between the body height and cardiovascular diseases: a retrospective analysis of 657,310 outpatients in Germany

Autores: Sarah Krieg, Karel Kostev, Mark Luedde, Andreas Krieg, Tom Luedde, Christoph Roderburg, Sven H Loosen
Publicado en: European Journal of Medical Research, Edición 27/1, 2022, Página(s) 240, ISSN 0949-2321
Editor: Holzapfel Verlag GmbH
DOI: 10.1186/s40001-022-00881-y

Deep learning in cancer pathology: a new generation of clinical biomarkers

Autores: Amelie Echle, Niklas Timon Rindtorff, Titus Josef Brinker, Tom Luedde, Alexander Thomas Pearson, Jakob Nikolas Kather
Publicado en: British Journal of Cancer, Edición 124, 2023, Página(s) 686-696, ISSN 0007-0920
Editor: Nature Publishing Group
DOI: 10.1038/s41416-020-01122-x

Circulating Osteopontin Levels and Outcomes in Patients Hospitalized for COVID-19

Autores: Salim S Hayek, Christoph Roderburg, Pennelope Blakely, Christopher Launius, Jesper Eugen-Olsen, Frank Tacke, Sofia Ktena, Verena Keitel, Mark Luedde, Evangelos J Giamarellos-Bourboulis, Tom Luedde, Sven H Loosen
Publicado en: Journal of Clinical Medicine, Edición 10/17, 2021, Página(s) 3907, ISSN 2077-0383
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10173907

An NF-kappaB- and IKK-Independent Function of NEMO Prevents Hepatocarcinogenesis by Suppressing Compensatory Liver Regeneration

Autores: Koppe, Reisinger, Wehr, Vucur, Trautwein, Tacke, Heikenwalder, Luedde
Publicado en: Cancers, Edición 11/7, 2019, Página(s) 999, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11070999

An Elevated FIB-4 Score Is Associated with an Increased Incidence of Depression among Outpatients in Germany

Autores: David Schöler; Karel Kostev; Münevver Demir; Mark Luedde; Marcel Konrad; Tom Luedde; Christoph Roderburg; Sven H. Loosen
Publicado en: Journal of Clinical Medicine, Edición 11/8, 2022, Página(s) 2214, ISSN 2077-0383
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm11082214

Hospital Mortality and Current Trends in Liver Transplantation in Germany — a Systematic Analysis of Standardized Hospital Discharge Data, 2008–2017

Autores: Sven H Loosen, Hans H Bock, Martin Hellmich, Wolfram T. Knoefel, Christian Trautwein, Verena Keitel, Johannes G. Bode, Ulf P. Neumann, Tom Luedde
Publicado en: Deutsches Ärzteblatt International, Edición 118/29-30, 2021, Página(s) 497-502, ISSN 1866-0452
Editor: Deutscher Arzte-Verlag
DOI: 10.3238/arztebl.m2021.0210

Golgi Protein 73 (GP73) Serum Levels Predict Outcome after Resection of Biliary Tract Cancer

Autores: Sven H Loosen, Justus Halpaap, Simon Labuhn, Jan Bednarsch, Patrick H Alizai, Anjali A Roeth, Sven A Lang, Mihael Vucur, Jakob N Kather, Wolfram T Knoefel, Tom F Ulmer, Ulf P Neumann, Christoph Roderburg, Tom Luedde
Publicado en: Cancers, Edición 14/18, 2022, Página(s) 4428, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14184428

Perception of the 2020 SARS-CoV-2 pandemic among medical professionals in Germany: results from a nationwide online survey

Autores: Pia Paffenholz, Arne Peine, Martin Hellmich, Stella V. Paffenholz, Lukas Martin, Mark Luedde, Miriam Haverkamp, Christoph Roderburg, Gernot Marx, Axel Heidenreich, Christian Trautwein, Tom Luedde, Sven H. Loosen
Publicado en: Emerging Microbes & Infections, Edición 9/1, 2020, Página(s) 1590-1599, ISSN 2222-1751
Editor: Nature Publishing Group
DOI: 10.1080/22221751.2020.1785951

Telomere Shortening in Peripheral Leukocytes Is Associated With Poor Survival in Cancer Patients Treated With Immune Checkpoint Inhibitor Therapy

Autores: Benjamin Rolles, Joao Gorgulho, Mareike Tometten, Christoph Roderburg, Margherita Vieri, Anne Abels, Mihael Vucur, Felix Heymann, Frank Tacke, Tim H Brümmendorf, Tom Luedde, Fabian Beier, Sven H Loosen
Publicado en: Frontiers in Oncology, Edición 11, 2021, Página(s) 729207, ISSN 2234-943X
Editor: Frontiers Media S. A.
DOI: 10.3389/fonc.2021.729207

Factors Associated with Non-Severe Adverse Reactions after Vaccination against SARS-CoV-2: A Cohort Study of 908,869 Outpatient Vaccinations in Germany

Autores: Sven H Loosen, Jens Bohlken, Kerstin Weber, Marcel Konrad, Tom Luedde, Christoph Roderburg, Karel Kostev
Publicado en: Vaccines, Edición 10/4, 2022, Página(s) 566, ISSN 2076-393X
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines10040566

A decision point between transdifferentiation and programmed cell death priming controls KRAS-dependent pancreatic cancer development

Autores: Anne T. Schneider, Christiane Koppe, Emilie Crouchet, Aristeidis Papargyriou, Michael T. Singer, Veronika Büttner, Leonie Keysberg, Marta Szydlowska, Frank Jühling, Julien Moehlin, Min-Chun Chen, Valentina Leone, Sebastian Mueller, Thorsten Neuß, Mirco Castoldi, Marina Lesina, Frank Bergmann, Thilo Hackert, Katja Steiger, Wolfram T. Knoefel, Alex Zaufel, Jakob N. Kather, Irene Esposito, Matthia
Publicado en: Nature Communications, Edición 16, 2025, Página(s) 1765, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-025-56493-7

Obesity and lipid metabolism disorders determine the risk for development of long COVID syndrome: a cross-sectional study from 50,402 COVID-19 patients

Autores: Sven H Loosen, Björn-Erik Ole Jensen, Christian Tanislav, Tom Luedde, Christoph Roderburg, Karel Kostev
Publicado en: Infection, 2022, Página(s) 1-6, ISSN 0300-8126
Editor: Urban und Vogel Medien und Medizin Verlagsgesellschaft mbH
DOI: 10.1007/s15010-022-01784-0

Pan-cancer image-based detection of clinically actionable genetic alterations

Autores: Jakob Nikolas Kather, Lara R. Heij, Heike I. Grabsch, Chiara Loeffler, Amelie Echle, Hannah Sophie Muti, Jeremias Krause, Jan M. Niehues, Kai A. J. Sommer, Peter Bankhead, Loes F. S. Kooreman, Jefree J. Schulte, Nicole A. Cipriani, Roman D. Buelow, Peter Boor, Nadina Ortiz-Brüchle, Andrew M. Hanby, Valerie Speirs, Sara Kochanny, Akash Patnaik, Andrew Srisuwananukorn, Hermann Brenner, Michael Hoff
Publicado en: Nature Cancer, Edición 1/8, 2020, Página(s) 789-799, ISSN 2662-1347
Editor: Springer Nature
DOI: 10.1038/s43018-020-0087-6

Soluble and EV-bound CD27 act as antagonistic biomarkers in patients with solid tumors undergoing immunotherapy

Autores: Joao Gorgulho, Sven H. Loosen, Ramsha Masood, Franziska Giehren, Francesca Pagani, Gustav Buescher, Lorenz Kocheise, Vincent Joerg, Constantin Schmidt, Kornelius Schulze, Christoph Roderburg, Eva Kinkel, Britta Fritzsche, Simon Wehmeyer, Benjamin Schmidt, Paul Kachel, Christina Rolling, Julian Götze, Alina Busch, Marianne Sinn, Thais Pereira-Veiga, Harriet Wikman, Maria Geffken, Sven Peine, Urte
Publicado en: Journal of Experimental & Clinical Cancer Research, Edición 43, 2024, Página(s) 298, ISSN 1756-9966
Editor: BMC
DOI: 10.1186/s13046-024-03215-4

Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer

Autores: Jakob Nikolas Kather, Alexander T. Pearson, Niels Halama, Dirk Jäger, Jeremias Krause, Sven H. Loosen, Alexander Marx, Peter Boor, Frank Tacke, Ulf Peter Neumann, Heike I. Grabsch, Takaki Yoshikawa, Hermann Brenner, Jenny Chang-Claude, Michael Hoffmeister, Christian Trautwein, Tom Luedde
Publicado en: Nature Medicine, Edición 25/7, 2019, Página(s) 1054-1056, ISSN 1078-8956
Editor: Nature Publishing Group
DOI: 10.1038/s41591-019-0462-y

Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity

Autores: Ahmed Ghallab, Reham Hassan, Ute Hofmann, Adrian Friebel, Zaynab Hobloss, Lisa Brackhagen, Brigitte Begher-Tibbe, Maiju Myllys, Joerg Reinders, Nina Overbeck, Selahaddin Sezgin, Sebastian Zühlke, Abdel-Latif Seddek, Walaa Murad, Tim Brecklinghaus, Franziska Kappenberg, Jörg Rahnenführer, Daniela González, Christopher Goldring, Ian M Copple, Rosemarie Marchan, Thomas Longerich, Mihael Vucur, To
Publicado en: Journal of Hepatology, Edición 77/1, 2022, Página(s) 71-83, ISSN 0168-8278
Editor: Elsevier BV
DOI: 10.1016/j.jhep.2022.01.020

Decreased Bone Mineral Density Is a Predictor of Poor Survival in Critically Ill Patients.

Autores: Maximilian Schulze-Hagen; Christoph Roderburg; Theresa H. Wirtz; Markus S. Jördens; Lukas Bündgens; Samira Abu Jhaisha; Philipp Hohlstein; Jonathan F. Brozat; Philipp Bruners; Christina Loberg; Christiane K. Kuhl; Christian Trautwein; Frank Tacke; Tom Luedde; Sven H. Loosen; Alexander Koch
Publicado en: Journal of Clinical Medicine, Edición 10/16, 2021, Página(s) 3741, ISSN 2077-0383
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10163741

JNK signaling prevents biliary cyst formation through a CASPASE-8–dependent function of RIPK1 during aging

Autores: Katrin Müller, Hanna Honcharova-Biletska, Christiane Koppe, Michèle Egger, Lap Kwan Chan, Anne T. Schneider, Lena Küsgens, Friederike Böhm, Yannick Boege, Marc E. Healy, Johannes Schmitt, Sarah Comtesse, Mirco Castoldi, Christian Preisinger, Marta Szydlowska, Enrico Focaccia, Nadine T. Gaisa, Sven H. Loosen, Simone Jörs, Frank Tacke, Christoph Roderburg, Verena Keitel, Johannes G. Bode, Peter
Publicado en: Proceedings of the National Academy of Sciences, Edición 118/12, 2021, Página(s) e2007194118, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2007194118

Soluble lymphocyte activation gene-3 (sLAG3) and CD4/CD8 ratio dynamics as predictive biomarkers in patients undergoing immune checkpoint blockade for solid malignancies

Autores: Joao Gorgulho, Christoph Roderburg, Fabian Beier, Carsten Bokemeyer, Tim H. Brümmendorf, Sven H. Loosen, Tom Luedde
Publicado en: British Journal of Cancer, Edición 130, 2024, Página(s) 1013-1022, ISSN 0007-0920
Editor: Nature Publishing Group
DOI: 10.1038/s41416-023-02558-7

Non-Alcoholic Fatty Liver Disease (NAFLD) and risk of new-onset heart failure: a retrospective analysis of 173,966 patients

Autores: Christoph Roderburg, Sarah Krieg, Andreas Krieg, Sascha Vaghiri, Raphael Mohr, Marcel Konrad, Mark Luedde, Tom Luedde, Karel Kostev, Sven H. Loosen
Publicado en: Clinical Research in Cardiology, Edición 112, 2023, Página(s) 1446-1453, ISSN 1861-0684
Editor: Steinkopff
DOI: 10.1007/s00392-023-02250-z

Current Trends in Inpatient Care and In-Hospital Mortality of Cholangiocarcinoma in Germany: A Systematic Analysis between 2010 and 2019

Autores: Christoph Roderburg, Tobias Essing, Linde Kehmann, Sarah Krieg, Simon Labuhn, Jennis Kandler, Tom Luedde, Sven H Loosen
Publicado en: Cancers, Edición 14/16, 2022, Página(s) 4038, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14164038

Circulating levels of microRNA193a-5p predict outcome in early stage hepatocellular carcinoma

Autores: Sven H. Loosen, Theresa H. Wirtz, Sanchari Roy, Mihael Vucur, Mirco Castoldi, Anne T. Schneider, Christiane Koppe, Tom F. Ulmer, Anjali A. Roeth, Jan Bednarsch, Patrick H. Alizai, Pia Paffenholz, Münevver Demir, Christian Trautwein, Frank Tacke, Ulf P. Neumann, Christoph Roderburg, Tom Luedde
Publicado en: PLOS ONE, Edición 15/9, 2020, Página(s) e0239386, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0239386

Serum levels of soluble B and T lymphocyte attenuator predict overall survival in patients undergoing immune checkpoint inhibitor therapy for solid malignancies

Autores: Joao Gorgulho, Christoph Roderburg, Felix Heymann, Maximilian Schulze‐Hagen, Fabian Beier, Mihael Vucur, Jakob N. Kather, Narmin Ghaffari Laleh, Frank Tacke, Tim H. Brümmendorf, Tom Luedde, Sven H. Loosen
Publicado en: International Journal of Cancer, Edición 149/5, 2021, Página(s) 1189-1198, ISSN 0020-7136
Editor: John Wiley & Sons Inc.
DOI: 10.1002/ijc.33610

Serum Levels of Kisspeptin Are Elevated in Patients with Pancreatic Cancer

Autores: Sven H. Loosen, Mark Luedde, Georg Lurje, Martina Spehlmann, Pia Paffenholz, Tom Florian Ulmer, Frank Tacke, Mihael Vucur, Christian Trautwein, Ulf P. Neumann, Tom Luedde, Christoph Roderburg
Publicado en: Disease Markers, Edición 2019, 2019, Página(s) 1-8, ISSN 0278-0240
Editor: IOS Press
DOI: 10.1155/2019/5603474

The Role of Adipokines as Circulating Biomarkers in Critical Illness and Sepsis

Autores: Sven H. Loosen, Alexander Koch, Frank Tacke, Christoph Roderburg, Tom Luedde
Publicado en: International Journal of Molecular Sciences, Edición 20/19, 2019, Página(s) 4820, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20194820

Sublethal necroptosis signaling promotes inflammation and liver cancer

Autores: Mihael Vucur, Ahmed Ghallab, Anne T Schneider, Arlind Adili, Mingbo Cheng, Mirco Castoldi, Michael T Singer, Veronika Büttner, Leonie S Keysberg, Lena Küsgens, Marlene Kohlhepp, Boris Görg, Suchira Gallage, Jose Efren Barragan Avila, Kristian Unger, Claus Kordes, Anne-Laure Leblond, Wiebke Albrecht, Sven H Loosen, Carolin Lohr, Markus S Jördens, Anne Babler, Sikander Hayat, David Schumacher, M
Publicado en: Immunity, Edición 56/7, 2023, Página(s) 1578-1595, ISSN 1074-7613
Editor: Cell Press
DOI: 10.1016/j.immuni.2023.05.017

Serum Levels of CXCL13 Are an Independent Predictor of Survival Following Resection of Biliary Tract Cancer

Autores: Sven H Loosen, Tom F Ulmer, Simon Labuhn, Jan Bednarsch, Sven A Lang, Patrick H Alizai, Anne T Schneider, Mihael Vucur, Ulf P Neumann, Tom Luedde, Christoph Roderburg
Publicado en: Cancers, Edición 14/14, 2022, Página(s) 4073, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14174073

Adult Body Height Is Associated with the Risk of Type 2 but Not Type 1 Diabetes Mellitus: A Retrospective Cohort Study of 783,029 Individuals in Germany

Autores: Sven H Loosen, Sarah Krieg, Andreas Krieg, Tom Luedde, Karel Kostev, Christoph Roderburg
Publicado en: Journal of Clinical Medicine, Edición 12/6, 2023, Página(s) 2199, ISSN 2077-0383
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm12062199

Serum Levels of Soluble Urokinase Plasminogen Activator Receptor Predict Tumor Response and Outcome to Immune Checkpoint Inhibitor Therapy

Autores: Sven H. Loosen, Joao Gorgulho, Markus S. Jördens, Maximilian Schulze-Hagen, Fabian Beier, Mihael Vucur, Anne T. Schneider, Christiane Koppe, Alexander Mertens, Jakob N. Kather, Frank Tacke, Verena Keitel, Tim H. Brümmendorf, Christoph Roderburg, Tom Luedde
Publicado en: Frontiers in Oncology, Edición 11, 2021, ISSN 2234-943X
Editor: Frontiers Media S. A.
DOI: 10.3389/fonc.2021.646883

Progressive Sarcopenia Correlates with Poor Response and Outcome to Immune Checkpoint Inhibitor Therapy

Autores: Sven H. Loosen, Vincent van den Bosch, Joao Gorgulho, Maximilian Schulze-Hagen, Jennis Kandler, Markus S. Jördens, Frank Tacke, Christina Loberg, Gerald Antoch, Tim Brümmendorf, Ulf P. Neumann, Christiane Kuhl, Tom Luedde, Christoph Roderburg
Publicado en: Journal of Clinical Medicine, Edición 10/7, 2021, Página(s) 1361, ISSN 2077-0383
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10071361

TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation

Autores: Ibone Labiano, Aloña Agirre-Lizaso, Paula Olaizola, Anne Echebarria, Maider Huici-Izagirre, Irene Olaizola, Aitor Esparza-Baquer, Omar Sharif, Elizabeth Hijona, Piotr Milkiewicz, Malgorzata Milkiewicz, Francisco González-Romero, Patricia Aspichueta , Maria J Monte, Jose J G Marin, Mihael Vucur, Tom Luedde, Marco Marzioni, Derek A Mann , Luis Bujanda , Pedro M Rodrigues, Jesus M Banales, Maria J
Publicado en: Journal of Hepatology, Edición 77/4, 2022, Página(s) 991-1004, ISSN 1600-0641
Editor: Elsevier
DOI: 10.1016/j.jhep.2022.05.044

Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning

Autores: Amelie Echle, Heike Irmgard Grabsch, Philip Quirke, Piet A. van den Brandt, Nicholas P. West, Gordon G.A. Hutchins, Lara R. Heij, Xiuxiang Tan, Susan D. Richman, Jeremias Krause, Elizabeth Alwers, Josien Jenniskens, Kelly Offermans, Richard Gray, Hermann Brenner, Jenny Chang-Claude, Christian Trautwein, Alexander T. Pearson, Peter Boor, Tom Luedde, Nadine Therese Gaisa, Michael Hoffmeister, Jakob
Publicado en: Gastroenterology, Edición 159/4, 2020, Página(s) 1406-1416.e11, ISSN 0016-5085
Editor: W. B. Saunders Co., Ltd.
DOI: 10.1053/j.gastro.2020.06.021

Levels of Circulating PD-L1 Are Decreased in Patients with Resectable Cholangiocarcinoma

Autores: Christoph Roderburg, Sven H Loosen, Jan Bednarsch, Patrick H Alizai, Anjali A Roeth, Sophia M Schmitz, Mihael Vucur, Mark Luedde, Pia Paffenholz, Frank Tacke, Christian Trautwein, Tom F Ulmer, Ulf Peter Neumann, Tom Luedde
Publicado en: International Journal of Molecular Sciences, Edición 22/12, 2021, Página(s) 6569, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22126569

A20 Promotes Ripoptosome Formation and TNF-Induced Apoptosis via cIAPs Regulation and NIK Stabilization in Keratinocytes

Autores: Maria Feoktistova, Roman Makarov, Sihem Brenji, Anne T. Schneider, Guido J. Hooiveld, Tom Luedde, Martin Leverkus, Amir S. Yazdi, Diana Panayotova-Dimitrova
Publicado en: Cells, Edición 9/2, 2020, Página(s) 351, ISSN 2073-4409
Editor: MDPI (Multidisciplinary Digital Publishing Institute)
DOI: 10.3390/cells9020351

Clinical determinants of hospital mortality in liver failure: a comprehensive analysis of 62,717 patients

Autores: Tom Luedde; Sven H. Loosen; Tobias Essing; Hans Bock; Björn Wieland; Georg Fluegen; Jan Bednarsch; Johannes G. Bode; Ulf P. Neumann; Christoph Roderburg
Publicado en: Zeitschrift für Gastroenterologie, 2023, ISSN 1439-7803
Editor: Georg Thieme Verlag
DOI: 10.1055/a-2016-9061

Circulating levels of soluble urokinase plasminogen activator receptor predict outcome after resection of biliary tract cancer

Autores: Sven H. Loosen, Annemarie Breuer, Frank Tacke, Jakob N. Kather, Joao Gorgulho, Patrick H. Alizai, Jan Bednarsch, Anjali A. Roeth, Georg Lurje, Sophia M. Schmitz, Jonathan F. Brozat, Pia Paffenholz, Mihael Vucur, Thomas Ritz, Alexander Koch, Christian Trautwein, Tom F. Ulmer, Christoph Roderburg, Thomas Longerich, Ulf P. Neumann, Tom Luedde
Publicado en: JHEP Reports, Edición 2/2, 2020, Página(s) 100080, ISSN 2589-5559
Editor: Elsevier
DOI: 10.1016/j.jhepr.2020.100080

Serum levels of circulating microRNA-107 are elevated in patients with early-stage HCC

Autores: Sven H. Loosen, Mirco Castoldi, Markus S. Jördens, Sanchary Roy, Mihael Vucur, Jennis Kandler, Linda Hammerich, Raphael Mohr, Frank Tacke, Tom F. Ulmer, Ulf P. Neumann, Tom Luedde, Christoph Roderburg
Publicado en: PLOS ONE, Edición 16/3, 2021, Página(s) e0247917, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0247917

Elevated Serum Levels of CCL23 Are Associated with Poor Outcome after Resection of Biliary Tract Cancer

Autores: Christoph Roderburg, Simon Labuhn, Jan Bednarsch, Sven A Lang, Anne T Schneider, Linda Hammerich, Mihael Vucur, Tom F Ulmer, Ulf P Neumann, Tom Luedde, Sven H Loosen
Publicado en: Mediators of Inflammation, 2022, Página(s) 6195004, ISSN 0962-9351
Editor: Hindawi Publishing Corporation
DOI: 10.1155/2022/6195004

High baseline soluble urokinase plasminogen activator receptor (suPAR) serum levels indicate adverse outcome after resection of pancreatic adenocarcinoma

Autores: Sven H Loosen, Frank Tacke, Niklas Püthe, Marcel Binneboesel, Georg Wiltberger, Patrick H Alizai, Jakob N Kather, Pia Paffenholz, Thomas Ritz, Alexander Koch, Frank Bergmann, Christian Trautwein, Thomas Longerich, Christoph Roderburg, Ulf P Neumann, Tom Luedde
Publicado en: Carcinogenesis, Edición 40/8, 2019, Página(s) 947-955, ISSN 0143-3334
Editor: Oxford University Press
DOI: 10.1093/carcin/bgz033